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What Is Childhood Adrenocortical Carcinoma?

  • Adrenocortical carcinoma is a rare cancer that forms in the outer layer of the adrenal gland, which release hormones such as adrenaline to control heart rate, blood pressure and other body functions.

    Adrenocortical carcinoma usually affects children who are younger than 4 or older than 13. These tumors, which frequently secrete hormones and may cause patients to develop masculine traits (regardless of gender), can spread to the kidneys, lungs, bones and brain. Many children with adrenocortical carcinoma have have Li-Fraumeni syndrome, an inherited condition that predisposes them to many types of cancer.

    Adrenocortical carcinoma treatment at Dana-Farber/Boston Children’s

    Children and adolescents with adrenocortical carcinoma are treated through the Rare Tumors Center at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. Because Dana-Farber/Boston Children's is one of the largest pediatric cancer centers in the world, our specialists develop a deeper expertise in each sub-type of pediatric cancer, including rare tumors like adrenocroticol carcinoma.

    Learn more about adrenocortical carcinoma

    Find in-depth information on adrenocortical carcinoma on the Dana-Farber/Boston Children's website, including details on adrenocortical carcinoma symptoms, diagnosis and treatment.