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Status: RecruitingPhase: Phase 1Diagnosis: Multiple MyelomaNCT ID: NCT01562405
(View complete trial on ClinicalTrials.gov)
DFCI Protocol ID: 11-318
It is possible that the combination of lenalidomide, dexamethasone and ACE 011 may reduce or prevent the growth of cancer cells along with improving anemia and bone lesions that sometimes occur in people with multiple myeloma. This current study is the first study combining ACE 011 with lenalidomide. In this research study, the investigators are looking for the highest dose of ACE 011 that can be given with lenalidomide and dexamethasone. The investigators will also begin to collect information about the effect of the combination of ACE 011, lenalidomide and dexamethasone on multiple myeloma.
Conducting Institutions: Massachusetts General Hospital, Dana-Farber Cancer Institute, Brigham and Women's Hospital
Overall PI: Anuj Mahindra, M.D.,
Massachusetts General Hospital
Site-responsible Investigators: Jacob Laubach, MD,
Dana-Farber Cancer Institute
Contacts: Massachusetts General Hospital:
Cancer Trials Call Center, 877-789-6100