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Study of Kidney Tumors in Younger Patients

Status: Recruiting
Phase: N/A
Diagnosis: Pediatric Kidney Tumor, Pediatric Wilms' Tumor
NCT ID: NCT00898365 (View complete trial on
DFCI Protocol ID: 06-159


This laboratory study is looking at kidney tumors in young patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer. It may also help the study of cancer in the future.


Conducting Institutions:
Dana-Farber Cancer Institute, Massachusetts General Hospital, Children's Hospital Boston

Overall PI:
Elizabeth Mullen, MD, Dana-Farber Cancer Institute

Site-responsible Investigators:
Mary Huang, MD, Massachusetts General Hospital

Dana-Farber Cancer Institute: Childrens Hospital Pediatric Clinical Translation Investigation Program CTIP,
Massachusetts General Hospital: Cancer Trials Call Center, 877-789-6100

Eligibility Criteria

DISEASE CHARACTERISTICS: - Diagnosis of renal tumors, including any of the following: - Nephroblastic tumors - Nephroblastoma (Wilms' tumor) (favorable histology, anaplasia [diffuse, focal]) - Nephrogenic rests and nephroblastomatosis - Cystic nephroma and cystic partially differentiated nephroblastoma - Metanephric tumors (metanephric adenoma, metanephric adenofibroma, metanephric stromal tumor) - Mesoblastic nephroma (cellular, classic, mixed) - Clear cell sarcoma - Rhabdoid tumor (any malignant rhabdoid tumor occurring outside the CNS) - Renal epithelioid tumors of childhood (papillary renal cell carcinoma, medullary renal cell carcinoma, renal tumors associated with Xp11.2 translocations, oncocytic renal neoplasms after neuroblastoma) - Angiolipoma - Ossifying renal tumor of infancy - Paraffin-embedded tumor samples requested and available - Blood samples available - Urine samples requested and available - Copies of imaging studies available PATIENT CHARACTERISTICS: - Not specified PRIOR CONCURRENT THERAPY: - No prior therapy for cancer
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