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Xiaole Shirley Liu, PhD


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Xiaole Shirley Liu, PhD


  • Director, Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute
  • Professor of Biostatistics and Computational Biology, Harvard T.H. Chan School of Public Health

Contact Information

  • Office Phone Number(617) 632-2472
  • Fax(617) 632-2444


Dr. X. Shirley Liu graduated summa cum laude from Smith College double majoring in Biochemistry and Computer Science in 1997, and received PhD in Biomedical Informatics and PhD minor in Computer Science from Stanford University in 2002. She is now Professor at the Department of Biostatistics and Computational Biology at the Dana-Farber Cancer Institute and Harvard School of Public Health. She is the Director of the Center of Functional Cancer Epigenetics at Dana-Farber Cancer Institute, and an associate member of the Broad Institute. Her research focuses on computational cancer epigenetics, and developing algorithms for big cancer data integration and mining. 

Recent Awards:

  • Claudia Adams Barr Award for Innovative Basic Cancer Research 2005
  • Department of Defense Prostate Cancer Research Program New Investigator Award 2006
  • Sloan Research Fellowship 2008


Computational Cancer Epigenetics

Through genome-wide transcription factor binding, chromatin dynamics, and gene expression profiles, we try to model the specificity and function of transcription factors, chromatin regulators and lncRNAs in tumor development, progression, drug response and resistance. 

Research Departments:

Research Website:


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