Exercise Intervention among Men with Prostate Cancer Initiating Androgen Deprivation Therapy: Pilot Study
Trial Description
This research study is evaluating the impact and feasibility of a 12-week brisk walking and
moderate strength training exercise intervention including a virtual component in men who are
initiating androgen deprivation therapy (ADT) for prostate cancer
Eligibility Requirements
Inclusion Criteria:
- Written informed consent prior to any study-related procedures
- History of histologically confirmed prostate cancer
- Initiating or within 30 days of initiating ADT
- ECOG performance status of 0 or 1
- At least 18 years old and no older than 80 years
- Physically able to exercise and have physician consent from their treating physician
to start a physical activity program
- English speaking and able to read English
- Have access to and are able to use the internet at a minimum of once per week
- Sufficient proficiency and confidence to use the internet and follow video-based
instructions, as determined by the eligibility questionnaire to be completed by the
participant
- Willingness to be randomized
Exclusion Criteria:
- Self-reported inability to walk 2 blocks (at any pace)
- Currently physically active (> 90 minutes of moderate or vigorous physical activity
per week) as determined by Leisure Score Index of Godin Leisure-Time Exercise
Questionnaire [LSI])
- Previously on ADT
- Radiologic evidence of distant disease
- Cardiovascular, respiratory or musculoskeletal disease or joint problems that preclude
moderate physical activity. Examples would include unstable angina, recent myocardial
infarction, oxygen-dependent pulmonary disease, and osteoarthritis requiring imminent
joint replacement. Moderate arthritis that does not preclude physical activity is not
a reason for ineligibility.
- Psychiatric disorders or conditions that would preclude participation in the study
intervention (e.g., untreated major depression or psychosis, substance abuse, severe
personality disorder)