Benjamin L. Schlechter, MD

My research interests focus on clinical innovations for patients with gastrointestinal malignancies. I am the Harvard-wide principal investigator for the PANOVA-3 clinical trial studying tumor treating fields in locally advanced pancreatic cancer; NUC-3373, a novel fluorouracil-like drug for colorectal cancer; and the ECOG EA2165 study of nivolumab after chemoradiotherapy for anal squamous cancer. I am on the Data Safety Monitoring Committees of PEN221 for advanced neuroendocrine tumors as well as AbGen107 for advanced gastrointestinal malignancies. I also have enrolled patients in multiple phase I, II, and III clinical trials for gastrointestinal malignancies. I was a lead enroller in the CATIQ phase II trial of isoquercetin to inhibit protein disulfide isomerase to prevent malignancy associated thrombosis in ambulatory cancer patients and have been an active participant in a study of fixed-dose versus weight- based enoxaparin as thromboprophylaxis for hospitalized cancer patients. In the past, I worked as a bench researcher in carcinogenesis in the laboratory of Carol Rosenberg at Boston University Medical Center and at the Wyss Institute for Biologically Inspired Engineering under the direction of Donald Ingber at HMS.