Paul J. Catalano, ScD

Paul J. Catalano, ScD


Contact Information

Office Phone Number

(617) 632-2441


(617) 632-2444


Paul J. Catalano, ScD

Dr. Catalano received his ScD in biostatistics from Harvard School of Public Health in 1991. He then completed a two-year postdoctoral fellowship there and at DFCI, joined the faculty in 1993, and became Associate Chair of the department in 2001 and Senior Lecturer in 2005. In 2007 he became Director of the Biostatistics Core Facility of the DF/HCC. His collaborative work is primarily in radiation oncology, radiology, outcomes research and cancer biology with investigators at the DF/HCC, cancer clinical trials and translational studies in gastrointestinal malignancies with the Eastern Cooperative Oncology Group and quality-of-care research in lung and colorectal cancer with the CanCORS Consortium. His methodological research is in the areas of multiple outcomes modeling and methods for hierarchical clustered data.



Senior Lecturer in Biostatistics, Harvard T.H. Chan School of Public Health

Recent Awards

  • Harvard University Roger L. Nichols Excellence in Teaching Award 2009
  • Harvard University Outstanding Teaching Assistant Award 1990
  • Harvard University Robert Reed Prize in Biostatistical Science 1990
  • National Research Service Award – Traineeship 1987-1988


    Biostatistical Methods for Multiple Outcomes and Clustered Data

    The main line of my methodologic statistical research is the design and analysis of studies involving mixtures of discrete and continuous outcomes, with a focus on dose-response modeling and quantitative risk assessment. Toxicologic and other early evaluation studies in animals are a specific application area, but problems related to multiple outcomes arise in a variety of research contexts.

    One important application of such methods is the determination of overall risk from an exposure to an agent (pharmaceutical, environmental contaminant, etc.) when the outcomes are naturally multivariate. Although assessing probabilistic risk is usually straightforward with a single outcome, in the multivariate setting the situation is often more complex because outcomes may be observed simultaneously or in a hierarchical fashion. The statistical analysis must carefully account for these features of the response profile.

    My collaborative research in cancer involves statistical support for the design, monitoring, and analysis of clinical trials in gastrointestinal malignancies, design and analysis of prospective and retrospective studies in radiation oncology, radiology, outcomes research and cancer biology, collaboration on studies with quality-of-life and translational-science endpoints, and analysis of all phases of clinical trials and quality of care studies in lung cancer and colorectal cancer.

    Research Departments


      • A genomic score to predict local control among patients with brain metastases managed with radiation. Neuro Oncol. 2023 Oct 03; 25(10):1815-1827. View in: Pubmed

      • Paclitaxel With or Without Cixutumumab as Second-Line Treatment of Metastatic Esophageal or Gastroesophageal Junction Cancer: A Randomized Phase II ECOG-ACRIN Trial. Oncologist. 2023 09 07; 28(9):827-e822. View in: Pubmed

      • Bevacizumab in Combination With Oxaliplatin, Fluorouracil, and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results From the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol. 2023 Jul 20; 41(21):3670-3675. View in: Pubmed

      • Multi-institutional Characterization of Outcomes for Pediatric and Young Adult Patients With High-Risk Myxopapillary Ependymoma After Radiation Therapy. Int J Radiat Oncol Biol Phys. 2023 Jul 10. View in: Pubmed

      • In situ psycho-cognitive assessments support self-determined urban green exercise time. Urban For Urban Green. 2023 Aug; 86. View in: Pubmed

      • Phase I study of a novel glioblastoma radiation therapy schedule exploiting cell-state plasticity. Neuro Oncol. 2023 06 02; 25(6):1100-1112. View in: Pubmed

      • Incidence proportion and prognosis of leptomeningeal disease among patients with breast vs. non-breast primaries. Neuro Oncol. 2023 05 04; 25(5):973-983. View in: Pubmed

      • The GIANT trial (ECOG-ACRIN EA2186) methods paper: A randomized phase II study of gemcitabine and nab-paclitaxel compared with 5-fluorouracil, leucovorin, and liposomal irinotecan in older patients with treatment-naïve metastatic pancreatic cancer - defining a new treatment option for older vulnerable patients. J Geriatr Oncol. 2023 04; 14(3):101474. View in: Pubmed

      • Phase II study of nivolumab and salvage nivolumab/ipilimumab in treatment-naïve patients with advanced non-clear cell renal cell carcinoma (HCRN GU16-260-Cohort B). J Immunother Cancer. 2023 03; 11(3). View in: Pubmed

      • Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis. Sci Rep. 2022 Nov 09; 12(1):19055. View in: Pubmed

      • Phase III Prospectively Randomized Trial of Perioperative 5-FU After Curative Resection for Colon Cancer: An Intergroup Trial of the ECOG-ACRIN Cancer Research Group (E1292). Ann Surg Oncol. 2023 Feb; 30(2):1099-1109. View in: Pubmed

      • A phase II study of sapanisertib (TAK-228) a mTORC1/2 inhibitor in rapalog-resistant advanced pancreatic neuroendocrine tumors (PNET): ECOG-ACRIN EA2161. Invest New Drugs. 2022 12; 40(6):1306-1314. View in: Pubmed

      • Randomized Study of Temozolomide or Temozolomide and Capecitabine in Patients With Advanced Pancreatic Neuroendocrine Tumors (ECOG-ACRIN E2211). J Clin Oncol. 2023 03 01; 41(7):1359-1369. View in: Pubmed

      • Clinical validation of deep learning algorithms for radiotherapy targeting of non-small-cell lung cancer: an observational study. Lancet Digit Health. 2022 09; 4(9):e657-e666. View in: Pubmed

      • ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT/IGRT. Pract Radiat Oncol. 2022 Jul-Aug; 12(4):335-347. View in: Pubmed

      • Phase II Study of Nivolumab and Salvage Nivolumab/Ipilimumab in Treatment-Naive Patients With Advanced Clear Cell Renal Cell Carcinoma (HCRN GU16-260-Cohort A). J Clin Oncol. 2022 09 01; 40(25):2913-2923. View in: Pubmed

      • Predictors of long-term survival among patients with brain metastases. Neuro Oncol. 2022 03 12; 24(3):494-496. View in: Pubmed

      • Incidence and Predictors of Neurologic Death in Patients with Brain Metastases. World Neurosurg. 2022 06; 162:e401-e415. View in: Pubmed

      • Magnetic Resonance-Guided Prostate Stereotactic Body Radiation Therapy With Daily Online Plan Adaptation: Results of a Prospective Phase 1 Trial and Supplemental Cohort. Adv Radiat Oncol. 2022 Sep-Oct; 7(5):100934. View in: Pubmed

      • Frequency, etiologies, risk factors, and sequelae of falls among patients with brain metastases: A population- and institutional-level analysis. Neurooncol Pract. 2022 Apr; 9(2):114-122. View in: Pubmed

      • Radiation Dose to the Intraprostatic Urethra Correlates Strongly With Urinary Toxicity After Prostate Stereotactic Body Radiation Therapy: A Combined Analysis of 23 Prospective Clinical Trials. Int J Radiat Oncol Biol Phys. 2022 01 01; 112(1):75-82. View in: Pubmed

      • Cultural Sets Shape Adult Conceptualizations and Relationships to Nature. Sustainability. 2021 Oct 02; 13(20). View in: Pubmed

      • Lung Cancer Strategist Program: A novel care delivery model to improve timeliness of diagnosis and treatment in high-risk patients. Healthc (Amst). 2021 Sep; 9(3):100563. View in: Pubmed

      • Emergency department visits and inpatient hospitalizations among older patients with brain metastases: a dual population- and institution-level analysis. Neurooncol Pract. 2021 Oct; 8(5):569-580. View in: Pubmed

      • Population-based estimates of survival among elderly patients with brain metastases. Neuro Oncol. 2021 04 12; 23(4):661-676. View in: Pubmed

      • Intracerebral haemorrhage in patients with brain metastases receiving therapeutic anticoagulation. J Neurol Neurosurg Psychiatry. 2021 Mar 09. View in: Pubmed

      • F-18 FDG perfusion PET: intraprocedural assessment of the liver tumor ablation margin. Abdom Radiol (NY). 2021 07; 46(7):3437-3447. View in: Pubmed

      • Assessing ablation margins of FDG-avid liver tumors during PET/CT-guided thermal ablation procedures: a retrospective study. Eur J Nucl Med Mol Imaging. 2021 08; 48(9):2914-2924. View in: Pubmed

      • The Relationship between Nature Deprivation and Individual Wellbeing across Urban Gradients under COVID-19. Int J Environ Res Public Health. 2021 02 05; 18(4). View in: Pubmed

      • ACE2 abrogates tumor resistance to VEGFR inhibitors suggesting angiotensin-(1-7) as a therapy for clear cell renal cell carcinoma. Sci Transl Med. 2021 01 20; 13(577). View in: Pubmed

      • Seizures Among Patients with Brain Metastases: A Population- and Institutional-level Analysis. Neurology. 2021 Jan 05. View in: Pubmed

      • Hospice Utilization in Elderly Patients With Brain Metastases. J Natl Cancer Inst. 2020 12 14; 112(12):1251-1258. View in: Pubmed

      • Arterial Spin Labeled Perfusion MRI for the Evaluation of Response to Tyrosine Kinase Inhibition Therapy in Metastatic Renal Cell Carcinoma. Radiology. 2021 02; 298(2):332-340. View in: Pubmed

      • KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1. Cancer Immunol Res. 2021 02; 9(2):156-169. View in: Pubmed

      • Expression of T-Cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma. Clin Cancer Res. 2021 03 01; 27(5):1371-1380. View in: Pubmed

      • Association between treatment center experience and survival after diagnosis of stage I to III Merkel cell carcinoma treated with surgery with or without postoperative radiation therapy. J Am Acad Dermatol. 2021 Mar; 84(3):875-877. View in: Pubmed

      • Doxorubicin and subsequent risk of cardiovascular diseases among survivors of diffuse large B-cell lymphoma in Hong Kong. Blood Adv. 2020 10 27; 4(20):5107-5117. View in: Pubmed

      • Utility of claims data for delineation of intracranial treatment among patients with brain metastases. Neuro Oncol. 2020 10 14; 22(10):1547-1548. View in: Pubmed

      • Racial disparities in supportive medication use among older patients with brain metastases: a population-based analysis. Neuro Oncol. 2020 09 29; 22(9):1339-1347. View in: Pubmed

      • Response rate and local recurrence after concurrent immune checkpoint therapy and radiotherapy for non-small cell lung cancer and melanoma brain metastases. Cancer. 2020 12 15; 126(24):5274-5282. View in: Pubmed

      • Feasibility of hippocampal avoidance whole brain radiation in patients with hippocampal involvement: Data from a prospective study. Med Dosim. 2021 Spring; 46(1):21-28. View in: Pubmed

      • Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma. Nat Med. 2020 06; 26(6):909-918. View in: Pubmed

      • Prescription of memantine during non-stereotactic, brain-directed radiation among patients with brain metastases: a population-based study. J Neurooncol. 2020 Jul; 148(3):509-517. View in: Pubmed

      • Utility of claims data for identification of date of diagnosis of brain metastases. Neuro Oncol. 2020 04 15; 22(4):575-576. View in: Pubmed

      • The Influence of Heat on Daily Police, Medical, and Fire Dispatches in Boston, Massachusetts: Relative Risk and Time-Series Analyses. Am J Public Health. 2020 05; 110(5):662-668. View in: Pubmed

      • Master Protocol Trial Design for Efficient and Rational Evaluation of Novel Therapeutic Oncology Devices. J Natl Cancer Inst. 2020 03 01; 112(3):229-237. View in: Pubmed

      • The Role of Individual and Small-Area Social and Environmental Factors on Heat Vulnerability to Mortality Within and Outside of the Home in Boston, MA. Climate (Basel). 2020 Feb; 8(2). View in: Pubmed

      • Randomized trial of irinotecan and cetuximab (IC) versus irinotecan, cetuximab and ramucirumab (ICR) as 2nd line therapy of advanced colorectal cancer (CRC) following oxaliplatin and bevacizumb based therapy: Result of E7208. Ann Oncol. 2018 Jun; 29 Suppl 5:v110. View in: Pubmed

      • Effects of biophilic indoor environment on stress and anxiety recovery: A between-subjects experiment in virtual reality. Environ Int. 2020 03; 136:105427. View in: Pubmed

      • Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil, and Leucovorin Versus Oxaliplatin, 5-Fluorouracil, Leucovorin, and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation: A Trial of the ECOG-ACRIN Research Group (E5204). Oncologist. 2020 05; 25(5):e798-e807. View in: Pubmed

      • Effects of biophilic interventions in office on stress reaction and cognitive function: A randomized crossover study in virtual reality. Indoor Air. 2019 11; 29(6):1028-1039. View in: Pubmed

      • Incidence and Demographic Burden of HPV-Associated Oropharyngeal Head and Neck Cancers in the United States. Cancer Epidemiol Biomarkers Prev. 2019 10; 28(10):1660-1667. View in: Pubmed

      • Building Vulnerability in a Changing Climate: Indoor Temperature Exposures and Health Outcomes in Older Adults Living in Public Housing during an Extreme Heat Event in Cambridge, MA. Int J Environ Res Public Health. 2019 07 04; 16(13). View in: Pubmed

      • Phase II Study of Preoperative Chemoradiotherapy with Oxaliplatin, Infusional 5-Fluorouracil, and Cetuximab Followed by Postoperative Docetaxel and Cetuximab in Patients with Adenocarcinoma of the Esophagus: A Trial of the ECOG-ACRIN Cancer Research Group (E2205). Oncologist. 2020 01; 25(1):e53-e59. View in: Pubmed

      • A Phase 1 Study of Afatinib in Combination with Postoperative Radiation Therapy with and Without Weekly Docetaxel in Intermediate- and High-Risk Patients with Resected Squamous Cell Carcinoma of the Head and Neck. Int J Radiat Oncol Biol Phys. 2019 09 01; 105(1):132-139. View in: Pubmed

      • Effects of Postmastectomy Radiation Therapy on Immediate Tissue Expander and Acellular Dermal Matrix Reconstruction: Results of a Prospective Clinical Trial. Pract Radiat Oncol. 2019 Sep - Oct; 9(5):338-346. View in: Pubmed

      • Association of Neurosurgical Resection With Development of Pachymeningeal Seeding in Patients With Brain Metastases. JAMA Oncol. 2019 May 01; 5(5):703-709. View in: Pubmed

      • Breast cancer subtype and intracranial recurrence patterns after brain-directed radiation for brain metastases. Breast Cancer Res Treat. 2019 Jul; 176(1):171-179. View in: Pubmed

      • Study of Cathepsin B inhibition in VEGFR TKI treated human renal cell carcinoma xenografts. Oncogenesis. 2019 Feb 22; 8(3):15. View in: Pubmed

      • Local control after brain-directed radiation in patients with cystic versus solid brain metastases. J Neurooncol. 2019 Apr; 142(2):355-363. View in: Pubmed

      • irRECIST for the Evaluation of Candidate Biomarkers of Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma: Analysis of a Phase II Prospective Clinical Trial. Clin Cancer Res. 2019 04 01; 25(7):2174-2184. View in: Pubmed

      • Advanced pancreatic cancer clinical trials: The continued underrepresentation of older patients. J Geriatr Oncol. 2019 07; 10(4):540-546. View in: Pubmed

      • Nab-Paclitaxel and Gemcitabine as First-line Treatment of Advanced or Metastatic Cholangiocarcinoma: A Phase 2 Clinical Trial. JAMA Oncol. 2018 12 01; 4(12):1707-1712. View in: Pubmed

      • Neurosurgical Resection and Stereotactic Radiation Versus Stereotactic Radiation Alone in Patients with a Single or Solitary Brain Metastasis. World Neurosurg. 2019 Feb; 122:e1557-e1561. View in: Pubmed

      • Outcomes by EGFR, KRAS, and ALK Genotype After Combined Modality Therapy for Locally Advanced Non-Small-Cell Lung Cancer. JCO Precis Oncol. 2018 Nov; 2:1-18. View in: Pubmed

      • Immunotherapy and Symptomatic Radiation Necrosis in Patients With Brain Metastases Treated With Stereotactic Radiation. JAMA Oncol. 2018 08 01; 4(8):1123-1124. View in: Pubmed

      • Implications of Screening for Brain Metastases in Patients With Breast Cancer and Non-Small Cell Lung Cancer. JAMA Oncol. 2018 07 01; 4(7):1001-1003. View in: Pubmed

      • Evaluating the PD-1 Axis and Immune Effector Cell Infiltration in Oropharyngeal Squamous Cell Carcinoma. Int J Radiat Oncol Biol Phys. 2018 09 01; 102(1):137-145. View in: Pubmed

      • Funding Support and Principal Investigator Leadership of Oncology Clinical Trials Using Radiation Therapy. Int J Radiat Oncol Biol Phys. 2018 09 01; 102(1):34-43. View in: Pubmed

      • Comprehensive Genomic Profiling of Metastatic Tumors in a Phase 2 Biomarker Study of Everolimus in Advanced Renal Cell Carcinoma. Clin Genitourin Cancer. 2018 10; 16(5):341-348. View in: Pubmed

      • Cabozantinib in Patients with Advanced Merkel Cell Carcinoma. Oncologist. 2018 07; 23(7):814-821. View in: Pubmed

      • Impact of pemetrexed on intracranial disease control and radiation necrosis in patients with brain metastases from non-small cell lung cancer receiving stereotactic radiation. Radiother Oncol. 2018 03; 126(3):511-518. View in: Pubmed

      • Phase 2 study of treatment selection based on tumor thymidylate synthase expression in previously untreated patients with metastatic colorectal cancer: A trial of the ECOG-ACRIN Cancer Research Group (E4203). Cancer. 2018 02 15; 124(4):688-697. View in: Pubmed

      • Radiation toxicity in patients with collagen vascular disease and intrathoracic malignancy treated with modern radiation techniques. Radiother Oncol. 2017 11; 125(2):301-309. View in: Pubmed

      • Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study. Neuro Oncol. 2017 Oct 19; 19(11):1511-1521. View in: Pubmed

      • An Intergroup Randomized Phase II Study of Bevacizumab or Cetuximab in Combination with Gemcitabine and in Combination with Chemoradiation in Patients with Resected Pancreatic Carcinoma: A Trial of the ECOG-ACRIN Cancer Research Group (E2204). Oncology. 2018; 94(1):39-46. View in: Pubmed

      • Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy. Oral Oncol. 2017 10; 73:160-165. View in: Pubmed

      • MR- versus CT-based high-dose-rate interstitial brachytherapy for vaginal recurrence of endometrial cancer. Brachytherapy. 2017 Nov - Dec; 16(6):1159-1168. View in: Pubmed

      • Brain Metastases in Newly Diagnosed Breast Cancer: A Population-Based Study. JAMA Oncol. 2017 Aug 01; 3(8):1069-1077. View in: Pubmed

      • Estimating mono- and bi-phasic regression parameters using a mixture piecewise linear Bayesian hierarchical model. PLoS One. 2017; 12(7):e0180756. View in: Pubmed

      • An Assessment of the Quality Oncology Practice Initiative: Lessons Learned From a Detailed Assessment of a Well-Established Profession-Based Performance Measurement Program. J Healthc Qual. 2017 Jul/Aug; 39(4):e49-e58. View in: Pubmed

      • Radiation and PD-1 inhibition: Favorable outcomes after brain-directed radiation. Radiother Oncol. 2017 07; 124(1):98-103. View in: Pubmed

      • The Intensive Palliative Care Unit: Changing Outcomes for Hospitalized Cancer Patients in an Academic Medical Center. J Palliat Med. 2017 03; 20(3):285-289. View in: Pubmed

      • Outcomes with volume-based dose specification in CT-planned high-dose-rate brachytherapy for stage I-II cervical carcinoma: A 10-year institutional experience. Gynecol Oncol. 2016 Dec; 143(3):545-551. View in: Pubmed

      • Patterns of failure after reirradiation with intensity-modulated radiation therapy and the competing risk of out-of-field recurrences. Oral Oncol. 2016 10; 61:19-26. View in: Pubmed

      • Randomized Phase II Trial of Irinotecan/Docetaxel or Irinotecan/Docetaxel Plus Cetuximab for Metastatic Pancreatic Cancer: An Eastern Cooperative Oncology Group Study. Am J Clin Oncol. 2016 08; 39(4):340-5. View in: Pubmed

      • Body Mass Index and Locoregional Recurrence in Women with Early-Stage Breast Cancer. Ann Surg Oncol. 2016 11; 23(12):3870-3879. View in: Pubmed

      • Hepatic Microwave Ablation Zone Size: Correlation with Total Energy, Net Energy, and Manufacturer-Provided Chart Predictions. J Vasc Interv Radiol. 2016 Sep; 27(9):1389-1396. View in: Pubmed

      • Outcomes with image-based interstitial brachytherapy for vaginal cancer. Radiother Oncol. 2016 09; 120(3):486-492. View in: Pubmed

      • Prognostic importance of human papillomavirus (HPV) and p16 positivity in squamous cell carcinoma of the vulva treated with radiotherapy. Gynecol Oncol. 2016 08; 142(2):293-8. View in: Pubmed

      • Improving safety climate through a communication and recognition program for construction: a mixed methods study. Scand J Work Environ Health. 2016 07 01; 42(4):329-37. View in: Pubmed

      • The need for preoperative baseline arm measurement to accurately quantify breast cancer-related lymphedema. Breast Cancer Res Treat. 2016 06; 157(2):229-240. View in: Pubmed

      • Comparison of performance of various tumor response criteria in assessment of sunitinib activity in advanced gastrointestinal stromal tumors. Clin Imaging. 2016 Sep-Oct; 40(5):880-4. View in: Pubmed

      • Population-based validation of the recursive partitioning analysis-based staging system for oropharyngeal cancer. Head Neck. 2016 10; 38(10):1530-8. View in: Pubmed

      • Healthier Standards for School Meals and Snacks: Impact on School Food Revenues and Lunch Participation Rates. Am J Prev Med. 2016 10; 51(4):485-92. View in: Pubmed

      • A Psychophysical Protocol to Develop Ergonomic Recommendations for Sitting and Standing Workstations. Hum Factors. 2016 06; 58(4):574-85. View in: Pubmed

      • Variation in National Use of Long-Term ADT by Disease Aggressiveness Among Men With Unfavorable-Risk Prostate Cancer. J Natl Compr Canc Netw. 2016 04; 14(4):421-8. View in: Pubmed

      • Eastern Cooperative Oncology Group and American College of Radiology Imaging Network Randomized Phase 2 Trial of Neoadjuvant Preoperative Paclitaxel/Cisplatin/Radiation Therapy (RT) or Irinotecan/Cisplatin/RT in Esophageal Adenocarcinoma: Long-Term Outcome and Implications for Trial Design. Int J Radiat Oncol Biol Phys. 2016 Mar 15; 94(4):738-46. View in: Pubmed

      • Ipilmumab and cranial radiation in metastatic melanoma patients: a case series and review. J Immunother Cancer. 2015; 3:50. View in: Pubmed

      • The Intensive Palliative Care Unit (IPCU): Changing outcomes for hospitalized cancer patients in an academic medical center. J Clin Oncol. 2015 Oct 10; 33(29_suppl):135. View in: Pubmed

      • The risk of lymphedema after postoperative radiation therapy in endometrial cancer. J Gynecol Oncol. 2016 Jan; 27(1):e4. View in: Pubmed

      • Validation and Application of the Mass Balance Model To Determine the Effectiveness of Portable Air Purifiers in Removing Ultrafine and Submicrometer Particles in an Apartment. Environ Sci Technol. 2015 Aug 18; 49(16):9592-9. View in: Pubmed

      • Prospective assessment of deep inspiration breath-hold using 3-dimensional surface tracking for irradiation of left-sided breast cancer. Pract Radiat Oncol. 2015 Nov-Dec; 5(6):358-65. View in: Pubmed

      • Incidence, risk factors, and reasons for hospitalization among glioblastoma patients receiving chemoradiation. J Neurooncol. 2015 Aug; 124(1):137-46. View in: Pubmed

      • Rectal bleeding after radiation therapy for endometrial cancer. Radiother Oncol. 2015 May; 115(2):240-5. View in: Pubmed

      • Effects of choice architecture and chef-enhanced meals on the selection and consumption of healthier school foods: a randomized clinical trial. JAMA Pediatr. 2015 May; 169(5):431-7. View in: Pubmed

      • Changing prognostic significance of tumor stage and nodal stage in patients with squamous cell carcinoma of the oropharynx in the human papillomavirus era. Cancer. 2015 Aug 01; 121(15):2594-602. View in: Pubmed

      • Minimally invasive esophagectomy: results of a prospective phase II multicenter trial-the eastern cooperative oncology group (E2202) study. Ann Surg. 2015 Apr; 261(4):702-7. View in: Pubmed

      • Local therapies for brain metastases, competing risks, and overall survival. Int J Radiat Oncol Biol Phys. 2015 Mar 15; 91(4):718-20. View in: Pubmed

      • Paclitaxel-loaded expansile nanoparticles enhance chemotherapeutic drug delivery in mesothelioma 3-dimensional multicellular spheroids. J Thorac Cardiovasc Surg. 2015 May; 149(5):1417-24; discussion 1424-25.e1. View in: Pubmed

      • Rates and durability of response to salvage radiation therapy among patients with refractory or relapsed aggressive non-Hodgkin lymphoma. Int J Radiat Oncol Biol Phys. 2015 Jan 01; 91(1):223-31. View in: Pubmed

      • Point-of-care clinical decision support for cancer symptom management: Results of a group randomized trial. J Clin Oncol. 2014 Nov; 32(31_suppl):1. View in: Pubmed

      • Potential pitfalls of binary reporting metrics using a QOPI end-of-life (EOL) sample. J Clin Oncol. 2014 Oct 20; 32(30_suppl):261. View in: Pubmed

      • Outcomes by tumor histology and KRAS mutation status after lung stereotactic body radiation therapy for early-stage non-small-cell lung cancer. Clin Lung Cancer. 2015 Jan; 16(1):24-32. View in: Pubmed

      • Prediction of trapezius muscle activity and shoulder, head, neck, and torso postures during computer use: results of a field study. BMC Musculoskelet Disord. 2014 Sep 03; 15:292. View in: Pubmed

      • Size-resolved deposition rates for ultrafine and submicrometer particles in a residential housing unit. Environ Sci Technol. 2014 Sep 02; 48(17):10282-90. View in: Pubmed

      • Dosimetric Inhomogeneity Predicts for Long-Term Breast Pain After Breast-Conserving Therapy. Int J Radiat Oncol Biol Phys. 2015 Dec 01; 93(5):1087-95. View in: Pubmed

      • Historical controls for metastatic pancreatic cancer: benchmarks for planning and analyzing single-arm phase II trials. Clin Cancer Res. 2014 Aug 15; 20(16):4176-85. View in: Pubmed

      • Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma. Neuro Oncol. 2014 Nov; 16(11):1547-53. View in: Pubmed

      • Feasibility of using algorithm-based clinical decision support for symptom assessment and management in lung cancer. J Pain Symptom Manage. 2015 Jan; 49(1):13-26. View in: Pubmed

      • Early-stage rectal cancer: clinical and pathologic prognostic markers of time to local recurrence and overall survival after resection. Dis Colon Rectum. 2014 Apr; 57(4):449-59. View in: Pubmed

      • Impact of the new U.S. Department of Agriculture school meal standards on food selection, consumption, and waste. Am J Prev Med. 2014 Apr; 46(4):388-94. View in: Pubmed

      • Percutaneous imaging-guided cryoablation of liver tumors: predicting local progression on 24-hour MRI. AJR Am J Roentgenol. 2014 Aug; 203(2):W181-91. View in: Pubmed

      • Percutaneous treatment of hepatocellular carcinoma in patients with cirrhosis: a comparison of the safety of cryoablation and radiofrequency ablation. Eur J Radiol. 2014 Apr; 83(4):632-8. View in: Pubmed

      • Few changes in food security and dietary intake from short-term participation in the Supplemental Nutrition Assistance Program among low-income Massachusetts adults. J Nutr Educ Behav. 2014 Jan; 46(1):68-74. View in: Pubmed

      • Limitations of QOPI end-of-life (EOL) data use for purposes of accountability: Comparison of sample versus full cohort analysis. J Clin Oncol. 2013 Nov; 31(31_suppl):87. View in: Pubmed

      • Standardizing chemotherapy education for quality improvement. J Clin Oncol. 2013 Nov; 31(31_suppl):136. View in: Pubmed

      • Disease-free survival as a surrogate for overall survival in adjuvant trials of gastric cancer: a meta-analysis. J Natl Cancer Inst. 2013 Nov 06; 105(21):1600-7. View in: Pubmed

      • Progression-free survival as a surrogate for overall survival in advanced/recurrent gastric cancer trials: a meta-analysis. J Natl Cancer Inst. 2013 Nov 06; 105(21):1667-70. View in: Pubmed

      • Predicting life expectancy in patients with metastatic cancer receiving palliative radiotherapy: the TEACHH model. Cancer. 2014 Jan 01; 120(1):134-41. View in: Pubmed

      • The effect of over-commitment and reward on trapezius muscle activity and shoulder, head, neck, and torso postures during computer use in the field. Am J Ind Med. 2013 Oct; 56(10):1190-200. View in: Pubmed

      • Tablet Keyboard Configuration Affects Performance, Discomfort and Task Difficulty for Thumb Typing in a Two-Handed Grip. PLoS One. 2013; 8(6):e67525. View in: Pubmed

      • Enrollment of patients with lung and colorectal cancers onto clinical trials. J Oncol Pract. 2013 Mar; 9(2):e40-7. View in: Pubmed

      • Representativeness of participants in the cancer care outcomes research and surveillance consortium relative to the surveillance, epidemiology, and end results program. Med Care. 2013 Feb; 51(2):e9-15. View in: Pubmed

      • On determining the BMD from multiple outcomes in developmental toxicity studies when one outcome is intentionally missing. Risk Anal. 2013 Aug; 33(8):1500-9. View in: Pubmed

      • Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles. Biomaterials. 2013 Feb; 34(7):1810-9. View in: Pubmed

      • Cytoreductive surgery and intraoperative administration of paclitaxel-loaded expansile nanoparticles delay tumor recurrence in ovarian carcinoma. Ann Surg Oncol. 2013 May; 20(5):1684-93. View in: Pubmed

      • Phase II Trial of Paclitaxel/Cisplatin Followed by Surgery and Adjuvant Radiation Therapy and 5-Fluorouracil/Leucovorin for Gastric Cancer (ECOG E7296). Gastrointest Cancer Res. 2012 Nov; 5(6):191-7. View in: Pubmed

      • Association between VEGF splice isoforms and progression-free survival in metastatic colorectal cancer patients treated with bevacizumab. Clin Cancer Res. 2012 Nov 15; 18(22):6384-91. View in: Pubmed

      • Patients' expectations about effects of chemotherapy for advanced cancer. N Engl J Med. 2012 Oct 25; 367(17):1616-25. View in: Pubmed

      • Dietary intake and dietary quality of low-income adults in the Supplemental Nutrition Assistance Program. Am J Clin Nutr. 2012 Nov; 96(5):977-88. View in: Pubmed

      • Chemotherapy use and patient treatment preferences in advanced colorectal cancer: a prospective cohort study. Cancer. 2013 Feb 15; 119(4):854-62. View in: Pubmed

      • Microinvasive breast cancer: ER, PR, and HER-2/neu status and clinical outcomes after breast-conserving therapy or mastectomy. Ann Surg Oncol. 2013 Mar; 20(3):811-8. View in: Pubmed

      • Combined modality treatment for PET-positive non-Hodgkin lymphoma: favorable outcomes of combined modality treatment for patients with non-Hodgkin lymphoma and positive interim or postchemotherapy FDG-PET. Int J Radiat Oncol Biol Phys. 2012 Aug 01; 83(5):e647-54. View in: Pubmed

      • Barriers to the implementation of surveillance for stage I testicular seminoma. Int J Radiat Oncol Biol Phys. 2012 Oct 01; 84(2):383-9. View in: Pubmed

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      • Randomized phase II study of gemcitabine plus radiotherapy versus gemcitabine, 5-fluorouracil, and cisplatin followed by radiotherapy and 5-fluorouracil for patients with locally advanced, potentially resectable pancreatic adenocarcinoma. J Surg Oncol. 2010 Jun 01; 101(7):587-92. View in: Pubmed

      • Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203. J Clin Oncol. 2010 Jun 20; 28(18):2947-51. View in: Pubmed

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      • Polymorphisms in nucleotide excision repair genes, arsenic exposure, and non-melanoma skin cancer in New Hampshire. Environ Health Perspect. 2007 Aug; 115(8):1231-6. View in: Pubmed

      • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol. 2007 Apr 20; 25(12):1539-44. View in: Pubmed

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      • A phase II study of high-dose bevacizumab in combination with irinotecan, 5-fluorouracil, leucovorin, as initial therapy for advanced colorectal cancer: results from the Eastern Cooperative Oncology Group study E2200. Ann Oncol. 2006 Sep; 17(9):1399-403. View in: Pubmed

      • Association of ventricular arrhythmias detected by implantable cardioverter defibrillator and ambient air pollutants in the St Louis, Missouri metropolitan area. Occup Environ Med. 2006 Sep; 63(9):591-6. View in: Pubmed

      • XPA, haplotypes, and risk of basal and squamous cell carcinoma. Carcinogenesis. 2006 Aug; 27(8):1670-5. View in: Pubmed

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      • Increased risk of paroxysmal atrial fibrillation episodes associated with acute increases in ambient air pollution. Environ Health Perspect. 2006 Jan; 114(1):120-3. View in: Pubmed

      • Phase III study of fluorouracil, leucovorin, and levamisole in high-risk stage II and III colon cancer: final report of Intergroup 0089. J Clin Oncol. 2005 Dec 01; 23(34):8671-8. View in: Pubmed

      • Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol. 2005 Dec 01; 23(34):8706-12. View in: Pubmed

      • Disease-free survival versus overall survival as a primary end point for adjuvant colon cancer studies: individual patient data from 20,898 patients on 18 randomized trials. J Clin Oncol. 2005 Dec 01; 23(34):8664-70. View in: Pubmed

      • Quantitative risk assessment for multivariate continuous outcomes with application to neurotoxicology: the bivariate case. Biometrics. 2005 Sep; 61(3):757-66. View in: Pubmed

      • A randomized phase III study of radiotherapy alone or with 5-fluorouracil and mitomycin-C in patients with locally advanced adenocarcinoma of the pancreas: Eastern Cooperative Oncology Group study E8282. Int J Radiat Oncol Biol Phys. 2005 Aug 01; 62(5):1345-50. View in: Pubmed

      • Phase II/III study of doxorubicin with fluorouracil compared with streptozocin with fluorouracil or dacarbazine in the treatment of advanced carcinoid tumors: Eastern Cooperative Oncology Group Study E1281. J Clin Oncol. 2005 Aug 01; 23(22):4897-904. View in: Pubmed

      • Association of short-term ambient air pollution concentrations and ventricular arrhythmias. Am J Epidemiol. 2005 Jun 15; 161(12):1123-32. View in: Pubmed

      • Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation. Am J Surg Pathol. 2005 Apr; 29(4):429-36. View in: Pubmed

      • Under-reporting of alcohol consumption in household surveys: a comparison of quantity-frequency, graduated-frequency and recent recall. Addiction. 2004 Aug; 99(8):1024-33. View in: Pubmed

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      • Personal exposures to particles and their relationships with personal activities for chronic obstructive pulmonary disease patients living in Boston. J Air Waste Manag Assoc. 2004 Feb; 54(2):207-17. View in: Pubmed

      • Association of hospital procedure volume and outcomes in patients with colon cancer at high risk for recurrence. Ann Intern Med. 2003 Oct 21; 139(8):649-57. View in: Pubmed

      • Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol. 2003 Aug 01; 21(15):2912-9. View in: Pubmed

      • Assessing the importance of different exposure metrics and time-activity data to predict 24-H personal PM2.5 exposures. J Toxicol Environ Health A. 2003 Aug 22-Oct 10; 66(16-19):1825-46. View in: Pubmed

      • Influence of body mass index on outcomes and treatment-related toxicity in patients with colon carcinoma. Cancer. 2003 Aug 01; 98(3):484-95. View in: Pubmed

      • Cisplatin, etoposide and either bleomycin or ifosfamide in the treatment of disseminated germ cell tumors: final analysis of an intergroup trial. Cancer. 2003 Apr 15; 97(8):1869-75. View in: Pubmed

      • Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. Ann Surg Oncol. 2003 Apr; 10(3):213-8. View in: Pubmed

      • Thymidylate synthase protein expression in primary colorectal cancer: lack of correlation with outcome and response to fluorouracil in metastatic disease sites. J Clin Oncol. 2003 Mar 01; 21(5):815-9. View in: Pubmed

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      • Outcomes and toxicity in african-american and caucasian patients in a randomized adjuvant chemotherapy trial for colon cancer. J Natl Cancer Inst. 2002 Aug 07; 94(15):1160-7. View in: Pubmed

      • Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297. J Clin Oncol. 2002 Aug 01; 20(15):3270-5. View in: Pubmed

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      • Phase II study of paclitaxel plus gemcitabine in refractory germ cell tumors (E9897): a trial of the Eastern Cooperative Oncology Group. J Clin Oncol. 2002 Apr 01; 20(7):1859-63. View in: Pubmed

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