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Adult Leukemia Program Clinical Research and Trials

  • The clinical research mission of the Adult Leukemia Program is to develop and bring new and better therapies to patients. At any given time, the program offers patients a wide array of opportunities to participate in clinical research studies relating to all stages and types of leukemia and related disorders.

    Patients have access to trials that originate within Dana-Farber/Brigham and Women's Cancer Center and other Harvard-affiliated institutions, those sponsored by private industry, as well as those that are part of a collaborative effort, such as the Cancer and Leukemia Group B, of which the program is a member.

    Physician-researchers within the program are currently involved in a number of exciting avenues of investigation, which include targeted therapies aimed at making cancer treatment more specific and less toxic. These include:

    • immunotherapy for acute leukemia and myelodysplasia involving agents such as interleukin-2 and autologous vaccines
    • integrating antibody-based therapy against leukemia cells with standard chemotherapy
    • promoting the differentiation or normal growth of bone marrow cells in patients with myelodysplasia
    • working with molecules that interrupt the normal cascade of biochemical signals within the cell that promote the growth of leukemia

    Other innovative offerings include treating adults with acute lymphoblastic leukemia by applying the principles used in successful pediatric treatments of this condition and clinical trials and treatments specialized for older adults.

    See current clinical trials for leukemia and myelodysplastic syndromes at Dana-Farber


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  • Research for MDS
    David Steensma, MD, leads clinical care for patients with myelodysplastic syndromes (MDS) at Dana-Farber. Watch as he discusses basic, clinical, and population science studies underway at Dana-Farber that aim to develop more effective therapies and improve quality of life for patients with MDS.