You can feel confident in the treatment at the Lank Center for Genitourinary Oncology at Dana-Farber Brigham Cancer Center, as our specialists focus exclusively on genitourinary cancers. If you need surgery, radiation therapy, or chemotherapy, you will see experts in each area who specifically treat kidney cancer. Our experts see over 200 kidney cancer patients each year, giving you an unmatched level of treatment expertise. Studies have shown that recovery and survival rates are higher for patients who are treated at a comprehensive medical center with a multidisciplinary team of experts, like those found at the Lank Center.
Multidisciplinary Approach
Our clinical and support teams are not just here to manage your cancer; they are here to care for you. We create a unique treatment plan for every patient, and we consider all aspects of your health when making our recommendations.
Our multidisciplinary team includes experienced urologists, surgical oncologists, medical oncologists, radiation oncologists, radiologists, pathologists, researchers, nurses, physician assistants, and social workers who treat, counsel, and care for each patient with dedication and compassion. You have the advantage of meeting with your entire medical team in a single visit. Your team will also meet regularly to review your health and treatment options and ensure you receive the best possible care.
Beginning with your first appointment, our nurses will walk you through the entire treatment process, making sure you know what to expect and where to find helpful resources, such as counseling, nutrition advice, or palliative care. In addition, each patient has a personal social worker to provide extra support and guidance.
Kidney Cancer Treatment by Stage
Depending on how much the cancer has spread, you may have one treatment or a combination of treatments. Treatment depends largely on the stage and spread of the disease, but your overall health and age are always considered before treatment. Most early-stage cancers can be treated successfully with surgery, but clinical trials and targeted therapies may be recommended at any stage of the disease.
- With stage I kidney cancer, surgery is generally the only treatment necessary. Surgery at this stage may include the removal of a portion of the kidney or the entire kidney, plus surrounding tissues. After surgery, most patients will be monitored closely to make sure the cancer does not return. In some cases of newly diagnosed kidney cancer, a clinical trial or targeted therapy may be suggested.
- If you are diagnosed with stage II kidney cancer, a portion of your kidney or the entire kidney may be removed, along with surrounding, affected tissues. Clinical trials, targeted therapies, or hormone therapy may be suggested at this stage, as well
- Stage III kidney cancer will likely include clinical trials or targeted therapies. This stage may or may not require surgery to remove the entire kidney and surrounding affected tissues and organs. In rare cases, chemotherapy will be included in treatment for stage III kidney cancer
- If you are diagnosed with stage IV kidney cancer, treatment will generally include clinical trials or targeted therapies. Surgery is rarely performed at stage IV. In some cases, radiation or chemotherapy treatments may be introduced to ease pain and symptoms, and improve quality of life.
Surgery
Surgical approaches to the treatment of kidney cancer include:
- Partial nephrectomy: Removes only the part of the kidney with the tumor.
- Radical nephrectomy: Removes the whole kidney, sometimes the adrenal gland, tissue around the kidney, and surrounding lymph nodes.
- Traditional open nephrectomy (partial or radical): Performed through a flank or abdominal incision.
- Robot-assisted laparoscopic nephrectomy (partial or radical): Removes all or part of the kidney using telescopic instruments inserted in the abdomen through small incisions.
- Tumor ablation: Destroys the tumor without surgically removing it. Ablative technologies include cryotherapy and radiofrequency ablation.
Medical Oncology
Medical oncologists are doctors who study cancer tumors and deliver chemotherapy (drugs that eliminate cancer cells or stop them from dividing). Medical oncologists at Dana-Farber Brigham Cancer Center offer the most effective therapies possible, while helping you maintain your quality of life during treatment.
Our specialists are constantly testing and studying new combinations of chemotherapy drugs to improve outcomes, decrease side effects, and slow tumor growth or recurrence. The experts at Dana-Farber Brigham Cancer Center will also work closely with you, should you require targeted therapies, immunotherapy, clinical trials, or more rarely, chemotherapy.
Targeted Therapies
Targeted therapy is a treatment that uses drugs or other substances to locate and attack specific cancer cells without harming healthy cells. The kidneys have a large number of blood vessels that may enable cancer cells to spread and multiply more than they would in other organs. However, the blood vessels of the kidneys respond well to anti-angiogenic drugs (drugs that target the blood vessels leading to the tumor but don't harm normal blood vessels). Targeted therapies are generally introduced in treatment for patients with later stages of kidney cancer.
Immunotherapy
Immunotherapy is a type of treatment that uses the patient's immune system to fight cancer cells. Substances made by the body, or in a lab, may be used to boost, drive, or restore a patient's immune system defenses against cancer. Immunotherapy is occasionally used for metastatic cases of kidney cancer, but side effects are often difficult to tolerate.
Chemotherapy
Chemotherapy is not the preferred method to treat kidney cancer. Chemotherapy for kidney cancer is generally reserved for rare cases when patients are not responding to hormone therapy, targeted therapy, or surgery.
When chemotherapy is indicated, it is provided at Dana-Farber's Yawkey Center for Cancer Care, one of the most advanced outpatient cancer centers in the country — designed for patients, by patients.
Radiation Oncology
Radiation therapy for kidney cancer is rarely recommended. Kidney tumors do not respond well to radiation, as healthy kidneys can be harmed in the process. In rare cases, radiation may be used to relieve pain and symptoms when the cancer has spread beyond the kidney to other organs in the body. In these cases, the disease is usually quite advanced, and patients are not good candidates for surgery. If radiation is recommended, our expert team of radiation oncologists will carefully choose the most appropriate, high-tech therapy for your cancer.