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The Center for Neuro-Oncology offers state-of the-art treatment for patients with brain tumors, spinal cord tumors, and neurologic complications from cancer. Our specialists work to ensure you receive coordinated treatment and support. We focus on helping you cope with your illness and maintain the quality of your life.
The Center for Neuro-Oncology offers the latest advances in care for adult patients with tumors of the brain or spinal cord, as well as for neurologic complications of cancer and its treatments. Treatment for brain cancer is complex and treatment planning requires involvement from many subspecialists including neurosurgeons, radiation oncologists and medical oncologists. Through our Multidisciplinary Clinic, patients have the benefit of meeting with our team of surgical, medical, and radiation oncologists at one time and in one place to develop individualized treatment plans.
We focus on treating both common and rare brain tumors, including glioma, glioblastoma, oligodendroglioma, astrocytoma, meningioma, lymphoma, brain metastases, and medulloblastoma.
Learn how we diagnose and treat brain tumors
Learn about our Brain Metastases Program
Learn about our Spinal Tumor Program
Our clinicians are experts in treatment options that include precise neurosurgical techniques, radiation therapy that targets tumors while sparing surrounding tissues, and a variety of chemotherapy and molecular drugs targeting your type of cancer.
You may also benefit from our research program. As we search for new, more effective treatments, we are able to offer our patients access to a range of clinical trials for various types and stages of brain and spinal cord cancers.
Our research is dedicated to advancing brain tumor diagnosis and treatment. Learn more about our research and treatment in the key areas of immunotherapy, cancer genetics/genotyping, and targeted therapies/precision cancer medicine.
Our approach to compassionate care centers on the individual needs of our patients and their families. Our team members work closely together to ensure that you receive carefully coordinated treatment and support. We focus on helping you cope with your illness and maintain the quality of your life.
You and your family are key members of the care team. While we understand your illness, you understand your own body. We welcome your questions and value your participation as we make decisions together.
Approximately 23,000 new cases of malignant brain and spinal cord tumors are diagnosed in the U.S. each year. Learn about the different types of brain tumors, signs and symptoms, and treatment options.
View this Slideshare presentation by Patrick Wen, MD, director of Dana-Farber's Center for Neuro-Oncology,in which he discusses how molecular testing can help guide treatment decisions for patients with glioblastoma, meningioma, medulloblastoma, and other brain tumors. The presentation was originally given as a webinar hosted by the American Brain Tumor Association.
View this Slideshare presentation by Patrick Wen, MD, director of Dana-Farber's Center for Neuro-Oncology,in which he presents the latest treatment options and research for brain tumor patients.
View this Slideshare presentation by Dana-Farber nutritionist Emily Biever, MS, RD, LDN, in which she discusses healthy eating tips for brain tumor patients. Learn about diets, food fads, and healthy recipes.
View this Slideshare presentation by Dana-Farber neuropsychologist Clare Humphreys, PhD, in which she discusses the mental difficulties that brain tumor patients face, and how to cope with symptoms of treatment.
Read our Insight blog for information and inspiration about Dana-Farber care and research for brain tumors.
Treatment for brain cancers is complex, and treatment planning requires involvement and coordination among many subspecialists. That's why we take a multidisciplinary approach to developing a comprehensive treatment plan tailored to your type of cancer. Through our multidisciplinary clinic, you meet with a team of specialists, as a group, to develop an individualized treatment plan that works for your needs. The multidisciplinary team involved in coordination of your care includes specialists in:
We understand that cancer affects patients and their families in many ways. In addition to clinical care, we offer a wide range of support services to help you and your family manage your experience with cancer treatment and survivorship, including:
Depending on your diagnosis, your team may include the following specialists:
Rameen Beroukhim, MD, PhDEudocia Quant Lee, MD, MPHLakshmi Nayak, MDDavid A. Reardon, MDMikael Rinne MD, PhDPatrick Wen, MD
Lisa Doherty, APRN, OCNDebra Conrad LaFrankie, RN, OCNJennifer Stefanik, NPSandra French Ruland, RN
Ayal Aizer, MD, MHSBrian Alexander, MD, MPHKaren Marcus, MDShyam Tanguturi, MD
Shelly Lynn Beckley, NP
Sheila Connelly, RN
Rachel Silverman, RN
Osama Al-Mefty, MDMohammed Aziz-Sultan, MDJohn Chi, MD, MPHEnnio A. Chiocca, MD, PhDElizabeth Claus, MD, PhDRose Du, MD, PhDIan Dunn, MDKai Frerichs, MDAlexandra Golby, MDWilliam B. Gormley, MDMichael W. Groff, MDEdward Laws, MDPier Paolo Peruzzi, MD, PhDTimothy R. Smith. MD, PhD, MPH
Sara June Dagen, RN
Sherry Iuliano, FNP-C
Mary Beth Mondello, NP
Daniel Triggs, NP
Umberto De Girolami, MDMel Feany, MD, PhDHart Lidov, MDKeith Ligon, MD, PhDSandro Santagata, MD, PhD
Clare Humphreys, PhD
Rachel Allende,LICSW (Spanish and Portuguese-speaking patients)
Sara E. Nemitz, LICSW (inpatient)
Nancy Goldsmith Tharler, LICSW
The Center for Neuro-Oncology is at the forefront of discovery and development of new treatments for brain and central nervous system tumors. Center investigators have made important inroads in basic and clinical research to better understand the biology that underlies these tumors and identify and test new therapies.
Our researchers are also involved in many projects for the Dana-Farber/Harvard Cancer Center Brain Cancer SPORE (Specialized Program of Research Excellence), including those focused on PI3K inhibitors, IDH mutations, Olig2 suppressors and immunotherapy.
Our Center offers a number of exciting clinical trials for patients with primary and metastatic brain and spinal cord tumors. These trials explore several innovative approaches to improve outcomes and quality of life for brain tumor patients, including immunotherapy, targeted therapies, and anti-angiogenesis inhibitors.
Learn more about our clinical trials:
Our research team is leading basic, translational and clinical research aimed at advancing the understanding, diagnosis, and treatment of brain tumors. Areas of focus include:
In addition, we are conducting research on CNS and systemic lymphoma, brain metastasis, adaptive designs for brain tumor clinical trials, neurologic complications of cancer, oncolytic viruses, surgical brain mapping, molecular and cellular surgical oncology, CNS drug delivery/mass spectometry, preclinical animal models, tumor metabolism/IDH mutations, Olig 2 suppression, and advanced neuro-imaging.
Patrick Wen, MD
Focus: Targeted therapiesPub Med
David Reardon, MD
Focus: ImmunotherapyPub Med
Ennio Chiocca, MD, PhD
Focus: Novel experimental therapies for malignant brain tumorsChiocca LabPub Med
Brian Alexander, MD, MPHPub Med
Nathalie Agar, PhD
Focus: Molecular diagnosis and prognosis for clinical and surgical applicationsSurgical Molecular Imaging LabPub Med
Rameen Beroukhim, MD, PhDPub Med
Alexandra Golby, MD
Focus: Structural and functional MRI and brain electrophysiologySurgical Brain Mapping LabPub Med
Raymond Huang, MD, PhD
Focus: Advanced neuro-imagingPub Med
Mark Johnson, MD, PhD
Focus: Mechanisms underlying brain tumor developmentThe Johnson LaboratoryPub Med
William Kaelin, Jr., MD
Focus: Targeted therapies and precision cancer medicineKaelin LabPub Med
Eudocia Lee, MD, MPHPub Med
Keith Ligon, MD, PhD
Focus: Genotyping and neuropathologyLigon LabPub Med
Srinivasan Mukundan, Jr. MD, PhD
Focus: Advanced neuro-imagingPub Med
Andrew Norden, MD, MPHPub Med
Thomas Roberts, PhD
Focus: Targeted therapies and precision cancer medicine Pub Med
Sandro Santagata, MD, PhD
Focus: Neuro-pathologyPub Med
Charles Stiles, PhD
Focus: Olig-2 suppressionPub Med
Read our Insight blog for information and inspiration about Dana-Farber brain tumor research.
If you have never been seen before at Dana-Farber/Brigham and Women's Cancer Center, please call 877-442-3324 or use our online form to request an appointment.
You may schedule your first appointment for as soon as the next day. After scheduling, one of our nurses will call you to answer your questions and help you prepare for the appointment.
For all other inquiries, please call 617-632-2166.
Radiation Oncology: 617-732-6313, option 3
Referring physicians: 617-632-3703