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Adrenocortical carcinoma: a rare disease in which malignant
(cancer) cells form in the cortex (outer layer) of the adrenal gland
Adrenocortical carcinoma, also known as adrenal cortical
carcinoma (ACC), is a rare and aggressive cancer that originates in the outer
layer of the adrenal gland. There are two adrenal glands. One sits on top of
each kidney. The adrenal cortex makes important hormones, including ones that
keep water and salt in balance, control blood pressure, and help the body use
energy. Adrenocortical tumors usually make extra amounts of one or more adrenal
hormones, which may cause symptoms. Certain inherited disorders increase the
risk of adrenocortical cancer; these include Li-Fraumeni syndrome,
Beckwith-Wiedemann syndrome, and Carney complex.
Learn about adrenocortical carcinoma, and find information
on how we support and care for adults with adrenocortical carcinoma before,
during, and after treatment.
The following information is from the National Cancer
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