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Status: RecruitingPhase: N/ADiagnosis: Brain/Neuro Cancer: Other Non-GlioblastomaNCT ID: NCT00657202
(View complete trial on ClinicalTrials.gov)
DFCI Protocol ID: 07-332
The purpose of this research study is to determine if ranibizumab can prevent the growth of neurofibromas. We will also be collecting extra blood and serum samples to help us learn more about NF1. Ranibizumab is a drug that affects the development of blood vessels that feed tumors. It targets a substance in the body called VEGF (Vascular Endothelial Growth Factor). VEGF helps tumors to grow and survive by supporting the growth of blood vessels that bring nutrients to the tumor. VEGF is made by cancerous tumors and also by non-cancerous tumors such as neurofibromas.
Conducting Institutions: Massachusetts General Hospital
Overall PI: Scott Plotkin, MD, PhD,
Massachusetts General Hospital
Contacts: Massachusetts General Hospital:
Cancer Trials Call Center, 877-789-6100