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Status: RecruitingPhase: Phase 1Diagnosis: Leukemia/MDSNCT ID: NCT02081378
(View complete trial on ClinicalTrials.gov)
DFCI Protocol ID: 14-117
The design of a phase I, open label, dose finding study was chosen in order to establish a safe and tolerated dose of single agent ABL001 in CML and Ph+ ALL patients who are relapsed or refractory to or are intolerant of TKIs, and of ABL001+Nilotinib, ABL001+Imatinib and ABL001+Dasatinib in Ph positive CML patients who are relapsed or refractory to TKIs.
Conducting Institutions: Dana-Farber Cancer Institute, Brigham and Women's Hospital
Overall PI: Daniel DeAngelo, MD,
Dana-Farber Cancer Institute
Contacts: Dana-Farber Cancer Institute:
Ilene Galinsky, 617-632-3902,