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CCG performs a variety of genomics assays, from targeted hybrid capture to whole-genome DNA sequencing, RNA sequencing, and single-cell sequencing on a multitude of sample types (e.g., fresh-, frozen-, and FFPE-derived nucleic acids).
In addition to our standard suite of services, CCG often takes part in collaborations to develop and evaluate new NGS assays and techniques. As part of this process, we work with investigators in forging a research and development proposal and can assist
in all aspects of research, including procurement of funding (e.g., grant submissions).
Liquid biopsies represent a readily accessible sample type upon which molecular profiling with NGS can be performed. CCG has worked with several investigators to develop library construction and hybrid capture assays tailored to the needs of cfDNA. All of our library adapters consist of unique, dual-matched barcodes containing a unique molecular identifier (UMI) which allow us to:
CCG offers both poly-A enrichment and ribodepletion workflows, which are fully automated. We are continuously improving our library construction techniques on FFPE samples and will be designing
custom hybrid capture bait sets that will target both messenger RNA and fusion transcripts resulting from genomic rearrangements:
Our Innovation Lab has extensive experience with various single cell technologies. CCG performs both single-cell RNAseq (scRNAseq) and single-nucleus RNAseq (snRNAseq) on fresh and frozen tissue samples, respectively. Our workflows include:
Our teams of Pathology Technicians and Project Managers can help optimize sample collection and project management for your study.
CCG Associate Director: Aaron ThornerDCBC Biopsy Collections: Karla HelvieBioinformatics: Tony Anselmo
For general questions:617-582-7253 email@example.com