Charlotta Lindvall, MD, PhD

Charlotta Lindvall, MD, PhD

Palliative Medicine

Contact Information

Office Phone Number

617-632-6464

Researcher

Physician

Physician
Instructor in Medicine, Harvard Medical School

Centers/Programs

Board Certification

  • Hospice and Palliative Medicine
  • Internal Medicine

Fellowship

  • Dana-Farber Cancer Institute and Massachusetts General Hospital Palliative Care

Residency

  • MSU College of Human Medicine

Medical School

  • Karolinska Institutet, Stockholm, Sweden

Publications

    • Video Intervention and Goals-of-Care Documentation in Hospitalized Older Adults: The VIDEO-PCE Randomized Clinical Trial. JAMA Netw Open. 2023 09 05; 6(9):e2332556. View in: Pubmed

    • Depression care quality among patients with solid tumor cancers detected to have depression in Veterans Health Administration primary care clinics. Psychol Serv. 2023 Aug 24. View in: Pubmed

    • Forms or Free-Text? Measuring Advance Care Planning Activity Using Electronic Health Records. J Pain Symptom Manage. 2023 Aug 01. View in: Pubmed

    • Mitigating bias in AI at the point of care. Science. 2023 Jul 14; 381(6654):150-152. View in: Pubmed

    • What Patients Facing Cancer and Caregivers Want From Communication in Times of Crisis: A Qualitative Study in the Early Months of the COVID-19 Pandemic. Am J Hosp Palliat Care. 2023 Jun 30; 10499091231187351. View in: Pubmed

    • Measuring Palliative Care Communication via Telehealth: A Pilot Study. J Pain Symptom Manage. 2023 Jul; 66(1):e155-e161. View in: Pubmed

    • Development of a keyword library for capturing PRO-CTCAE-focused "symptom talk" in oncology conversations. JAMIA Open. 2023 Apr; 6(1):ooad009. View in: Pubmed

    • The Use of Natural Language Processing to Assess Social Support in Patients With Advanced Cancer. Oncologist. 2023 02 08; 28(2):165-171. View in: Pubmed

    • Shared Decision Making in the Geriatric Surgery Verification Program: Assessing Baseline Performance. J Pain Symptom Manage. 2023 06; 65(6):510-520.e3. View in: Pubmed

    • Delirium and Healthcare Utilization in Patients Undergoing Hematopoietic Stem Cell Transplantation. Transplant Cell Ther. 2023 05; 29(5):334.e1-334.e7. View in: Pubmed

    • Integrating Patient and Expert Perspectives to Conceptualize High-Quality Palliative Cancer Care for Symptoms in the US Veterans Health Administration: A Qualitative Study. Inquiry. 2023 Jan-Dec; 60:469580231160374. View in: Pubmed

    • Top Ten Tips Palliative Care Clinicians Should Know About Leveraging the Electronic Health Record for Data Collection and Quality Improvement. J Palliat Med. 2023 06; 26(6):849-855. View in: Pubmed

    • 21st Century Cures Act: ethical recommendations for new patient-facing products. J Am Med Inform Assoc. 2022 09 12; 29(10):1818-1822. View in: Pubmed

    • Opportunities for computational tools in palliative care: Supporting patient needs and lowering burden. Palliat Med. 2022 09; 36(8):1168-1170. View in: Pubmed

    • Study protocol for Video Images about Decisions to Improve Ethical Outcomes with Palliative Care Educators (VIDEO-PCE): a pragmatic stepped wedge cluster randomised trial of older patients admitted to the hospital BMJ Open. 2022 07 25; 12(7):e065236. View in: Pubmed

    • Surgeon-reported Factors Influencing Adoption of Quality Standards for Goal-concordant Care in Patients with Advanced Cancer: A Qualitative Study. Ann Surg. 2022 Jun 29. View in: Pubmed

    • Associations Between Family Member Involvement and Outcomes of Patients Admitted to the Intensive Care Unit: Retrospective Cohort Study. JMIR Med Inform. 2022 Jun 15; 10(6):e33921. View in: Pubmed

    • Natural Language Processing for Computer-Assisted Chart Review to Assess Documentation of Substance use and Psychopathology in Heart Failure Patients Awaiting Cardiac Resynchronization Therapy. J Pain Symptom Manage. 2022 10; 64(4):400-409. View in: Pubmed

    • Deep Learning for Cancer Symptoms Monitoring on the Basis of Electronic Health Record Unstructured Clinical Notes. JCO Clin Cancer Inform. 2022 06; 6:e2100136. View in: Pubmed

    • Leading from the Heart. J Pain Symptom Manage. 2022 06; 63(6):e645-e646. View in: Pubmed

    • Video Images about Decisions for Ethical Outcomes in Kidney Disease (VIDEO-KD): the study protocol for a multi-centre randomised controlled trial. BMJ Open. 2022 04 08; 12(4):e059313. View in: Pubmed

    • Patient Factors and Hospital Outcomes Associated With Atypical Presentation in Hospitalized Older Adults With COVID-19 During the First Surge of the Pandemic. J Gerontol A Biol Sci Med Sci. 2022 04 01; 77(4):e124-e132. View in: Pubmed

    • Association of an Advance Care Planning Video and Communication Intervention With Documentation of Advance Care Planning Among Older Adults: A Nonrandomized Controlled Trial. JAMA Netw Open. 2022 02 01; 5(2):e220354. View in: Pubmed

    • Randomized Trial of a Palliative Care Intervention to Improve End-of-Life Care Discussions in Patients With Metastatic Breast Cancer. J Natl Compr Canc Netw. 2022 02; 20(2):136-143. View in: Pubmed

    • Natural language processing for automated surveillance of intraoperative neuromonitoring in spine surgery. J Clin Neurosci. 2022 Mar; 97:121-126. View in: Pubmed

    • Correction to: Patient and Caregiver Prioritization of Palliative and End-of-Life Cancer Care Quality Measures. J Gen Intern Med. 2021 Nov 03. View in: Pubmed

    • Association of Social Support With Overall Survival and Healthcare Utilization in Patients With Aggressive Hematologic Malignancies. J Natl Compr Canc Netw. 2021 Oct 15; 1-7. View in: Pubmed

    • Patient and Caregiver Prioritization of Palliative and End-of-Life Cancer Care Quality Measures. J Gen Intern Med. 2022 05; 37(6):1429-1435. View in: Pubmed

    • Using nursing notes to improve clinical outcome prediction in intensive care patients: A retrospective cohort study. J Am Med Inform Assoc. 2021 07 30; 28(8):1660-1666. View in: Pubmed

    • Natural Language Processing to Identify Advance Care Planning Documentation in a Multisite Pragmatic Clinical Trial. J Pain Symptom Manage. 2022 01; 63(1):e29-e36. View in: Pubmed

    • Management of Pneumoperitoneum: Role and Limits of Nonoperative Treatment. Ann Surg. 2021 07 01; 274(1):146-154. View in: Pubmed

    • Deep learning to predict long-term mortality in patients requiring 7 days of mechanical ventilation. PLoS One. 2021; 16(6):e0253443. View in: Pubmed

    • Mining heterogeneous clinical notes by multi-modal latent topic model. PLoS One. 2021; 16(4):e0249622. View in: Pubmed

    • A Yet Unrealized Promise: Structured Advance Care Planning Elements in the Electronic Health Record. J Palliat Med. 2021 08; 24(8):1221-1225. View in: Pubmed

    • Artificial Intelligence-Aided Precision Medicine for COVID-19: Strategic Areas of Research and Development. J Med Internet Res. 2021 03 12; 23(3):e22453. View in: Pubmed

    • Natural Language Processing to Assess Frequency of Functional Status Documentation for Patients Newly Diagnosed With Colorectal Cancer-Reply. JAMA Oncol. 2021 03 01; 7(3):463. View in: Pubmed

    • Expert Stakeholder Prioritization of Process Quality Measures to Achieve Patient- and Family-Centered Palliative and End-of-Life Cancer Care. J Palliat Med. 2021 09; 24(9):1321-1333. View in: Pubmed

    • Exploring the Process of Cancer Care for Patients With Pre-Existing Mobility Disability. JCO Oncol Pract. 2021 01; 17(1):e53-e61. View in: Pubmed

    • Prevalence, Management, and Outcomes Related to Preoperative Medical Orders for Life Sustaining Treatment (MOLST) in an Adult Surgical Population: Preoperative MOLST and Code Status Discussions. Ann Surg. 2023 Jan 01; 277(1):109-115. View in: Pubmed

    • Latent bias and the implementation of artificial intelligence in medicine. J Am Med Inform Assoc. 2020 12 09; 27(12):2020-2023. View in: Pubmed

    • Use of Natural Language Processing to Assess Frequency of Functional Status Documentation for Patients Newly Diagnosed With Colorectal Cancer. JAMA Oncol. 2020 10 01; 6(10):1628-1630. View in: Pubmed

    • Identifying Goals of Care Conversations in the Electronic Health Record Using Natural Language Processing and Machine Learning. J Pain Symptom Manage. 2021 01; 61(1):136-142.e2. View in: Pubmed

    • Measure Scan and Synthesis of Palliative and End-of-Life Process Quality Measures for Advanced Cancer. JCO Oncol Pract. 2021 02; 17(2):e140-e148. View in: Pubmed

    • Advance Care Planning: Promoting Effective and Aligned Communication in the Elderly (ACP-PEACE): the study protocol for a pragmatic stepped-wedge trial of older patients with cancer. BMJ Open. 2020 07 14; 10(7):e040999. View in: Pubmed

    • Shortlist of Quality Indicators for End-of-Life Cancer Care. JAMA Oncol. 2020 07 01; 6(7):1118-1119. View in: Pubmed

    • Adherence and Concordance between Serious Illness Care Planning Conversations and Oncology Clinician Documentation among Patients with Advanced Cancer. J Palliat Med. 2021 01; 24(1):53-62. View in: Pubmed

    • Deep Natural Language Processing to Identify Symptom Documentation in Clinical Notes for Patients With Heart Failure Undergoing Cardiac Resynchronization Therapy. J Pain Symptom Manage. 2020 11; 60(5):948-958.e3. View in: Pubmed

    • Long-Term Prognosis of Older Adults Who Survive Emergency Mechanical Ventilation. J Pain Symptom Manage. 2020 11; 60(5):1019-1026. View in: Pubmed

    • Challenges of Developing a Natural Language Processing Method With Electronic Health Records to Identify Persons With Chronic Mobility Disability. Arch Phys Med Rehabil. 2020 10; 101(10):1739-1746. View in: Pubmed

    • Automated machine learning: Review of the state-of-the-art and opportunities for healthcare. Artif Intell Med. 2020 04; 104:101822. View in: Pubmed

    • Deep Natural Language Processing Identifies Variation in Care Preference Documentation. J Pain Symptom Manage. 2020 06; 59(6):1186-1194.e3. View in: Pubmed

    • Natural Language Processing to Assess Palliative Care and End-of-Life Process Measures in Patients With Breast Cancer With Leptomeningeal Disease. Am J Hosp Palliat Care. 2020 May; 37(5):371-376. View in: Pubmed

    • Can machine learning improve patient selection for cardiac resynchronization therapy? PLoS One. 2019; 14(10):e0222397. View in: Pubmed

    • Variation in Serious Illness Communication among Surgical Patients Receiving Palliative Care. J Palliat Med. 2020 03; 23(3):411-414. View in: Pubmed

    • Differences by Race, Religiosity, and Mental Health in Preferences for Life-Prolonging Treatment Among Medicare Beneficiaries. J Gen Intern Med. 2019 10; 34(10):1981-1983. View in: Pubmed

    • Natural Language Processing Accurately Measures Adherence to Best Practice Guidelines for Palliative Care in Trauma. J Pain Symptom Manage. 2020 02; 59(2):225-232.e2. View in: Pubmed

    • Deficits in the Palliative Care Process Measures in Patients with Advanced Pancreatic Cancer Undergoing Operative and Invasive Nonoperative Palliative Procedures. Ann Surg Oncol. 2019 Dec; 26(13):4204-4212. View in: Pubmed

    • Documentation of Palliative and End-of-Life Care Process Measures Among Young Adults Who Died of Cancer: A Natural Language Processing Approach. J Adolesc Young Adult Oncol. 2020 02; 9(1):100-104. View in: Pubmed

    • US National Trends in Opioid-Related Hospitalizations Among Patients With Cancer. JAMA Oncol. 2019 May 01; 5(5):734-735. View in: Pubmed

    • Risk factors and prevalence of liver disease in review of 2557 routine liver biopsies performed during bariatric surgery. Surg Obes Relat Dis. 2019 Jun; 15(6):843-849. View in: Pubmed

    • Goals-of-Care Conversations for Older Adults With Serious Illness in the Emergency Department: Challenges and Opportunities. Ann Emerg Med. 2019 08; 74(2):276-284. View in: Pubmed

    • In-hospital mortality in older patients after ventricular assist device implantation: A national cohort study. J Thorac Cardiovasc Surg. 2019 08; 158(2):466-475.e4. View in: Pubmed

    • Deep learning algorithms to identify documentation of serious illness conversations during intensive care unit admissions. Palliat Med. 2019 02; 33(2):187-196. View in: Pubmed

    • Natural Language Processing to Assess End-of-Life Quality Indicators in Cancer Patients Receiving Palliative Surgery. J Palliat Med. 2019 02; 22(2):183-187. View in: Pubmed

    • Needle in a Haystack: Natural Language Processing to Identify Serious Illness. J Palliat Med. 2019 02; 22(2):179-182. View in: Pubmed

    • Machine Learning to Predict, Detect, and Intervene Older Adults Vulnerable for Adverse Drug Events in the Emergency Department. J Med Toxicol. 2018 09; 14(3):248-252. View in: Pubmed

    • Postoperative outcomes in patients with a do-not-resuscitate (DNR) order undergoing elective procedures. J Clin Anesth. 2018 Aug; 48:81-88. View in: Pubmed

    • Measuring Processes of Care in Palliative Surgery: A Novel Approach Using Natural Language Processing. Ann Surg. 2018 05; 267(5):823-825. View in: Pubmed

    • Machine Learning Methods to Extract Documentation of Breast Cancer Symptoms From Electronic Health Records. J Pain Symptom Manage. 2018 06; 55(6):1492-1499. View in: Pubmed

    • A Pilot Study to Evaluate Compliance with Guidelines for Preprocedural Reconsideration of Code Status Limitations. J Palliat Med. 2018 08; 21(8):1152-1156. View in: Pubmed

    • Using Electronic Health Records for Quality Measurement and Accountability in Care of the Seriously Ill: Opportunities and Challenges. J Palliat Med. 2018 03; 21(S2):S52-S60. View in: Pubmed

    • Prognosis, Communication, and Advance Care Planning in Heart Failure: A Module for Students, Residents, Fellows, and Practicing Clinicians. MedEdPORTAL. 2017 Jun 16; 13:10596. View in: Pubmed

    • Increasing sex differences in the use of cardiac resynchronization therapy with or without implantable cardioverter-defibrillator. Eur Heart J. 2017 May 14; 38(19):1485-1494. View in: Pubmed

    • The Intensive Palliative Care Unit: Changing Outcomes for Hospitalized Cancer Patients in an Academic Medical Center. J Palliat Med. 2017 03; 20(3):285-289. View in: Pubmed

    • National Trends in the Use of Cardiac Resynchronization Therapy With or Without Implantable Cardioverter-Defibrillator. Circulation. 2016 Jan 19; 133(3):273-81. View in: Pubmed

    • The Intensive Palliative Care Unit (IPCU): Changing outcomes for hospitalized cancer patients in an academic medical center. J Clin Oncol. 2015 Oct 10; 33(29_suppl):135. View in: Pubmed

    • Teaching colleagues how to discuss prognosis as part of a hospital-wide quality improvement project: the positive impact of a 90-minute workshop. J Pain Symptom Manage. 2015 May; 49(5):960-3. View in: Pubmed

    • Overcoming the barriers to palliative care referral for patients with advanced heart failure. J Am Heart Assoc. 2014 Feb 28; 3(1):e000742. View in: Pubmed

    • Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells. Oncogene. 2013 Sep 05; 32(36):4203-13. View in: Pubmed

    • LRP6 mediates cAMP generation by G protein-coupled receptors through regulating the membrane targeting of Ga(s). Sci Signal. 2011 Mar 15; 4(164):ra15. View in: Pubmed

    • Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of Apc and Pten in the mouse salivary gland: implications for human acinic cell carcinoma. Cancer Res. 2010 Nov 15; 70(22):9143-52. View in: Pubmed

    • The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage. PLoS One. 2009 Aug 12; 4(8):e6594. View in: Pubmed

    • The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development. PLoS One. 2009 Jun 05; 4(6):e5813. View in: Pubmed

    • Gene targeting approaches in mice: assessing the roles of LRP5 and LRP6 in osteoblasts. J Musculoskelet Neuronal Interact. 2008 Oct-Dec; 8(4):291-3. View in: Pubmed

    • Cdc7-Dbf4 kinase overexpression in multiple cancers and tumor cell lines is correlated with p53 inactivation. Neoplasia. 2008 Sep; 10(9):920-31. View in: Pubmed

    • Wnt signaling, stem cells, and the cellular origin of breast cancer. Stem Cell Rev. 2007 Jun; 3(2):157-68. View in: Pubmed

    • Phosphoinositide 3-kinase regulates a subset of interferon-alpha-stimulated genes. Exp Cell Res. 2007 Jan 15; 313(2):404-14. View in: Pubmed

    • The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis. J Biol Chem. 2006 Nov 17; 281(46):35081-7. View in: Pubmed

    • TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell. 2006 Sep 08; 126(5):955-68. View in: Pubmed

    • Epstein-Barr virus latent membrane 2A (LMP2A) down-regulates telomerase reverse transcriptase (hTERT) in epithelial cell lines. Int J Cancer. 2005 Jan 10; 113(2):284-9. View in: Pubmed

    • Combined genetic and transcriptional profiling of acute myeloid leukemia with normal and complex karyotypes. Haematologica. 2004 Sep; 89(9):1072-81. View in: Pubmed

    • Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies. Blood. 2004 Jan 01; 103(1):229-35. View in: Pubmed

    • Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene. Cancer Res. 2003 Apr 15; 63(8):1743-7. View in: Pubmed

    • Deletion of the telomerase reverse transcriptase gene and haploinsufficiency of telomere maintenance in Cri du chat syndrome. Am J Hum Genet. 2003 Apr; 72(4):940-8. View in: Pubmed

    • Genomic characterization of MOZ/CBP and CBP/MOZ chimeras in acute myeloid leukemia suggests the involvement of a damage-repair mechanism in the origin of the t(8;16)(p11;p13). Genes Chromosomes Cancer. 2003 Jan; 36(1):90-8. View in: Pubmed

    • Amplification of the telomerase reverse transcriptase (hTERT) gene in cervical carcinomas. Genes Chromosomes Cancer. 2002 Jul; 34(3):269-75. View in: Pubmed

    • Simian AIDS-related lymphoma growth in severe combined immunodeficiency mice is independent of karyotypic abnormalities or Bcl-6 mutations. AIDS Res Hum Retroviruses. 2002 Mar 20; 18(5):383-90. View in: Pubmed

    • Molecular cytogenetic characterization of acute myeloid leukemia and myelodysplastic syndromes with multiple chromosome rearrangements. Haematologica. 2001 Nov; 86(11):1158-64. View in: Pubmed

    • Frequent amplification of the telomerase reverse transcriptase gene in human tumors. Cancer Res. 2000 Nov 15; 60(22):6230-5. View in: Pubmed

    • RT-PCR analysis of the MOZ-CBP and CBP-MOZ chimeric transcripts in acute myeloid leukemias with t(8;16)(p11;p13). Genes Chromosomes Cancer. 2000 Aug; 28(4):415-24. View in: Pubmed

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    450 Brookline Avenue Boston, MA 02215
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    Dana-Farber Cancer Institute

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    Dana-Farber Cancer Institute

    450 Brookline Avenue Boston, MA 02215
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