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Status: RecruitingPhase: Phase 2Diagnosis: Pediatric Hodgkin LymphomaNCT ID: NCT00846742
(View complete trial on ClinicalTrials.gov)
DFCI Protocol ID: 09-273
This phase II trial is studying how well combination chemotherapy with or without radiation therapy works in treating young patients with favorable-risk Hodgkin lymphoma. Drugs used in chemotherapy, such as doxorubicin hydrochloride, vinblastine, mechlorethamine hydrochloride, vincristine sulfate, bleomycin, etoposide, and prednisone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. Radiation therapy uses high-energy x-rays to kill cancer cells for those patients that still had residual cancer at the end of chemotherapy. Giving combination chemotherapy with radiation therapy may kill more cancer cells and allow doctors to save the part of the body where the cancer started.
Conducting Institutions: Massachusetts General Hospital, Dana-Farber Cancer Institute, Children's Hospital Boston
Overall PI: Alison Friedmann, MD,
Massachusetts General Hospital
Site-responsible Investigators: Amy Billett, MD,
Dana-Farber Cancer Institute
Contacts: Massachusetts General Hospital:
Cancer Trials Call Center, 877-789-6100Dana-Farber Cancer Institute:
Childrens Hospital Pediatric Clinical Translation Investigation Program CTIP,