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Status: RecruitingPhase: Phase 0Diagnosis: Gastrointestinal Malignancies, Colorectal CancerNCT ID: NCT02172651
(View complete trial on ClinicalTrials.gov)
DFCI Protocol ID: 14-091
This study seeks to learn more about the vitamin D receptor and its relationship to colon cancer. The Vitamin D receptor is found in colon cancer cells. When Vitamin D binds to the receptor in the cancer cells, it may stop cancer cells from growing abnormally and may cause cancer cell death. Vitamin D has been used in other research studies and information from those other research studies suggests that Vitamin D may help in the treatment of colon cancer. Participants will receive either high-dose vitamin D or standard-dose vitamin D. The study drug will be given 14-28 days prior to your surgery. The number of days will depend on when the surgery is scheduled.
Conducting Institutions: Dana-Farber Cancer Institute, Brigham and Women's Hospital
Overall PI: Kimmie Ng, MD,
Dana-Farber Cancer Institute
Contacts: Dana-Farber Cancer Institute:
Gastrointestinal Research Line, 617-632-5960