Pediatric Stem Cell Transplant Program

Stem cell transplant (or bone marrow transplant) is used to treat many types of conditions affecting children and young adults. While traditionally used to treat cancers and blood disorders, hematopoietic cell transplants are increasingly being used to treat a growing range of conditions, including metabolic diseases, genetic immunodeficiencies and other disorders.

At Dana-Farber/Boston Children's Cancer and Blood Disorders Center, stem cell transplant may be used to treat the following conditions:

Blood Disorders

• Aplastic anemia
• Congenital sideroblastic anemia
• Dyskeratosis congenita
• Fanconi anemia
• Myelodysplastic syndrome
• Sickle cell disease
• Thalassemia

Cancers

• Acute lymphoblastic leukemia (ALL) — including relapsed ALL
• Acute myelogenous leukemia (AML)
• Brain tumors
• Chronic myelogenous leukemia
• Hodgkin lymphoma
• Juvenile myelomonocytic leukemia (JMML)
• Non-Hodgkin lymphoma
• Solid tumors such as neuroblastoma and Wilms' tumor

Genetic Immunodeficiencies

• Chronic granulomatous disease (CGD)
• Combined variable immunodeficiency (CVID)
• Hemophagocytic lymphohistiocytosis (HLH)
• X-linked lymphoproliferative disease (XLP)
• X-linked severe combined immunodeficiency 1 (SCID-X1)
• Wiskott Aldrich Syndrome (WAS)

Metabolic Diseases

• Adrenoleukodystrophy (ALD)
• Globoid cell leukodystrophy (Krabbe disease)
• Hunter syndrome
• Hurler syndrome
• Metachromatic leukodystrophy
• Morquio syndrome
• Sanfilippo syndrome

Osteopetrosis