• Sarcoma and Bone Cancer Treatment Center

    Dana-Farber/Brigham and Women's Cancer Care

    Patients with sarcoma often require a combination of surgery, chemotherapy, and radiation therapy. We recognize that a team approach is the best way to manage these complicated cases. Our group is dedicated to clinical research to develop cutting-edge treatment strategies for both soft tissue and bone malignancies.

    About the Center

    sarcoma doctor with a patient

    The Center for Sarcoma and Bone Oncology has dedicated specialty expertise in the pathologic and radiologic assessment of sarcoma, the application of novel soft-tissue and bone reconstructive techniques, and access to promising new therapies.

    Patients with sarcoma often require a combination of surgery, chemotherapy, and radiation therapy. We recognize that a team approach to treatment is the best way to manage these complicated cases.

    Our specialists focus exclusively on sarcoma and work closely together to offer these services in a coordinated manner.

    Our group is also dedicated to clinical research to help identify and develop cutting-edge treatment strategies for both soft tissue sarcomas and bone malignancies such as osteosarcoma, resulting in reduced recurrence rates and improved outcomes for patients.

    Our specialists see patients with all types of sarcoma and a variety of mesenchymal tumors, including: 

    • Alveolar soft part sarcoma
    • Angiomatoid fibrous histiocytoma
    • Angiosarcoma 
    • Atypical lipomataous tumor
    • Bone cancer 
    • Chondrosarcoma 
    • Clear cell sarcoma (malignant melanoma of soft parts)
    • Dendritic cell sarcoma
    • Dermatofibrosarcoma protuberans
    • Desmoid tumor 
    • Desmoplastic small cell tumor
    • Desmoplastic small round cell tumors
    • Ectomesenchymoma
    • Endometrial sarcoma 
    • Epithelioid sarcoma 
    • Ewing sarcoma 
    • Extrarenal rhabdoid tumor
    • Extraskeletal mesenchymal chondrosarcoma
    • Extraskeletal myxoid chondrosarcoma
    • Extraskeletal osteosarcoma
    • Fibromyxoid sarcoma
    • Fibrous histiocytoma of bone
    • Fibrosarcoma 
    • Gastrointestinal stromal tumor (GIST) 
    • Granulation cell sarcoma
    • Hemangioendothelioma
    • Hemangiopericytoma
    • Inflammatory myofibroblastic tumor
    • Intimal sarcoma
    • Kaposi sarcoma 
    • Leiomyosarcoma 
    • Lipoma
    • Liposarcoma
    • Lymphoangiosarcoma
    • Malignant fibrous histiocytoma (MFH)
    • Malignant glomus tumor
    • Malignant granular cell tumor
    • Malignant melanotic schwannoma
    • Malignant mesenchymoma
    • Malignant peripheral nerve sheath tumor
    • Malignant primative neuroectodermal tumor (PNET)
    • Malignant schwannoma
    • Malignant tenosynovial giant cell tumor
    • Myoepithelioma/mixed tumor of soft tissue
    • Myofibroblastic sarcoma
    • Myxofibrosarcoma
    • Myxoinflammatory fibroblastic sarcoma
    • Neurofibrosarcoma 
    • Osteoganic sarcoma
    • Osteosarcoma 
    • PEComa
    • Radiation associated sarcomas
    • Rhabdomyosarcoma
    • Soft tissue sarcoma 
    • Solitary fibrous tumor
    • Spindle cell sarcoma
    • Synovial sarcoma 
    • Undifferentiated pleomorphic sarcoma
    • Undifferentiated sarcoma
    • Unclassified sarcoma
    • Uterine sarcoma 

    Our Treatment Approach

    When you come to Dana-Farber Cancer Institute for sarcoma treatment, you will meet with members of our team who have specialized expertise in caring for patients with sarcoma.

    This means pathologists, medical oncologists, radiologists, surgeons and other health care professionals with expertise in sarcoma may be involved in important decisions about your care.

    Learn about our multidisciplinary approach to sarcoma treatment 

    When our pathologists confirm a sarcoma diagnosis, our clinicians meet to discuss next steps. The treatment plan is tailored, as much as possible, to each individual patient and their disease profile, taking into account such details as the patient's age, prior medical conditions, lifestyle and personal preferences.

    Learn about the role of pathology in sarcoma diagnosis and treatment 

    If the sarcoma is localized — if it has not spread to other parts of the body — the goal is to cure the patient. This could involve surgery and radiation, with chemotherapy also used in certain types of sarcoma. It is important to involve an experienced sarcoma surgeon in treatment decisions.

    Learn about the role of the surgical oncologist in sarcoma treatment 

    If the sarcoma is advanced, or metastatic, the goal is to give the patient as high a quality of life as possible for as long as possible, and cure in some cases. This may involve some surgery, chemotherapy or radiation therapy, and observation. We will also ensure access to the highest quality clinical research and new drugs available for the treatment of sarcomas.

    Learn about the role of the medical oncologist in sarcoma treatment 

    The treatment team at Dana-Farber's sarcoma treatment center consists of more than just physicians. During your treatment, you may also meet and work with many of our vital support team members, including:

    • Nurse Practitioners, who focus on treatment-related symptom management, sarcoma education, and home support
    • Physician assistants, who assist the surgical oncologist in clinic and care, wound management, and post-surgical symptom management
    • Infusion nurses, who administer chemotherapy and focus on symptom management
    • Radiation oncology nurses, who evaluate and monitor patients undergoing radiation treatment
    • Clinical research coordinators, who coordinate appointments for patients enrolled in clinical trials
    • Research nurses, who provide information on clinical trials and are part of the team for all patients enrolled in clinical trials
    • Palliative care specialists, who help patients manage pain and the side effects of cancer treatment
    • Social workers, who provide emotional support to patients and families during diagnosis, treatment, and beyond

    Our team can also help you find other support services within Dana-Farber, including nutrition, complementary therapies, spiritual support, financial help, survivorship and resources for families and young adults.

    The Treatment Team

    Because patients with sarcoma often require a combination of treatment methods, we approach the care of each patient as a team.

    Medical Oncology

    James Butrynski, MD
    George D. Demetri, MD
    Suzanne George, MD
    Jeffrey Morgan, MD
    Andrew Wagner, MD, PhD 

    Sarcoma Nursing

    Melissa Hohos, RN
    Margaret Loucks, NP
    Mark Morley, RN
    Kathy Polson, NP
    Julie Shelly, RN

    Surgical Oncology

    Monica Bertagnolli, MD
    Chandrajit Raut, MD
    Jiping Wang, MD
    Michelle Lapidus, PA

    Orthopedic Oncology

    John Ready, MD
    Marco Ferrone, MD
    Andrea Milligan, PA
    Susanna Santos, PA

    Radiation Oncology

    Elizabeth Baldini, MD
    Phillip M. Devlin, MD, FACR
    Karen Marcus, MD 

    Pediatric Oncology

    Holcombe Grier, MD
    Carlos Rodriguez-Galindo, MD
    Katherine A. Janeway, MD 

    Plastic and Reconstructive Surgery

    Dennis Orgill, MD
    Julian Pribaz, MD
    Bohdan Pomahac, MD
    Lifei Guo, MD, PhD 


    Christopher D.M. Fletcher, MD
    Jason L. Hornick, MD, PhD
    Jonathan A. Fletcher, MD 

    Radiology and Imaging

    Annick van den Abbeele, MD 

    Social Work

    Rachel Allende, LICSW (Spanish and Portuguese-speaking patients)
    Larissa Hewitt, LICSW
    Katelyn Uyehara, LCSW (Inpatient)

    We also work in close collaboration with our colleagues in the Head and Neck Oncology Program and the Thoracic Oncology Program.

    Contact Information

    New Patients

    If you have never been seen before at Dana-Farber/Brigham and Women's Cancer Center, please call 877-442-3324 or use this online form to make an appointment. For all other inquiries, please call 617-632-5204.

    Pediatric patients should call Dana-Farber/Children's Hospital Cancer Center at 888-PEDI ONC (733-4662).

    Established Patients

    If you are already a patient in the Center for Sarcoma and Bone Oncology, please call 617-632-5204.

    Referring Physicians

    If you would like to refer a patient, please call 617-632-5204, and select option 1. You can also send a fax to 617-632-3408.

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  • Make an Appointment

    • For adults:
      877-442-3324 (877-442-DFCI)
    • For children:
      888-733-4662 (888-PEDI-ONC)
    • Or complete the online form.
  • What Is Sarcoma?

    • Dr. George DemetriIn this video, Dr. George Demetri explains what sarcoma is and how it is treated.
  • Join Our Sarcoma Online Community

    • Share your story, learn from others, and draw support in the CancerConnect Sarcoma Online Community.
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