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A. Lindsay Frazier, MD


Pediatric Hematology/Oncology

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Physician

  • Institute Physician
  • Professor of Pediatrics, Harvard Medical School
  • Associate Professor of Epidemiology, Harvard T.H. Chan School of Public Health

Centers/Programs

Clinical Interests

  • Cancer epidemiology
  • Cancer prevention in children
  • Germ cell tumors
  • Global health

Contact Information

  • Appointments888-733-4662 (new)
    617-632-3270 (established)
  • Office Phone Number617-632-2273
  • Fax617-632-5710

Bio

Dr. Frazier received her MD from Dartmouth Medical School in 1984, followed by a pediatric residency at Children’s Hospital Boston and a pediatric hematology-oncology fellowship at DFCI, where she joined the faculty in 1990. She received an ScM from Harvard School of Public Health in 1993. In clinical practice, she concentrates on germ cell tumors, while her epidemiologic research primarily focuses on colorectal cancer screening and prevention.

Board Certification:

  • Pediatric Hematology/Oncology
  • Pediatrics

Fellowship:

  • Boston Children's Hospital/Dana-Farber Cancer Institute, Pediatric Hematology/Oncology

Residency:

  • Boston Children's Hospital, Pediatrics

Medical School:

  • Dartmouth Medical School

Recent Awards:

  • Boston Combined Residency Program Faculty Teaching Honor Roll, 2017-2018

Research

Cancer Prevention in Adolescents, Colorectal Screening, Germ Cell Tumors

Our research focuses on three main areas: (1) adolescent behaviors that predispose to adult malignancy (e.g., diet, tobacco and alcohol consumption, and level of physical activity); (2) prevention policies for both primary and secondary cancer; and (3) treatment of germ cell tumors in pediatric patients. Three cohort studies serve as the basis for this research: Nurses' Health Study I (NHS I), Nurses' Health Study II (NHS II), and the Growing Up Today Study (GUTS).In analyzing tobacco use among the 16,600 children who participate in GUTS, we have focused on identifying factors that predispose children to progress through the stages of tobacco uptake: abstainer, contemplator, experimenter, occasional user, regular user, and addicted user. We found that increased risk of cigarette use was due to excessive weight concerns, willingness to use tobacco promotional items, use of cigars, and low self-esteem. Among women in the NHS I, we have investigated the relation between alcohol use during adolescence, diet during adolescence, and risk of breast cancer. Whereas no effect was demonstrable for alcohol use during adolescence, the null result may reflect only the low level of drinking among this generation of women. However, we found that increased consumption of potatoes, rice, and french fries during adolescence increased risk of breast cancer, as did increased consumption of fish. Refinement of this work is under way via a more extensive adolescent diet questionnaire sent to 60,000 participants of NHS II.We also have completed a cost-effectiveness model of 26 strategies for screening for colorectal cancer, which confirmed that an annual fecal occult blood test with a sigmoidoscopy every 5 years is both effective and cost-effective. Most other strategies recommended recently by a task force of the Agency for Health Care Policy and Research were actually more costly and less effective. The model allows clinicians to examine the tradeoffs between strategies and to tailor recommendations to the patient.In clinical care, Dr. Frazier is the national expert on germ cell tumors in pediatric patients and oversees the care of these patients referred to DFCI. In addition, she is cochair of two national protocols that opened in 1999 for the treatment of low-risk and high-risk pediatric germ cell tumors and chair of the COG Germ Cell subcommittee in COG Rare Tumors.

Neonatal Malignant Disorders: Germ Cell Tumors. Clin Perinatol. 2021 Mar; 48(1):147-165.
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The Global COVID-19 Observatory and Resource Center for Childhood Cancer: A response for the pediatric oncology community by SIOP and St. Jude Global. Pediatr Blood Cancer. 2021 05; 68(5):e28962.
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Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection. Science. 2021 02 05; 371(6529).
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Developing and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell Tumors. Methods Mol Biol. 2021; 2195:263-275.
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Adolescent alcohol, nuts, and fiber: combined effects on benign breast disease risk in young women. NPJ Breast Cancer. 2020 Nov 23; 6(1):61.
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International Trends in the Incidence of Cancer Among Adolescents and Young Adults. J Natl Cancer Inst. 2020 11 01; 112(11):1105-1117.
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Impact of circulating microRNA test (miRNA-371a-3p) on appropriateness of treatment and cost outcomes in patients with Stage I non-seminomatous germ cell tumours. BJU Int. 2020 Oct 30.
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What are the volume and budget needs to provide chemotherapy to all children with acute lymphoblastic leukaemia in Thailand? Development and application of an estimation tool. BMJ Open. 2020 10 26; 10(10):e041901.
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Outcomes of adolescent males with extracranial metastatic germ cell tumors: A report from the Malignant Germ Cell Tumor International Consortium. Cancer. 2021 Jan 15; 127(2):193-202.
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Real-World Application of Pre-Orchiectomy miR-371a-3p Test in Testicular Germ Cell Tumor Management. J Urol. 2021 Jan; 205(1):137-144.
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The use of interval-compressed chemotherapy with the addition of vincristine, irinotecan, and temozolomide for pediatric patients with newly diagnosed desmoplastic small round cell tumor. Pediatr Blood Cancer. 2020 10; 67(10):e28559.
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Contemporary management of ovarian germ cell tumors and remaining controversies. Gynecol Oncol. 2020 08; 158(2):467-475.
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Development of a Data Model and Data Commons for Germ Cell Tumors. JCO Clin Cancer Inform. 2020 06; 4:555-566.
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Indoor Ultraviolet Tanning Among U.S. Adolescents and Young Adults: Results From a Prospective Study of Early Onset and Persistence. J Adolesc Health. 2020 10; 67(4):609-611.
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Activity of the Highly Specific RET Inhibitor Selpercatinib (LOXO-292) in Pediatric Patients With Tumors Harboring RET Gene Alterations. JCO Precis Oncol. 2020; 4.
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Sustainable care for children with cancer: a Lancet Oncology Commission. Lancet Oncol. 2020 04; 21(4):e185-e224.
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Re: A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practice. Eur J Cancer. 2020 05; 130:265-266.
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Dairy consumption during adolescence and endometriosis risk. Am J Obstet Gynecol. 2020 03; 222(3):257.e1-257.e16.
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Germ Cell Tumors in Adolescents and Young Adults. J Oncol Pract. 2019 08; 15(8):433-441.
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Survival differences by race/ethnicity among children and adolescents diagnosed with germ cell tumors. Int J Cancer. 2020 05 01; 146(9):2433-2441.
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a-Fetoprotein as a predictor of outcome for children with germ cell tumors: A report from the Malignant Germ Cell International Consortium. Cancer. 2019 10 15; 125(20):3649-3656.
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Global childhood cancer survival estimates and priority-setting: a simulation-based analysis. Lancet Oncol. 2019 07; 20(7):972-983.
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Reply to Letter to the Editor "Staging of acute leukemia based on central nervous system involvement alone: Is it appropriate?" Pediatr Blood Cancer. 2019 08; 66(8):e27756.
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Cancer Treatment-Related Infertility: A Critical Review of the Evidence. JNCI Cancer Spectr. 2019 Mar; 3(1):pkz008.
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Sense of Mission and Subsequent Health and Well-Being Among Young Adults: An Outcome-Wide Analysis. Am J Epidemiol. 2019 04 01; 188(4):664-673.
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Stage at diagnosis for childhood solid cancers in Australia: A population-based study. Cancer Epidemiol. 2019 04; 59:208-214.
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Estimating the total incidence of global childhood cancer: a simulation-based analysis. Lancet Oncol. 2019 04; 20(4):483-493.
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Stage at diagnosis for children with blood cancers in Australia: Application of the Toronto Paediatric Cancer Stage Guidelines in a population-based national childhood cancer registry. Pediatr Blood Cancer. 2019 06; 66(6):e27683.
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Multicenter pre-operative assessment of pediatric ovarian malignancy. J Pediatr Surg. 2019 Sep; 54(9):1921-1925.
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Fundamental problems with pediatric adaptive dosing of carboplatin using nuclear-medicine-based estimates of renal function. Pediatr Blood Cancer. 2019 06; 66(6):e27672.
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Childhood cancer burden: a review of global estimates. Lancet Oncol. 2019 01; 20(1):e42-e53.
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Nutritional status and clinical outcomes in pediatric patients with solid tumors : A systematic review of the literature. Semin Oncol. 2019 02; 46(1):48-56.
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Detection of Relapse by Tumor Markers Versus Imaging in Children and Adolescents With Nongerminomatous Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. J Clin Oncol. 2019 02 10; 37(5):396-402.
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Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 10; 119(7):864-872.
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Klinefelter syndrome in males with germ cell tumors: A report from the Children's Oncology Group. Cancer. 2018 10 01; 124(19):3900-3908.
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Sodium Thiosulfate and Cisplatin-Induced Hearing Loss. N Engl J Med. 2018 09 20; 379(12):1180-1.
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Pediatric vincristine-related vocal fold paralysis. Int J Pediatr Otorhinolaryngol. 2018 11; 114:166-169.
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Is carboplatin-based chemotherapy as effective as cisplatin-based chemotherapy in the treatment of advanced-stage dysgerminoma in children, adolescents and young adults? Gynecol Oncol. 2018 08; 150(2):253-260.
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Comparison of carboplatin versus cisplatin in the treatment of paediatric extracranial malignant germ cell tumours: A report of the Malignant Germ Cell International Consortium. Eur J Cancer. 2018 07; 98:30-37.
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Prevention of cisplatin-induced hearing loss in children: Informing the design of future clinical trials. Cancer Med. 2018 May 30.
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Treatment of refractory germ cell tumors in children with paclitaxel, ifosfamide, and carboplatin: A report from the Children's Oncology Group AGCT0521 study. Pediatr Blood Cancer. 2018 08; 65(8):e27111.
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EGF Receptor and mTORC1 Are Novel Therapeutic Targets in Nonseminomatous Germ Cell Tumors. Mol Cancer Ther. 2018 05; 17(5):1079-1089.
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Pediatric Germ Cell Tumors: A Developmental Perspective. Adv Urol. 2018; 2018:9059382.
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Assessing the feasibility and validity of the Toronto Childhood Cancer Stage Guidelines: a population-based registry study. Lancet Child Adolesc Health. 2018 03; 2(3):173-179.
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Adolescents and Young Adults With a "Rare" Cancer: Getting Past Semantics to Optimal Care for Patients With Germ Cell Tumors. Oncologist. 2018 02; 23(2):272.
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DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies. Clin Cancer Res. 2018 05 15; 24(10):2251-2261.
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Adolescent and Young Adult Oncology, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2018 Jan; 16(1):66-97.
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Gonadal dysgenesis is associated with worse outcomes in patients with ovarian nondysgerminomatous tumors: A report of the Children's Oncology Group AGCT 0132 study. Pediatr Blood Cancer. 2018 04; 65(4).
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Future cancer research priorities in the USA: a Lancet Oncology Commission. Lancet Oncol. 2017 11; 18(11):e653-e706.
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Family history of cancer in children and adolescents with germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 01; 118(1):121-126.
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DICER1-related Sertoli-Leydig cell tumor and gynandroblastoma: Clinical and genetic findings from the International Ovarian and Testicular Stromal Tumor Registry. Gynecol Oncol. 2017 12; 147(3):521-527.
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T cells from patients with Parkinson's disease recognize a-synuclein peptides. Nature. 2017 06 29; 546(7660):656-661.
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Evaluation of the utility of 99m Tc-MDP bone scintigraphy versus MIBG scintigraphy and cross-sectional imaging for staging patients with neuroblastoma. Pediatr Blood Cancer. 2017 Nov; 64(11).
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The global burden of childhood cancer: Knowing what we do not know. Pediatr Blood Cancer. 2017 08; 64(8).
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Variants in BAK1, SPRY4, and GAB2 are associated with pediatric germ cell tumors: A report from the children's oncology group. Genes Chromosomes Cancer. 2017 07; 56(7):548-558.
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Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. J Clin Oncol. 2017 Apr 10; 35(11):1203-1210.
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Risk of second malignant neoplasms in women and girls with germ cell tumors. Ann Oncol. 2017 02 01; 28(2):329-332.
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Body size from birth through adolescence in relation to risk of benign breast disease in young women. Breast Cancer Res Treat. 2017 02; 162(1):139-149.
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Is surgical resection and observation sufficient for stage I and II sacrococcygeal germ cell tumors? A case series and review. Pediatr Blood Cancer. 2017 05; 64(5).
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Socioeconomic status and global variations in the incidence of neuroblastoma: call for support of population-based cancer registries in low-middle-income countries. Pediatr Blood Cancer. 2017 02; 64(2):321-323.
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Patient-Reported Measures of Hearing Loss and Tinnitus in Pediatric Cancer and Hematopoietic Stem Cell Transplantation: A Systematic Review. J Speech Lang Hear Res. 2016 10 01; 59(5):1247-1252.
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Ovarian Sex Cord-Stromal Tumors. J Oncol Pract. 2016 10; 12(10):940-946.
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Conundrums in the management of malignant ovarian germ cell tumors: Toward lessening acute morbidity and late effects of treatment. Gynecol Oncol. 2016 Nov; 143(2):428-432.
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Can Big Data Shed Light on the Origins of Pediatric Cancer? Pediatrics. 2016 06; 137(6).
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Preoperative risk stratification of children with ovarian tumors. J Pediatr Surg. 2016 Sep; 51(9):1507-12.
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Risk of second gonadal cancers in women and children with germ cell tumors. Cancer. 2016 07 01; 122(13):2076-82.
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Poor adherence to staging guidelines for children with malignant ovarian tumors. J Pediatr Surg. 2016 Sep; 51(9):1513-7.
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A systematic review of patient-reported outcome measures of neuropathy in children, adolescents and young adults. Support Care Cancer. 2016 09; 24(9):3723-8.
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Paediatric cancer stage in population-based cancer registries: the Toronto consensus principles and guidelines. Lancet Oncol. 2016 04; 17(4):e163-e172.
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Paediatric extracranial germ-cell tumours. Lancet Oncol. 2016 04; 17(4):e149-e162.
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Disparities by Sexual Orientation in Frequent Engagement in Cancer-Related Risk Behaviors: A 12-Year Follow-Up. Am J Public Health. 2016 Apr; 106(4):698-706.
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Diagnostic Impact of Peritoneal Fluid Cytology in the Setting of Pediatric Uterine Adnexal Biopsy or Resection. Pediatr Dev Pathol. 2016 Sep/Oct; 19(5):401-408.
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Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative. Cancer. 2016 Jan 15; 122(2):230-7.
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Health care utilization, lifestyle, and emotional factors and mammography practices in the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev. 2015 Nov; 24(11):1699-706.
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Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration. J Clin Oncol. 2015 Sep 20; 33(27):3018-28.
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Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases. Am J Surg Pathol. 2015 Aug; 39(8):1121-31.
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Milk Consumption after Age 9 Years Does Not Predict Age at Menarche. J Nutr. 2015 Aug; 145(8):1900-8.
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Adolescent dietary vitamin D and sun exposure in relation to benign breast disease. Cancer Causes Control. 2015 Aug; 26(8):1181-7.
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Sugar-sweetened beverage consumption and age at menarche in a prospective study of US girls. Hum Reprod. 2015 Mar; 30(3):675-83.
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Impact of central surgical review in a study of malignant germ cell tumors. J Pediatr Surg. 2015 Sep; 50(9):1502-5.
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Revised risk classification for pediatric extracranial germ cell tumors based on 25 years of clinical trial data from the United Kingdom and United States. J Clin Oncol. 2015 Jan 10; 33(2):195-201.
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Determining optimal first-line chemotherapy for good and intermediate prognosis testicular germ cell tumors using decision analysis. J Clin Oncol. 2014 Oct 20; 32(30_suppl):209.
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Reply: Serum microRNA screening for DICER1-associated pleuropulmonary blastoma. Pediatr Blood Cancer. 2014 Dec; 61(12):2331-2.
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Reply to G. Mangili et al and C. Lhommé et al. J Clin Oncol. 2014 Sep 01; 32(25):2816-7.
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Adolescents and young adults with a "rare" cancer: getting past semantics to optimal care for patients with germ cell tumors. Oncologist. 2014 Jul; 19(7):689-92.
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Quitting the "Cancer Tube": a qualitative examination of the process of indoor tanning cessation. Transl Behav Med. 2014 Jun; 4(2):209-19.
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Judicious DICER1 testing and surveillance imaging facilitates early diagnosis and cure of pleuropulmonary blastoma. Pediatr Blood Cancer. 2014 Sep; 61(9):1695-7.
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Masculine boys, feminine girls, and cancer risk behaviors: an 11-year longitudinal study. J Adolesc Health. 2014 Sep; 55(3):373-9.
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Adolescent carotenoid intake and benign breast disease. Pediatrics. 2014 May; 133(5):e1292-8.
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Increase in the incidence of differentiated thyroid carcinoma in children, adolescents, and young adults: a population-based study. J Pediatr. 2014 Jun; 164(6):1481-5.
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Prospective study of peripregnancy consumption of peanuts or tree nuts by mothers and the risk of peanut or tree nut allergy in their offspring. JAMA Pediatr. 2014 Feb; 168(2):156-62.
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Surveillance after initial surgery for pediatric and adolescent girls with stage I ovarian germ cell tumors: report from the Children's Oncology Group. J Clin Oncol. 2014 Feb 10; 32(5):465-70.
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Adolescent and young adult oncology, version 2.2014. J Natl Compr Canc Netw. 2014 Jan; 12(1):21-32; quiz 32.
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Milk consumption during teenage years and risk of hip fractures in older adults. JAMA Pediatr. 2014 Jan; 168(1):54-60.
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Beyond the bench and the bedside: economic and health systems dimensions of global childhood cancer outcomes. Pediatr Blood Cancer. 2014 Mar; 61(3):572-6.
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Vitamin D deficiency in reproductive age Mongolian women: a cross sectional study. J Steroid Biochem Mol Biol. 2014 Jan; 139:1-6.
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Vegetable protein and vegetable fat intakes in pre-adolescent and adolescent girls, and risk for benign breast disease in young women. Breast Cancer Res Treat. 2013 Sep; 141(2):299-306.
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A comparison of migrants to, and women born in, urban Mongolia: demographic, reproductive, anthropometric and lifestyle characteristics. Int Health. 2013 Dec; 5(4):244-50.
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DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors. BMC Cancer. 2013 Jun 27; 13:313.
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Disparities in depressive distress by sexual orientation in emerging adults: the roles of attachment and stress paradigms. Arch Sex Behav. 2014 Jul; 43(5):901-16.
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Influence of hormonal contraceptive use and health beliefs on sexual orientation disparities in Papanicolaou test use. Am J Public Health. 2014 Feb; 104(2):319-25.
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Pilot study of cisplatin, etoposide, bleomycin, and escalating dose cyclophosphamide therapy for children with high risk germ cell tumors: a report of the children's oncology group (COG). Pediatr Blood Cancer. 2013 Oct; 60(10):1602-5.
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Preadolescent and adolescent risk factors for benign breast disease. J Adolesc Health. 2013 May; 52(5 Suppl):S36-40.
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Dairy intakes in older girls and risk of benign breast disease in young women. Cancer Epidemiol Biomarkers Prev. 2013 Apr; 22(4):670-4.
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Global challenges in pediatric oncology. Curr Opin Pediatr. 2013 Feb; 25(1):3-15.
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Updates in the management of ovarian germ cell tumors. Am Soc Clin Oncol Educ Book. 2013.
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Children's Oncology Group's 2013 blueprint for research: rare tumors. Pediatr Blood Cancer. 2013 Jun; 60(6):1016-21.
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Is there a role for carboplatin in the treatment of malignant germ cell tumors? A systematic review of adult and pediatric trials. Pediatr Blood Cancer. 2013 Apr; 60(4):587-92.
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Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia. Pediatrics. 2012 Sep; 130(3):e561-7.
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Scaling up cancer care for children without medical insurance in developing countries: The case of Mexico. Pediatr Blood Cancer. 2013 Feb; 60(2):196-203.
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Fetal and neonatal germ cell tumors. Semin Fetal Neonatal Med. 2012 Aug; 17(4):222-230.
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A rasopathy phenotype with severe congenital hypertrophic obstructive cardiomyopathy associated with a PTPN11 mutation and a novel variant in SOS1. . 2012 Jun; 158A(6):1414-21.
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Sexual-orientation disparities in cigarette smoking in a longitudinal cohort study of adolescents. Nicotine Tob Res. 2013 Jan; 15(1):213-22.
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Management of ovarian and testicular sex cord-stromal tumors in children and adolescents. J Pediatr Hematol Oncol. 2012 May; 34 Suppl 2:S55-63.
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Breast cancer incidence in Mongolia. Cancer Causes Control. 2012 Jul; 23(7):1047-53.
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Long-term impact of a chef on school lunch consumption: findings from a 2-year pilot study in Boston middle schools. J Acad Nutr Diet. 2012 Jun; 112(6):927-33.
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"Accelerated ear-age": a new measure of chemotherapy-induced ototoxicity. Pediatr Blood Cancer. 2012 Nov; 59(5):947-9.
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An unusual case of congenital primitive neuroectodermal tumor with ocular metastasis. J Pediatr Hematol Oncol. 2012 Mar; 34(2):e69-71.
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Use of tanning beds and incidence of skin cancer. J Clin Oncol. 2012 May 10; 30(14):1588-93.
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Young women with family history of breast cancer and their risk factors for benign breast disease. Cancer. 2012 Jun 01; 118(11):2796-803.
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Associations between variants in KITLG, SPRY4, BAK1, and DMRT1 and pediatric germ cell tumors. Genes Chromosomes Cancer. 2012 Mar; 51(3):266-71.
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Randomized trial of fortified milk and supplements to raise 25-hydroxyvitamin D concentrations in schoolchildren in Mongolia. Am J Clin Nutr. 2011 Aug; 94(2):578-84.
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Reproductive health screening disparities and sexual orientation in a cohort study of U.S. adolescent and young adult females. J Adolesc Health. 2011 Nov; 49(5):505-10.
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Changes in incidence of infant cancer: Analysis of SEER data 1992-2007. J Clin Oncol. 2011 May 20; 29(15_suppl):9542.
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Prospective study of growth and development in older girls and risk of benign breast disease in young women. Cancer. 2011 Apr 15; 117(8):1612-20.
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Impact of maternal communication about skin, cervical, and lung cancer prevention on adolescent prevention behaviors. J Adolesc Health. 2011 Jul; 49(1):93-6.
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Dietary intake of vitamin D during adolescence and risk of multiple sclerosis. J Neurol. 2011 Mar; 258(3):479-85.
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Decision analysis to compare treatment strategies for Stage I/favorable histology Wilms tumor. Pediatr Blood Cancer. 2010 Jul 01; 54(7):879-84.
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Prospective study of adolescent alcohol consumption and risk of benign breast disease in young women. Pediatrics. 2010 May; 125(5):e1081-7.
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Adolescent diet in relation to breast cancer risk among premenopausal women. Cancer Epidemiol Biomarkers Prev. 2010 Mar; 19(3):689-96.
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Sexual orientation and drug use in a longitudinal cohort study of U.S. adolescents. Addict Behav. 2010 May; 35(5):517-21.
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Metachronous mediastinal seminoma occurring after intracranial germinoma in an adolescent. J Pediatr Hematol Oncol. 2009 Nov; 31(11):861-4.
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A role for Lin28 in primordial germ-cell development and germ-cell malignancy. Nature. 2009 Aug 13; 460(7257):909-13.
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Mothers' intention for their daughters and themselves to receive the human papillomavirus vaccine: a national study of nurses. Pediatrics. 2009 Jun; 123(6):1439-45.
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Dairy consumption and female height growth: prospective cohort study. Cancer Epidemiol Biomarkers Prev. 2009 Jun; 18(6):1881-7.
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Maternal gestational weight gain and offspring weight in adolescence. Obstet Gynecol. 2008 Nov; 112(5):999-1006.
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Red meat consumption during adolescence among premenopausal women and risk of breast cancer. Cancer Epidemiol Biomarkers Prev. 2008 Aug; 17(8):2146-51.
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Application of the adult international germ cell classification system to pediatric malignant non-seminomatous germ cell tumors: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2008 Apr; 50(4):746-51.
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Child abuse and smoking among young women: the importance of severity, accumulation, and timing. J Adolesc Health. 2008 Jul; 43(1):55-63.
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Patterns and determinants of physical activity in U.S. adolescents. J Adolesc Health. 2008 Apr; 42(4):369-77.
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Pediatric Germ Cell Tumors. Nathan and Oski's Hematology of Infancy and Childhood. Drs. Orkin, Ginburg, Nathan, Look, Fisher and Lux, eds. 2008; in press.

Effects of vitamin D fortified milk on vitamin D status in Mongolian school age children. Asia Pac J Clin Nutr. 2008; 17(1):68-71.
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Predicting sexual initiation in a prospective cohort of adolescents. Arch Ped Adol Med. 2008; in press..

Cancer Prevention, Chapter 54. Nutrition in Pediatrics, Basic Science and Clinical Applications. Drs. Christopher Duggan, John B. Watkins, W. Allan Walker, eds. 2008; in press.

Predicting sexual initiation in a prospective cohort study of adolescents. Arch Pediatr Adolesc Med. 2008 Jan; 162(1):55-9.
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Application of the adult international germ cell classification system to pediatric malignant non-seminomatous germ cell tumors: a report from the Children’s Oncology Group. Pediatric Blood and Cancer. 2007; in press.

Milk consumption and the prepubertal somatotropic axis. Nutr J. 2007 Sep 27; 6:28.
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Household smoking restrictions and adolescent smoking. Am J Health Promot. 2007 Sep-Oct; 22(1):15-21.
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Longitudinal relationship between television viewing and leisure-time physical activity during adolescence. Pediatrics. 2007 Feb; 119(2):e314-9.
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Combined effects of granulocyte colony stimulating factor and radiation. Clin Nucl Med. 2007 Jan; 32(1):39-41.
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Prognostic factors in children with extragonadal malignant germ cell tumors: a pediatric intergroup study. J Clin Oncol. 2006 Jun 01; 24(16):2544-8.
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Frequent tanning bed use, weight concerns, and other health risk behaviors in adolescent females (United States). Cancer Causes Control. 2006 Jun; 17(5):679-86.
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Sun protection practices among offspring of women with personal or family history of skin cancer. Pediatrics. 2006 Apr; 117(4):e688-94.
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Results of a union-based smoking cessation intervention for apprentice iron workers. Cancer Causes Control. 2006; 17(1):53-61.

Results of a union-based smoking cessation intervention for apprentice iron workers (United States). Cancer Causes Control. 2006 Feb; 17(1):53-61.
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Breast-feeding and overweight in adolescence: within-family analysis [corrected]. Epidemiology. 2006 Jan; 17(1):112-4.
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Reducing cigarette smoking among working adolescents: results from the SMART study. Cancer Causes Control. 2005 Dec; 16(10):1159-64.
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Reducing Cigarette Smoking Among Working Adolescents: Results from the SMART Study. Cancer Causes Control. 2005; 16(10):1159-64.

Amifostine does not protect against the ototoxicity of high-dose cisplatin combined with etoposide and bleomycin in pediatric germ-cell tumors: a Children's Oncology Group study. Cancer. 2005 Aug 15; 104(4):841-7.
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Family dinner and adolescent overweight. Obes Res. 2005 May; 13(5):900-6.
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High school dietary dairy intake and teenage acne. J Am Acad Dermatol. 2005 Feb; 52(2):207-14.
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Adult recall of adolescent diet: reproducibility and comparison with maternal reporting. Am J Epidemiol. 2005 Jan 01; 161(1):89-97.
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Development of a scale to measure adolescents' beliefs and attitudes about postponing sexual initiation. J Adolesc Health. 2004 Nov; 35(5):425.e1-10.
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State tobacco excise taxes and adolescent smoking behaviors in the United States. J Public Health Manag Pract. 2004 Nov-Dec; 10(6):490-6.
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The influence of wanting to look like media figures on adolescent physical activity. J Adolesc Health. 2004 Jul; 35(1):41-50.
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Adolescent diet and risk of breast cancer. Cancer Causes Control. 2004 Feb; 15(1):73-82.
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Feasibility of implementing intervention methods in an adolescent worksite tobacco control study. Tob Control. 2003; 12 Suppl 4:IV40-5.

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The feasibility evaluating a tobacco control intervention for working youth. Tob Control. 2003; 12 Suppl 4:IV34-9.

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Outcome of childhood malignant non-seminomatous germ cell tumors (MGCT) according to adult International Germ Cell Classification System (IGCCC). American Society of Clinical Oncology. 2003; 3226.

Employed adolescents and beliefs about self-efficacy to avoid smoking. Addict Behav. 2003; 28(4):613-26.

Smoking, getting drunk, and engaging in bulimic behaviors: in which order are the behaviors adopted? J Am Acad Child Adolesc Psychiatry. 2002 Jul; 41(7):846-53.
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Use of sunscreen, sunburning rates, and tanning bed use among more than 10 000 US children and adolescents. Pediatrics. 2002 Jun; 109(6):1009-14.
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Prevalence and correlates of pelvic examinations in sexually active female adolescents. Ambul Pediatr. 2002 May-Jun; 2(3):212-7.
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Comparing physical activity questionnaires for youth: seasonal vs annual format. Am J Prev Med. 2001 May; 20(4):282-5.
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Relation of childhood diet and body size to menarche and adolescent growth in girls. Am J Epidemiol. 2000 Sep 01; 152(5):446-52.
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Activity, dietary intake, and weight changes in a longitudinal study of preadolescent and adolescent boys and girls. Pediatrics. 2000 Apr; 105(4):E56.
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Family dinner and diet quality among older children and adolescents. Arch Fam Med. 2000 Mar; 9(3):235-40.
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Nutrition and cancer. Int Semin Pediatr Gastroenterol Nutr. 2000; 9:10-15.

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Reproducibility and validity of maternal recall of pregnancy-related events. Epidemiology. 1999 Nov; 10(6):774-7.
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Weight concerns, weight control behaviors, and smoking initiation. Pediatrics. 1999 Oct; 104(4 Pt 1):918-24.
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Overweight, weight concerns, and bulimic behaviors among girls and boys. J Am Acad Child Adolesc Psychiatry. 1999 Jun; 38(6):754-60.
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Validation of a youth/adolescent food frequency questionnaire. Prev Med. 1997 Nov-Dec; 26(6):808-16.
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Physical activity and reduced risk of colon cancer: implications for prevention. Cancer Causes Control. 1997 Jul; 8(4):649-67.
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Treatment of endodermal sinus tumor in children using a regimen that lacks bleomycin. Med Pediatr Oncol. 1996 Aug; 27(2):69-73.
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Reproducibility of recall of adolescent diet: Nurses' Health Study (United States). Cancer Causes Control. 1995 Nov; 6(6):499-506.
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Models of breast cancer show that risk is set by events of early life: prevention efforts must shift focus. Cancer Epidemiol Biomarkers Prev. 1995 Jul-Aug; 4(5):567-71.
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A gamma/delta+ T cell leukemia bearing a novel t(8;14) (q21:q11) translocation demonstrates spontaneous in vitro natural killer-like activity. Blood. 1992; 79(6):1523-31.

The interaction of signal transduction pathways in FRTL5 thyroid follicular cells: studies with stable expression of beta 2-adrenergic receptors. Endocrinology. 1991 Mar; 128(3):1359-68.
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Isolation of TSH and LH/CG receptor cDNAs from human thyroid: regulation by tissue specific splicing. Mol Endocrinol. 1990 Aug; 4(8):1264-76.
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