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Dr. Gabuzda received her MD from Harvard Medical School in 1983 and did her postgraduate training in internal medicine and neurology at Massachusetts General Hospital. After completing research fellowships at Johns Hopkins University and DFCI, she joined the DFCI faculty in 1991. She is primarily involved in basic laboratory research on HIV replication and disease mechanisms in AIDS.
HIV Molecular Biology and Pathogenesis
The Gabuzda lab uses genetic, biochemical, metabolomic, systems biology, and computational approaches to study HIV infection and comorbidities including cancer. Research interests include understanding viral, host, and environmental factors that determine clinical outcomes, therapeutic responses, and accelerated aging. Current projects include studies on:
The lab is proficient at bioinformatic, computational, and systems biology approaches including generation, analysis, interpretation, and visualization of large data sets, big data handling, and using bioinformatic software and R programs for data integration, network prediction, pathway analysis, and modeling. The lab also uses machine learning and other computational approaches to model longitudinal trajectories and identify new predictors of clinical outcomes. The long-term goal is gaining multidisciplinary knowledge that leads to progress in personalized medicine for HIV-infected and aging populations.
Complete Publications List: http://www.ncbi.nlm.nih.gov/sites/myncbi/dana.gabuzda.1/collections/47703338/public/
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