Bonne S, Tufariello A, Coles Z, Hohl B, Ostermann M, Boxer P, Sloan-Power E, Gusmano M, Glass NE, Kunac A, Livingston D. Identifying participants for inclusion in hospital-based violence intervention: An analysis of 18 years of urban firearm recidivism. J Trauma Acute Care Surg. 2020 Jul; 89(1):68-73.
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Hatchi E, Livingston DM. Opening a Door to PARP Inhibitor-Induced Lethality in HR-Proficient Human Tumor Cells. Cancer Cell. 2020 Feb 10; 37(2):139-140.
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Vohhodina J, Toomire KJ, Petit SA, Micevic G, Kumari G, Botchkarev VV, Li Z, Livingston DM, Hu Y. RAP80 and BRCA1 PARsylation protect chromosome integrity by preventing retention of BRCA1-B/C complexes in DNA repair foci. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):2084-2091.
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Wang H, Xiang D, Liu B, He A, Randle HJ, Zhang KX, Dongre A, Sachs N, Clark AP, Tao L, Chen Q, Botchkarev VV, Xie Y, Dai N, Clevers H, Li Z, Livingston DM. Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer. Cell. 2019 06 27; 178(1):135-151.e19.
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Li AG, Murphy EC, Culhane AC, Powell E, Wang H, Bronson RT, Von T, Giobbie-Hurder A, Gelman RS, Briggs KJ, Piwnica-Worms H, Zhao JJ, Kung AL, Kaelin WG, Livingston DM. BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1a activation. Proc Natl Acad Sci U S A. 2018 10 09; 115(41):E9600-E9609.
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Pena G, Michalski C, Donnelly RJ, Qin Y, Sifri ZC, Mosenthal AC, Livingston DH, Spolarics Z. Trauma-Induced Acute X Chromosome Skewing in White Blood Cells Represents an Immuno-Modulatory Mechanism Unique to Females and a Likely Contributor to Sex-Based Outcome Differences. Shock. 2017 04; 47(4):402-408.
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Hill SJ, Mordes DA, Cameron LA, Neuberg DS, Landini S, Eggan K, Livingston DM. Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage. Proc Natl Acad Sci U S A. 2016 11 29; 113(48):E7701-E7709.
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Liu JF, Palakurthi S, Zeng Q, Zhou S, Ivanova E, Huang W, Zervantonakis IK, Selfors LM, Shen Y, Pritchard CC, Zheng M, Adleff V, Papp E, Piao H, Novak M, Fotheringham S, Wulf GM, English J, Kirschmeier PT, Velculescu VE, Paweletz C, Mills GB, Livingston DM, Brugge JS, Matulonis UA, Drapkin R. Establishment of Patient-Derived Tumor Xenograft Models of Epithelial Ovarian Cancer for Preclinical Evaluation of Novel Therapeutics. Clin Cancer Res. 2017 Mar 01; 23(5):1263-1273.
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Wang H, Bierie B, Li AG, Pathania S, Toomire K, Dimitrov SD, Liu B, Gelman R, Giobbie-Hurder A, Feunteun J, Polyak K, Livingston DM. BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells. Mol Cell. 2016 07 21; 63(2):277-292.
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Kozar RA, Arbabi S, Stein DM, Shackford SR, Barraco RD, Biffl WL, Brasel KJ, Cooper Z, Fakhry SM, Livingston D, Moore F, Luchette F. Injury in the aged: Geriatric trauma care at the crossroads. J Trauma Acute Care Surg. 2015 Jun; 78(6):1197-209.
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Brown M, Chinnaiyan A, Farsetti A, Livingston DM, Loda M, Schuele R, Mihich E. 26th Pezcoller symposium: cancers driven by hormones. Cancer Res. 2015 Apr 01; 75(7):1177-80.
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Hatchi E, Skourti-Stathaki K, Ventz S, Pinello L, Yen A, Kamieniarz-Gdula K, Dimitrov S, Pathania S, McKinney KM, Eaton ML, Kellis M, Hill SJ, Parmigiani G, Proudfoot NJ, Livingston DM. BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair. Mol Cell. 2015 Feb 19; 57(4):636-647.
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White EA, Kramer RE, Hwang JH, Pores Fernando AT, Naetar N, Hahn WC, Roberts TM, Schaffhausen BS, Livingston DM, Howley PM. Papillomavirus E7 oncoproteins share functions with polyomavirus small T antigens. J Virol. 2015 Mar; 89(5):2857-65.
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Baratta MG, Schinzel AC, Zwang Y, Bandopadhayay P, Bowman-Colin C, Kutt J, Curtis J, Piao H, Wong LC, Kung AL, Beroukhim R, Bradner JE, Drapkin R, Hahn WC, Liu JF, Livingston DM. An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinoma. Proc Natl Acad Sci U S A. 2015 Jan 06; 112(1):232-7.
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Pathania S, Bade S, Le Guillou M, Burke K, Reed R, Bowman-Colin C, Su Y, Ting DT, Polyak K, Richardson AL, Feunteun J, Garber JE, Livingston DM. BRCA1 haploinsufficiency for replication stress suppression in primary cells. Nat Commun. 2014 Nov 17; 5:5496.
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Hu Y, Petit SA, Ficarro SB, Toomire KJ, Xie A, Lim E, Cao SA, Park E, Eck MJ, Scully R, Brown M, Marto JA, Livingston DM. PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair. Cancer Discov. 2014 Dec; 4(12):1430-47.
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Smith JA, Haberstroh FS, White EA, Livingston DM, DeCaprio JA, Howley PM. SMCX and components of the TIP60 complex contribute to E2 regulation of the HPV E6/E7 promoter. Virology. 2014 Nov; 468-470:311-321.
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Hill SJ, Rolland T, Adelmant G, Xia X, Owen MS, Dricot A, Zack TI, Sahni N, Jacob Y, Hao T, McKinney KM, Clark AP, Reyon D, Tsai SQ, Joung JK, Beroukhim R, Marto JA, Vidal M, Gaudet S, Hill DE, Livingston DM. Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. Genes Dev. 2014 Sep 01; 28(17):1957-75.
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Hill SJ, Clark AP, Silver DP, Livingston DM. BRCA1 pathway function in basal-like breast cancer cells. Mol Cell Biol. 2014 Oct; 34(20):3828-42.
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Pores Fernando AT, Andrabi S, Cizmecioglu O, Zhu C, Livingston DM, Higgins JM, Schaffhausen BS, Roberts TM. Polyoma small T antigen triggers cell death via mitotic catastrophe. Oncogene. 2015 May 07; 34(19):2483-92.
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Naetar N, Soundarapandian V, Litovchick L, Goguen KL, Sablina AA, Bowman-Colin C, Sicinski P, Hahn WC, DeCaprio JA, Livingston DM. PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length. Mol Cell. 2014 Jun 19; 54(6):932-45.
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Dimitrov SD, Lu D, Naetar N, Hu Y, Pathania S, Kanellopoulou C, Livingston DM. Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle. Genes Dev. 2013 Oct 15; 27(20):2274-91.
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Kaelin W, Livingston D, Loda M, Vousden K, Mihich E. Twenty-fifth annual Pezcoller Symposium: Metabolism and tumorigenesis. Cancer Res. 2013 Oct 15; 73(20):6124-7.
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Bowman-Colin C, Xia B, Bunting S, Klijn C, Drost R, Bouwman P, Fineman L, Chen X, Culhane AC, Cai H, Rodig SJ, Bronson RT, Jonkers J, Nussenzweig A, Kanellopoulou C, Livingston DM. Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer. Proc Natl Acad Sci U S A. 2013 May 21; 110(21):8632-7.
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Marais R, Sellers W, Livingston D, Mihich E. Twenty-fourth annual Pezcoller symposium: Molecular basis for resistance to targeted agents. Cancer Res. 2013 Feb 01; 73(3):1046-9.
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Kwiatt ME, Patel MS, Ross SE, Lachant MT, MacNew HG, Ochsner MG, Norwood SH, Speier L, Kozar R, Gerber JA, Rowell S, Krishnakumar S, Livingston DH, Manis G, Haan JM. Is low-molecular-weight heparin safe for venous thromboembolism prophylaxis in patients with traumatic brain injury? A Western Trauma Association multicenter study. J Trauma Acute Care Surg. 2012 Sep; 73(3):625-8.
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Jirawatnotai S, Hu Y, Livingston DM, Sicinski P. Proteomic identification of a direct role for cyclin d1 in DNA damage repair. Cancer Res. 2012 Sep 01; 72(17):4289-93.
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Silver DP, Livingston DM. Mechanisms of BRCA1 tumor suppression. Cancer Discov. 2012 Aug; 2(8):679-84.
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Ciccia A, Nimonkar AV, Hu Y, Hajdu I, Achar YJ, Izhar L, Petit SA, Adamson B, Yoon JC, Kowalczykowski SC, Livingston DM, Haracska L, Elledge SJ. Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress. Mol Cell. 2012 Aug 10; 47(3):396-409.
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Homnick A, Sifri Z, Yonclas P, Mohr A, Livingston D. The temporal course of intracranial haemorrhage progression: how long is observation necessary? Injury. 2012 Dec; 43(12):2122-5.
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Friedl P, Hubbell J, Livingston D, Mihich E. Twenty-third annual Pezcoller Symposium: engineering influences in cancer research. Cancer Res. 2012 Feb 15; 72(4):841-4.
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Pathania S, Nguyen J, Hill SJ, Scully R, Adelmant GO, Marto JA, Feunteun J, Livingston DM. BRCA1 is required for postreplication repair after UV-induced DNA damage. Mol Cell. 2011 Oct 21; 44(2):235-51.
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Jirawatnotai S, Hu Y, Michowski W, Elias JE, Becks L, Bienvenu F, Zagozdzon A, Goswami T, Wang YE, Clark AB, Kunkel TA, van Harn T, Xia B, Correll M, Quackenbush J, Livingston DM, Gygi SP, Sicinski P. A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers. Nature. 2011 Jun 08; 474(7350):230-4.
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Zimmer SN, Zhou Q, Zhou T, Cheng Z, Abboud-Werner SL, Horn D, Lecocke M, White R, Krivtsov AV, Armstrong SA, Kung AL, Livingston DM, Rebel VI. Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis. Blood. 2011 Jul 07; 118(1):69-79.
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Hu Y, Scully R, Sobhian B, Xie A, Shestakova E, Livingston DM. RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev. 2011 Apr 01; 25(7):685-700.
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Rio Frio T, Bahubeshi A, Kanellopoulou C, Hamel N, Niedziela M, Sabbaghian N, Pouchet C, Gilbert L, O'Brien PK, Serfas K, Broderick P, Houlston RS, Lesueur F, Bonora E, Muljo S, Schimke RN, Bouron-Dal Soglio D, Arseneau J, Schultz KA, Priest JR, Nguyen VH, Harach HR, Livingston DM, Foulkes WD, Tischkowitz M. DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors. JAMA. 2011 Jan 05; 305(1):68-77.
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Bernards R, Filipowicz W, Livingston DM, Mihich E. Twenty-second annual Pezcoller Symposium: RNA biology and cancer. Cancer Res. 2010 Dec 15; 70(24):10034-7.
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Joukov V, De Nicolo A, Rodriguez A, Walter JC, Livingston DM. Centrosomal protein of 192 kDa (Cep192) promotes centrosome-driven spindle assembly by engaging in organelle-specific Aurora A activation. Proc Natl Acad Sci U S A. 2010 Dec 07; 107(49):21022-7.
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O'Donovan PJ, Livingston DM. BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair. Carcinogenesis. 2010 Jun; 31(6):961-7.
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Sheng Q, Liu X, Fleming E, Yuan K, Piao H, Chen J, Moustafa Z, Thomas RK, Greulich H, Schinzel A, Zaghlul S, Batt D, Ettenberg S, Meyerson M, Schoeberl B, Kung AL, Hahn WC, Drapkin R, Livingston DM, Liu JF. An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells. Cancer Cell. 2010 Mar 16; 17(3):298-310.
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Mihich E, Pandolfi PP, Livingston D. Twenty-first annual Pezcoller Symposium: Unconventional Therapeutic Targets in Cancer. Cancer Res. 2010 Jan 01; 70(1):14-7.
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Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature. 2009 Nov 05; 462(7269):108-12.
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Livingston DM. Cancer. Complicated supercomplexes. Science. 2009 May 01; 324(5927):602-3.
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Kanellopoulou C, Muljo SA, Dimitrov SD, Chen X, Colin C, Plath K, Livingston DM. X chromosome inactivation in the absence of Dicer. Proc Natl Acad Sci U S A. 2009 Jan 27; 106(4):1122-7.
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Howley PM, Livingston DM. Small DNA tumor viruses: large contributors to biomedical sciences. Virology. 2009 Feb 20; 384(2):256-9.
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Erkko H, Dowty JG, Nikkilä J, Syrjäkoski K, Mannermaa A, Pylkäs K, Southey MC, Holli K, Kallioniemi A, Jukkola-Vuorinen A, Kataja V, Kosma VM, Xia B, Livingston DM, Winqvist R, Hopper JL. Penetrance analysis of the PALB2 c.1592delT founder mutation. Clin Cancer Res. 2008 Jul 15; 14(14):4667-71.
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Vives MJ, Kishan S, Asghar J, Peng B, Reiter MF, Milo S, Livingston D. Spinal injuries in pedestrians struck by motor vehicles. J Spinal Disord Tech. 2008 Jun; 21(4):281-7.
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Livingston DM, Silver DP. Cancer: crossing over to drug resistance. Nature. 2008 Feb 28; 451(7182):1066-7.
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Pujana MA, Han JD, Starita LM, Stevens KN, Tewari M, Ahn JS, Rennert G, Moreno V, Kirchhoff T, Gold B, Assmann V, Elshamy WM, Rual JF, Levine D, Rozek LS, Gelman RS, Gunsalus KC, Greenberg RA, Sobhian B, Bertin N, Venkatesan K, Ayivi-Guedehoussou N, Solé X, Hernández P, Lázaro C, Nathanson KL, Weber BL, Cusick ME, Hill DE, Offit K, Livingston DM, Gruber SB, Parvin JD, Vidal M. Network modeling links breast cancer susceptibility and centrosome dysfunction. Nat Genet. 2007 Nov; 39(11):1338-49.
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Chan YF, Lavery R, Fox N, Kwon R, Zinzuwadia S, Massone R, Livingston D. Effect of an educational video on emergency department patient stroke knowledge. J Emerg Med. 2008 Feb; 34(2):215-20.
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Gévry N, Chan HM, Laflamme L, Livingston DM, Gaudreau L. p21 transcription is regulated by differential localization of histone H2A.Z. Genes Dev. 2007 Aug 01; 21(15):1869-81.
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Pageau GJ, Hall LL, Ganesan S, Livingston DM, Lawrence JB. The disappearing Barr body in breast and ovarian cancers. Nat Rev Cancer. 2007 08; 7(8):628-33.
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Sobhian B, Shao G, Lilli DR, Culhane AC, Moreau LA, Xia B, Livingston DM, Greenberg RA. RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science. 2007 May 25; 316(5828):1198-202.
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Tischkowitz M, Xia B, Sabbaghian N, Reis-Filho JS, Hamel N, Li G, van Beers EH, Li L, Khalil T, Quenneville LA, Omeroglu A, Poll A, Lepage P, Wong N, Nederlof PM, Ashworth A, Tonin PN, Narod SA, Livingston DM, Foulkes WD. Analysis of PALB2/FANCN-associated breast cancer families. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6788-93.
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Silver DP, Dimitrov SD, Feunteun J, Gelman R, Drapkin R, Lu SD, Shestakova E, Velmurugan S, Denunzio N, Dragomir S, Mar J, Liu X, Rottenberg S, Jonkers J, Ganesan S, Livingston DM. Further evidence for BRCA1 communication with the inactive X chromosome. Cell. 2007 Mar 09; 128(5):991-1002.
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Erkko H, Xia B, Nikkilä J, Schleutker J, Syrjäkoski K, Mannermaa A, Kallioniemi A, Pylkäs K, Karppinen SM, Rapakko K, Miron A, Sheng Q, Li G, Mattila H, Bell DW, Haber DA, Grip M, Reiman M, Jukkola-Vuorinen A, Mustonen A, Kere J, Aaltonen LA, Kosma VM, Kataja V, Soini Y, Drapkin RI, Livingston DM, Winqvist R. A recurrent mutation in PALB2 in Finnish cancer families. Nature. 2007 Mar 15; 446(7133):316-9.
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Xia B, Dorsman JC, Ameziane N, de Vries Y, Rooimans MA, Sheng Q, Pals G, Errami A, Gluckman E, Llera J, Wang W, Livingston DM, Joenje H, de Winter JP. Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. Nat Genet. 2007 Feb; 39(2):159-61.
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Joukov V, Groen AC, Prokhorova T, Gerson R, White E, Rodriguez A, Walter JC, Livingston DM. The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly. Cell. 2006 Nov 03; 127(3):539-52.
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Sifri ZC, Homnick AT, Vaynman A, Lavery R, Liao W, Mohr A, Hauser CJ, Manniker A, Livingston D. A prospective evaluation of the value of repeat cranial computed tomography in patients with minimal head injury and an intracranial bleed. J Trauma. 2006 Oct; 61(4):862-7.
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Xia B, Sheng Q, Nakanishi K, Ohashi A, Wu J, Christ N, Liu X, Jasin M, Couch FJ, Livingston DM. Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol Cell. 2006 Jun 23; 22(6):719-29.
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Richardson AL, Wang ZC, De Nicolo A, Lu X, Brown M, Miron A, Liao X, Iglehart JD, Livingston DM, Ganesan S. X chromosomal abnormalities in basal-like human breast cancer. Cancer Cell. 2006 Feb; 9(2):121-32.
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Greenberg RA, Sobhian B, Pathania S, Cantor SB, Nakatani Y, Livingston DM. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes Dev. 2006 Jan 01; 20(1):34-46.
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Muljo SA, Ansel KM, Kanellopoulou C, Livingston DM, Rao A, Rajewsky K. Aberrant T cell differentiation in the absence of Dicer. J Exp Med. 2005 Jul 18; 202(2):261-9.
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Elshamy WM, Livingston DM. Promoter usage of BRCA1-IRIS. Nat Cell Biol. 2005 Apr; 7(4):326.
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Samuelson AV, Narita M, Chan HM, Jin J, de Stanchina E, McCurrach ME, Narita M, Fuchs M, Livingston DM, Lowe SW. p400 is required for E1A to promote apoptosis. J Biol Chem. 2005 Jun 10; 280(23):21915-23.
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Kanellopoulou C, Muljo SA, Kung AL, Ganesan S, Drapkin R, Jenuwein T, Livingston DM, Rajewsky K. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 2005 Feb 15; 19(4):489-501.
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Chan HM, Narita M, Lowe SW, Livingston DM. The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway. Genes Dev. 2005 Jan 15; 19(2):196-201.
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Ganesan S, Richardson AL, Wang ZC, Iglehart JD, Miron A, Feunteun J, Silver D, Livingston DM. Abnormalities of the inactive X chromosome are a common feature of BRCA1 mutant and sporadic basal-like breast cancer. Cold Spring Harb Symp Quant Biol. 2005; 70:93-7.
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ElShamy WM, Livingston DM. Identification of BRCA1-IRIS, a BRCA1 locus product. Nat Cell Biol. 2004 Oct; 6(10):954-67.
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Kung AL, Zabludoff SD, France DS, Freedman SJ, Tanner EA, Vieira A, Cornell-Kennon S, Lee J, Wang B, Wang J, Memmert K, Naegeli HU, Petersen F, Eck MJ, Bair KW, Wood AW, Livingston DM. Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway. Cancer Cell. 2004 Jul; 6(1):33-43.
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Wu X, Avni D, Chiba T, Yan F, Zhao Q, Lin Y, Heng H, Livingston D. SV40 T antigen interacts with Nbs1 to disrupt DNA replication control. Genes Dev. 2004 Jun 01; 18(11):1305-16.
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Taubert S, Gorrini C, Frank SR, Parisi T, Fuchs M, Chan HM, Livingston DM, Amati B. E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1. Mol Cell Biol. 2004 May; 24(10):4546-56.
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Cantor S, Drapkin R, Zhang F, Lin Y, Han J, Pamidi S, Livingston DM. The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations. Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8):2357-62.
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Livingston DM. EMSY, a BRCA-2 partner in crime. Nat Med. 2004 Feb; 10(2):127-8.
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Ganesan S, Silver DP, Drapkin R, Greenberg R, Feunteun J, Livingston DM. Association of BRCA1 with the inactive X chromosome and XIST RNA. Philos Trans R Soc Lond B Biol Sci. 2004 Jan 29; 359(1441):123-8.
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Sheperd RS, Ziccardi VB, Livingston D, Lavery R. Trauma from tire and rim explosions: A retrospective analysis. J Oral Maxillofac Surg. 2004 Jan; 62(1):36-8.
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Cable PL, Wilson CA, Calzone FJ, Rauscher FJ, Scully R, Livingston DM, Li L, Blackwell CB, Futreal PA, Afshari CA. Novel consensus DNA-binding sequence for BRCA1 protein complexes. Mol Carcinog. 2003 Oct; 38(2):85-96.
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Avni D, Yang H, Martelli F, Hofmann F, ElShamy WM, Ganesan S, Scully R, Livingston DM. Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage. Mol Cell. 2003 Sep; 12(3):735-46.
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Frank SR, Parisi T, Taubert S, Fernandez P, Fuchs M, Chan HM, Livingston DM, Amati B. MYC recruits the TIP60 histone acetyltransferase complex to chromatin. EMBO Rep. 2003 Jun; 4(6):575-80.
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Grossman SR, Deato ME, Brignone C, Chan HM, Kung AL, Tagami H, Nakatani Y, Livingston DM. Polyubiquitination of p53 by a ubiquitin ligase activity of p300. Science. 2003 Apr 11; 300(5617):342-4.
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Song X, Mohr AM, Rameshwar P, Anjaria D, Fekete Z, Hauser CJ, Livingston DH. Delayed differentiation of HL-60 cells following exposure to hypoxia. J Surg Res. 2002 Dec; 108(2):243-9.
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Ganesan S, Silver DP, Greenberg RA, Avni D, Drapkin R, Miron A, Mok SC, Randrianarison V, Brodie S, Salstrom J, Rasmussen TP, Klimke A, Marrese C, Marahrens Y, Deng CX, Feunteun J, Livingston DM. BRCA1 supports XIST RNA concentration on the inactive X chromosome. Cell. 2002 Nov 01; 111(3):393-405.
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Rebel VI, Kung AL, Tanner EA, Yang H, Bronson RT, Livingston DM. Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):14789-94.
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Dahme T, Wood J, Livingston DM, Gaubatz S. Two different E2F6 proteins generated by alternative splicing and internal translation initiation. Eur J Biochem. 2002 Oct; 269(20):5030-6.
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Storre J, Elsässer HP, Fuchs M, Ullmann D, Livingston DM, Gaubatz S. Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2f6. EMBO Rep. 2002 Jul; 3(7):695-700.
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Bassing CH, Chua KF, Sekiguchi J, Suh H, Whitlow SR, Fleming JC, Monroe BC, Ciccone DN, Yan C, Vlasakova K, Livingston DM, Ferguson DO, Scully R, Alt FW. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8173-8.
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Ogawa H, Ishiguro K, Gaubatz S, Livingston DM, Nakatani Y. A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. Science. 2002 May 10; 296(5570):1132-6.
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Yang H, Williams BO, Hinds PW, Shih TS, Jacks T, Bronson RT, Livingston DM. Tumor suppression by a severely truncated species of retinoblastoma protein. Mol Cell Biol. 2002 May; 22(9):3103-10.
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Freedman SJ, Sun ZY, Poy F, Kung AL, Livingston DM, Wagner G, Eck MJ. Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha. Proc Natl Acad Sci U S A. 2002 Apr 16; 99(8):5367-72.
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Kaul S, Homnick A, Livingston D. Intrapancreatic bile duct injury: case report. J Trauma. 2002 Apr; 52(4):786-8.
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Joo WS, Jeffrey PD, Cantor SB, Finnin MS, Livingston DM, Pavletich NP. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev. 2002 Mar 01; 16(5):583-93.
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Qian J, Ramroop K, McLeod A, Bandari P, Livingston DH, Harrison JS, Rameshwar P. Induction of hypoxia-inducible factor-1alpha and activation of caspase-3 in hypoxia-reoxygenated bone marrow stroma is negatively regulated by the delayed production of substance P. J Immunol. 2001 Oct 15; 167(8):4600-8.
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Joukov V, Chen J, Fox EA, Green JB, Livingston DM. Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development. Proc Natl Acad Sci U S A. 2001 Oct 09; 98(21):12078-83.
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Fuchs M, Gerber J, Drapkin R, Sif S, Ikura T, Ogryzko V, Lane WS, Nakatani Y, Livingston DM. The p400 complex is an essential E1A transformation target. Cell. 2001 Aug 10; 106(3):297-307.
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Wu JC, Livingston DH, Hauser CJ, Deitch EA, Rameshwar P. Trauma inhibits erythroid burst-forming unit and granulocyte-monocyte colony-forming unit growth through the production of TGF-beta1 by bone marrow stroma. Ann Surg. 2001 Aug; 234(2):224-32.
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Silver DP, Livingston DM. Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity. Mol Cell. 2001 Jul; 8(1):233-43.
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Ranganathan V, Heine WF, Ciccone DN, Rudolph KL, Wu X, Chang S, Hai H, Ahearn IM, Livingston DM, Resnick I, Rosen F, Seemanova E, Jarolim P, DePinho RA, Weaver DT. Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit. Curr Biol. 2001 Jun 26; 11(12):962-6.
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Mullen AC, High FA, Hutchins AS, Lee HW, Villarino AV, Livingston DM, Kung AL, Cereb N, Yao TP, Yang SY, Reiner SL. Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science. 2001 Jun 08; 292(5523):1907-10.
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Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell. 2001 Apr 06; 105(1):149-60.
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Livingston DM. Cancer: Chromosome defects in the colon. Nature. 2001 Mar 29; 410(6828):536-7.
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Martelli F, Hamilton T, Silver DP, Sharpless NE, Bardeesy N, Rokas M, DePinho RA, Livingston DM, Grossman SR. p19ARF targets certain E2F species for degradation. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4455-60.
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Livingston DM, Shivdasani R. Toward mechanism-based cancer care. JAMA. 2001 Feb 07; 285(5):588-93.
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Gaubatz S, Lees JA, Lindeman GJ, Livingston DM. E2F4 is exported from the nucleus in a CRM1-dependent manner. Mol Cell Biol. 2001 Feb; 21(4):1384-92.
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Tibbetts RS, Cortez D, Brumbaugh KM, Scully R, Livingston D, Elledge SJ, Abraham RT. Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Genes Dev. 2000 Dec 01; 14(23):2989-3002.
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Kung AL, Wang S, Klco JM, Kaelin WG, Livingston DM. Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med. 2000 Dec; 6(12):1335-40.
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Scully R, Livingston DM. In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature. 2000 Nov 23; 408(6811):429-32.
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Eid JE, Kung AL, Scully R, Livingston DM. p300 interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion. Cell. 2000 Sep 15; 102(6):839-48.
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Gaubatz S, Lindeman GJ, Ishida S, Jakoi L, Nevins JR, Livingston DM, Rempel RE. E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control. Mol Cell. 2000 Sep; 6(3):729-35.
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Ireland MJ, Reinke SS, Livingston DM. The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast. Genetics. 2000 Aug; 155(4):1657-65.
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Wu X, Petrini JH, Heine WF, Weaver DT, Livingston DM, Chen J. Independence of R/M/N focus formation and the presence of intact BRCA1. Science. 2000 Jul 07; 289(5476):11.
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Wu X, Ranganathan V, Weisman DS, Heine WF, Ciccone DN, O'Neill TB, Crick KE, Pierce KA, Lane WS, Rathbun G, Livingston DM, Weaver DT. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature. 2000 May 25; 405(6785):477-82.
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Mihich E, Livingston D. Eleventh annual Pezcoller Symposium: molecular horizons in cancer therapeutics. Cancer Res. 2000 Feb 01; 60(3):768-73.
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Kung AL, Rebel VI, Bronson RT, Ch'ng LE, Sieff CA, Livingston DM, Yao TP. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev. 2000 Feb 01; 14(3):272-7.
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Wu X, Rathbun G, Lane WS, Weaver DT, Livingston DM. Interactions of the Nijmegen breakage syndrome protein with ATM and BRCA1. Cold Spring Harb Symp Quant Biol. 2000; 65:535-45.
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Scully R, Ganesan S, Vlasakova K, Chen J, Socolovsky M, Livingston DM. Genetic analysis of BRCA1 function in a defined tumor cell line. Mol Cell. 1999 Dec; 4(6):1093-9.
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Leung MK, Jones T, Michels CL, Livingston DM, Bhattacharya S. Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1. Genomics. 1999 Nov 01; 61(3):307-13.
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Asleson EN, Okagaki RJ, Livingston DM. A core activity associated with the N terminus of the yeast RAD52 protein is revealed by RAD51 overexpression suppression of C-terminal rad52 truncation alleles. Genetics. 1999 Oct; 153(2):681-92.
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Schweitzer JK, Livingston DM. The effect of DNA replication mutations on CAG tract stability in yeast. Genetics. 1999 Jul; 152(3):953-63.
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Chen JJ, Silver D, Cantor S, Livingston DM, Scully R. BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway. Cancer Res. 1999 Apr 01; 59(7 Suppl):1752s-1756s.
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Martelli F, Livingston DM. Regulation of endogenous E2F1 stability by the retinoblastoma family proteins. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):2858-63.
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Wilson CA, Ramos L, Villaseñor MR, Anders KH, Press MF, Clarke K, Karlan B, Chen JJ, Scully R, Livingston D, Zuch RH, Kanter MH, Cohen S, Calzone FJ, Slamon DJ. Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas. Nat Genet. 1999 Feb; 21(2):236-40.
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Bhattacharya S, Michels CL, Leung MK, Arany ZP, Kung AL, Livingston DM. Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes Dev. 1999 Jan 01; 13(1):64-75.
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Wang ZM, Yang H, Livingston DM. Endogenous E2F-1 promotes timely G0 exit of resting mouse embryo fibroblasts. Proc Natl Acad Sci U S A. 1998 Dec 22; 95(26):15583-6.
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Grossman SR, Perez M, Kung AL, Joseph M, Mansur C, Xiao ZX, Kumar S, Howley PM, Livingston DM. p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol Cell. 1998 Oct; 2(4):405-15.
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Chen J, Silver DP, Walpita D, Cantor SB, Gazdar AF, Tomlinson G, Couch FJ, Weber BL, Ashley T, Livingston DM, Scully R. Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. Mol Cell. 1998 Sep; 2(3):317-28.
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Gaubatz S, Wood JG, Livingston DM. Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9190-5.
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Maurer DJ, O'Callaghan BL, Livingston DM. Mapping the polarity of changes that occur in interrupted CAG repeat tracts in yeast. Mol Cell Biol. 1998 Aug; 18(8):4597-604.
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Kawasaki H, Eckner R, Yao TP, Taira K, Chiu R, Livingston DM, Yokoyama KK. Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation. Nature. 1998 May 21; 393(6682):284-9.
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Yao TP, Oh SP, Fuchs M, Zhou ND, Ch'ng LE, Newsome D, Bronson RT, Li E, Livingston DM, Eckner R. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell. 1998 May 01; 93(3):361-72.
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Lindeman GJ, Dagnino L, Gaubatz S, Xu Y, Bronson RT, Warren HB, Livingston DM. A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targeting. Genes Dev. 1998 Apr 15; 12(8):1092-8.
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Nguyen MM, Livingston DM. The effect of a suppressed rad52 mutation on the suppression of rad6 by srs2. Yeast. 1997 Sep 15; 13(11):1059-64.
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Scully R, Chen J, Ochs RL, Keegan K, Hoekstra M, Feunteun J, Livingston DM. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell. 1997 Aug 08; 90(3):425-35.
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Nguyen MM, Livingston DM. Cold-sensitive rad52 alleles of yeast. Curr Genet. 1997 Aug; 32(2):100-7.
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Lill NL, Grossman SR, Ginsberg D, DeCaprio J, Livingston DM. Binding and modulation of p53 by p300/CBP coactivators. Nature. 1997 Jun 19; 387(6635):823-7.
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Scully R, Anderson SF, Chao DM, Wei W, Ye L, Young RA, Livingston DM, Parvin JD. BRCA1 is a component of the RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A. 1997 May 27; 94(11):5605-10.
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Livingston DM. Genetics is coming to oncology. JAMA. 1997 May 14; 277(18):1476-7.
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Lindeman GJ, Gaubatz S, Livingston DM, Ginsberg D. The subcellular localization of E2F-4 is cell-cycle dependent. Proc Natl Acad Sci U S A. 1997 May 13; 94(10):5095-100.
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Livingston DM. Cancer genetics and tumor suppressor genes. Sponsored by Cold Spring Harbor Laboratory--August 14-18, 1996. Biochim Biophys Acta. 1997 Apr 18; 1332(2):R25-31.
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Schweitzer JK, Livingston DM. Destabilization of CAG trinucleotide repeat tracts by mismatch repair mutations in yeast. Hum Mol Genet. 1997 Mar; 6(3):349-55.
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Norman J, Yang J, Fink G, Carter G, Ku G, Denham W, Livingston D. Severity and mortality of experimental pancreatitis are dependent on interleukin-1 converting enzyme (ICE). J Interferon Cytokine Res. 1997 Feb; 17(2):113-8.
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Huang LE, Ho V, Arany Z, Krainc D, Galson D, Tendler D, Livingston DM, Bunn HF. Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors. Kidney Int. 1997 Feb; 51(2):548-52.
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Scully R, Chen J, Plug A, Xiao Y, Weaver D, Feunteun J, Ashley T, Livingston DM. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell. 1997 Jan 24; 88(2):265-75.
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Lill NL, Tevethia MJ, Eckner R, Livingston DM, Modjtahedi N. p300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigen. J Virol. 1997 Jan; 71(1):129-37.
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Huang LE, Arany Z, Livingston DM, Bunn HF. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J Biol Chem. 1996 Dec 13; 271(50):32253-9.
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Maurer DJ, O'Callaghan BL, Livingston DM. Orientation dependence of trinucleotide CAG repeat instability in Saccharomyces cerevisiae. Mol Cell Biol. 1996 Dec; 16(12):6617-22.
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Hofmann F, Martelli F, Livingston DM, Wang Z. The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev. 1996 Dec 01; 10(23):2949-59.
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Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, Goldberg MA, Bunn HF, Livingston DM. An essential role for p300/CBP in the cellular response to hypoxia. Proc Natl Acad Sci U S A. 1996 Nov 12; 93(23):12969-73.
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Eckner R, Yao TP, Oldread E, Livingston DM. Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes Dev. 1996 Oct 01; 10(19):2478-90.
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Yao TP, Ku G, Zhou N, Scully R, Livingston DM. The nuclear hormone receptor coactivator SRC-1 is a specific target of p300. Proc Natl Acad Sci U S A. 1996 Oct 01; 93(20):10626-31.
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Bhattacharya S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston DM. Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature. 1996 Sep 26; 383(6598):344-7.
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Eckner R, Ludlow JW, Lill NL, Oldread E, Arany Z, Modjtahedi N, DeCaprio JA, Livingston DM, Morgan JA. Association of p300 and CBP with simian virus 40 large T antigen. Mol Cell Biol. 1996 Jul; 16(7):3454-64.
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Field SJ, Tsai FY, Kuo F, Zubiaga AM, Kaelin WG, Livingston DM, Orkin SH, Greenberg ME. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell. 1996 May 17; 85(4):549-61.
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Xiao ZX, Ginsberg D, Ewen M, Livingston DM. Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases. Proc Natl Acad Sci U S A. 1996 May 14; 93(10):4633-7.
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Scully R, Ganesan S, Brown M, De Caprio JA, Cannistra SA, Feunteun J, Schnitt S, Livingston DM. Location of BRCA1 in human breast and ovarian cancer cells. Science. 1996 Apr 05; 272(5258):123-6.
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Hofmann F, Livingston DM. Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit. Genes Dev. 1996 Apr 01; 10(7):851-61.
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Livingston DM. Cancer genes: functional aspects. Meeting report. Biochim Biophys Acta. 1996 Mar 18; 1242(3):211-6.
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Krek W, Xu G, Livingston DM. Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell. 1995 Dec 29; 83(7):1149-58.
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Wydner KL, Bhattacharya S, Eckner R, Lawrence JB, Livingston DM. Localization of human CREB-binding protein gene (CREBBP) to 16p13.2-p13.3 by fluorescence in situ hybridization. Genomics. 1995 Nov 20; 30(2):395-6.
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Kaytor MD, Livingston DM. GSG1, a yeast gene required for sporulation. Yeast. 1995 Sep 30; 11(12):1147-55.
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Kaytor MD, Nguyen M, Livingston DM. The complexity of the interaction between RAD52 and SRS2. Genetics. 1995 Aug; 140(4):1441-2.
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Kitabayashi I, Eckner R, Arany Z, Chiu R, Gachelin G, Livingston DM, Yokoyama KK. Phosphorylation of the adenovirus E1A-associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cells. EMBO J. 1995 Jul 17; 14(14):3496-509.
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Xiao ZX, Chen J, Levine AJ, Modjtahedi N, Xing J, Sellers WR, Livingston DM. Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature. 1995 Jun 22; 375(6533):694-8.
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Missero C, Calautti E, Eckner R, Chin J, Tsai LH, Livingston DM, Dotto GP. Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc Natl Acad Sci U S A. 1995 Jun 06; 92(12):5451-5.
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Lee JS, Galvin KM, See RH, Eckner R, Livingston D, Moran E, Shi Y. Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300. Genes Dev. 1995 May 15; 9(10):1188-98.
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Vairo G, Livingston DM, Ginsberg D. Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. Genes Dev. 1995 Apr 01; 9(7):869-81.
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Arany Z, Newsome D, Oldread E, Livingston DM, Eckner R. A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Nature. 1995 Mar 02; 374(6517):81-4.
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Xu G, Livingston DM, Krek W. Multiple members of the E2F transcription factor family are the products of oncogenes. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1357-61.
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Qin XQ, Livingston DM, Ewen M, Sellers WR, Arany Z, Kaelin WG. The transcription factor E2F-1 is a downstream target of RB action. Mol Cell Biol. 1995 Feb; 15(2):742-55.
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Ginsberg D, Vairo G, Chittenden T, Xiao ZX, Xu G, Wydner KL, DeCaprio JA, Lawrence JB, Livingston DM. E2F-4, a new member of the E2F transcription factor family, interacts with p107. Genes Dev. 1994 Nov 15; 8(22):2665-79.
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Qin XQ, Livingston DM, Kaelin WG, Adams PD. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci U S A. 1994 Nov 08; 91(23):10918-22.
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Ranum LP, Schut LJ, Lundgren JK, Orr HT, Livingston DM. Spinocerebellar ataxia type 5 in a family descended from the grandparents of President Lincoln maps to chromosome 11. Nat Genet. 1994 Nov; 8(3):280-4.
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Wang WB, Bikel I, Marsilio E, Newsome D, Livingston DM. Transrepression of RNA polymerase II promoters by the simian virus 40 small t antigen. J Virol. 1994 Oct; 68(10):6180-7.
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Kaytor MD, Livingston DM. Saccharomyces cerevisiae RAD52 alleles temperature-sensitive for the repair of DNA double-strand breaks. Genetics. 1994 Aug; 137(4):933-44.
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Krek W, Ewen ME, Shirodkar S, Arany Z, Kaelin WG, Livingston DM. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell. 1994 Jul 15; 78(1):161-72.
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Arany Z, Sellers WR, Livingston DM, Eckner R. E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators. Cell. 1994 Jun 17; 77(6):799-800.
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Eckner R, Ewen ME, Newsome D, Gerdes M, DeCaprio JA, Lawrence JB, Livingston DM. Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 1994 Apr 15; 8(8):869-84.
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Eckner R, Arany Z, Ewen M, Sellers W, Livingston DM. The adenovirus E1A-associated 300-kD protein exhibits properties of a transcriptional coactivator and belongs to an evolutionarily conserved family. Cold Spring Harb Symp Quant Biol. 1994; 59:85-95.
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Krek W, Livingston DM, Shirodkar S. Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science. 1993 Dec 03; 262(5139):1557-60.
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Frazee RW, Livingston DM, LaPorte DC, Lipscomb JD. Cloning, sequencing, and expression of the Pseudomonas putida protocatechuate 3,4-dioxygenase genes. J Bacteriol. 1993 Oct; 175(19):6194-202.
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Ewen ME, Sluss HK, Whitehouse LL, Livingston DM. TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell. 1993 Sep 24; 74(6):1009-20.
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Livingston DM, Kaelin W, Chittenden T, Qin X. Structural and functional contributions to the G1 blocking action of the retinoblastoma protein. (the 1992 Gordon Hamilton Fairley Memorial Lecture). Br J Cancer. 1993 Aug; 68(2):264-8.
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Zhu L, van den Heuvel S, Helin K, Fattaey A, Ewen M, Livingston D, Dyson N, Harlow E. Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. Genes Dev. 1993 Jul; 7(7A):1111-25.
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Chittenden T, Livingston DM, DeCaprio JA. Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F. Mol Cell Biol. 1993 Jul; 13(7):3975-83.
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Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato J, Livingston DM. Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell. 1993 May 07; 73(3):487-97.
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Ludlow JW, Glendening CL, Livingston DM, DeCarprio JA. Specific enzymatic dephosphorylation of the retinoblastoma protein. Mol Cell Biol. 1993 Jan; 13(1):367-72.
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Qin XQ, Chittenden T, Livingston DM, Kaelin WG. Identification of a growth suppression domain within the retinoblastoma gene product. Genes Dev. 1992 Jun; 6(6):953-64.
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Livingston D, Mihich E. Third annual Pezcoller symposium: tumor suppressor genes. Cancer Res. 1992 Jun 01; 52(11):3246-9.
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DeCaprio JA, Furukawa Y, Ajchenbaum F, Griffin JD, Livingston DM. The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression. Proc Natl Acad Sci U S A. 1992 Mar 01; 89(5):1795-8.
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Perentesis JP, Phan LD, Gleason WB, LaPorte DC, Livingston DM, Bodley JW. Saccharomyces cerevisiae elongation factor 2. Genetic cloning, characterization of expression, and G-domain modeling. J Biol Chem. 1992 Jan 15; 267(2):1190-7.
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Shirodkar S, Ewen M, DeCaprio JA, Morgan J, Livingston DM, Chittenden T. The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell. 1992 Jan 10; 68(1):157-66.
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Ewen ME, Faha B, Harlow E, Livingston DM. Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins. Science. 1992 Jan 03; 255(5040):85-7.
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Faha B, Ewen ME, Tsai LH, Livingston DM, Harlow E. Interaction between human cyclin A and adenovirus E1A-associated p107 protein. Science. 1992 Jan 03; 255(5040):87-90.
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Livingston DM. Functional analysis of the retinoblastoma gene product and of RB-SV40 T antigen complexes. Cancer Surv. 1992; 12:153-60.
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Marsilio E, Cheng SH, Schaffhausen B, Paucha E, Livingston DM. The T/t common region of simian virus 40 large T antigen contains a distinct transformation-governing sequence. J Virol. 1991 Oct; 65(10):5647-52.
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Ewen ME, Xing YG, Lawrence JB, Livingston DM. Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell. 1991 Sep 20; 66(6):1155-64.
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Chittenden T, Livingston DM, Kaelin WG. The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell. 1991 Jun 14; 65(6):1073-82.
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Dornfeld KJ, Livingston DM. Effects of controlled RAD52 expression on repair and recombination in Saccharomyces cerevisiae. Mol Cell Biol. 1991 Apr; 11(4):2013-7.
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Howley PM, Levine AJ, Li FP, Livingston DM, Rabson AS. Lack of SV40 DNA in tumors from scientists working with SV40 virus. N Engl J Med. 1991 Feb 14; 324(7):494.
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Kaelin WG, Pallas DC, DeCaprio JA, Kaye FJ, Livingston DM. Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell. 1991 Feb 08; 64(3):521-32.
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Laiho M, Rönnstrand L, Heino J, Decaprio JA, Ludlow JW, Livingston DM, Massagué J. Control of junB and extracellular matrix protein expression by transforming growth factor-beta 1 is independent of simian virus 40 T antigen-sensitive growth-sensitive growth-inhibitory events. Mol Cell Biol. 1991 Feb; 11(2):972-8.
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Chittenden T, Livingston DM, Kaelin WG. RB associates with an E2F-like, sequence-specific DNA-binding protein. Cold Spring Harb Symp Quant Biol. 1991; 56:187-95.
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Montano X, Millikan R, Milhaven JM, Newsom DA, Ludlow JW, Arthur AK, Fanning E, Bikel I, Livingston DM. Simian virus 40 small tumor antigen and an amino-terminal domain of large tumor antigen share a common transforming function. Proc Natl Acad Sci U S A. 1990 Oct; 87(19):7448-52.
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Laiho M, DeCaprio JA, Ludlow JW, Livingston DM, Massagué J. Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation. Cell. 1990 Jul 13; 62(1):175-85.
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Kaelin WG, Ewen ME, Livingston DM. Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product. Mol Cell Biol. 1990 Jul; 10(7):3761-9.
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Furukawa Y, DeCaprio JA, Freedman A, Kanakura Y, Nakamura M, Ernst TJ, Livingston DM, Griffin JD. Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells. Proc Natl Acad Sci U S A. 1990 Apr; 87(7):2770-4.
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Ludlow JW, Shon J, Pipas JM, Livingston DM, DeCaprio JA. The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T. Cell. 1990 Feb 09; 60(3):387-96.
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DeCaprio JA, Ludlow JW, Lynch D, Furukawa Y, Griffin J, Piwnica-Worms H, Huang CM, Livingston DM. The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell. 1989 Sep 22; 58(6):1085-95.
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Ewen ME, Ludlow JW, Marsilio E, DeCaprio JA, Millikan RC, Cheng SH, Paucha E, Livingston DM. An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120. Cell. 1989 Jul 28; 58(2):257-67.
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Ludlow JW, DeCaprio JA, Huang CM, Lee WH, Paucha E, Livingston DM. SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family. Cell. 1989 Jan 13; 56(1):57-65.
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Livingston DM, DeCaprio JA, Ludlow JW. Does the product of the RB-1 locus have a cell cycle regulatory function? Princess Takamatsu Symp. 1989; 20:187-90.
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Loeken M, Bikel I, Livingston DM, Brady J. trans-activation of RNA polymerase II and III promoters by SV40 small t antigen. Cell. 1988 Dec 23; 55(6):1171-7.
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Perentesis JP, Genbauffe FS, Veldman SA, Galeotti CL, Livingston DM, Bodley JW, Murphy JR. Expression of diphtheria toxin fragment A and hormone-toxin fusion proteins in toxin-resistant yeast mutants. Proc Natl Acad Sci U S A. 1988 Nov; 85(22):8386-90.
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Kim KW, Kamerud JQ, Livingston DM, Roon RJ. Asparaginase II of Saccharomyces cerevisiae. Characterization of the ASP3 gene. J Biol Chem. 1988 Aug 25; 263(24):11948-53.
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Murphy CI, Weiner B, Bikel I, Piwnica-Worms H, Bradley MK, Livingston DM. Purification and functional properties of simian virus 40 large and small T antigens overproduced in insect cells. J Virol. 1988 Aug; 62(8):2951-9.
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DeCaprio JA, Ludlow JW, Figge J, Shew JY, Huang CM, Lee WH, Marsilio E, Paucha E, Livingston DM. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell. 1988 Jul 15; 54(2):275-83.
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Ahn BY, Dornfeld KJ, Fagrelius TJ, Livingston DM. Effect of limited homology on gene conversion in a Saccharomyces cerevisiae plasmid recombination system. Mol Cell Biol. 1988 Jun; 8(6):2442-8.
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Figge J, Wright C, Collins CJ, Roberts TM, Livingston DM. Stringent regulation of stably integrated chloramphenicol acetyl transferase genes by E. coli lac repressor in monkey cells. Cell. 1988 Mar 11; 52(5):713-22.
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Levene RB, Booyse FM, Chediak J, Zimmerman TS, Livingston DM, Lynch DC. Expression of abnormal von Willebrand factor by endothelial cells from a patient with type IIA von Willebrand disease. Proc Natl Acad Sci U S A. 1987 Sep; 84(18):6550-4.
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Collins CJ, Underdahl JP, Levene RB, Ravera CP, Morin MJ, Dombalagian MJ, Ricca G, Livingston DM, Lynch DC. Molecular cloning of the human gene for von Willebrand factor and identification of the transcription initiation site. Proc Natl Acad Sci U S A. 1987 Jul; 84(13):4393-7.
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Livingston DM. George Khoury (1943-1987). Cell. 1987 Jun 05; 49(5):577.
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Brown M, Figge J, Hansen U, Wright C, Jeang KT, Khoury G, Livingston DM, Roberts TM. lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells. Cell. 1987 Jun 05; 49(5):603-12.
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Bradley MK, Smith TF, Lathrop RH, Livingston DM, Webster TA. Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens. Proc Natl Acad Sci U S A. 1987 Jun; 84(12):4026-30.
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Livingston DM, Bradley MK. The simian virus 40 large T antigen. A lot packed into a little. Mol Biol Med. 1987 Apr; 4(2):63-80.
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Bikel I, Montano X, Agha ME, Brown M, McCormack M, Boltax J, Livingston DM. SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen. Cell. 1987 Jan 30; 48(2):321-30.
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Ahn BY, Livingston DM. Mitotic gene conversion lengths, coconversion patterns, and the incidence of reciprocal recombination in a Saccharomyces cerevisiae plasmid system. Mol Cell Biol. 1986 Nov; 6(11):3685-93.
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Brown M, McCormack M, Zinn KG, Farrell MP, Bikel I, Livingston DM. A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth. J Virol. 1986 Oct; 60(1):290-3.
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Murphy CI, Bikel I, Livingston DM. Cellular proteins which can specifically associate with simian virus 40 small t antigen. J Virol. 1986 Sep; 59(3):692-702.
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Norrander JM, Fagrelius TJ, Livingston DM. Accumulation of single strand interruptions within the yeast 2 microns DNA plasmid during replication in a DNA ligase mutant. Mol Gen Genet. 1986 Jun; 203(3):406-9.
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Bikel I, Mamon H, Brown EL, Boltax J, Agha M, Livingston DM. The t-unique coding domain is important to the transformation maintenance function of the simian virus 40 small t antigen. Mol Cell Biol. 1986 Apr; 6(4):1172-8.
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Chen JY, Bodley JW, Livingston DM. Diphtheria toxin-resistant mutants of Saccharomyces cerevisiae. Mol Cell Biol. 1985 Dec; 5(12):3357-60.
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Tenen DG, Haines LL, Hansen UM, Martin RG, Livingston DM. Formation of a cruciform structure at the simian virus 40 replication origin abolishes T-antigen binding to the origin in vitro. J Virol. 1985 Oct; 56(1):293-7.
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Lynch DC, Zimmerman TS, Collins CJ, Brown M, Morin MJ, Ling EH, Livingston DM. Molecular cloning of cDNA for human von Willebrand factor: authentication by a new method. Cell. 1985 May; 41(1):49-56.
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Bradley MK, Hudson J, Villanueva MS, Livingston DM. Specific in vitro adenylylation of the simian virus 40 large tumor antigen. Proc Natl Acad Sci U S A. 1984 Nov; 81(21):6574-8.
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Ellman M, Bikel I, Figge J, Roberts T, Schlossman R, Livingston DM. Localization of the simian virus 40 small t antigen in the nucleus and cytoplasm of monkey and mouse cells. J Virol. 1984 May; 50(2):623-8.
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Lynch DC, Zimmerman TS, Kirby EP, Livingston DM. Subunit composition of oligomeric human von Willebrand factor. J Biol Chem. 1983 Nov 10; 258(21):12757-60.
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Tenen DG, Livingston DM, Wang SS, Martin RG. Effect of a stem-loop structure within the SV40 replication origin upon SV40 T antigen binding to origin region sequences. Cell. 1983 Sep; 34(2):629-39.
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Tenen DG, Taylor TS, Haines LL, Bradley MK, Martin RG, Livingston DM. Binding of simian virus 40 large T antigen from virus-infected monkey cells to wild-type and mutant viral replication origins. J Mol Biol. 1983 Aug 25; 168(4):791-808.
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Lynch DC, Williams R, Zimmerman TS, Kirby EP, Livingston DM. Biosynthesis of the subunits of factor VIIIR by bovine aortic endothelial cells. Proc Natl Acad Sci U S A. 1983 May; 80(9):2738-42.
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Bikel I, Roberts TM, Bladon MT, Green R, Amann E, Livingston DM. Purification of biologically active simian virus 40 small tumor antigen. Proc Natl Acad Sci U S A. 1983 Feb; 80(4):906-10.
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Livingston DM. A sequence of the yeast 2 micron DNA plasmid chromosome near the origin of replication is exposed to restriction endonuclease digestion. J Mol Biol. 1982 Sep 25; 160(3):397-410.
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Rubin H, Figge J, Bladon MT, Chen LB, Ellman M, Bikel I, Farrell M, Livingston DM. Role of small t antigen in the acute transforming activity of SV40. Cell. 1982 Sep; 30(2):469-80.
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Tenen DG, Haines LL, Livingston DM. Binding of an analog of the simian virus 40 T antigen to wild-type and mutant viral replication origins. J Mol Biol. 1982 May 25; 157(3):473-92.
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Murakami S, Bodley JW, Livingston DM. Saccharomyces cerevisiae spheroplasts are sensitive to the action of diphtheria toxin. Mol Cell Biol. 1982 May; 2(5):588-92.
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Bradley MK, Griffin JD, Livingston DM. Relationship of oligomerization to enzymatic and DNA-binding properties of the SV40 large T antigen. Cell. 1982 Jan; 28(1):125-34.
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Hansen U, Tenen DG, Livingston DM, Sharp PA. T antigen repression of SV40 early transcription from two promoters. Cell. 1981 Dec; 27(3 Pt 2):603-13.
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Kilton LJ, Bradley M, Mehta C, Livingston DM. Rapid and sensitive quantitative immunoassay for the large simian virus 40 T antigen. J Virol. 1981 May; 38(2):612-20.
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Glode LM, Kriegler MP, Livingston DM. Cysteine auxotrophy of human leukemic lymphoblasts is associated with decreased amounts of intracellular cystathionase protein. Biochemistry. 1981 Mar 03; 20(5):1306-11.
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Sigurdson DC, Gaarder ME, Livingston DM. Characterization of the transmission during cytoductant formation of the 2 micrometers DNA plasmid from Saccharomyces. Mol Gen Genet. 1981; 183(1):59-65.
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Spangler GJ, Griffin JD, Rubin H, Livingston DM. Identification and initial characterization of a new low-molecular-weight virus-encoded T antigen in a line of simian virus 40-transformed cells. J Virol. 1980 Nov; 36(2):488-98.
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Shalloway D, Kleinberger T, Livingston DM. Mapping of SV40 DNA replication origin region binding sites for the SV40 T antigen by protection against exonuclease III digestion. Cell. 1980 Jun; 20(2):411-22.
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Antman KH, Livingston DM. Intracellular neutralization of SV40 tumor antigens following microinjection of specific antibody. Cell. 1980 Mar; 19(3):627-35.
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Griffin JD, Spangler G, Livingston DM. Enzymatic activities associated with the SV40 large T antigen. Cold Spring Harb Symp Quant Biol. 1980; 44 Pt 1,:113-22.
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Roberts TM, Bikel I, Yocum RR, Livingston DM, Ptashne M. Synthesis of simian virus 40 t antigen in Escherichia coli. Proc Natl Acad Sci U S A. 1979 Nov; 76(11):5596-600.
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Griffin JD, Spangler G, Livingston DM. Protein kinase activity associated with simian virus 40 T antigen. Proc Natl Acad Sci U S A. 1979 Jun; 76(6):2610-4.
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Chang C, Martin RG, Livingston DM, Luborsky SW, Hu CP, Mora PT. Relationship between T-antigen and tumor-specific transplantation antigen in simian virus 40-transformed cells. J Virol. 1979 Jan; 29(1):69-75.
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Bikel I, Faibes D, Uren JR, Livingston DM. Immunologic analyses of mouse cystathionase in normal and leukemic cells. Biochemistry. 1978 Nov 28; 17(24):5181-7.
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Kriegler MP, Griffin JD, Livingston DM. Phenotypic complementation of the SV40 tsA mutant defect in viral DNA synthesis following microinjection of SV40 T antigen. Cell. 1978 Aug; 14(4):983-94.
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Griffin JD, Light S, Livingston DM. Measurements of the molecular size of the simian virus 40 large T antigen. J Virol. 1978 Jul; 27(1):218-26.
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Lazarus H, Barell EF, Krishan A, Livingston DM, Harris K, Schlossman SF, Chess L. Characterization of a unique cell line (LAZ 221) from human acute lymphocytic ("null" cell) leukemia. Cancer Res. 1978 May; 38(5):1362-7.
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Bikel I, Pavlatos TN, Livingston DM. Purification and subunit structure of mouse liver cystathionase. Arch Biochem Biophys. 1978 Feb; 186(1):168-74.
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Persico-DiLauro M, Martin RG, Livingston DM. Interaction of Simian Virus 40 chromatin with Simian Virus 40 T-antigen. J Virol. 1977 Nov; 24(2):451-60.
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Iglehart JK, York RM, Modest AP, Lazarus H, Livingston DM. Cystine requirement of continuous human lymphoid cell lines of normal and leukemic origin. J Biol Chem. 1977 Oct 25; 252(20):7184-91.
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Livingston DM, Kupfer DM. Control of Saccharomyces cerevisiae 2microN DNA replication by cell division cycle genes that control nuclear DNA replication. J Mol Biol. 1977 Oct 25; 116(2):249-60.
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Tenen DG, Garewal H, Haines LL, Hudson J, Woodard V, Light S, Livingston DM. Purification of simian virus 40 tumor antigen from a line of simian virus 40-transformed human cells. Proc Natl Acad Sci U S A. 1977 Sep; 74(9):3745-9.
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Livingston DM. Inheritance of the 2 micrometer m DNA plasmid from Saccharomyces. Genetics. 1977 May; 86(1):73-84.
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Tenen DG, Martin RG, Anderson J, Livingston DM. Biological and biochemical studies of cells transformed by simian virus 40 temperature-sensitive gene A mutants and A mutant revertants. J Virol. 1977 Apr; 22(1):210-8.
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Anderson JL, Martin RG, Chang C, Mora PT, Livingston DM. Nuclear preparations of SV40-transformed cells contain tumor-specific transplantation antigen activity. Virology. 1977 Jan; 76(1):420-5.
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Jessel D, Landau T, Hudson J, Lalor T, Tenen D, Livingston DM. Identification of regions of the SV40 genome which contain preferred SV40 T antigen-binding sites. Cell. 1976 Aug; 8(4):535-45.
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Livingston DM, Howard T, Spence C. Identification of infectious virions which are vesicular stomatitis virus pseudotypes of murine type C virus. Virology. 1976 Apr; 70(2):432-9.
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Livingston DM, Ferguson C, Gollogly R, Lazarus H. Accumulation of cystine auxotrophic thymocytes accompanying type C viral leukemogenesis in the mouse. Cell. 1976 Jan; 7(1):41-7.
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Tenen DG, Baygell P, Livingston DM. Thermolabile T (tumor) antigen from cells transformed by a temperature-sensitive mutant of simian virus 40. Proc Natl Acad Sci U S A. 1975 Nov; 72(11):4351-5.
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Jessel D, Hudson J, Landau T, Tenen D, Livingston DM. Interaction of partially purified simian virus 40 T antigen with circular viral DNA molecules. Proc Natl Acad Sci U S A. 1975 May; 72(5):1960-4.
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Livingston DM, Hinkle DC, Richardson CC. Deoxyribonucleic acid polymerase III of Escherichia coli. Purification and properties. J Biol Chem. 1975 Jan 25; 250(2):461-9.
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Livingston DM, Henderson IC, Hudson J. SV40 T antigen: partial purification and properties. Cold Spring Harb Symp Quant Biol. 1975; 39 Pt 1:283-9.
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Desai LS, Livingston DM. Studies on the type C viral replication defect in MSV-transformed rat nonproducer variant clones. Virology. 1974 Dec; 62(2):337-43.
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Henderson IC, Livingston DM. Partial purification and characterization of the SV40 T antigen. Cell. 1974 Sep; 3(1):65-70.
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Gallagher RE, Todaro GJ, Smith RG, Livingston DM, Gallo RC. Relationship between RNA-directed DNA polymerase (reverse transcriptase) from human acute leukemic blood cells and primate type-C viruses. Proc Natl Acad Sci U S A. 1974 Apr; 71(4):1309-13.
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Benveniste RE, Lieber MM, Livingston DM, Sherr CJ, Todaro GJ, Kalter SS. Infectious C-type virus isolated from a baboon placenta. Nature. 1974 Mar 01; 248(5443):17-20.
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Livingston DM, Serxner LE, Howk DJ, Hudson J, Todaro GJ. Characterization of a new murine cellular DNA polymerase. Proc Natl Acad Sci U S A. 1974 Jan; 71(1):57-62.
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Lieber MM, Benveniste RE, Livingston DM, Todaro GJ. Mammalian cells in culture frequently release type C viruses. Science. 1973 Oct 05; 182(4107):56-9.
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Todaro GJ, Benveniste RE, Lieber MM, Livingston DM. Infectious type C viruses released by normal cat embryo cells. Virology. 1973 Oct; 55(2):506-15.
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Lieber MM, Livingston DM, Todaro GJ. Superinduction of endogenous type C virus by 5-bromodeoxyuridine from transformed mouse clones. Science. 1973 Aug 03; 181(4098):443-4.
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Livingston DM, Todaro GJ. Endogenous type C virus from a cat cell clone with properties distinct from previously described feline type C virus. Virology. 1973 May; 53(1):142-51.
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Parks WP, Livingston DM, Todaro GJ, Benveniste RE, Scolnick EM. Radioimmunoassay of mammalian type C viral proteins. 3. Detection of viral antigen in normal murine cells and tissues. J Exp Med. 1973 Mar 01; 137(3):622-35.
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Livingston DM, Todaro GJ. Murine sarcoma virus-transformed nonproducer rat cell lines resistant to type C-virus infection. Intervirology. 1973; 1(5-6):329-37.
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Todaro GJ, Scolnick EM, Parks WP, Livingston DM, Aaronson SA. Detection of type C viruses in normal and transformed cells. Johns Hopkins Med J Suppl. 1973; 2:231-44.
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Livingston DM, Parks WP, Scolnick EM, Ross J. Affinity chromatography of avian type C viral reverse transcriptase: studies with Rous sarcoma virus transformed rat cells. Virology. 1972 Nov; 50(2):388-95.
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Scolnick EM, Parks WP, Livingston DM. Radioimmunoassay of mammalian type C viral proteins. I. Species specific reactions of murine and feline viruses. J Immunol. 1972 Sep; 109(3):570-7.
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Livingston DM, Scolnick EM, Parks WP, Todaro GT. Affinity chromatography of RNA-dependent DNA polymerase from RNA tumor viruses on a solid phase immunoadsorbent. Proc Natl Acad Sci U S A. 1972 Feb; 69(2):393-7.
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Vallee BL, Riordan JF, Johansen JT, Livingston DM. Spectro-chemical probes for protein conformation and function. Cold Spring Harb Symp Quant Biol. 1972; 36:517-31.
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Leder P, Bernardi A, Livingston D, Loyd B, Roufa D, Skogerson L. Protein biosynthesis: studies using synthetic and viral mRNAs. Cold Spring Harb Symp Quant Biol. 1969; 34:411-7.
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