REVITALIZE: A Telehealth Intervention for Women with Advanced Ovarian Cancer and PARP Inhibitor-Related Fatigue

NOT ENROLLING
Protocol # :
20-285
Conditions
Ovarian Cancer
Fatigue
Coping Behavior
Coping Skills
Phase
Feasibility / Pilot
Disease Sites
Ovary
Principal Investigator
Wright, Alexi, A

Trial Description

This study is testing whether a 6 week skills-based telehealth intervention can help ovarian
cancer patients experiencing PARP inhibitor-related fatigue reduce the impact of fatigue on
their daily life and activities.

Eligibility Requirements

Inclusion Criteria:

- Women ≥18 years of age who have been diagnosed with epithelial ovarian, fallopian
tube, or primary peritoneal carcinoma.

- Receiving PARPI inhibitors for ≥ 2 months.

- Able to read/speak English.

- Have an Eastern Oncology Group (ECOG) performance of 0-2.

- Report moderate-severe fatigue in the past week (average score ≥4 on a Fatigue Symptom
Inventory scale of 0-10)

Exclusion Criteria:

- Patients with an untreated clinical condition or comorbid illness (e.g. anemia,
hypothyroidism) that could explain their fatigue.

- Patients with chronic severe fatigue that pre-dates their use of PARPi.

- The following special populations will be excluded from this research:

- Adults unable to consent

- Individuals who are not yet adults (infants, children, teenagers)

- Pregnant women

- Prisoners

20-285