A. Lindsay Frazier, MD

A. Lindsay Frazier, MD

Pediatric Hematology/Oncology

Contact Information

Fax

617-632-5710

Appointments

617-632-3270 (Established Pediatric Patients)
888-733-4662 (New Pediatric Patients)

Biography

A. Lindsay Frazier, MD

Dr. Frazier received her MD from Dartmouth Medical School in 1984, followed by a pediatric residency at Children’s Hospital Boston and a pediatric hematology-oncology fellowship at DFCI, where she joined the faculty in 1990. She received an ScM from Harvard School of Public Health in 1993. In clinical practice, she concentrates on germ cell tumors, while her epidemiologic research primarily focuses on colorectal cancer screening and prevention.

Researcher

Physician

Institute Physician
Professor of Pediatrics, Harvard Medical School
Associate Professor of Epidemiology, Harvard T.H. Chan School of Public Health

Centers/Programs

Clinical Interests

Cancer epidemiology, Cancer prevention in children, Germ cell tumors, Global health

Board Certification

  • Pediatric Hematology/Oncology
  • Pediatrics

Fellowship

  • Boston Children's Hospital/Dana-Farber Cancer Institute, Pediatric Hematology/Oncology

Residency

  • Boston Children's Hospital, Pediatrics

Medical School

  • Dartmouth Medical School

Recent Awards

  • Boston Combined Residency Program Faculty Teaching Honor Roll, 2017-2018

Research

    Cancer Prevention in Adolescents, Colorectal Screening, Germ Cell Tumors

    Our research focuses on three main areas: (1) adolescent behaviors that predispose to adult malignancy (e.g., diet, tobacco and alcohol consumption, and level of physical activity); (2) prevention policies for both primary and secondary cancer; and (3) treatment of germ cell tumors in pediatric patients. Three cohort studies serve as the basis for this research: Nurses' Health Study I (NHS I), Nurses' Health Study II (NHS II), and the Growing Up Today Study (GUTS). In analyzing tobacco use among the 16,600 children who participate in GUTS, we have focused on identifying factors that predispose children to progress through the stages of tobacco uptake: abstainer, contemplator, experimenter, occasional user, regular user, and addicted user. We found that increased risk of cigarette use was due to excessive weight concerns, willingness to use tobacco promotional items, use of cigars, and low self-esteem. Among women in the NHS I, we have investigated the relation between alcohol use during adolescence, diet during adolescence, and risk of breast cancer. Whereas no effect was demonstrable for alcohol use during adolescence, the null result may reflect only the low level of drinking among this generation of women. However, we found that increased consumption of potatoes, rice, and french fries during adolescence increased risk of breast cancer, as did increased consumption of fish. Refinement of this work is under way via a more extensive adolescent diet questionnaire sent to 60,000 participants of NHS II. We also have completed a cost-effectiveness model of 26 strategies for screening for colorectal cancer, which confirmed that an annual fecal occult blood test with a sigmoidoscopy every 5 years is both effective and cost-effective. Most other strategies recommended recently by a task force of the Agency for Health Care Policy and Research were actually more costly and less effective. The model allows clinicians to examine the tradeoffs between strategies and to tailor recommendations to the patient. In clinical care, Dr. Frazier is the national expert on germ cell tumors in pediatric patients and oversees the care of these patients referred to DFCI. In addition, she is cochair of two national protocols that opened in 1999 for the treatment of low-risk and high-risk pediatric germ cell tumors and chair of the COG Germ Cell subcommittee in COG Rare Tumors.

    Publications

      • Evaluation of prevalence and outcomes of serial tyrosine kinase inhibitor use in pediatric patients with advanced solid tumors. Pediatr Blood Cancer. 2023 Nov; 70(11):e30652. View in: Pubmed

      • Characterizing Lymphovascular Invasion in Pediatric and Adolescent Malignant Ovarian Nongerminomatous Germ Cell Tumors: A Report from the Children's Oncology Group. J Pediatr Surg. 2023 Aug 22. View in: Pubmed

      • Children's Oncology Group's 2023 blueprint for research: Germ cell tumors. Pediatr Blood Cancer. 2023 09; 70 Suppl 6:e30562. View in: Pubmed

      • Refining the serum miR-371a-3p test for viable germ cell tumor detection. Sci Rep. 2023 Jun 29; 13(1):10558. View in: Pubmed

      • Associations between birth defects and childhood and adolescent germ cell tumors according to sex, histologic subtype, and site. Cancer. 2023 10 15; 129(20):3300-3308. View in: Pubmed

      • Adjuvant chemotherapy does not improve outcome in children with ovarian immature teratoma: A comparative analysis of clinical trial data from the Malignant Germ Cell International Consortium. Pediatr Blood Cancer. 2023 Aug; 70(8):e30426. View in: Pubmed

      • Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence. Nat Commun. 2023 05 06; 14(1):2636. View in: Pubmed

      • Loss to follow-up of minorities, adolescents, and young adults on clinical trials: A report from the Children's Oncology Group. Cancer. 2023 05 15; 129(10):1547-1556. View in: Pubmed

      • Exploring Young Adults' Perspectives of Participation in a Mindfulness-Based Music Therapy Intervention Before and During the COVID-19 Pandemic. J Adolesc Young Adult Oncol. 2023 Aug; 12(4):569-576. View in: Pubmed

      • Mobile Source Benzene Regulations and Risk of Childhood and Young Adult Hematologic Cancers in Alaska: A Quasi-experimental Study. Epidemiology. 2023 05 01; 34(3):385-388. View in: Pubmed

      • Unaltered T cell responses to common antigens in individuals with Parkinson's disease. J Neurol Sci. 2023 01 15; 444:120510. View in: Pubmed

      • Evaluation of miR-371a-3p to predict viable germ cell tumor in patients with pure seminoma receiving retroperitoneal lymph node dissection. Andrology. 2023 05; 11(4):634-640. View in: Pubmed

      • Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium. Br J Cancer. 2022 11; 127(9):1577-1583. View in: Pubmed

      • Response to commentary re: Clinicopathologic predictors of outcomes in children with stage I testicular germ cell tumors: A pooled post hoc analysis of trials from the Children's oncology group. J Pediatr Urol. 2022 08; 18(4):513-514. View in: Pubmed

      • Predicted leukocyte telomere length and risk of germ cell tumours. Br J Cancer. 2022 07; 127(2):301-312. View in: Pubmed

      • SIOP Strategy 2021-2025: Cure for more, care for all. Pediatr Blood Cancer. 2022 06; 69(6):e29577. View in: Pubmed

      • Mapping Pediatric Oncology Clinical Trial Collaborative Groups on the Global Stage. JCO Glob Oncol. 2022 02; 8:e2100266. View in: Pubmed

      • Malignant extracranial germ cell tumours: A first national report by the South African Children's Cancer Study Group. Pediatr Blood Cancer. 2022 05; 69(5):e29543. View in: Pubmed

      • Pitfalls in the diagnosis of yolk sac tumor: Lessons from a clinical trial. Pediatr Blood Cancer. 2022 02; 69(2):e29451. View in: Pubmed

      • Childhood cancer drugs in China: An overview and comparison of regulatory approvals in China and the United States. Int J Cancer. 2022 02 01; 150(3):482-490. View in: Pubmed

      • Recommendations for Age-Appropriate Testing, Timing, and Frequency of Audiologic Monitoring During Childhood Cancer Treatment: An International Society of Paediatric Oncology Supportive Care Consensus Report. JAMA Oncol. 2021 Oct 01; 7(10):1550-1558. View in: Pubmed

      • A Multi-institutional Pooled Analysis Demonstrates That Circulating miR-371a-3p Alone is Sufficient for Testicular Malignant Germ Cell Tumor Diagnosis. Clin Genitourin Cancer. 2021 12; 19(6):469-479. View in: Pubmed

      • Pediatric Cancer Data Commons: Federating and Democratizing Data for Childhood Cancer Research. JCO Clin Cancer Inform. 2021 09; 5:1034-1043. View in: Pubmed

      • Juvenile Granulosa Cell Tumor as the Presenting Feature of McCune-Albright Syndrome. J Endocr Soc. 2021 Sep 01; 5(9):bvab098. View in: Pubmed

      • The Road Ahead for Circulating microRNAs in Diagnosis and Management of Testicular Germ Cell Tumors. Mol Diagn Ther. 2021 05; 25(3):269-271. View in: Pubmed

      • Safety of Surgical Fertility Preservation Procedures in Children Prior to Hematopoietic Stem Cell Transplant. Transplant Cell Ther. 2021 08; 27(8):696.e1-696.e4. View in: Pubmed

      • Forecasting essential childhood cancer drug need: An innovative model-based approach. Cancer. 2021 08 15; 127(16):2990-3001. View in: Pubmed

      • Serum Small RNA Sequencing and miR-375 Assay Do Not Identify the Presence of Pure Teratoma at Postchemotherapy Retroperitoneal Lymph Node Dissection. Eur Urol Open Sci. 2021 Apr; 26:83-87. View in: Pubmed

      • Neonatal Malignant Disorders: Germ Cell Tumors. Clin Perinatol. 2021 03; 48(1):147-165. View in: Pubmed

      • The Global COVID-19 Observatory and Resource Center for Childhood Cancer: A response for the pediatric oncology community by SIOP and St. Jude Global. Pediatr Blood Cancer. 2021 05; 68(5):e28962. View in: Pubmed

      • Adolescent and young adult neuro-oncology: a comprehensive review. Neurooncol Pract. 2021 Jun; 8(3):236-246. View in: Pubmed

      • Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection. Science. 2021 02 05; 371(6529). View in: Pubmed

      • Developing and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell Tumors. Methods Mol Biol. 2021; 2195:263-275. View in: Pubmed

      • Adolescent alcohol, nuts, and fiber: combined effects on benign breast disease risk in young women. NPJ Breast Cancer. 2020 Nov 23; 6(1):61. View in: Pubmed

      • Impact of circulating microRNA test (miRNA-371a-3p) on appropriateness of treatment and cost outcomes in patients with Stage I non-seminomatous germ cell tumours. BJU Int. 2021 07; 128(1):57-64. View in: Pubmed

      • International Trends in the Incidence of Cancer Among Adolescents and Young Adults. J Natl Cancer Inst. 2020 11 01; 112(11):1105-1117. View in: Pubmed

      • What are the volume and budget needs to provide chemotherapy to all children with acute lymphoblastic leukaemia in Thailand? Development and application of an estimation tool. BMJ Open. 2020 10 26; 10(10):e041901. View in: Pubmed

      • Outcomes of adolescent males with extracranial metastatic germ cell tumors: A report from the Malignant Germ Cell Tumor International Consortium. Cancer. 2021 01 15; 127(2):193-202. View in: Pubmed

      • Real-World Application of Pre-Orchiectomy miR-371a-3p Test in Testicular Germ Cell Tumor Management. J Urol. 2021 Jan; 205(1):137-144. View in: Pubmed

      • The use of interval-compressed chemotherapy with the addition of vincristine, irinotecan, and temozolomide for pediatric patients with newly diagnosed desmoplastic small round cell tumor. Pediatr Blood Cancer. 2020 10; 67(10):e28559. View in: Pubmed

      • Contemporary management of ovarian germ cell tumors and remaining controversies. Gynecol Oncol. 2020 08; 158(2):467-475. View in: Pubmed

      • Development of a Data Model and Data Commons for Germ Cell Tumors. JCO Clin Cancer Inform. 2020 06; 4:555-566. View in: Pubmed

      • Indoor Ultraviolet Tanning Among U.S. Adolescents and Young Adults: Results From a Prospective Study of Early Onset and Persistence. J Adolesc Health. 2020 10; 67(4):609-611. View in: Pubmed

      • Activity of the Highly Specific RET Inhibitor Selpercatinib (LOXO-292) in Pediatric Patients With Tumors Harboring RET Gene Alterations. JCO Precis Oncol. 2020; 4. View in: Pubmed

      • Sustainable care for children with cancer: a Lancet Oncology Commission. Lancet Oncol. 2020 04; 21(4):e185-e224. View in: Pubmed

      • Re: A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practice. Eur J Cancer. 2020 05; 130:265-266. View in: Pubmed

      • Dairy consumption during adolescence and endometriosis risk. Am J Obstet Gynecol. 2020 03; 222(3):257.e1-257.e16. View in: Pubmed

      • Germ Cell Tumors in Adolescents and Young Adults. J Oncol Pract. 2019 08; 15(8):433-441. View in: Pubmed

      • Survival differences by race/ethnicity among children and adolescents diagnosed with germ cell tumors. Int J Cancer. 2020 05 01; 146(9):2433-2441. View in: Pubmed

      • a-Fetoprotein as a predictor of outcome for children with germ cell tumors: A report from the Malignant Germ Cell International Consortium. Cancer. 2019 10 15; 125(20):3649-3656. View in: Pubmed

      • Global childhood cancer survival estimates and priority-setting: a simulation-based analysis. Lancet Oncol. 2019 07; 20(7):972-983. View in: Pubmed

      • Reply to Letter to the Editor "Staging of acute leukemia based on central nervous system involvement alone: Is it appropriate?" Pediatr Blood Cancer. 2019 08; 66(8):e27756. View in: Pubmed

      • Cancer Treatment-Related Infertility: A Critical Review of the Evidence. JNCI Cancer Spectr. 2019 Mar; 3(1):pkz008. View in: Pubmed

      • Sense of Mission and Subsequent Health and Well-Being Among Young Adults: An Outcome-Wide Analysis. Am J Epidemiol. 2019 04 01; 188(4):664-673. View in: Pubmed

      • Stage at diagnosis for childhood solid cancers in Australia: A population-based study. Cancer Epidemiol. 2019 04; 59:208-214. View in: Pubmed

      • Estimating the total incidence of global childhood cancer: a simulation-based analysis. Lancet Oncol. 2019 04; 20(4):483-493. View in: Pubmed

      • Stage at diagnosis for children with blood cancers in Australia: Application of the Toronto Paediatric Cancer Stage Guidelines in a population-based national childhood cancer registry. Pediatr Blood Cancer. 2019 06; 66(6):e27683. View in: Pubmed

      • Multicenter pre-operative assessment of pediatric ovarian malignancy. J Pediatr Surg. 2019 Sep; 54(9):1921-1925. View in: Pubmed

      • Fundamental problems with pediatric adaptive dosing of carboplatin using nuclear-medicine-based estimates of renal function. Pediatr Blood Cancer. 2019 06; 66(6):e27672. View in: Pubmed

      • Childhood cancer burden: a review of global estimates. Lancet Oncol. 2019 01; 20(1):e42-e53. View in: Pubmed

      • Nutritional status and clinical outcomes in pediatric patients with solid tumors : A systematic review of the literature. Semin Oncol. 2019 02; 46(1):48-56. View in: Pubmed

      • Detection of Relapse by Tumor Markers Versus Imaging in Children and Adolescents With Nongerminomatous Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. J Clin Oncol. 2019 02 10; 37(5):396-402. View in: Pubmed

      • Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 10; 119(7):864-872. View in: Pubmed

      • Klinefelter syndrome in males with germ cell tumors: A report from the Children's Oncology Group. Cancer. 2018 10 01; 124(19):3900-3908. View in: Pubmed

      • Sodium Thiosulfate and Cisplatin-Induced Hearing Loss. N Engl J Med. 2018 09 20; 379(12):1180-1. View in: Pubmed

      • Pediatric vincristine-related vocal fold paralysis. Int J Pediatr Otorhinolaryngol. 2018 11; 114:166-169. View in: Pubmed

      • Is carboplatin-based chemotherapy as effective as cisplatin-based chemotherapy in the treatment of advanced-stage dysgerminoma in children, adolescents and young adults? Gynecol Oncol. 2018 08; 150(2):253-260. View in: Pubmed

      • Comparison of carboplatin versus cisplatin in the treatment of paediatric extracranial malignant germ cell tumours: A report of the Malignant Germ Cell International Consortium. Eur J Cancer. 2018 07; 98:30-37. View in: Pubmed

      • Prevention of cisplatin-induced hearing loss in children: Informing the design of future clinical trials. Cancer Med. 2018 Jul; 7(7):2951-2959. View in: Pubmed

      • Treatment of refractory germ cell tumors in children with paclitaxel, ifosfamide, and carboplatin: A report from the Children's Oncology Group AGCT0521 study. Pediatr Blood Cancer. 2018 08; 65(8):e27111. View in: Pubmed

      • EGF Receptor and mTORC1 Are Novel Therapeutic Targets in Nonseminomatous Germ Cell Tumors. Mol Cancer Ther. 2018 05; 17(5):1079-1089. View in: Pubmed

      • Pediatric Germ Cell Tumors: A Developmental Perspective. Adv Urol. 2018; 2018:9059382. View in: Pubmed

      • Assessing the feasibility and validity of the Toronto Childhood Cancer Stage Guidelines: a population-based registry study. Lancet Child Adolesc Health. 2018 03; 2(3):173-179. View in: Pubmed

      • Adolescents and Young Adults With a "Rare" Cancer: Getting Past Semantics to Optimal Care for Patients With Germ Cell Tumors. Oncologist. 2018 02; 23(2):272. View in: Pubmed

      • DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies. Clin Cancer Res. 2018 05 15; 24(10):2251-2261. View in: Pubmed

      • Adolescent and Young Adult Oncology, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018 Jan; 16(1):66-97. View in: Pubmed

      • Gonadal dysgenesis is associated with worse outcomes in patients with ovarian nondysgerminomatous tumors: A report of the Children's Oncology Group AGCT 0132 study. Pediatr Blood Cancer. 2018 04; 65(4). View in: Pubmed

      • Future cancer research priorities in the USA: a Lancet Oncology Commission. Lancet Oncol. 2017 11; 18(11):e653-e706. View in: Pubmed

      • Family history of cancer in children and adolescents with germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 01; 118(1):121-126. View in: Pubmed

      • DICER1-related Sertoli-Leydig cell tumor and gynandroblastoma: Clinical and genetic findings from the International Ovarian and Testicular Stromal Tumor Registry. Gynecol Oncol. 2017 12; 147(3):521-527. View in: Pubmed

      • T cells from patients with Parkinson's disease recognize a-synuclein peptides. Nature. 2017 06 29; 546(7660):656-661. View in: Pubmed

      • Evaluation of the utility of 99m Tc-MDP bone scintigraphy versus MIBG scintigraphy and cross-sectional imaging for staging patients with neuroblastoma. Pediatr Blood Cancer. 2017 Nov; 64(11). View in: Pubmed

      • The global burden of childhood cancer: Knowing what we do not know. Pediatr Blood Cancer. 2017 08; 64(8). View in: Pubmed

      • Variants in BAK1, SPRY4, and GAB2 are associated with pediatric germ cell tumors: A report from the children's oncology group. Genes Chromosomes Cancer. 2017 07; 56(7):548-558. View in: Pubmed

      • Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. J Clin Oncol. 2017 Apr 10; 35(11):1203-1210. View in: Pubmed

      • Risk of second malignant neoplasms in women and girls with germ cell tumors. Ann Oncol. 2017 02 01; 28(2):329-332. View in: Pubmed

      • Body size from birth through adolescence in relation to risk of benign breast disease in young women. Breast Cancer Res Treat. 2017 02; 162(1):139-149. View in: Pubmed

      • Is surgical resection and observation sufficient for stage I and II sacrococcygeal germ cell tumors? A case series and review. Pediatr Blood Cancer. 2017 05; 64(5). View in: Pubmed

      • Socioeconomic status and global variations in the incidence of neuroblastoma: call for support of population-based cancer registries in low-middle-income countries. Pediatr Blood Cancer. 2017 02; 64(2):321-323. View in: Pubmed

      • Patient-Reported Measures of Hearing Loss and Tinnitus in Pediatric Cancer and Hematopoietic Stem Cell Transplantation: A Systematic Review. J Speech Lang Hear Res. 2016 10 01; 59(5):1247-1252. View in: Pubmed

      • Ovarian Sex Cord-Stromal Tumors. J Oncol Pract. 2016 10; 12(10):940-946. View in: Pubmed

      • Conundrums in the management of malignant ovarian germ cell tumors: Toward lessening acute morbidity and late effects of treatment. Gynecol Oncol. 2016 Nov; 143(2):428-432. View in: Pubmed

      • Can Big Data Shed Light on the Origins of Pediatric Cancer? Pediatrics. 2016 06; 137(6). View in: Pubmed

      • Preoperative risk stratification of children with ovarian tumors. J Pediatr Surg. 2016 Sep; 51(9):1507-12. View in: Pubmed

      • Risk of second gonadal cancers in women and children with germ cell tumors. Cancer. 2016 07 01; 122(13):2076-82. View in: Pubmed

      • Poor adherence to staging guidelines for children with malignant ovarian tumors. J Pediatr Surg. 2016 Sep; 51(9):1513-7. View in: Pubmed

      • A systematic review of patient-reported outcome measures of neuropathy in children, adolescents and young adults. Support Care Cancer. 2016 09; 24(9):3723-8. View in: Pubmed

      • Paediatric cancer stage in population-based cancer registries: the Toronto consensus principles and guidelines. Lancet Oncol. 2016 04; 17(4):e163-e172. View in: Pubmed

      • Paediatric extracranial germ-cell tumours. Lancet Oncol. 2016 04; 17(4):e149-e162. View in: Pubmed

      • Disparities by Sexual Orientation in Frequent Engagement in Cancer-Related Risk Behaviors: A 12-Year Follow-Up. Am J Public Health. 2016 Apr; 106(4):698-706. View in: Pubmed

      • Diagnostic Impact of Peritoneal Fluid Cytology in the Setting of Pediatric Uterine Adnexal Biopsy or Resection. Pediatr Dev Pathol. 2016 Sep/Oct; 19(5):401-408. View in: Pubmed

      • Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative. Cancer. 2016 Jan 15; 122(2):230-7. View in: Pubmed

      • Health care utilization, lifestyle, and emotional factors and mammography practices in the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev. 2015 Nov; 24(11):1699-706. View in: Pubmed

      • Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration. J Clin Oncol. 2015 Sep 20; 33(27):3018-28. View in: Pubmed

      • Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases. Am J Surg Pathol. 2015 Aug; 39(8):1121-31. View in: Pubmed

      • Milk Consumption after Age 9 Years Does Not Predict Age at Menarche. J Nutr. 2015 Aug; 145(8):1900-8. View in: Pubmed

      • Adolescent dietary vitamin D and sun exposure in relation to benign breast disease. Cancer Causes Control. 2015 Aug; 26(8):1181-7. View in: Pubmed

      • Sugar-sweetened beverage consumption and age at menarche in a prospective study of US girls. Hum Reprod. 2015 Mar; 30(3):675-83. View in: Pubmed

      • Impact of central surgical review in a study of malignant germ cell tumors. J Pediatr Surg. 2015 Sep; 50(9):1502-5. View in: Pubmed

      • Revised risk classification for pediatric extracranial germ cell tumors based on 25 years of clinical trial data from the United Kingdom and United States. J Clin Oncol. 2015 Jan 10; 33(2):195-201. View in: Pubmed

      • Determining optimal first-line chemotherapy for good and intermediate prognosis testicular germ cell tumors using decision analysis. J Clin Oncol. 2014 Oct 20; 32(30_suppl):209. View in: Pubmed

      • Reply: Serum microRNA screening for DICER1-associated pleuropulmonary blastoma. Pediatr Blood Cancer. 2014 Dec; 61(12):2331-2. View in: Pubmed

      • Reply to G. Mangili et al and C. Lhommé et al. J Clin Oncol. 2014 Sep 01; 32(25):2816-7. View in: Pubmed

      • Adolescents and young adults with a "rare" cancer: getting past semantics to optimal care for patients with germ cell tumors. Oncologist. 2014 Jul; 19(7):689-92. View in: Pubmed

      • Quitting the "Cancer Tube": a qualitative examination of the process of indoor tanning cessation. Transl Behav Med. 2014 Jun; 4(2):209-19. View in: Pubmed

      • Judicious DICER1 testing and surveillance imaging facilitates early diagnosis and cure of pleuropulmonary blastoma. Pediatr Blood Cancer. 2014 Sep; 61(9):1695-7. View in: Pubmed

      • Masculine boys, feminine girls, and cancer risk behaviors: an 11-year longitudinal study. J Adolesc Health. 2014 Sep; 55(3):373-9. View in: Pubmed

      • Adolescent carotenoid intake and benign breast disease. Pediatrics. 2014 May; 133(5):e1292-8. View in: Pubmed

      • Increase in the incidence of differentiated thyroid carcinoma in children, adolescents, and young adults: a population-based study. J Pediatr. 2014 Jun; 164(6):1481-5. View in: Pubmed

      • Prospective study of peripregnancy consumption of peanuts or tree nuts by mothers and the risk of peanut or tree nut allergy in their offspring. JAMA Pediatr. 2014 Feb; 168(2):156-62. View in: Pubmed

      • Surveillance after initial surgery for pediatric and adolescent girls with stage I ovarian germ cell tumors: report from the Children's Oncology Group. J Clin Oncol. 2014 Feb 10; 32(5):465-70. View in: Pubmed

      • Adolescent and young adult oncology, version 2.2014. J Natl Compr Canc Netw. 2014 Jan; 12(1):21-32; quiz 32. View in: Pubmed

      • Milk consumption during teenage years and risk of hip fractures in older adults. JAMA Pediatr. 2014 Jan; 168(1):54-60. View in: Pubmed

      • Beyond the bench and the bedside: economic and health systems dimensions of global childhood cancer outcomes. Pediatr Blood Cancer. 2014 Mar; 61(3):572-6. View in: Pubmed

      • Vitamin D deficiency in reproductive age Mongolian women: a cross sectional study. J Steroid Biochem Mol Biol. 2014 Jan; 139:1-6. View in: Pubmed

      • Vegetable protein and vegetable fat intakes in pre-adolescent and adolescent girls, and risk for benign breast disease in young women. Breast Cancer Res Treat. 2013 Sep; 141(2):299-306. View in: Pubmed

      • A comparison of migrants to, and women born in, urban Mongolia: demographic, reproductive, anthropometric and lifestyle characteristics. Int Health. 2013 Dec; 5(4):244-50. View in: Pubmed

      • DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors. BMC Cancer. 2013 Jun 27; 13:313. View in: Pubmed

      • Disparities in depressive distress by sexual orientation in emerging adults: the roles of attachment and stress paradigms. Arch Sex Behav. 2014 Jul; 43(5):901-16. View in: Pubmed

      • Influence of hormonal contraceptive use and health beliefs on sexual orientation disparities in Papanicolaou test use. Am J Public Health. 2014 Feb; 104(2):319-25. View in: Pubmed

      • Pilot study of cisplatin, etoposide, bleomycin, and escalating dose cyclophosphamide therapy for children with high risk germ cell tumors: a report of the children's oncology group (COG). Pediatr Blood Cancer. 2013 Oct; 60(10):1602-5. View in: Pubmed

      • Preadolescent and adolescent risk factors for benign breast disease. J Adolesc Health. 2013 May; 52(5 Suppl):S36-40. View in: Pubmed

      • Dairy intakes in older girls and risk of benign breast disease in young women. Cancer Epidemiol Biomarkers Prev. 2013 Apr; 22(4):670-4. View in: Pubmed

      • Global challenges in pediatric oncology. Curr Opin Pediatr. 2013 Feb; 25(1):3-15. View in: Pubmed

      • Updates in the management of ovarian germ cell tumors. Am Soc Clin Oncol Educ Book. 2013. View in: Pubmed

      • Children's Oncology Group's 2013 blueprint for research: rare tumors. Pediatr Blood Cancer. 2013 Jun; 60(6):1016-21. View in: Pubmed

      • Is there a role for carboplatin in the treatment of malignant germ cell tumors? A systematic review of adult and pediatric trials. Pediatr Blood Cancer. 2013 Apr; 60(4):587-92. View in: Pubmed

      • Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia. Pediatrics. 2012 Sep; 130(3):e561-7. View in: Pubmed

      • Scaling up cancer care for children without medical insurance in developing countries: The case of Mexico. Pediatr Blood Cancer. 2013 Feb; 60(2):196-203. View in: Pubmed

      • Fetal and neonatal germ cell tumors. Semin Fetal Neonatal Med. 2012 Aug; 17(4):222-230. View in: Pubmed

      • A rasopathy phenotype with severe congenital hypertrophic obstructive cardiomyopathy associated with a PTPN11 mutation and a novel variant in SOS1. Am J Med Genet A. 2012 Jun; 158A(6):1414-21. View in: Pubmed

      • Sexual-orientation disparities in cigarette smoking in a longitudinal cohort study of adolescents. Nicotine Tob Res. 2013 Jan; 15(1):213-22. View in: Pubmed

      • Management of ovarian and testicular sex cord-stromal tumors in children and adolescents. J Pediatr Hematol Oncol. 2012 May; 34 Suppl 2:S55-63. View in: Pubmed

      • Breast cancer incidence in Mongolia. Cancer Causes Control. 2012 Jul; 23(7):1047-53. View in: Pubmed

      • Long-term impact of a chef on school lunch consumption: findings from a 2-year pilot study in Boston middle schools. J Acad Nutr Diet. 2012 Jun; 112(6):927-33. View in: Pubmed

      • "Accelerated ear-age": a new measure of chemotherapy-induced ototoxicity. Pediatr Blood Cancer. 2012 Nov; 59(5):947-9. View in: Pubmed

      • An unusual case of congenital primitive neuroectodermal tumor with ocular metastasis. J Pediatr Hematol Oncol. 2012 Mar; 34(2):e69-71. View in: Pubmed

      • Use of tanning beds and incidence of skin cancer. J Clin Oncol. 2012 May 10; 30(14):1588-93. View in: Pubmed

      • Young women with family history of breast cancer and their risk factors for benign breast disease. Cancer. 2012 Jun 01; 118(11):2796-803. View in: Pubmed

      • Associations between variants in KITLG, SPRY4, BAK1, and DMRT1 and pediatric germ cell tumors. Genes Chromosomes Cancer. 2012 Mar; 51(3):266-71. View in: Pubmed

      • Randomized trial of fortified milk and supplements to raise 25-hydroxyvitamin D concentrations in schoolchildren in Mongolia. Am J Clin Nutr. 2011 Aug; 94(2):578-84. View in: Pubmed

      • Reproductive health screening disparities and sexual orientation in a cohort study of U.S. adolescent and young adult females. J Adolesc Health. 2011 Nov; 49(5):505-10. View in: Pubmed

      • Changes in incidence of infant cancer: Analysis of SEER data 1992-2007. J Clin Oncol. 2011 May 20; 29(15_suppl):9542. View in: Pubmed

      • Prospective study of growth and development in older girls and risk of benign breast disease in young women. Cancer. 2011 Apr 15; 117(8):1612-20. View in: Pubmed

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