Improving Care After Chemotherapy

Status: Recruiting
Phase: N/A
Diagnosis: Gastrointestinal Malignancies
NCT ID: NCT01944137 (View complete trial on
DFCI Protocol ID: 13-258


The main purpose of this study is to examine changes in patient-reported symptoms during the first two cycles of neoadjuvant or adjuvant chemotherapy for non-small cell lung cancer (NSCLC) and colorectal cancer (CRC), among patients who receive standard care plus a proactive nursing intervention relative to patients who receive standard care alone. Interventions to improve symptom management and prevent urgent care needs in both the clinic and hospital for patients receiving chemotherapy with curative intent are needed to enhance the quality of cancer care.


Conducting Institutions:
Massachusetts General Hospital

Overall PI:
Theresa McDonnell, ACNP-BC, Massachusetts General Hospital

Site-responsible Investigators:

Massachusetts General Hospital: Cancer Trials Call Center, 877-789-6100

Eligibility Criteria

Inclusion Criteria: - Adult (age 18 or older) - Newly diagnosed stage I-III colorectal cancer or non-small-cell lung cancer - Scheduled to receive neoadjuvant chemotherapy (i.e. pre-surgical cancer-directed therapy with curative intent) or adjuvant chemotherapy (i.e. post-surgical cancer-directed therapy with curative intent) - Able to respond to questions in English Exclusion Criteria: - Already received 1 or more cycles of chemotherapy for the current regimen - Unwilling or unable to participate in the study
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