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Lisa R. Diller, MD


Pediatric Hematology/Oncology

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Lisa R. Diller, MD americas top doctors

Physician

  • Vice Chair, Department of Pediatric Oncology, Dana-Farber Cancer Institute
  • Chief Medical Officer, Dana-Farber/Boston Children's Cancer and Blood Disorders Center
  • Director, David B. Perini Jr. Quality of Life Clinic for Childhood Cancer Survivors, Dana-Farber Cancer Institute
  • Institute Physician, Dana-Farber Cancer Institute
  • Attending Physician, Division of Hematology/Oncology, Department of Pediatrics, Boston Children's Hospital
  • Professor of Pediatrics, Harvard Medical School

Clinical Interests

  • Cancer predisposition
  • Global health
  • Late effects of pediatric cancer
  • Melanoma
  • Neuroblastoma
  • Retinoblastoma
  • Solid tumors
  • Wilms tumor

Contact Information

  • Appointments888-733-4662 (New Pediatric Patients)
    617-632-3270 (Established Pediatric Patients)
  • Fax617-582-9049

Bio

Dr. Lisa Diller is the Chief Medical Officer, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, and the Vice Chair, Department of Pediatric Oncology, Dana-Farber Cancer Institute. She is also the Director of the Perini Family Survivors Center and the David B. Perini Jr. Quality of Life Clinic at Dana-Farber. She is a Professor of Pediatrics at Harvard Medical School. Dr. Diller received a bachelor's degree from Harvard University and earned her medical degree from the University of California at San Diego. She was a resident at Boston Children's Hospital and did her subspecialty training at Dana-Farber/Boston Children's, where she has been on the faculty for over 20 years. Dr. Diller's research focuses on the late effects of treatment for childhood cancer and genetic cancer predisposition syndromes in childhood. In addition, she investigates novel treatments for pediatric solid tumors, particularly tumors that occur in infants and toddlers.

Board Certification:

  • Pediatric Hematology/Oncology
  • Pediatrics

Fellowship:

  • Boston Children's Hospital/Dana-Farber Cancer Institute, Pediatric Hematology/Oncology

Residency:

  • Boston Children's Hospital, Pediatrics

Medical School:

  • University of California, San Diego School of Medicine

Recent Awards:

  • Dyson Scholar Award, DFCI 1998
  • Benacerraf-Frei Investigator, DFCI 1998
  • Stephen E. Sallan Leadership award 2004

Research

Neuroblastoma and Cancer Survivorship


The focus of our research is in two major areas: the treatment of patients with solid tumors - notably neuroblastoma and Wilms' tumor - and the study of survivors of childhood cancer. In treating patients with neuroblastoma, our approach has been to intensify therapy using high-dose therapy in tandem with stem cell rescue. In addition, we are studying new approaches to the treatment of minimal residual neuroblastoma, including antiangiogenic agents, demethylating agents, and immunomodulatory approaches. (We are participants in the New Agents in Neuroblastoma Therapy consortium.) Studies of survivors of neuroblastoma are also under way. In research on medical late effects, we have been studying young adult patients with a history of cancer treatment, hoping to delineate the morbidity of a variety of therapies and to introduce screening and prevention in this group of patients. We also have completed an early mammography trial after chest irradiation, showing that women who were treated with chest radiation are at significant risk of breast cancer and that mammography detects early tumors in this cohort. A prevention trial using tamoxifen for these women is in analysis. Moreover, we are active participants in the largest childhood cancer survivor cohort study, the Childhood Cancer Survivor Study, involving 24 centers and over 17,000 survivors. We have completed an analysis of breast cancers in that cohort, and are studying risk factors for secondary sarcomas. Interventional studies using the same cohort are under way, including a web-based smoking cessation intervention, an analysis of breast cancer screening behaviors, and a planned study of renal disease screening.

Long-Term Morbidity and Mortality Among Survivors of Neuroblastoma Diagnosed During Infancy: A Report From the Childhood Cancer Survivor Study. J Clin Oncol. 2023 Mar 10; 41(8):1565-1576.
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Association of Changes in Cancer Therapy Over 3 Decades With Risk of Subsequent Breast Cancer Among Female Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study (CCSS). JAMA Oncol. 2022 Oct 13.
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Collaboration to Promote Research and Improve Clinical Care in the Evolving Field of Childhood Cancer Predisposition. Cancer Prev Res (Phila). 2022 10 04; 15(10):645-652.
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Leveraging Clinical Trial Populations and Data from the Children's Oncology Group for Cancer Survivorship Research. Cancer Epidemiol Biomarkers Prev. 2022 09 02; 31(9):1675-1682.
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Predicting chronic morbidity in childhood cancer survivors. Nat Med. 2022 08; 28(8):1539-1540.
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Circulating Tumor DNA Is Associated with Response and Survival in Patients with Advanced Leiomyosarcoma. Clin Cancer Res. 2022 06 13; 28(12):2579-2586.
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Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533. J Clin Oncol. 2022 09 10; 40(26):3047-3056.
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Advanced Retinoblastoma Presenting with Cataract in a Child with Limited Access to Primary Care. J Pediatr. 2022 08; 247:171-172.
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Population-Based Newborn Screening for Germline TP53 Variants: Clinical Benefits, Cost-Effectiveness, and Value of Further Research. J Natl Cancer Inst. 2022 05 09; 114(5):722-731.
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Breast Cancer Screening Among Childhood Cancer Survivors Treated Without Chest Radiation: Clinical Benefits and Cost-Effectiveness. J Natl Cancer Inst. 2022 02 07; 114(2):235-244.
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Estimated Cost-effectiveness of Genetic Testing in Siblings of Newborns With Cancer Susceptibility Gene Variants. JAMA Netw Open. 2021 10 01; 4(10):e2129742.
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Socioeconomic disparities in survival after high-risk neuroblastoma treatment with modern therapy. Pediatr Blood Cancer. 2021 10; 68(10):e29127.
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Universal newborn genetic screening for pediatric cancer predisposition syndromes: model-based insights. Genet Med. 2021 07; 23(7):1366-1371.
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Impact of Risk-Adapted Therapy for Pediatric Hodgkin Lymphoma on Risk of Long-Term Morbidity: A Report From the Childhood Cancer Survivor Study. J Clin Oncol. 2021 07 10; 39(20):2266-2275.
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Timely pediatric cancer diagnoses: An unexpected casualty of the COVID-19 surge. Pediatr Blood Cancer. 2020 12; 67(12):e28729.
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Cost-Effectiveness of the International Late Effects of Childhood Cancer Guideline Harmonization Group Screening Guidelines to Prevent Heart Failure in Survivors of Childhood Cancer. J Clin Oncol. 2020 11 20; 38(33):3851-3862.
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Clinical Benefits, Harms, and Cost-Effectiveness of Breast Cancer Screening for Survivors of Childhood Cancer Treated With Chest Radiation : A Comparative Modeling Study. Ann Intern Med. 2020 09 01; 173(5):331-341.
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Prospective Evaluation of Radiation Dose Escalation in Patients With High-Risk Neuroblastoma and Gross Residual Disease After Surgery: A Report From the Children's Oncology Group ANBL0532 Study. J Clin Oncol. 2020 08 20; 38(24):2741-2752.
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Incidence of and risk factors for late cholecystectomy in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Eur J Cancer. 2020 07; 133:4-13.
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Racial and Ethnic Differences in Communication and Care for Children With Advanced Cancer. J Pain Symptom Manage. 2020 10; 60(4):782-789.
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Linking population-based registries to identify familial cancer risk in childhood cancer. Cancer. 2020 07 01; 126(13):3076-3083.
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Life Expectancy of Adult Survivors of Childhood Cancer Over 3 Decades. JAMA Oncol. 2020 03 01; 6(3):350-357.
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Unrealistic parental expectations for cure in poor-prognosis childhood cancer. Cancer. 2020 01 15; 126(2):416-424.
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Autonomous early detection of eye disease in childhood photographs. Sci Adv. 2019 10; 5(10):eaax6363.
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Effect of Tandem Autologous Stem Cell Transplant vs Single Transplant on Event-Free Survival in Patients With High-Risk Neuroblastoma: A Randomized Clinical Trial. JAMA. 2019 08 27; 322(8):746-755.
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Solid organ transplantation after treatment for childhood cancer: a retrospective cohort analysis from the Childhood Cancer Survivor Study. Lancet Oncol. 2019 10; 20(10):1420-1431.
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Late-onset anorectal disease and psychosocial impact in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer. 2019 11 01; 125(21):3873-3881.
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Promoting Breast Cancer Surveillance: The EMPOWER Study, a Randomized Clinical Trial in the Childhood Cancer Survivor Study. J Clin Oncol. 2019 08 20; 37(24):2131-2140.
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Mortality After Breast Cancer Among Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. J Clin Oncol. 2019 08 20; 37(24):2120-2130.
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Cancer Treatment-Related Infertility: A Critical Review of the Evidence. JNCI Cancer Spectr. 2019 Mar; 3(1):pkz008.
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Role of the extent of prophylactic regional lymph node radiotherapy on survival in high-risk neuroblastoma: A report from the COG A3973 study. Pediatr Blood Cancer. 2019 07; 66(7):e27736.
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Risk of solid subsequent malignant neoplasms after childhood Hodgkin lymphoma-Identification of high-risk populations to guide surveillance: A report from the Late Effects Study Group. Cancer. 2019 04 15; 125(8):1373-1383.
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Long-Term Risk of Venous Thromboembolism in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. J Clin Oncol. 2018 Sep 14; JCO2018784595.
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Perceptions of future health and cancer risk in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Cancer. 2018 08; 124(16):3436-3444.
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Long-term psychological and educational outcomes for survivors of neuroblastoma: A report from the Childhood Cancer Survivor Study. Cancer. 2018 08 01; 124(15):3220-3230.
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Late Infection-Related Mortality in Asplenic Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. J Clin Oncol. 2018 06 01; 36(16):1571-1578.
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Longitudinal assessment of late-onset neurologic conditions in survivors of childhood central nervous system tumors: a Childhood Cancer Survivor Study report. Neuro Oncol. 2018 01 10; 20(1):132-142.
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Screening with whole-body magnetic resonance imaging in pediatric subjects with Li-Fraumeni syndrome: A single institution pilot study. Pediatr Blood Cancer. 2018 Feb; 65(2).
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Retinoblastoma and Neuroblastoma Predisposition and Surveillance. Clin Cancer Res. 2017 07 01; 23(13):e98-e106.
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Cancer Surveillance in Gorlin Syndrome and Rhabdoid Tumor Predisposition Syndrome. Clin Cancer Res. 2017 Jun 15; 23(12):e62-e67.
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PTEN, DICER1, FH, and Their Associated Tumor Susceptibility Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood. Clin Cancer Res. 2017 Jun 15; 23(12):e76-e82.
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Understanding predictors of continued long-term pediatric cancer care across the region: A report from the Consortium for New England Childhood Cancer Survivors. Pediatr Blood Cancer. 2017 Oct; 64(10).
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Survival and Late Effects after Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancy at Less than Three Years of Age. Biol Blood Marrow Transplant. 2017 Aug; 23(8):1327-1334.
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Neuroblastoma. Nat Rev Dis Primers. 2016 11 10; 2:16078.
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Patterns of Relapse in High-Risk Neuroblastoma Patients Treated With and Without Total Body Irradiation. Int J Radiat Oncol Biol Phys. 2017 02 01; 97(2):270-277.
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Transition and transfer of childhood cancer survivors to adult care: A national survey of pediatric oncologists. Pediatr Blood Cancer. 2017 02; 64(2):346-352.
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Multicenter Feasibility Study of Tumor Molecular Profiling to Inform Therapeutic Decisions in Advanced Pediatric Solid Tumors: The Individualized Cancer Therapy (iCat) Study. JAMA Oncol. 2016 May 01; 2(5):608-615.
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Chronic Conditions and Utility-Based Health-Related Quality of Life in Adult Childhood Cancer Survivors. J Natl Cancer Inst. 2016 09; 108(9).
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Breast Cancer Risk in Childhood Cancer Survivors Without a History of Chest Radiotherapy: A Report From the Childhood Cancer Survivor Study. J Clin Oncol. 2016 Mar 20; 34(9):910-8.
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Health care utilization, lifestyle, and emotional factors and mammography practices in the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev. 2015 Nov; 24(11):1699-706.
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Intestinal Obstruction in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. J Clin Oncol. 2015 Sep 10; 33(26):2893-900.
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An Increased Risk of Second Malignant Neoplasms After Rhabdomyosarcoma: Population-Based Evidence for a Cancer Predisposition Syndrome? Pediatr Blood Cancer. 2016 Feb; 63(2):196-201.
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A phase I trial combining decitabine/dendritic cell vaccine targeting MAGE-A1, MAGE-A3 and NY-ESO-1 for children with relapsed or therapy-refractory neuroblastoma and sarcoma. Cancer Immunol Immunother. 2015 Oct; 64(10):1251-60.
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Childhood Cancer Survivor Study participants' perceptions and understanding of the Affordable Care Act. J Clin Oncol. 2015 Mar 01; 33(7):764-72.
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Clinical cancer advances 2015: Annual report on progress against cancer from the American Society of Clinical Oncology. J Clin Oncol. 2015 Mar 01; 33(7):786-809.
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Parent decision-making around the genetic testing of children for germline TP53 mutations. Cancer. 2015 Jan 15; 121(2):286-93.
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Breast cancer detection among young survivors of pediatric Hodgkin lymphoma with screening magnetic resonance imaging. Cancer. 2014 Aug 15; 120(16):2507-13.
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Routine echocardiography screening for asymptomatic left ventricular dysfunction in childhood cancer survivors: a model-based estimation of the clinical and economic effects. Ann Intern Med. 2014 May 20; 160(10):661-71.
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Infections among long-term survivors of childhood and adolescent cancer: a report from the Childhood Cancer Survivor Study. Cancer. 2014 Aug 15; 120(16):2514-21.
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Breast cancer after chest radiation therapy for childhood cancer. J Clin Oncol. 2014 Jul 20; 32(21):2217-23.
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Impaired testicular function after an ifosfamide-containing regimen for pediatric osteosarcoma: a case series and review of the literature. J Pediatr Hematol Oncol. 2014 Apr; 36(3):237-40.
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Blood pressure is associated with occult cardiovascular disease in prospectively studied Hodgkin lymphoma survivors after chest radiation. Leuk Lymphoma. 2014 Nov; 55(11):2477-83.
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Synchronous small bowel and atypical primary leiomyosarcoma of inferior vena cava in a patient with RB1 mutation. Abdom Imaging. 2014 Feb; 39(1):33-9.
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Late effects in children treated with intensive multimodal therapy for high-risk neuroblastoma: high incidence of endocrine and growth problems. Bone Marrow Transplant. 2014 Apr; 49(4):502-8.
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Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers. Cancer. 2014 Apr 01; 120(7):1068-75.
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Partnership for health-2, a web-based versus print smoking cessation intervention for childhood and young adult cancer survivors: randomized comparative effectiveness study. J Med Internet Res. 2013 Nov 05; 15(11):e218.
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Pulmonary outcomes in survivors of childhood central nervous system malignancies: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer. 2014 Feb; 61(2):319-25.
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The cyclophosphamide equivalent dose as an approach for quantifying alkylating agent exposure: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer. 2014 Jan; 61(1):53-67.
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Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial. Lancet Oncol. 2013 Sep; 14(10):999-1008.
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Infertility, infertility treatment, and achievement of pregnancy in female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study cohort. Lancet Oncol. 2013 Aug; 14(9):873-81.
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Prospective study of the efficacy of breast magnetic resonance imaging and mammographic screening in survivors of Hodgkin lymphoma. J Clin Oncol. 2013 Jun 20; 31(18):2282-8.
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A pilot study of tandem high-dose chemotherapy with stem cell rescue as consolidation for high-risk neuroblastoma: Children's Oncology Group study ANBL00P1. Bone Marrow Transplant. 2013 Jul; 48(7):947-52.
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A prospective study of expectant observation as primary therapy for neuroblastoma in young infants: a Children's Oncology Group study. Ann Surg. 2012 Oct; 256(4):573-80.
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Influence of new late effects on quality of life over time in Hodgkin lymphoma Survivors: a longitudinal survey study. Ann Oncol. 2013 Jan; 24(1):226-30.
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Pediatric Hodgkin lymphoma: trade-offs between short- and long-term mortality risks. Blood. 2012 Sep 13; 120(11):2195-202.
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Risk factors associated with secondary sarcomas in childhood cancer survivors: a report from the childhood cancer survivor study. Int J Radiat Oncol Biol Phys. 2012 Sep 01; 84(1):224-30.
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Feasibility of a tandem autologous peripheral blood stem cell transplant regimen for high risk neuroblastoma in a cooperative group setting: a Pediatric Oncology Group study: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2012 Nov; 59(5):902-7.
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New insights into the risk of breast cancer in childhood cancer survivors treated with chest radiation: A report from the Childhood Cancer Survivor Study (CCSS) and the Women's Environmental Cancer and Radiation Epidemiology (WECARE) Study. J Clin Oncol. 2012 Jun 20; 30(18_suppl):CRA9513.
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Summaries for patients. Increased risk for gastrointestinal cancer in childhood cancer survivors. Ann Intern Med. 2012 Jun 05; 156(11):I-36.
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Secondary gastrointestinal cancer in childhood cancer survivors: a cohort study. Ann Intern Med. 2012 Jun 05; 156(11):757-66, W-260.
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Childhood Cancer Survivor Study participants' perceptions and knowledge of health insurance coverage: implications for the Affordable Care Act. J Cancer Surviv. 2012 Sep; 6(3):251-9.
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Employment and insurance in survivors of Hodgkin lymphoma and their siblings: a questionnaire study. Leuk Lymphoma. 2012 Aug; 53(8):1474-80.
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Tumor histology during induction therapy in patients with high-risk neuroblastoma. Pediatr Blood Cancer. 2012 Sep; 59(3):506-10.
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How confident are young adult cancer survivors in managing their survivorship care? A report from the LIVESTRONG™ Survivorship Center of Excellence Network. J Cancer Surviv. 2011 Dec; 5(4):371-81.
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Clinical practice. Adult primary care after childhood acute lymphoblastic leukemia. N Engl J Med. 2011 Oct 13; 365(15):1417-24.
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Long-term health-related outcomes in survivors of childhood cancer treated with HSCT versus conventional therapy: a report from the Bone Marrow Transplant Survivor Study (BMTSS) and Childhood Cancer Survivor Study (CCSS). Blood. 2011 Aug 04; 118(5):1413-20.
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Quantifying alkylating agent exposure: Evaluation of the cyclophosphamide equivalent dose-A report from the Childhood Cancer Survivor Study. J Clin Oncol. 2011 May 20; 29(15_suppl):9547.
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Disseminating a smoking cessation intervention to childhood and young adult cancer survivors: baseline characteristics and study design of the partnership for health-2 study. BMC Cancer. 2011 May 11; 11:165.
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Survivors of childhood cancer have increased risk of gastrointestinal complications later in life. Gastroenterology. 2011 May; 140(5):1464-71.e1.
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Cardiovascular disease: cause of morbidity and mortality in adult survivors of childhood cancers. Circ Res. 2011 Mar 04; 108(5):619-28.
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The current status of follow-up services for childhood cancer survivors, are we meeting goals and expectations: a report from the Consortium for New England Childhood Cancer Survivors. Pediatr Blood Cancer. 2011 Dec 01; 57(6):1062-6.
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Clinical cancer advances 2010: annual report on progress against cancer from the American Society of Clinical Oncology. J Clin Oncol. 2010 Dec 20; 28(36):5327-47.
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Breastfeeding in survivors of Hodgkin lymphoma treated with chest radiotherapy. Cancer. 2010 Oct 15; 116(20):4866-71.
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Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study. Pediatr Blood Cancer. 2010 Oct; 55(4):629-38.
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Phase II randomized comparison of topotecan plus cyclophosphamide versus topotecan alone in children with recurrent or refractory neuroblastoma: a Children's Oncology Group study. J Clin Oncol. 2010 Aug 20; 28(24):3808-15.
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Decision analysis to compare treatment strategies for Stage I/favorable histology Wilms tumor. Pediatr Blood Cancer. 2010 Jul 01; 54(7):879-84.
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Pharmacotherapy of neuroblastoma. Expert Opin Pharmacother. 2010 Jun; 11(9):1467-78.
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Inconsistent mammography perceptions and practices among women at risk of breast cancer following a pediatric malignancy: a report from the Childhood Cancer Survivor Study. Cancer Causes Control. 2010 Oct; 21(10):1585-95.
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Systematic review: surveillance for breast cancer in women treated with chest radiation for childhood, adolescent, or young adult cancer. Ann Intern Med. 2010 Apr 06; 152(7):444-55; W144-54.
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A model-based estimate of cumulative excess mortality in survivors of childhood cancer. Ann Intern Med. 2010 Apr 06; 152(7):409-17, W131-8.
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Health status of the oldest adult survivors of cancer during childhood. Cancer. 2010 Jan 15; 116(2):497-505.
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Physician preferences and knowledge gaps regarding the care of childhood cancer survivors: a mailed survey of pediatric oncologists. J Clin Oncol. 2010 Feb 10; 28(5):878-83.
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Ovarian tissue autologous transplantation to the upper extremity for girls receiving abdominal/pelvic radiation: 20-year follow-up of reproductive endocrine function. J Pediatr Adolesc Gynecol. 2010 Apr; 23(2):107-10.
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General internist communication about sexual function with cancer survivors. J Gen Intern Med. 2009 Nov; 24 Suppl 2:S407-11.
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Suicide ideation in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2010 Feb 01; 28(4):655-61.
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Caring for cancer survivors: a survey of primary care physicians. Cancer. 2009 Sep 15; 115(18 Suppl):4409-18.
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Long-term outcomes in survivors of neuroblastoma: a report from the Childhood Cancer Survivor Study. J Natl Cancer Inst. 2009 Aug 19; 101(16):1131-40.
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Radiation dose and breast cancer risk in the childhood cancer survivor study. J Clin Oncol. 2009 Aug 20; 27(24):3901-7.
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Preferences and knowledge gaps among pediatric oncologists regarding the care of childhood cancer survivors: A survey of nearly 1,200 physicians. J Clin Oncol. 2009 May 20; 27(15_suppl):6561.
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Cancer care and cancer survivorship care in the United States: will we be able to care for these patients in the future? J Oncol Pract. 2009 May; 5(3):119-23.
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Chronic disease in the Childhood Cancer Survivor Study cohort: a review of published findings. J Clin Oncol. 2009 May 10; 27(14):2339-55.
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Breast cancer surveillance practices among women previously treated with chest radiation for a childhood cancer. JAMA. 2009 Jan 28; 301(4):404-14.
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The LIVESTRONG Survivorship Center of Excellence Network. J Cancer Surviv. 2009 Mar; 3(1):4-11.
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Clinical cancer advances 2008: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology. J Clin Oncol. 2009 Feb 10; 27(5):812-26.
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Long-term smoking cessation outcomes among childhood cancer survivors in the Partnership for Health Study. J Clin Oncol. 2009 Jan 01; 27(1):52-60.
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Lung metastases in neuroblastoma at initial diagnosis: A report from the International Neuroblastoma Risk Group (INRG) project. Pediatr Blood Cancer. 2008 Nov; 51(5):589-92.
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Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature. 2008 Oct 16; 455(7215):975-8.
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New primary sarcomas in survivors of childhood cancer: A detailed analysis of the effects of treatment: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2008 May 20; 26(15_suppl):10007.
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F18-fluorodeoxyglucose-positron emission tomography/computed tomography screening in Li-Fraumeni syndrome. JAMA. 2008 Mar 19; 299(11):1315-9.
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Treatment of recurrent clear cell sarcoma of the kidney with brain metastasis. Pediatr Blood Cancer. 2008 Feb; 50(2):246-9.
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Health practice in long-term survivors of Hodgkin's lymphoma. Int J Radiat Oncol Biol Phys. 2008 Jun 01; 71(2):468-76.
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Laparoscopic oophoropexy prior to radiation for pediatric brain tumor and subsequent ovarian function. Hum Reprod. 2008 Jan; 23(1):117-21.
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Screening adult survivors of childhood cancer with the distress thermometer: a comparison with the SCL-90-R. Psychooncology. 2007 Nov; 16(11):1046-9.
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The effects of response bias on self-reported quality of life among childhood cancer survivors. Qual Life Res. 2007 Sep; 16(7):1211-20.
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Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays. PLoS One. 2007 Feb 28; 2(2):e255.
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Secondary sarcomas in childhood cancer survivors: a report from the Childhood Cancer Survivor Study. J Natl Cancer Inst. 2007 Feb 21; 99(4):300-8.
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Perceptions of breast cancer risk and cancer screening: a qualitative study of young, female Hodgkin's disease survivors. J Cancer Educ. 2007; 22(1):42-6.
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Transitioning to survivorship: a pilot study. J Pediatr Oncol Nurs. 2006 Nov-Dec; 23(6):335-43.
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Does MYCN amplification manifested as homogeneously staining regions at diagnosis predict a worse outcome in children with neuroblastoma? A Children's Oncology Group study. Clin Cancer Res. 2006 Oct 01; 12(19):5693-7.
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A novel pattern of transaminase elevation associated with autologous transplant for neuroblastoma. Pediatr Transplant. 2006 Sep; 10(6):669-76.
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Suicidal ideation and attempts in adult survivors of childhood cancer. J Clin Oncol. 2006 Aug 20; 24(24):3852-7.
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High-risk neuroblastoma treated with tandem autologous peripheral-blood stem cell-supported transplantation: long-term survival update. J Clin Oncol. 2006 Jun 20; 24(18):2891-6.
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A comparison between long-term survivors of Hodgkin's disease and their siblings on fatigue level and factors predicting for increased fatigue. Ann Oncol. 2005 Dec; 16(12):1949-55.
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Hyperdiploidy plus nonamplified MYCN confers a favorable prognosis in children 12 to 18 months old with disseminated neuroblastoma: a Pediatric Oncology Group study. J Clin Oncol. 2005 Sep 20; 23(27):6466-73.
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Perioperative management of a child with severe hypertension from a catecholamine secreting neuroblastoma. Paediatr Anaesth. 2005 Jul; 15(7):606-10.
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A phase I study of decitabine (DCT) in combination with doxorubicin (DOX) and cyclophosphamide (CTX) in the treatment of relapsed or refractory solid tumors: A Children's Oncology Group Study. J Clin Oncol. 2005 Jun; 23(16_suppl):8530.
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Second cancers screening in pediatric cancer survivors: A single institution study. J Clin Oncol. 2005 Jun; 23(16_suppl):8538.
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Sarcomas as a subsequent malignancy in survivors of pediatric malignancy:The Childhood Cancer Survivor Study. J Clin Oncol. 2005 Jun; 23(16_suppl):8515.
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Aggressive surgical therapy and radiotherapy for patients with high-risk neuroblastoma treated with rapid sequence tandem transplant. J Pediatr Surg. 2005 Jun; 40(6):936-41; discussion 941.
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CT-guided radiofrequency ablation of pediatric Wilms tumor in a solitary kidney. Pediatr Radiol. 2005 Sep; 35(9):923-8.
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Neuropsychological resiliency after treatment for advanced stage neuroblastoma. Bone Marrow Transplant. 2005 Jun; 35(11):1117-22.
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Sodium reduction for hypertension prevention in overweight adults: further results from the Trials of Hypertension Prevention Phase II. J Hum Hypertens. 2005 Jan; 19(1):33-45.
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Breast cancer after childhood cancer: a report from the Childhood Cancer Survivor Study. Ann Intern Med. 2004 Oct 19; 141(8):590-7.
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Cardiovascular status in long-term survivors of Hodgkin’s disease treated with chest radiotherapy. Journal of Clinical Oncology. 2004; 22(15):3139-3148.

Cardiovascular status in long-term survivors of Hodgkin's disease treated with chest radiotherapy. J Clin Oncol. 2004 Aug 01; 22(15):3139-48.
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Recurrent neuroblastoma: Randomized treatment with topotecan + cyclophosphamide (T+C) vs. topotecan alone(T). A POG/CCG Intergroup Study. J Clin Oncol. 2004 Jul 15; 22(14_suppl):8512.
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A feasibility study of tamoxifen chemoprevention in Hodgkin's disease (HD) survivors. J Clin Oncol. 2004 Jul 15; 22(14_suppl):8551.
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Association between congenital cardiovascular malformations and neuroblastoma. J Pediatr. 2004 Apr; 144(4):444-8.
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Restoration of promyelocytic leukemia protein-nuclear bodies in neuroblastoma cells enhances retinoic acid responsiveness. Cancer Res. 2004 Feb 01; 64(3):928-33.
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A feasibility study of tamoxifen chemotherapy prevention in Hodgkin’s disease (HD) survivors. Long-Term Complications of Treatment of Children and Adolescents for Cancer. 2004; (Ontario).

Transitioning to survivorship: a pilot study. Long-Term Complications of Treatment of Children and Adolescents for Cancer. 2004; (Ontario).

TP53, BRCA1, and BRCA2 tumor suppressor genes are not commonly mutated in survivors of Hodgkin's disease with second primary neoplasms. J Clin Oncol. 2003 Dec 15; 21(24):4505-9.
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The TP53, BRCA1 and BRCA2 tumor suppressor genes are not commonly mutated in survivors of Hodgkin’s disease with second primary neoplasms. Journal of Clinical Oncology. 2003; 21(24):4505-9.

Primary tumor control in patients with stage 3/4 unfavorable neuroblastoma treated with tandem double autologous stem cell transplants. J Pediatr Hematol Oncol. 2003 Dec; 25(12):934-40.
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High risk of subsequent neoplasms continues with extended follow-up of childhood Hodgkin's disease: report from the Late Effects Study Group. J Clin Oncol. 2003 Dec 01; 21(23):4386-94.
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A methodological issue in the analysis of second-primary cancer incidence in long-term survivors of childhood cancers. Am J Epidemiol. 2003 Dec 01; 158(11):1108-13.
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Utility of routine psychological screening in the childhood cancer survivor clinic. Journal of Clinical Oncology. 2003; 21(5):787-92.

Utility of routine psychological screening in the childhood cancer survivor clinic. J Clin Oncol. 2003 Mar 01; 21(5):787-92.
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Satellite DNA hypomethylation in karyotyped Wilms tumors. Cancer Genetics and Cytogenetics. 2003; 141(2):97-105.

Angiogenesis inhibitor TNP-470 during bone marrow transplant and in minimal residual disease. Transplantation in Hematology and Oncology II, Berdel WE, et al, eds. 2003; 283-298.

Successful purging of stem cell products using CD34 selection. Transplantation in Hematology and Oncology II, Berdel WE, et al, eds. 2003; 116-129.

High risk of subsequent neoplasms continues with extended follow-up of childhood Hodgkin disease: report from the Late Effects Study Group (LESG). Journal of Clinical Oncology. 2003; 21(23):4386-94.

Rapid Sequence Tandem Transplant in Children with High-Risk Neruroblastoma. Transplantation in Hematology and Oncology II, Berdel WE, et al, eds. 2003; 270-279.

Primary tumor control in patients with stage 3 and 4 unfavorable neuroblastoma treated with tandem double autologous stem cell transplants. Journal of Pediatric Hematology/Oncology. 2003; 25(12):934-40.

Breast cancer screening in women previously treated for Hodgkin's disease: a prospective cohort study. J Clin Oncol. 2002 Apr 15; 20(8):2085-91.
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Predictors of smoking initiation and cessation among childhood cancer survivors: a report from the childhood cancer survivor study. J Clin Oncol. 2002 Mar 15; 20(6):1608-16.
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Rapid sequence tandem transplant for advanced neuroblastoma: update and patterns of relapse. Advances in Neuroblastoma Research. 2002; (Paris).

Predictors of Smoking Initiation and Cessation Among Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study. Journal of Clinical Oncology. 2002; 20(6):1608-1616.

MYCN copy number and hyperdiploidy: do they define a favourable prognostic group in neuroblastoma patients between 12 and 24 months of age? A COG study. Advances in Neuroblastoma Research. 2002; (Paris ).

Neuropsychological and psychosocial resiliency in children treated for neuroblastoma. Advances in Neuroblastoma Research. 2002; (Paris).

Breast cancer screening in women previously treated for Hodgkin’s disease: A prospective cohort study. Journal of Clinical Oncology. 2002; 20(8):2085-2091.

RB1 genetic testing as a clinical service: a follow-up study. Med Pediatr Oncol. 2001 Oct; 37(4):372-8.
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Tissue-specific expression of SV40 in tumors associated with the Li-Fraumeni syndrome. Oncogene. 2001 Jul 27; 20(33):4441-9.
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Angiogenesis inhibitor TNP-470 during bone marrow transplant: safety in a preclinical model. Clin Cancer Res. 2001 Apr; 7(4):1026-32.
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High risk of infertility and long term gonadal damage in males treated with high dose cyclophosphamide for sarcoma during childhood. Cancer. 2001 Feb 01; 91(3):613-21.
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Angiogenesis inhibitor TNP-470 during bone marrow transplant: Safety in a preclinical model. Clinical Cancer Research. 2001; 7:1026-32.

Rapid-sequence tandem transplant for children with high-risk neuroblastoma. Med Pediatr Oncol. 2000 Dec; 35(6):696-700.
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CD34 selection as a stem cell purging strategy for neuroblastoma: preclinical and clinical studies. Med Pediatr Oncol. 2000 Dec; 35(6):677-82.
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Tandem high-dose therapy in rapid sequence for children with high-risk neuroblastoma. J Clin Oncol. 2000 Jul; 18(13):2567-75.
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Characteristics and outcome of children with Beckwith-Wiedemann syndrome and Wilms' tumor: a report from the National Wilms Tumor Study Group. J Clin Oncol. 2000 May; 18(10):2026-31.
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ADHD, divorce, and parental disagreement about the diagnosis and treatment. J Dev Behav Pediatr. 2000 Feb; 21(1):53-5.
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Measurement of problem-solving deficits in adults with acquired brain damage. J Head Trauma Rehabil. 2000 Feb; 15(1):724-33.
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Center surround receptive field structure of cone bipolar cells in primate retina. Vision Res. 2000; 40(14):1801-11.
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Tandem high-dose therapy in rapid sequence for children with high-risk neuroblastoma. Journal of Clinical Oncology. 2000; 18(13):2567-75.

Characteristics and outcome of children with Beckwith-Weidemann syndrome and Wilms tumor: a report from the National Wilms Tumor Study Group. Journal of Clinical Oncology. 2000; 18:2026-31.

Heterozygous germline ATM mutations do not contribute to radiation-associated malignancies after Hodgkin's disease. J Clin Oncol. 1999 Apr; 17(4):1259.
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Heterozygous germline ATM mutations do not contribute to radiation-associated malignancies after Hodgkin’s disease. Journal of Clinical Oncology. 1999; 4:1259-66.

Constitutional WT1 mutations in Wilms' tumor patients. J Clin Oncol. 1998 Nov; 16(11):3634-40.
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Severe ototoxicity following carboplatin-containing conditioning regimen for autologous marrow transplantation for neuroblastoma. Bone Marrow Transplant. 1998 Oct; 22(7):669-74.
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Childhood cancer predisposition: applications of molecular testing and future implications. J Pediatr. 1998 Mar; 132(3 Pt 1):389-97.
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Cystic neuroblastoma: emphasis on gene expression, morphology, and pathogenesis. Pediatric and Developmental Pathology. 1998; 1:17-28.

Constitutional WT1 mutations in Wilms tumor patients. Journal of Clinical Oncology. 1998; 11:3634-40.

Cystic neuroblastoma: emphasis on gene expression, morphology, and pathogenesis. Pediatr Dev Pathol. 1998 Jan-Feb; 1(1):17-28.
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The case of the missing methylphenidate. Pediatrics. 1997 Oct; 100(4):730-1.
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Inducing amenorrhea during bone marrow transplantation. A pilot study of leuprolide acetate. J Reprod Med. 1997 Sep; 42(9):537-41.
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Epidemiology of cancer in childhood.Eds. Nathan DG, Orkin SH. In: Nathan and Oski’s Hematology of Infancy and Childhood. 1997; 1071-91.

Use of growth hormone for non-growth hormone deficient children. JAMA. 1996 Dec 18; 276(23):1877-8; author reply 1878.
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Germline WT1 mutations in Wilms' tumor patients: preliminary results. Med Pediatr Oncol. 1996 Nov; 27(5):404-7.
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Percutaneous biopsy for prognostic testing of neuroblastoma. Radiology. 1996 Jul; 200(1):213-6.
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Pneumococcal conjugate vaccine primes for antibody responses to polysaccharide pneumococcal vaccine after treatment of Hodgkin’s disease. Journal of Infectious Diseases. 1996; 173(1):256-8.

Pediatric large volume peripheral blood progenitor cell collections from patients under 25 kg: a primer. J Clin Apher. 1996; 11(4):195-203.
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Pneumococcal conjugate vaccine primes for antibody responses to polysaccharide pneumococcal vaccine after treatment of Hodgkin's disease. J Infect Dis. 1996 Jan; 173(1):256-8.
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Antibody responses to polysaccharide and polysaccharide-conjugate vaccines after treatment of Hodgkin disease. Ann Intern Med. 1995 Dec 01; 123(11):828-34.
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Germline p53 mutations are frequently detected in young children with rhabdomyosarcoma. J Clin Invest. 1995 Apr; 95(4):1606-11.
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A new technique for laparoscopic prophylactic oophoropexy prior to cranial irradiation in children with medulloblastoma. Adolescent and Pediatric Gynecology. 1995; 8:77-81.

Preferential amplification of the paternal allele in neuroblastomas with n-myc amplification. In: Advances in Neuroblastoma Research. 1994; 39-43.

Overview of Familial Cancers. Genetic Resource. 1994; 8:12-19.

Preferential amplification of the paternal allele in neuroblastomas with N-myc amplification. Prog Clin Biol Res. 1994; 385:43-9.
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Screening children at genetic risk of cancer. Curr Opin Pediatr. 1993 Dec; 5(6):712-5.
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Prenatal detection of neuroblastoma: a ten-year experience from the Dana-Farber Cancer Institute and Children's Hospital. Pediatrics. 1993 Sep; 92(3):358-64.
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Preferential amplification of the paternal allele of the N-myc gene in human neuroblastomas. Nat Genet. 1993 Jun; 4(2):191-4.
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Cognitive remediation in traumatic brain injury: update and issues. Arch Phys Med Rehabil. 1993 Feb; 74(2):204-13.
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Stress, appraisal, and coping in mothers of disabled and nondisabled children. J Pediatr Psychol. 1992 Oct; 17(5):587-605.
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Structure and expression of the Xenopus retinoblastoma gene. Dev Biol. 1992 Sep; 153(1):141-9.
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Rhabdomyosarcoma and other soft tissue sarcomas of childhood. Curr Opin Oncol. 1992 Aug; 4(4):689-95.
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Identification of cancer-prone individuals: p53 and family cancer syndromes. J Natl Cancer Inst Monogr. 1992; (12):123-4.
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Cancer Survivor Initiative Project (National Cancer Institute Contract MAO NCICC)-84332 (PI:Patenaude). Curriculum for health care providers working with young adult survivors. Co-author of medical information summaries section of curriculum. 1992.

Neuroblastoma. The Fetus. 1991; 1:1-4.

p53 functions as a cell cycle control protein in osteosarcomas. Mol Cell Biol. 1990 Nov; 10(11):5772-81.
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Parameters of emotional processing in neuropsychiatric disorders: conceptual issues and a battery of tests. J Commun Disord. 1990 Aug-Oct; 23(4-5):247-71.
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First year after stroke: tracking cognitive and affective deficits. Arch Phys Med Rehabil. 1989 Apr; 70(4):297-302.
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Unilateral spatial neglect: biases in contralateral search and fine spatial attention. Arch Clin Neuropsychol. 1988; 3(3):213-25.
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Proper and common nouns: form class judgments in Broca's aphasia. Brain Lang. 1986 May; 28(1):114-25.
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Psychosocial aspects of living with cancer: a review of the literature. Int J Psychiatry Med. 1981-1982; 11(4):303-29.
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Assessment and treatment of psychosocial problems of the cancer patient: a case study. Cancer Nurs. 1980 Apr; 3(2):111-9.
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Male contraception and family planning: a social and historical review. Fertil Steril. 1977 Dec; 28(12):1271-9.
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The effect of hyperbaric oxygen on communication function in adults with aphasia secondary to stroke. J Speech Hear Res. 1972 Mar; 15(1):42-8.
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The effect of hyperbaric oxygen on the mental and verbal ability of stroke patients. Stroke. 1972 Jan-Feb; 3(1):10-5.
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Music as a facilitator for visual motor sequencing tasks in children with cerebral palsy. Dev Med Child Neurol. 1971 Jun; 13(3):335-42.
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Perceptual and intellectual problems in hemiplegia: implications for rehabilitation. Med Clin North Am. 1969 May; 53(3):575-83.
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The relationship between impersistence, intellectual function and outcome of rehabilitation in patients with left hemiplegia. Neurology. 1968 Sep; 18(9):852-61.
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Follow-up study of the results of anterior choroidal artery occlusion and subtemporal chemopallidectomy in parkinson's disease: an independent appraisal. J Am Geriatr Soc. 1956 Dec; 4(12):1249-57.
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