James M. Cleary, MD, PhD

James M. Cleary, MD, PhD

Medical Oncology

Contact Information

Office Phone Number

617-632-6073

Fax

617-632-5370

Appointments

617-632-5929

Biography

James M. Cleary, MD, PhD

Researcher

Physician

Director, Clinical Research, Division of Gastrointestinal Oncology
Senior Physician
Associate Professor of Medicine, Harvard Medical School

Centers/Programs

Clinical Interests

Gastrointestinal malignancies, Phase 1 clinical trials

Board Certification

  • Internal Medicine, 2006
  • Medical Oncology, 2008

Fellowship

  • Dana-Farber Cancer Institute, Medical Oncology

Residency

  • Massachusetts General Hospital, Internal Medicine

Medical School

  • Albert Einstein Medical School

Research

    Early Drug Development, Gastrointestinal Malignancies, Translational Research

    My career is focused on phase 1 and proof-of-mechanism clinical trials that are testing new targeted therapies and novel therapeutic strategies. While I conduct trials appropriate for a broad range of solid tumors, I am particularly interested in new drug development for gastrointestinal malignancies. Currently, I am developing several protocols appropriate for specific molecularly defined patient cohorts, including those whose tumors are dependent on EGFR, mutant K-Ras and mutant B-Raf, respectively. I also interact with Dana-Farber translational researchers to understand and develop predictors of sensitivity and resistance to targeted agents that can be incorporated into patient selection for trials.

    Locations

    Location Avtar

    Dana-Farber Cancer Institute

    450 Brookline Avenue LG-GC12 Boston, MA 02215
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    Dana-Farber Cancer Institute

    Location Avtar

    Dana-Farber Cancer Institute

    450 Brookline Avenue LG-GC12 Boston, MA 02215
    Get Direction
    42.3374, -71.1082

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