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CAR T-Cell Therapy for Leukemia

  • Hematologic Oncology nurse Ilene Galinsky, BSN, NP, and physician Daniel DeAngelo, MD, PhD

    Leukemia nurse practitioner Ilene Galinsky and physician Daniel DeAngelo

  • CAR T-cell therapy is a promising treatment for patients with many types of blood cancer, including leukemia. It is a highly-specialized therapy that involves genetically modifying a patient's own T cells to attack their cancer.

    Learn more about CAR T-cell therapy.

    CAR T-cell therapy is FDA-approved for patients with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL).

    Patients are evaluated carefully to determine if this therapy is appropriate for them, and are cared for by a team experienced in CAR T-cell therapy.

    In addition to the FDA-approved therapy, Dana-Farber Brigham Cancer Center also offers clinical trials evaluating CAR T-cell therapy for other types of leukemia, as well as other blood cancers.

    Key Eligibility Criteria for CAR T-Cell Therapy for Leukemia

    Key eligibility criteria include:

    • Confirmed diagnosis of B-cell acute lymphoblastic leukemia (ALL) that has either not responded or has relapsed after at least two lines of prior treatment.
    • Adequate organ, cardiac, and pulmonary function (must meet established criteria/measures).

    Children and young adults may also be evaluated at Dana-Farber/Boston Children's Cancer and Blood Disorders Center (Dana-Farber/Boston Children's).

  • Dana-Farber Brigham Cancer Center logo
  • Contact Information for CAR T-Cell Therapy

    For more information about CAR T-cell therapy, please call 877-801-CART (2278).

  • Pediatric CAR T-Cell Therapy

    Dana-Farber/Boston Children's is a certified treatment center for providing the recently FDA-approved CAR T-cell therapy called KYMRIAH® to patients who are up to 25 years old with second or later relapsed or refractory B-cell acute lymphoblastic leukemia (ALL).