News tagged ‘chemotherapy’ clear
- In a trio of studies presented at the 57th American Society of Hematology (ASH) Annual Meeting investigators from Dana-Farber shared results of clinical trials showing that new drug combinations can significantly extend the time in which multiple myeloma is kept in check in patients with relapsed or treatment-resistant forms of the disease.
Tags: chemotherapy, MultipleMyeloma
- In a span of five weeks beginning in late October, the U.S. Food and Drug Administration (FDA) gave approval to five new cancer drugs that proved effective in Dana-Farber-led clinical trials – and, in some cases, derive from basic research in Dana-Farber laboratories.
Tags: chemotherapy, BasicResearch, LungCancer, MultipleMyeloma, Sarcoma
- Men with metastatic, hormone-sensitive prostate cancer gained more than a year of survival when they received both hormone-blocking medications and chemotherapy right after diagnosis, rather than delaying the chemo until the cancer worsened, according to a study led by Dana-Farber’s Christopher Sweeney published in the New England Journal of Medicine.
Tags: chemotherapy, ProstateCancer
- Study led by Dr. Alexi Wright finds intraperitoneal chemotherapy substantially improves survival of ovarian cancer patients, but that many women who could benefit are not receiving the treatment.
Tags: chemotherapy, OvarianCancer
- Researchers report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant after pre-treatment with immunosuppressive drugs only. This is the first trial reporting successful transplant in dyskeratosis congenita (DC) patients without the use of any radiation or conventional cytotoxic chemotherapy beforehand.
Tags: chemotherapy, StemCellTransplant
- Based on results of a clinical trial led by Dana-Farber Cancer Institute scientists, the U.S. Food and Drug Administration (FDA) approved a targeted drug for advanced stomach cancer.
Tags: chemotherapy, TargetedTherapy
- Terminal cancer patients who receive chemotherapy in the last months of their lives are less likely to die where they want and are more likely to undergo invasive medical procedures than those who do not receive chemotherapy.
Tags: chemotherapy, EndOfLife
- A normal enzyme called SYK pairs with FLT3, the most commonly mutated enzyme found in acute myelogenous leukemia, to promote progression of the cancer and its resistance to treatment with FLT3-blocking drugs, which may explain relatively poor results in clinical studies. In a mouse model, treatment with a combination of drugs to inhibit the two enzymes was more effective than treatment with either drug alone.
Tags: chemotherapy, BasicResearch, ChildhoodCancer, Leukemia