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Shoshana Rosenberg, ScD, MPH


Medical Oncology/Population Sciences


Researcher

  • Assistant Professor of Medicine, Dana-Farber Cancer Institute
  • Assistant Professor of Medicine, Harvard Medical School

Contact Information

  • Office Phone Number617-582-7593

Bio

Dr. Rosenberg received her BA from Binghamton University, completed a Master of Public Health degree at NYU and a Doctor of Science degree in Epidemiology at the Harvard T.H. Chan School of Public Health. Following an NCI post-doctoral fellowship in Cancer Prevention, a joint program between the Harvard T.H Chan School of Public Health and Dana-Farber Cancer Institute, she was appointed to the faculty of Dana-Farber Cancer Institute and Harvard Medical School.

Fellowship:

  • DFCI/HSPH

Research

Our research focuses on improving the care and outcomes of young women with breast cancer



I am a cancer epidemiologist with an interest in the unique issues affecting young women with breast cancer; my research focuses on survivorship, quality of life, and treatment decision-making in this population. Intervention development is a core focus of my research. In 2015, I was awarded a K01 career development grant by the Agency for Healthcare Research and Quality to conduct a mixed-methods study that aims to ultimately improve the quality of the surgical decision-making process for young women with breast cancer. As part of this project, I am leading a pilot study of a decision aid intervention for newly-diagnosed young women considering their breast cancer surgical options. 



Incorporating patient-reported outcomes (PROs) into both observational and intervention trials has also been an important focus of my work and this experience will help inform survey development for the proposed project. As a member of the Alliance for Clinical Trials in Oncology - Health Outcomes Committee as well as the Translational Breast Cancer Research Consortium PRO Working Group, I advise clinical trialists on how best to implement PROs into the design of clinical trials. Additionally, I am a co-investigator for a PCORI contract, where I help lead the study aim that will examine PROs among women who are diagnosed with DCIS.

Kim HJ, Dominici L, Rosenberg SM, Zheng Y, Pak LM, Poorvu PD, Ruddy KJ, Tamimi R, Schapira L, Come SE, Peppercorn J, Borges VF, Warner E, Vardeh H, Collins LC, Gaither R, King TA, Partridge AH. Surgical Treatment after Neoadjuvant Systemic Therapy in Young Women with Breast Cancer: Results from a Prospective Cohort Study. Ann Surg. 2020 Dec 23; Publish Ahead of Print.
View in: PubMed

Poorvu PD, Gelber SI, Zheng Y, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Lambertini M, Rosenberg SM, Partridge AH. Pregnancy after breast cancer: Results from a prospective cohort of young women with breast cancer. Cancer. 2020 Dec 01.
View in: PubMed

Pak LM, Gaither R, Rosenberg SM, Ruddy KJ, Tamimi RM, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Snow C, Collins LC, King TA, Partridge AH. Tumor phenotype and concordance in synchronous bilateral breast cancer in young women. Breast Cancer Res Treat. 2020 Nov 26.
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Sella T, Gelber SI, Poorvu PD, Kim HJ, Dominici L, Guzman-Arocho YD, Collins L, Ruddy KJ, Tamimi RM, Peppercorn JM, Schapira L, Borges VF, Come SE, Warner E, Snow C, Jakubowski DM, Russell CA, Winer EP, Rosenberg SM, Partridge AH. Response to neoadjuvant chemotherapy and the 21-gene Breast Recurrence Score test in young women with estrogen receptor-positive early breast cancer. Breast Cancer Res Treat. 2020 Nov 04.
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Rosenberg SM, Dominici LS, Gelber S, Poorvu PD, Ruddy KJ, Wong JS, Tamimi RM, Schapira L, Come S, Peppercorn JM, Borges VF, Partridge AH. Association of Breast Cancer Surgery With Quality of Life and Psychosocial Well-being in Young Breast Cancer Survivors. JAMA Surg. 2020 11 01; 155(11):1035-1042.
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Cook EE, Rosenberg SM, Ruddy KJ, Barry WT, Greaney M, Ligibel J, Sprunck-Harrild K, Holmes MD, Tamimi RM, Emmons KM, Partridge AH. Prospective evaluation of the impact of stress, anxiety, and depression on household income among young women with early breast cancer from the Young and Strong trial. BMC Public Health. 2020 Oct 06; 20(1):1514.
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Rosenberg SM, Petrie KJ, Stanton AL, Ngo L, Finnerty E, Partridge AH. Interventions to Enhance Adherence to Oral Antineoplastic Agents: A Scoping Review. J Natl Cancer Inst. 2020 05 01; 112(5):443-465.
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Dominici LS, Rosenberg SM. Ductal carcinoma in situ (DCIS): The importance of patient-reported outcomes (PRO). Curr Breast Cancer Rep. 2020 Jun; 12(2):90-97.
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Parsons HA, Rhoades J, Reed SC, Gydush G, Ram P, Exman P, Xiong K, Lo CC, Li T, Fleharty M, Kirkner GJ, Rotem D, Cohen O, Yu F, Fitarelli-Kiehl M, Leong KW, Hughes ME, Rosenberg SM, Collins LC, Miller KD, Blumenstiel B, Trippa L, Cibulskis C, Neuberg DS, DeFelice M, Freeman SS, Lennon NJ, Wagle N, Ha G, Stover DG, Choudhury AD, Getz G, Winer EP, Meyerson M, Lin NU, Krop I, Love JC, Makrigiorgos GM, Partridge AH, Mayer EL, Golub TR, Adalsteinsson VA. Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer. Clin Cancer Res. 2020 06 01; 26(11):2556-2564.
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Poorvu PD, Gelber SI, Rosenberg SM, Ruddy KJ, Tamimi RM, Collins LC, Peppercorn J, Schapira L, Borges VF, Come SE, Warner E, Jakubowski DM, Russell C, Winer EP, Partridge AH. Prognostic Impact of the 21-Gene Recurrence Score Assay Among Young Women With Node-Negative and Node-Positive ER-Positive/HER2-Negative Breast Cancer. J Clin Oncol. 2020 03 01; 38(7):725-733.
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Lee GE, Rosenberg SM, Mayer EL, Borges V, Meyer ME, Schapira L, Come SE, Partridge AH. Contemporary management of breast cancer during pregnancy and subsequent lactation in a multicenter cohort of young women with breast cancer. Breast J. 2019 11; 25(6):1104-1110.
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Rosenberg SM, Vaz-Luis I, Gong J, Rajagopal PS, Ruddy KJ, Tamimi RM, Schapira L, Come S, Borges V, de Moor JS, Partridge AH. Employment trends in young women following a breast cancer diagnosis. Breast Cancer Res Treat. 2019 Aug; 177(1):207-214.
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Wassermann J, Gelber SI, Rosenberg SM, Ruddy KJ, Tamimi RM, Schapira L, Borges VF, Come SE, Meyer ME, Partridge AH. Nonadherent behaviors among young women on adjuvant endocrine therapy for breast cancer. Cancer. 2019 09 15; 125(18):3266-3274.
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Rosenberg SM, Greaney ML, Patenaude AF, Partridge AH. Factors Affecting Surgical Decisions in Newly Diagnosed Young Women with Early-Stage Breast Cancer. J Adolesc Young Adult Oncol. 2019 08; 8(4):463-468.
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Rosenberg SM, Ligibel JA, Meyerhardt JA, Jacobsen ED, Garber JE, Nekhlyudov L, Bunnell CA, Nutting P, Sprunck-Harrild K, Walsh SK, Partridge AH. Developing a Novel Model to Improve Research and care for Cancer Survivors: a Feasibility Study. J Cancer Educ. 2019 04; 34(2):229-233.
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von Hippel C, Rosenberg SM, Austin SB, Sprunck-Harrild K, Ruddy KJ, Schapira L, Come S, Borges VF, Partridge AH. Identifying distinct trajectories of change in young breast cancer survivors' sexual functioning. Psychooncology. 2019 05; 28(5):1033-1040.
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Partridge AH, Ruddy KJ, Barry WT, Greaney ML, Ligibel JA, Sprunck-Harrild KM, Rosenberg SM, Baker EL, Hoverman JR, Emmons KM. A randomized study to improve care for young women with breast cancer at community and academic medical oncology practices in the United States: The Young and Strong study. Cancer. 2019 06 01; 125(11):1799-1806.
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Hubbeling HG, Rosenberg SM, González-Robledo MC, Cohn JG, Villarreal-Garza C, Partridge AH, Knaul FM. Psychosocial needs of young breast cancer survivors in Mexico City, Mexico. PLoS One. 2018; 13(5):e0197931.
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Rosenberg SM, Greaney ML, Patenaude AF, Sepucha KR, Meyer ME, Partridge AH. "I don't want to take chances.": A qualitative exploration of surgical decision making in young breast cancer survivors. Psychooncology. 2018 06; 27(6):1524-1529.
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Park EM, Gelber S, Rosenberg SM, Seah DSE, Schapira L, Come SE, Partridge AH. Anxiety and Depression in Young Women With Metastatic Breast Cancer: A Cross-Sectional Study. Psychosomatics. 2018 May - Jun; 59(3):251-258.
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Rosenberg SM, Gelber S, Gelber RD, Krop E, Korde LA, Pagani O, Partridge AH. Oncology Physicians' Perspectives on Practices and Barriers to Fertility Preservation and the Feasibility of a Prospective Study of Pregnancy After Breast Cancer. J Adolesc Young Adult Oncol. 2017 Sep; 6(3):429-434.
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Rosenberg SM, Partridge AH. Looking back, moving forward: the evolution of cancer survivorship care. Lancet Oncol. 2017 01; 18(1):18-19.
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Rosenberg SM, King TA. Contralateral prophylactic mastectomy and quality of life: answering the unanswered questions? Gland Surg. 2016 Jun; 5(3):261-2.
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Rosenberg SM, Ruddy KJ, Tamimi RM, Gelber S, Schapira L, Come S, Borges VF, Larsen B, Garber JE, Partridge AH. BRCA1 and BRCA2 Mutation Testing in Young Women With Breast Cancer. JAMA Oncol. 2016 Jun 01; 2(6):730-6.
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Walker HE, Rosenberg SM, Stanton AL, Petrie KJ, Partridge AH. Perceptions, Attributions, and Emotions Toward Endocrine Therapy in Young Women with Breast Cancer. J Adolesc Young Adult Oncol. 2016 Mar; 5(1):16-23.
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Rosenberg SM, Partridge AH. Management of breast cancer in very young women. Breast. 2015 Nov; 24 Suppl 2:S154-8.
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Rosenberg SM, Newman LA, Partridge AH. Breast Cancer in Young Women: Rare Disease or Public Health Problem? JAMA Oncol. 2015 Oct; 1(7):877-8.
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Rosenberg SM, Partridge AH. New Insights Into Nonadherence With Adjuvant Endocrine Therapy Among Young Women With Breast Cancer. J Natl Cancer Inst. 2015 Oct; 107(10).
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Rosenberg SM, Moskowitz CS, Ford JS, Henderson TO, Frazier AL, Diller LR, Hudson MM, Stanton AL, Chou JF, Smith S, Leisenring WM, Mertens AC, Cox CL, Nathan PC, Krull KR, Robison LL, Oeffinger KC. Health care utilization, lifestyle, and emotional factors and mammography practices in the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev. 2015 Nov; 24(11):1699-706.
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Rosenberg SM, Sepucha K, Ruddy KJ, Tamimi RM, Gelber S, Meyer ME, Schapira L, Come SE, Borges VF, Golshan M, Winer EP, Partridge AH. Local Therapy Decision-Making and Contralateral Prophylactic Mastectomy in Young Women with Early-Stage Breast Cancer. Ann Surg Oncol. 2015 Nov; 22(12):3809-15.
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Rosenberg SM, Stanton AL, Petrie KJ, Partridge AH. Symptoms and Symptom Attribution Among Women on Endocrine Therapy for Breast Cancer. Oncologist. 2015 Jun; 20(6):598-604.
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Borstelmann NA, Rosenberg SM, Ruddy KJ, Tamimi RM, Gelber S, Schapira L, Come S, Borges V, Morgan E, Partridge AH. Partner support and anxiety in young women with breast cancer. Psychooncology. 2015 Dec; 24(12):1679-85.
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Rosenberg SM, Partridge AH. Contralateral Prophylactic Mastectomy: An Opportunity for Shared Decision Making. JAMA Surg. 2014 Jun; 149(6):589-90.
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Rosenberg SM, Tamimi RM, Gelber S, Ruddy KJ, Bober SL, Kereakoglow S, Borges VF, Come SE, Schapira L, Partridge AH. Treatment-related amenorrhea and sexual functioning in young breast cancer survivors. Cancer. 2014 Aug 01; 120(15):2264-71.
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Rosenberg SM, Tracy MS, Meyer ME, Sepucha K, Gelber S, Hirshfield-Bartek J, Troyan S, Morrow M, Schapira L, Come SE, Winer EP, Partridge AH. Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey. Ann Intern Med. 2013 Sep 17; 159(6):373-81.
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Tracy MS, Rosenberg SM, Dominici L, Partridge AH. Contralateral prophylactic mastectomy in women with breast cancer: trends, predictors, and areas for future research. Breast Cancer Res Treat. 2013 Aug; 140(3):447-52.
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Rosenberg SM, Partridge AH. Premature menopause in young breast cancer: effects on quality of life and treatment interventions. J Thorac Dis. 2013 Jun; 5 Suppl 1:S55-61.
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Frazier AL, Rosenberg SM. Preadolescent and adolescent risk factors for benign breast disease. J Adolesc Health. 2013 May; 52(5 Suppl):S36-40.
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Rosenberg SM, Tamimi RM, Gelber S, Ruddy KJ, Kereakoglow S, Borges VF, Come SE, Schapira L, Winer EP, Partridge AH. Body image in recently diagnosed young women with early breast cancer. Psychooncology. 2013 Aug; 22(8):1849-55.
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