Kimmie Ng, MD, MPH

Kimmie Ng, MD, MPH

Medical Oncology

Contact Information

Office Phone Number

617-632-4150

Fax

617-632-5370

Appointments

617-632-3680

Biography

Kimmie Ng, MD, MPH

Dr. Kimmie Ng is Associate Chief of the Division of Gastrointestinal Oncology at Dana-Farber Cancer Institute, and an Associate Professor of Medicine at Harvard Medical School in Boston, MA. She serves as Co-Director of the Colon and Rectal Cancer Center and the Director of Translational Research in the division. She is also the Founding Director of the Young-Onset Colorectal Cancer Center at Dana-Farber, one of the first of its kind in the country. Her research focuses on identifying dietary, plasma, and molecular predictors of improved survival in patients with colorectal cancer, with a special interest in the vitamin D pathway, the microbiome, and young-onset colorectal cancer. Her research has been funded by the National Cancer Institute, Cancer Research UK, U.S. Department of Defense, and other foundation and industry grants. She has been featured in multiple national media outlets, including the TODAY Show, MSNBC, ABC News, The New York Times, CNN, The Washington Post, and the Wall Street Journal, to raise awareness of young-onset colorectal cancer and the importance of cancer screening.

Dr. Ng's clinical practice involves the care of patients with all types of gastrointestinal cancers. As Director of Translational Research, she oversees the Gastrointestinal Cancer Biobank and facilitates translational research projects with academic and industry collaborators. She is also involved in the design and conduct of clinical trials, and has served as Principal Investigator of several national multi-center randomized trials.

Dr. Ng obtained her Bachelor of Science degree with Distinction from Yale University and her Doctor of Medicine degree from University of Pennsylvania Perelman School of Medicine. She completed her residency in internal medicine at University of California, San Francisco (UCSF) and a medical oncology fellowship at Dana-Farber/Partners CancerCare. She subsequently received a Master of Public Health degree from Harvard T.H. Chan School of Public Health.

Researcher

Physician

Associate Chief, Division of Gastrointestinal Oncology
Director, Young-Onset Colorectal Cancer Center
Co-Director, Colon and Rectal Cancer Center
Director of Translational Research, Division of Gastrointestinal Oncology
Physician
Associate Professor of Medicine, Harvard Medical School

Centers/Programs

Clinical Interests

Gastrointestinal cancers

Board Certification

  • Internal Medicine, 2004
  • Medical Oncology, 2017

Fellowship

  • Dana-Farber/Partners CancerCare, Medical Oncology

Residency

  • University of California, San Francisco, Internal Medicine

Medical School

  • Harvard School of Public Health
  • University of Pennsylvania School of Medicine

Research

    Dr. Ng is a board-certified medical oncologist with MD and MPH degrees who specializes in the treatment and investigation of gastrointestinal malignancies. In her role as Director of Translational Research for the Gastrointestinal Cancer Center at Dana-Farber Cancer Institute, she facilitates collaborative projects with laboratory scientists across academia and industry, and leads clinical trials of novel therapeutics. Her research program aims to identify dietary, molecular, and genetic predictors of improved survival in patients with colorectal cancer, with a focus on the vitamin D pathway and the microbiome. In March 2019, she founded the Young-Onset Colorectal Cancer Center at Dana-Farber Cancer Institute - among the first centers of its kind in the world - to spearhead a multidisciplinary research effort to elucidate the underlying causes of the increased incidence and mortality of young-onset colorectal cancer. She has received multiple grants for her work, including K07, R01, and P50 SPORE awards from the National Cancer Institute to evaluate the role of vitamin D in colorectal cancer; a DOD Translational Team Science Award to investigate mechanisms of resistance to EGFR inhibitors; and a Cancer Research UK Grand Challenge award to investigate the role of the microbiome in colorectal cancer.

    Publications

      • Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping. Nat Med. 2024 Mar; 30(3):907. View in: Pubmed

      • RAS/RAF co-mutation and ERBB2 copy number modulates HER2 heterogeneity and responsiveness to HER2-directed therapy in colorectal cancer. Clin Cancer Res. 2024 Feb 12. View in: Pubmed

      • Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders. J Immunother Cancer. 2024 01 25; 12(1). View in: Pubmed

      • Cancer Diagnoses After Recent Weight Loss. JAMA. 2024 01 23; 331(4):318-328. View in: Pubmed

      • Systematic literature review and meta-analysis of HER2 amplification, overexpression, and positivity in colorectal cancer. JNCI Cancer Spectr. 2024 Jan 04; 8(1). View in: Pubmed

      • Benchmarking mismatch repair testing for patients with cancer receiving immunotherapy. Cancer Cell. 2024 01 08; 42(1):6-7. View in: Pubmed

      • A Phase I Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-dose Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma. Clin Cancer Res. 2023 12 15; 29(24):5047-5056. View in: Pubmed

      • Reply. Clin Gastroenterol Hepatol. 2023 Dec 07. View in: Pubmed

      • Reply. Clin Gastroenterol Hepatol. 2023 Nov 17. View in: Pubmed

      • Oncogenic Drivers and Therapeutic Vulnerabilities in KRAS Wild-Type Pancreatic Cancer. Clin Cancer Res. 2023 11 14; 29(22):4627-4643. View in: Pubmed

      • Liquid biopsy epigenomic profiling for cancer subtyping. Nat Med. 2023 Nov; 29(11):2737-2741. View in: Pubmed

      • Sex-Specific Associations between Adiponectin and Leptin Signaling and Pancreatic Cancer Survival. Cancer Epidemiol Biomarkers Prev. 2023 10 02; 32(10):1458-1469. View in: Pubmed

      • Being Breastfed in Infancy and Risk of Colorectal Cancer and Precursor Lesions. Clin Gastroenterol Hepatol. 2023 Sep 06. View in: Pubmed

      • Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer. Nat Commun. 2023 07 18; 14(1):4317. View in: Pubmed

      • Plasma 25-Hydroxyvitamin D Levels and Survival in Stage III Colon Cancer: Findings from CALGB/SWOG 80702 (Alliance). Clin Cancer Res. 2023 07 14; 29(14):2621-2630. View in: Pubmed

      • The "scope" of colorectal cancer screening in Lynch syndrome: is there an optimal interval? J Natl Cancer Inst. 2023 07 06; 115(7):775-777. View in: Pubmed

      • Sequential apoptotic and multiplexed proteomic evaluation of single cancer cells. Sci Adv. 2023 06 23; 9(25):eadg4128. View in: Pubmed

      • Bayesian risk prediction model for colorectal cancer mortality through integration of clinicopathologic and genomic data. NPJ Precis Oncol. 2023 Jun 10; 7(1):57. View in: Pubmed

      • G-CSF rescue of FOLFIRINOX-induced neutropenia leads to systemic immune suppression in mice and humans. J Immunother Cancer. 2023 06; 11(6). View in: Pubmed

      • Highly Sensitive Circulating Tumor DNA Assay Aids Clinical Management of Radiographically Occult Isolated Peritoneal Metastases in Patients With GI Cancer. JCO Precis Oncol. 2023 06; 7:e2200572. View in: Pubmed

      • Prediagnostic Vitamin D Status and Colorectal Cancer Survival by Vitamin D Binding Protein Isoforms in US Cohorts. J Clin Endocrinol Metab. 2023 05 17; 108(6):e223-e229. View in: Pubmed

      • Helicobacter pylori Seropositivity, ABO Blood Type, and Pancreatic Cancer Risk From 5 Prospective Cohorts. Clin Transl Gastroenterol. 2023 05 01; 14(5):e00573. View in: Pubmed

      • Pancreatic cancer is associated with medication changes prior to clinical diagnosis. Nat Commun. 2023 04 28; 14(1):2437. View in: Pubmed

      • Flavonoid intake and survival after diagnosis of colorectal cancer: a prospective study in 2 US cohorts. Am J Clin Nutr. 2023 06; 117(6):1121-1129. View in: Pubmed

      • A common cancer at an uncommon age. Science. 2023 03 17; 379(6637):1088-1090. View in: Pubmed

      • Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer. JCO Precis Oncol. 2023 01; 7:e2200342. View in: Pubmed

      • Incident Early- and Later-Onset Type 2 Diabetes and Risk of Early- and Later-Onset Cancer: Prospective Cohort Study. Diabetes Care. 2023 01 01; 46(1):120-129. View in: Pubmed

      • Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer. Clin Cancer Res. 2022 12 01; 28(23):5167-5179. View in: Pubmed

      • Endoscopic Screening and Risk of Colorectal Cancer according to Type 2 Diabetes Status. Cancer Prev Res (Phila). 2022 12 01; 15(12):847-856. View in: Pubmed

      • Age at Initiation of Lower Gastrointestinal Endoscopy and Colorectal Cancer Risk Among US Women. JAMA Oncol. 2022 07 01; 8(7):986-993. View in: Pubmed

      • RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition. Nat Commun. 2022 06 08; 13(1):3181. View in: Pubmed

      • Sugar-sweetened beverage and sugar consumption and colorectal cancer incidence and mortality according to anatomic subsite. Am J Clin Nutr. 2022 06 07; 115(6):1481-1489. View in: Pubmed

      • Colorectal Cancer: Advancing Science, Improving Access, and Refining Therapy. Hematol Oncol Clin North Am. 2022 06; 36(3):xiii-xiv. View in: Pubmed

      • Cetuximab and Irinotecan With or Without Bevacizumab in Refractory Metastatic Colorectal Cancer: BOND-3, an ACCRU Network Randomized Clinical Trial. Oncologist. 2022 04 05; 27(4):292-298. View in: Pubmed

      • Survival in Young-Onset Metastatic Colorectal Cancer: Findings From Cancer and Leukemia Group B (Alliance)/SWOG 80405. J Natl Cancer Inst. 2022 03 08; 114(3):427-435. View in: Pubmed

      • Age and comorbidity association with survival outcomes in metastatic colorectal cancer: CALGB 80405 analysis. J Geriatr Oncol. 2022 05; 13(4):469-479. View in: Pubmed

      • Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer. Cell. 2021 12 09; 184(25):6119-6137.e26. View in: Pubmed

      • Unrestrained eating behavior and risk of digestive system cancers: a prospective cohort study. Am J Clin Nutr. 2021 11 08; 114(5):1612-1624. View in: Pubmed

      • Individual participant data (IPD)-level meta-analysis of randomised controlled trials to estimate the vitamin D dietary requirements in dark-skinned individuals resident at high latitude. Eur J Nutr. 2022 Mar; 61(2):1015-1034. View in: Pubmed

      • Trifluridine/Tipiracil and Regorafenib in Patients with Metastatic Colorectal Cancer: A Retrospective Study at a Tertiary Oncology Center. Oncologist. 2021 12; 26(12):e2161-e2169. View in: Pubmed

      • Unrestrained eating behavior and risk of mortality: A prospective cohort study. Clin Nutr. 2021 11; 40(11):5419-5429. View in: Pubmed

      • Immune cell profiles in the tumor microenvironment of early-onset, intermediate-onset, and later-onset colorectal cancer. Cancer Immunol Immunother. 2022 Apr; 71(4):933-942. View in: Pubmed

      • Prediagnostic Inflammation and Pancreatic Cancer Survival. J Natl Cancer Inst. 2021 09 04; 113(9):1186-1193. View in: Pubmed

      • Spatially organized multicellular immune hubs in human colorectal cancer. Cell. 2021 09 02; 184(18):4734-4752.e20. View in: Pubmed

      • Sugar-sweetened beverage, artificially sweetened beverage and sugar intake and colorectal cancer survival. Br J Cancer. 2021 09; 125(7):1016-1024. View in: Pubmed

      • Total Vitamin D Intake and Risks of Early-Onset Colorectal Cancer and Precursors. Gastroenterology. 2021 10; 161(4):1208-1217.e9. View in: Pubmed

      • Can an apple a day keep cancer away? Am J Clin Nutr. 2021 Jun; 113(6):1388-1389. View in: Pubmed

      • Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database. JAMA Netw Open. 2021 06 01; 4(6):e2112539. View in: Pubmed

      • Can an apple a day keep cancer away? Am J Clin Nutr. 2021 06 01; 113(6):1388-1389. View in: Pubmed

      • US Preventive Services Task Force Recommendations for Colorectal Cancer Screening: Forty-Five Is the New Fifty. JAMA. 2021 05 18; 325(19):1943-1945. View in: Pubmed

      • Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women. Gut. 2021 12; 70(12):2330-2336. View in: Pubmed

      • Coffee Consumption and Colorectal Cancer Prognosis-Reply. JAMA Oncol. 2021 05 01; 7(5):779-780. View in: Pubmed

      • FGFR2 Extracellular Domain In-Frame Deletions Are Therapeutically Targetable Genomic Alterations That Function as Oncogenic Drivers in Cholangiocarcinoma. Cancer Discov. 2021 10; 11(10):2488-2505. View in: Pubmed

      • Tumor Long Interspersed Nucleotide Element-1 (LINE-1) Hypomethylation in Relation to Age of Colorectal Cancer Diagnosis and Prognosis. Cancers (Basel). 2021 Apr 22; 13(9). View in: Pubmed

      • Simple Sugar and Sugar-Sweetened Beverage Intake During Adolescence and Risk of Colorectal Cancer Precursors. Gastroenterology. 2021 07; 161(1):128-142.e20. View in: Pubmed

      • Aspirin Use and Risk of Colorectal Cancer Among Older Adults. JAMA Oncol. 2021 Mar 01; 7(3):428-435. View in: Pubmed

      • NGS-based identification and tracing of microsatellite instability from minute amounts DNA using inter-Alu-PCR. Nucleic Acids Res. 2021 02 26; 49(4):e24. View in: Pubmed

      • Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment. Clin Cancer Res. 2021 05 15; 27(10):2816-2826. View in: Pubmed

      • Smoking Modifies Pancreatic Cancer Risk Loci on 2q21.3. Cancer Res. 2021 06 01; 81(11):3134-3143. View in: Pubmed

      • Preexisting Type 2 Diabetes and Survival among Patients with Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2021 04; 30(4):757-764. View in: Pubmed

      • Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions. Clin Cancer Res. 2021 03 15; 27(6):1695-1705. View in: Pubmed

      • Lead-Time Trajectory of CA19-9 as an Anchor Marker for Pancreatic Cancer Early Detection. Gastroenterology. 2021 03; 160(4):1373-1383.e6. View in: Pubmed

      • Rising incidence of early-onset colorectal cancer - a call to action. Nat Rev Clin Oncol. 2021 04; 18(4):230-243. View in: Pubmed

      • Association of Coffee Intake With Survival in Patients With Advanced or Metastatic Colorectal Cancer. JAMA Oncol. 2020 Nov 01; 6(11):1713-1721. View in: Pubmed

      • Association of Diet Quality With Survival Among People With Metastatic Colorectal Cancer in the Cancer and Leukemia B and Southwest Oncology Group 80405 Trial. JAMA Netw Open. 2020 10 01; 3(10):e2023500. View in: Pubmed

      • Diabetes, Weight Change, and Pancreatic Cancer Risk. JAMA Oncol. 2020 10 01; 6(10):e202948. View in: Pubmed

      • A Transcriptome-Wide Association Study Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer. J Natl Cancer Inst. 2020 10 01; 112(10):1003-1012. View in: Pubmed

      • Prediagnostic Circulating Concentrations of Vitamin D Binding Protein and Survival among Patients with Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2020 11; 29(11):2323-2331. View in: Pubmed

      • Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial. Cancer Prev Res (Phila). 2020 12; 13(12):1055-1062. View in: Pubmed

      • Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy. Cancer Discov. 2020 11; 10(11):1690-1705. View in: Pubmed

      • Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk. Cancer Res. 2020 09 15; 80(18):4004-4013. View in: Pubmed

      • Vitamin D supplementation: a potential therapeutic agent for metastatic colorectal cancer. Br J Cancer. 2020 10; 123(8):1205-1206. View in: Pubmed

      • Genome-Wide Gene-Diabetes and Gene-Obesity Interaction Scan in 8,255 Cases and 11,900 Controls from PanScan and PanC4 Consortia. Cancer Epidemiol Biomarkers Prev. 2020 09; 29(9):1784-1791. View in: Pubmed

      • High-throughput dynamic BH3 profiling may quickly and accurately predict effective therapies in solid tumors. Sci Signal. 2020 06 16; 13(636). View in: Pubmed

      • Acid-suppressive medications and risk of colorectal cancer: results from three large prospective cohort studies. Br J Cancer. 2020 09; 123(5):844-851. View in: Pubmed

      • The Diet of Higher Insulinemic Potential Is Not Associated with Worse Survival in Patients with Stage III Colon Cancer (Alliance). Cancer Epidemiol Biomarkers Prev. 2020 08; 29(8):1692-1695. View in: Pubmed

      • Insulin-Like Growth Factor-1 Receptor Expression and Disease Recurrence and Survival in Patients with Resected Pancreatic Ductal Adenocarcinoma. Cancer Epidemiol Biomarkers Prev. 2020 08; 29(8):1586-1595. View in: Pubmed

      • Genetic and Circulating Biomarker Data Improve Risk Prediction for Pancreatic Cancer in the General Population. Cancer Epidemiol Biomarkers Prev. 2020 05; 29(5):999-1008. View in: Pubmed

      • Obesity and efficacy of vitamin D3 supplementation in healthy black adults. Cancer Causes Control. 2020 Apr; 31(4):303-307. View in: Pubmed

      • The effects of age on clinical characteristics, hospitalization and mortality of patients with influenza-related illness at a tertiary care centre in Malaysia. Influenza Other Respir Viruses. 2020 05; 14(3):286-293. View in: Pubmed

      • A phase 2 clinical trial of the heat shock protein 90 (HSP 90) inhibitor ganetespib in patients with refractory advanced esophagogastric cancer. Invest New Drugs. 2020 10; 38(5):1533-1539. View in: Pubmed

      • Randomized Phase II Trial of Exercise, Metformin, or Both on Metabolic Biomarkers in Colorectal and Breast Cancer Survivors. JNCI Cancer Spectr. 2020 Feb; 4(1):pkz096. View in: Pubmed

      • Diabetes and Clinical Outcome in Patients With Metastatic Colorectal Cancer: CALGB 80405 (Alliance). JNCI Cancer Spectr. 2020 Feb; 4(1):pkz078. View in: Pubmed

      • Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance). Clin Cancer Res. 2019 12 15; 25(24):7497-7505. View in: Pubmed

      • Postdiagnosis Loss of Skeletal Muscle, but Not Adipose Tissue, Is Associated with Shorter Survival of Patients with Advanced Pancreatic Cancer. Cancer Epidemiol Biomarkers Prev. 2019 12; 28(12):2062-2069. View in: Pubmed

      • Prediagnostic Leukocyte Telomere Length and Pancreatic Cancer Survival. Cancer Epidemiol Biomarkers Prev. 2019 11; 28(11):1868-1875. View in: Pubmed

      • Associations of Physical Activity With Survival and Progression in Metastatic Colorectal Cancer: Results From Cancer and Leukemia Group B (Alliance)/SWOG 80405. J Clin Oncol. 2019 10 10; 37(29):2620-2631. View in: Pubmed

      • Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair-Deficient Colorectal Cancer. Cancer Immunol Res. 2019 08; 7(8):1230-1236. View in: Pubmed

      • Influence of genetic variation in the vitamin D pathway on plasma 25-hydroxyvitamin D3 levels and survival among patients with metastatic colorectal cancer. Cancer Causes Control. 2019 Jul; 30(7):757-765. View in: Pubmed

      • Treatment Patterns Among De Novo Metastatic Cancer Patients Who Died Within 1 Month of Diagnosis. JNCI Cancer Spectr. 2019 Jun; 3(2):pkz021. View in: Pubmed

      • Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial. JAMA. 2019 04 09; 321(14):1370-1379. View in: Pubmed

      • FOLFOX plus ziv-aflibercept or placebo in first-line metastatic esophagogastric adenocarcinoma: A double-blind, randomized, multicenter phase 2 trial. Cancer. 2019 07 01; 125(13):2213-2221. View in: Pubmed

      • Family history of cancer, Ashkenazi Jewish ancestry, and pancreatic cancer risk. Br J Cancer. 2019 04; 120(8):848-854. View in: Pubmed

      • Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial. Eur J Cancer. 2019 04; 111:82-93. View in: Pubmed

      • Calcium Intake and Risk of Colorectal Cancer According to Tumor-infiltrating T Cells. Cancer Prev Res (Phila). 2019 05; 12(5):283-294. View in: Pubmed

      • Dietary Insulin Load and Cancer Recurrence and Survival in Patients With Stage III Colon Cancer: Findings From CALGB 89803 (Alliance). J Natl Cancer Inst. 2019 02 01; 111(2):170-179. View in: Pubmed

      • Sedentary Behaviors, TV Viewing Time, and Risk of Young-Onset Colorectal Cancer. JNCI Cancer Spectr. 2018 Nov; 2(4):pky073. View in: Pubmed

      • Association of Obesity With Risk of Early-Onset Colorectal Cancer Among Women. JAMA Oncol. 2019 01 01; 5(1):37-44. View in: Pubmed

      • Calcium Intake and Survival after Colorectal Cancer Diagnosis. Clin Cancer Res. 2019 03 15; 25(6):1980-1988. View in: Pubmed

      • Vitamin D status after colorectal cancer diagnosis and patient survival according to immune response to tumour. Eur J Cancer. 2018 11; 103:98-107. View in: Pubmed

      • Phase 1 dose-escalation study of momelotinib, a Janus kinase 1/2 inhibitor, combined with gemcitabine and nab-paclitaxel in patients with previously untreated metastatic pancreatic ductal adenocarcinoma. Invest New Drugs. 2019 02; 37(1):159-165. View in: Pubmed

      • Associations of artificially sweetened beverage intake with disease recurrence and mortality in stage III colon cancer: Results from CALGB 89803 (Alliance). PLoS One. 2018; 13(7):e0199244. View in: Pubmed

      • Viral Load and Sequence Analysis Reveal the Symptom Severity, Diversity, and Transmission Clusters of Rhinovirus Infections. Clin Infect Dis. 2018 07 02; 67(2):261-268. View in: Pubmed

      • Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine. Cancer Discov. 2018 09; 8(9):1096-1111. View in: Pubmed

      • Association of Survival With Adherence to the American Cancer Society Nutrition and Physical Activity Guidelines for Cancer Survivors After Colon Cancer Diagnosis: The CALGB 89803/Alliance Trial. JAMA Oncol. 2018 06 01; 4(6):783-790. View in: Pubmed

      • Grain Intake and Clinical Outcome in Stage III Colon Cancer: Results From CALGB 89803 (Alliance). JNCI Cancer Spectr. 2018 Feb; 2(2):pky017. View in: Pubmed

      • Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma. JAMA Oncol. 2018 Mar 08; 4(3):e173420. View in: Pubmed

      • Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance). J Clin Oncol. 2018 04 10; 36(11):1112-1120. View in: Pubmed

      • Prediagnosis Use of Statins Associates With Increased Survival Times of Patients With Pancreatic Cancer. Clin Gastroenterol Hepatol. 2018 08; 16(8):1300-1306.e3. View in: Pubmed

      • Statin use and pancreatic cancer risk in two prospective cohort studies. J Gastroenterol. 2018 Aug; 53(8):959-966. View in: Pubmed

      • Regular Use of Aspirin or Non-Aspirin Nonsteroidal Anti-Inflammatory Drugs Is Not Associated With Risk of Incident Pancreatic Cancer in Two Large Cohort Studies. Gastroenterology. 2018 04; 154(5):1380-1390.e5. View in: Pubmed

      • Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer. Science. 2017 12 15; 358(6369):1443-1448. View in: Pubmed

      • Factors That Contribute to Differences in Survival of Black vs White Patients With Colorectal Cancer. Gastroenterology. 2018 03; 154(4):906-915.e7. View in: Pubmed

      • Lymph node metastases in resected pancreatic ductal adenocarcinoma: predictors of disease recurrence and survival. Br J Cancer. 2017 Dec 05; 117(12):1874-1882. View in: Pubmed

      • Tumor expression of calcium sensing receptor and colorectal cancer survival: Results from the nurses' health study and health professionals follow-up study. Int J Cancer. 2017 12 15; 141(12):2471-2479. View in: Pubmed

      • Influence of dietary insulin scores on survival in colorectal cancer patients. Br J Cancer. 2017 Sep 26; 117(7):1079-1087. View in: Pubmed

      • Calcium intake and risk of colorectal cancer according to expression status of calcium-sensing receptor (CASR). Gut. 2018 08; 67(8):1475-1483. View in: Pubmed

      • Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome. J Clin Oncol. 2017 Jul 01; 35(19):2165-2172. View in: Pubmed

      • Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers. Cancer Cell. 2017 04 10; 31(4):576-590.e8. View in: Pubmed

      • To Treat or Not to Treat: Adjuvant Therapy for Stage II Colon Cancer in the Era of Precision Oncology. J Oncol Pract. 2017 04; 13(4):242-244. View in: Pubmed

      • Cigarette Smoking and Pancreatic Cancer Survival. J Clin Oncol. 2017 Jun 01; 35(16):1822-1828. View in: Pubmed

      • Dietary glycemic and insulin scores and colorectal cancer survival by tumor molecular biomarkers. Int J Cancer. 2017 06 15; 140(12):2648-2656. View in: Pubmed

      • Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer. J Clin Oncol. 2017 Apr 01; 35(10):1086-1095. View in: Pubmed

      • Pancreatic Cancer Risk Associated with Prediagnostic Plasma Levels of Leptin and Leptin Receptor Genetic Polymorphisms. Cancer Res. 2016 12 15; 76(24):7160-7167. View in: Pubmed

      • Leucocyte telomere length, genetic variants at the TERT gene region and risk of pancreatic cancer. Gut. 2017 06; 66(6):1116-1122. View in: Pubmed

      • Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Rep. 2016 10 18; 17(4):1206. View in: Pubmed

      • Prediagnostic Plasma 25-Hydroxyvitamin D and Pancreatic Cancer Survival. J Clin Oncol. 2016 08 20; 34(24):2899-905. View in: Pubmed

      • Plasma 25-Hydroxyvitamin D, Vitamin D Binding Protein, and Risk of Colorectal Cancer in the Nurses' Health Study. Cancer Prev Res (Phila). 2016 Aug; 9(8):664-72. View in: Pubmed

      • Vitamin D and Physical Activity in Patients With Colorectal Cancer: Epidemiological Evidence and Therapeutic Implications. Cancer J. 2016 May-Jun; 22(3):223-31. View in: Pubmed

      • Vitamin D and colorectal cancer: molecular, epidemiological and clinical evidence. Br J Nutr. 2016 05; 115(9):1643-60. View in: Pubmed

      • Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Rep. 2016 Apr 26; 15(4):857-865. View in: Pubmed

      • Soluble tumour necrosis factor receptor type II and survival in colorectal cancer. Br J Cancer. 2016 04 26; 114(9):995-1002. View in: Pubmed

      • Diversity and Evolutionary Histories of Human Coronaviruses NL63 and 229E Associated with Acute Upper Respiratory Tract Symptoms in Kuala Lumpur, Malaysia. Am J Trop Med Hyg. 2016 05 04; 94(5):1058-64. View in: Pubmed

      • Circulating Metabolites and Survival Among Patients With Pancreatic Cancer. J Natl Cancer Inst. 2016 Jun; 108(6):djv409. View in: Pubmed

      • Reduction of Parathyroid Hormone with Vitamin D Supplementation in Blacks: A Randomized Controlled Trial. BMC Nutr. 2015; 1. View in: Pubmed

      • Co-infections and transmission networks of HCV, HIV-1 and HPgV among people who inject drugs. Sci Rep. 2015 Oct 13; 5:15198. View in: Pubmed

      • Prediagnostic Plasma Adiponectin and Survival among Patients with Colorectal Cancer. Cancer Prev Res (Phila). 2015 Dec; 8(12):1138-45. View in: Pubmed

      • Stereotactic Body Radiotherapy (SBRT) for Intrahepatic and Hilar Cholangiocarcinoma. J Cancer. 2015; 6(11):1099-104. View in: Pubmed

      • Effects of Vitamin D Supplementation on C-peptide and 25-hydroxyvitamin D Concentrations at 3 and 6 Months. Sci Rep. 2015 Jun 22; 5:10411. View in: Pubmed

      • Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer. Carcinogenesis. 2015 Sep; 36(9):999-1007. View in: Pubmed

      • Response. J Natl Cancer Inst. 2015 Aug; 107(8). View in: Pubmed

      • Association Between Plasma Levels of Macrophage Inhibitory Cytokine-1 Before Diagnosis of Colorectal Cancer and Mortality. Gastroenterology. 2015 Sep; 149(3):614-22. View in: Pubmed

      • Plasma 25-hydroxyvitamin D and colorectal cancer risk according to tumour immunity status. Gut. 2016 Feb; 65(2):296-304. View in: Pubmed

      • Aspirin and COX-2 inhibitor use in patients with stage III colon cancer. J Natl Cancer Inst. 2015 Jan; 107(1):345. View in: Pubmed

      • Survival among patients with pancreatic cancer and long-standing or recent-onset diabetes mellitus. J Clin Oncol. 2015 Jan 01; 33(1):29-35. View in: Pubmed

      • Designing a multidisciplinary oral chemotherapy education and monitoring program. J Clin Oncol. 2014 Oct 20; 32(30_suppl):146. View in: Pubmed

      • Vitamin D for Prevention and Treatment of Colorectal Cancer: What is the Evidence? Curr Colorectal Cancer Rep. 2014 Sep 01; 10(3):339-345. View in: Pubmed

      • Reply to PM Brannon et al. Am J Clin Nutr. 2014 Sep; 100(3):984-6. View in: Pubmed

      • Null association between vitamin D and PSA levels among black men in a vitamin D supplementation trial. Cancer Epidemiol Biomarkers Prev. 2014 Sep; 23(9):1944-7. View in: Pubmed

      • HIV-1 transmission networks among men who have sex with men in Asia. Clin Infect Dis. 2014 Sep 15; 59(6):910-1. View in: Pubmed

      • Predicted 25(OH)D score and colorectal cancer risk according to vitamin D receptor expression. Cancer Epidemiol Biomarkers Prev. 2014 Aug; 23(8):1628-37. View in: Pubmed

      • Phase II and pharmacodynamic study of autophagy inhibition using hydroxychloroquine in patients with metastatic pancreatic adenocarcinoma. Oncologist. 2014 Jun; 19(6):637-8. View in: Pubmed

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      • Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2013 Nov; 22(11):2037-46. View in: Pubmed

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      • Multicenter phase II study of tivozanib (AV-951) and everolimus (RAD001) for patients with refractory, metastatic colorectal cancer. Oncologist. 2013; 18(4):377-8. View in: Pubmed

      • Multi-drug inhibition of the HER pathway in metastatic colorectal cancer: results of a phase I study of pertuzumab plus cetuximab in cetuximab-refractory patients. Invest New Drugs. 2014 Feb; 32(1):113-22. View in: Pubmed

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      • Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer. J Clin Oncol. 2009 Jan 10; 27(2):176-85. View in: Pubmed

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