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Older Adult Hematologic Malignancy (OHM) Program Research

  • Care for older adults with cancer is complex, as older patients tend to have multiple chronic conditions that need to managed along with their cancer diagnosis. Our program is actively involved in research focused on how best to care for older adults with hematologic malignancies.

    Research Studies

    Our main research study, Patient-Centered Care for the Older Adults with Hematologic Malignancies, evaluates the effectiveness of a geriatrician’s involvement in an older patient’s care team. Patients who participate in this study will have an initial assessment to assess frailty and will be randomized to have follow-up care with a geriatrician. Our research team will assess whether the involvement of a geriatrician helps to reduce frailty, improve outcomes, and decrease the number of non-scheduled hospital admissions.

    In addition, we offer many clinical trial opportunities for patients with blood cancers such as leukemia, lymphoma, multiple myeloma, and Waldenström’s macroglobulinemia. We encourage patients to speak with their care team to determine if a client trial is appropriate.

    Published Study Results

    Our team has published many findings related to the care of older adults with hematologic malignancies, including:

    • Geriatric assessment in older patients with acute myeloid leukemia: a retrospective study of associated treatment and outcomes (Sherman A, Motyckova G, Fega R, DeAngelo D, Abel G, Steensma D, Wadleigh M, Stone R, Driver JA.) Leukemia Res 2013;37(9):998-1003.
    • Non-hematologic predictors of mortality add prognostic value to International Prognostic Scoring System for MDS in older adults (Fega R, Abel G, Motyckova G, Sherman A, DeAngelo D, Steensma D, Galinsky I, Wadleigh M, Stone R, Driver, J) J Geriatr Oncol 2015;6:288-98.
    • Relationship between physician and patient assessment of performance status and survival in a large cohort of patients with hematologic malignancies (Liu M, Hshieh T, Condron N, Wadleigh M, Abel G, Driver J) Br J Cancer 2016 (in press).
    • Feasibility of routine frailty screening assessment for patients in a hematologic oncology clinic: Results from a pilot study (Abel G, Hshieh T, Condron N, Jacobson C, Steensma D, Laubach J, Stone R, Driver J)(abstract). Blood 2015; 126 (23): 3306.