Stem Cell Transplant Outcomes
Our 1-year survival rates exceed those of other stem cell transplant programs. Based on data from 182 patients who had their first allogeneic transplant (cells from a related or unrelated donor/cord blood) during 2015, 2016, and 2017, the 1-year survival
of these patients is 89.3%, compared to similar patients transplanted at other U.S. programs, where the rate ranged from 77.9% - 88.2%.
Our state-of-the-art stem cell transplant facility is designed specifically for children and young adults undergoing hematopoietic cell transplant — minimizing their exposure to harmful toxins and germs without preventing their freedom to leave their
room or interact with family and friends.
Our Collaborative Approach
Our Pediatric Stem Cell Transplant Program works closely with clinicians and caregivers from multiple specialties including Pulmonology, Radiology, Infectious Disease, Metabolism, Nephrology, Pathology, Radiation Oncology, Cardiology, Surgery, and the
Intensive Care Unit.
In addition, we collaborate with several national research groups, including the Children's Oncology Group, Blood and Marrow Transplant Clinical Trials Network, and the Pediatric Blood and Marrow Transplant Consortium to develop innovative clinical trials
and expand transplantation for new conditions. We have an active stem cell research program that includes scientists who partner with our clinical care team to improve outcomes for hematopoietic stem cell transplantation.
Our research program includes many stem cell transplant clinical trials. These studies are pushing promising techniques and therapies forward. Your child may be eligible to participate in a clinical trial as part of treatment. Your care team will discuss
your child's treatment plan at length with you, including any clinical trial options available.
View pediatric stem cell clinical trials.
Learn more about pediatric stem cell research at Boston Children's Hospital.
Specially-Trained Donor Search Coordinator
When your child is undergoing an unrelated donor transplant, our pediatric-specific donor search coordinator will help your child's physician identify the best possible donor. Once a suitable donor has been found, the donor search coordinator will work
with your care team, the donor registry, and donor center to schedule the stem cell harvest. Our donor services program has a National Marrow Donor Program (NMDP) accreditation to coordinate donor searches for patients.
Learn more about Finding a Stem Cell Donor for Your Child.
Stem Cell Transplant Accreditations
For more than a decade, our Stem Cell Transplant Program has been accredited by the Foundation for the Accreditation of Cellular Therapy. In addition, our Program is fully accredited by the National Marrow Donor Program;
we are a charter member of the Blood and Marrow Transplant Clinical Trials Network of the National Institutes of Health; and a member of both the Center for International Blood and Marrow Transplant Research,
and the Cancer and Leukemia Group B.
Dedicated Good Manufacturing Practice (GMP) Facility
A GMP facility adheres to specific manufacturing processes and practices established by the U.S. Food and Drug Administration. Dana-Farber Cancer Institute is home to the Connell and O'Reilly Families Cell Manipulation Core Facility — New England's
only Class 10,000 GMP cell therapy facility and academic medical center.
Quality Initiatives for Stem Cell Transplantation
Dana-Farber's Department of Cellular Therapy Quality Assurance is devoted to overseeing quality improvement, quality assurance,
and quality control issues involving stem cells and all other cellular products used for patients.