Robert J. Mayer, MD

Robert J. Mayer, MD

Medical Oncology

Contact Information

Office Phone Number

617-632-3474

Fax

617-632-2260

Biography

Robert J. Mayer, MD

Dr. Mayer received his MD from Harvard Medical School in 1969, and postgraduate training in internal medicine at Mount Sinai Hospital, New York City. After fellowships in hematology and oncology at the National Cancer Institute and Dana-Farber Cancer Institute, he joined Dana-Farber in 1974.

In 1997, he was president of the American Society of Clinical Oncology. Dr. Mayer currently serves as Faculty Vice President for Academic Affairs at Dana-Farber Cancer Institute and Faculty Associate Dean for Admissions at Harvard Medical School.

Researcher

Physician

Faculty Vice President for Academic Affairs
Institute Physician
Stephen B. Kay Family Professor of Medicine, Harvard Medical School

Centers/Programs

Clinical Interests

Gastrointestinal cancers

Board Certification

  • Hematology, 1976
  • Internal Medicine, 1973
  • Medical Oncology, 1975

Fellowship

  • Dana-Farber Cancer Institute, Hematology & Medical Oncology
  • National Cancer Institute, Medical Oncology

Residency

  • Mount Sinai Hospital, Internal Medicine

Medical School

  • Harvard Medical School

Recent Awards

  • Distinguished Achievement Award, American Society of Clinical Oncology 2019
  • Giants of Cancer, Gastrointestinal Cancer 2015
  • Ellen and Stephen Fine Award for Outstanding Teaching in Cancer Medicine, Dana-Farber Cancer Institute 2010
  • Sword of Hope Award, American Cancer Society Massachusetts Division 1995
  • George W. Thorn Award for Outstanding Contribution to Clinical Education 1990

Research

    Multidisciplinary Research in Gastrointestinal Cancer

    Gastrointestinal cancer ranks second only to respiratory cancer in the number of new cases and annual deaths in the United States each year. The term gastrointestinal cancer refers to malignant conditions of the esophagus, stomach, liver, biliary system, pancreas, small bowel, large bowel (i.e., colon and rectum), and anus.The Center for Gastrointestinal Oncology, directed by Dr. Mayer, is a multidisciplinary program to study this group of diseases. Our efforts include the identification and counseling of families at high risk of developing such disorders, the study of medical interventions to prevent the diseases, screening techniques to detect them at a preclinical stage, and the development of innovative treatment plans for diagnosed patients. Such efforts involve the participation of medical, radiation, and surgical oncologists, pathologists, gastroenterologists, social workers, and genetic counselors.The Gastrointestinal Cancer Committee of the Cancer and Leukemia Group B, chaired by Dr. Mayer, is a multi-institutional collaboration supported by the National Cancer Institute. This research organization designs clinical trials conducted at DFCI and elsewhere throughout the United States.We also work regularly with pharmaceutical and biotechnology companies to examine experimental forms of therapy. Clinical trials are available for patients with each of the malignant conditions that gastrointestinal cancer comprises.Our work has been instrumental in studies which have defined optimal post-surgical (i.e., adjuvant) treatment for colon and rectal cancer and newer approaches to localized and advanced pancreatic cancer. In addition, Dr. Mayer has brought such new compounds as cetuximab to Dana-Farber for clinical testing.

    Publications

      • Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders. J Immunother Cancer. 2024 Jan 25; 12(1). View in: Pubmed

      • Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer. JCO Precis Oncol. 2023 01; 7:e2200342. View in: Pubmed

      • Survival in Young-Onset Metastatic Colorectal Cancer: Findings From Cancer and Leukemia Group B (Alliance)/SWOG 80405. J Natl Cancer Inst. 2022 03 08; 114(3):427-435. View in: Pubmed

      • Age and comorbidity association with survival outcomes in metastatic colorectal cancer: CALGB 80405 analysis. J Geriatr Oncol. 2022 05; 13(4):469-479. View in: Pubmed

      • Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance). Clin Cancer Res. 2019 12 15; 25(24):7497-7505. View in: Pubmed

      • Associations of Physical Activity With Survival and Progression in Metastatic Colorectal Cancer: Results From Cancer and Leukemia Group B (Alliance)/SWOG 80405. J Clin Oncol. 2019 10 10; 37(29):2620-2631. View in: Pubmed

      • Reasons of reduced physical activity in preconception and pregnancy. Minerva Med. 2023 02; 114(1):90-91. View in: Pubmed

      • Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial. Eur J Cancer. 2019 04; 111:82-93. View in: Pubmed

      • Dietary Insulin Load and Cancer Recurrence and Survival in Patients With Stage III Colon Cancer: Findings From CALGB 89803 (Alliance). J Natl Cancer Inst. 2019 02 01; 111(2):170-179. View in: Pubmed

      • Safety of trifluridine/tipiracil in an open-label expanded-access program in elderly and younger patients with metastatic colorectal cancer. Cancer Chemother Pharmacol. 2018 12; 82(6):961-969. View in: Pubmed

      • NCCN Guidelines Insights: Colorectal Cancer Screening, Version 1.2018. J Natl Compr Canc Netw. 2018 08; 16(8):939-949. View in: Pubmed

      • Associations of artificially sweetened beverage intake with disease recurrence and mortality in stage III colon cancer: Results from CALGB 89803 (Alliance). PLoS One. 2018; 13(7):e0199244. View in: Pubmed

      • Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine. Cancer Discov. 2018 09; 8(9):1096-1111. View in: Pubmed

      • Grain Intake and Clinical Outcome in Stage III Colon Cancer: Results From CALGB 89803 (Alliance). JNCI Cancer Spectr. 2018 Feb; 2(2):pky017. View in: Pubmed

      • Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance). J Clin Oncol. 2018 04 10; 36(11):1112-1120. View in: Pubmed

      • NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 3.2017. J Natl Compr Canc Netw. 2017 12; 15(12):1465-1475. View in: Pubmed

      • Adjuvant Chemoradiotherapy With Epirubicin, Cisplatin, and Fluorouracil Compared With Adjuvant Chemoradiotherapy With Fluorouracil and Leucovorin After Curative Resection of Gastric Cancer: Results From CALGB 80101 (Alliance). J Clin Oncol. 2017 Nov 10; 35(32):3671-3677. View in: Pubmed

      • Predicted vitamin D status and colon cancer recurrence and mortality in CALGB 89803 (Alliance). Ann Oncol. 2017 Jun 01; 28(6):1359-1367. View in: Pubmed

      • Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome. J Clin Oncol. 2017 Jul 01; 35(19):2165-2172. View in: Pubmed

      • Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer. J Clin Oncol. 2017 Apr 01; 35(10):1086-1095. View in: Pubmed

      • Reply to L. Casadaban et al. J Clin Oncol. 2017 04 20; 35(12):1373-1374. View in: Pubmed

      • Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance). J Clin Oncol. 2016 09 01; 34(25):3047-53. View in: Pubmed

      • CALGB 80403 (Alliance)/E1206: A Randomized Phase II Study of Three Chemotherapy Regimens Plus Cetuximab in Metastatic Esophageal and Gastroesophageal Junction Cancers. J Clin Oncol. 2016 08 10; 34(23):2736-42. View in: Pubmed

      • Safety, Costs, and Efficacy of Rapid Drug Desensitizations to Chemotherapy and Monoclonal Antibodies. J Allergy Clin Immunol Pract. 2016 May-Jun; 4(3):497-504. View in: Pubmed

      • Coffee Intake, Recurrence, and Mortality in Stage III Colon Cancer: Results From CALGB 89803 (Alliance). J Clin Oncol. 2015 Nov 01; 33(31):3598-607. View in: Pubmed

      • Colorectal Cancer Screening, Version 1.2015. J Natl Compr Canc Netw. 2015 Aug; 13(8):959-68; quiz 968. View in: Pubmed

      • Randomized trial of TAS-102 for refractory metastatic colorectal cancer. N Engl J Med. 2015 May 14; 372(20):1909-19. View in: Pubmed

      • Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation. Clin Cancer Res. 2015 Apr 01; 21(7):1583-90. View in: Pubmed

      • Aspirin and COX-2 inhibitor use in patients with stage III colon cancer. J Natl Cancer Inst. 2015 Jan; 107(1):345. View in: Pubmed

      • Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway. J Biol Chem. 2014 Sep 05; 289(36):24944-55. View in: Pubmed

      • Sugar-sweetened beverage intake and cancer recurrence and survival in CALGB 89803 (Alliance). PLoS One. 2014; 9(6):e99816. View in: Pubmed

      • Progress against GI cancer during the American Society of Clinical Oncology's first 50 years. J Clin Oncol. 2014 May 20; 32(15):1521-30. View in: Pubmed

      • Colorectal cancer screening. J Natl Compr Canc Netw. 2013 Dec 01; 11(12):1538-75. View in: Pubmed

      • Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial. J Natl Cancer Inst. 2013 Dec 04; 105(23):1789-98. View in: Pubmed

      • Anal carcinoma: impact of TN category of disease on survival, disease relapse, and colostomy failure in US Gastrointestinal Intergroup RTOG 98-11 phase 3 trial. Int J Radiat Oncol Biol Phys. 2013 Nov 15; 87(4):638-45. View in: Pubmed

      • Impact of physical activity after cancer diagnosis on survival in patients with recurrent colon cancer: Findings from CALGB 89803/Alliance. Clin Colorectal Cancer. 2013 Dec; 12(4):233-8. View in: Pubmed

      • Association of TP53 mutational status and gender with survival after adjuvant treatment for stage III colon cancer: results of CALGB 89803. Clin Cancer Res. 2013 Oct 15; 19(20):5777-87. View in: Pubmed

      • Reply to A. Grothey et al and R.S. Midgley et al. J Clin Oncol. 2013 Apr 20; 31(12):1612-3. View in: Pubmed

      • Phase I study of sorafenib in combination with everolimus (RAD001) in patients with advanced neuroendocrine tumors. Cancer Chemother Pharmacol. 2013 May; 71(5):1241-6. View in: Pubmed

      • Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin. J Clin Oncol. 2012 Dec 10; 30(35):4344-51. View in: Pubmed

      • Dietary glycemic load and cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. J Natl Cancer Inst. 2012 Nov 21; 104(22):1702-11. View in: Pubmed

      • Clinical practice guidelines for cancer care: utilization and expectations of the practicing oncologist. J Oncol Pract. 2012 Nov; 8(6):350-3, 2 p following 353. View in: Pubmed

      • Oxaliplatin as part of adjuvant therapy for colon cancer: more complicated than once thought. J Clin Oncol. 2012 Sep 20; 30(27):3325-7. View in: Pubmed

      • Perspective: a culture of respect, part 1: the nature and causes of disrespectful behavior by physicians. Acad Med. 2012 Jul; 87(7):845-52. View in: Pubmed

      • Perspective: a culture of respect, part 2: creating a culture of respect. Acad Med. 2012 Jul; 87(7):853-8. View in: Pubmed

      • Disability in women suffering from interstitial cystitis/bladder pain syndrome. BJU Int. 2013 Jan; 111(1):114-21. View in: Pubmed

      • Locally advanced anaplastic pancreatic adenocarcinoma with initial response to FOLFIRINOX and rapid progression after five months. Pancreatology. 2012 Jan-Feb; 12(1):35-8. View in: Pubmed

      • Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803. Clin Cancer Res. 2012 Feb 01; 18(3):890-900. View in: Pubmed

      • Relationship between statin use and colon cancer recurrence and survival: results from CALGB 89803. J Natl Cancer Inst. 2011 Oct 19; 103(20):1540-51. View in: Pubmed

      • Documenting the natural history of patients with resected stage II adenocarcinoma of the colon after random assignment to adjuvant treatment with edrecolomab or observation: results from CALGB 9581. J Clin Oncol. 2011 Aug 10; 29(23):3146-52. View in: Pubmed

      • Microsatellite instability and loss of heterozygosity at chromosomal location 18q: prospective evaluation of biomarkers for stages II and III colon cancer--a study of CALGB 9581 and 89803. J Clin Oncol. 2011 Aug 10; 29(23):3153-62. View in: Pubmed

      • Postoperative adjuvant chemoradiation for gastric or gastroesophageal junction (GEJ) adenocarcinoma using epirubicin, cisplatin, and infusional (CI) 5-FU (ECF) before and after CI 5-FU and radiotherapy (CRT) compared with bolus 5-FU/LV before and after CRT: Intergroup trial CALGB 80101. J Clin Oncol. 2011 May 20; 29(15_suppl):4003. View in: Pubmed

      • Long-term update of U.S. GI intergroup RTOG 98-11 phase III trial for anal carcinoma: Disease-free and overall survival with RT+5FU-mitomycin versus RT+5FU-cisplatin. J Clin Oncol. 2011 May 20; 29(15_suppl):4005. View in: Pubmed

      • Long-term update of U.S. GI Intergroup RTOG 98-11 phase III trial for anal carcinoma: Comparison of concurrent chemoradiation with 5FU-mitomycin versus 5FU-cisplatin for disease-free and overall survival. J Clin Oncol. 2011 Feb; 29(4_suppl):367. View in: Pubmed

      • A phase 2 trial of gemcitabine, 5-fluorouracil, and radiation therapy in locally advanced nonmetastatic pancreatic adenocarcinoma : cancer and Leukemia Group B (CALGB) 80003. Cancer. 2011 Jun 15; 117(12):2620-8. View in: Pubmed

      • Prognostic factors derived from a prospective database dictate clinical biology of anal cancer: the intergroup trial (RTOG 98-11). Cancer. 2010 Sep 01; 116(17):4007-13. View in: Pubmed

      • Multivitamin use is not associated with cancer recurrence or survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol. 2010 Oct 01; 28(28):4354-63. View in: Pubmed

      • Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303). J Clin Oncol. 2010 Aug 01; 28(22):3617-22. View in: Pubmed

      • By the way, doctor. I read that President Obama had a virtual colonoscopy. Is this the colon cancer screening test that everybody should be getting instead of a regular colonoscopy? I thought it was kind of experimental. Harv Health Lett. 2010 Jun; 35(8):8. View in: Pubmed

      • A step forward in the treatment of advanced biliary tract cancer. N Engl J Med. 2010 Apr 08; 362(14):1335-7. View in: Pubmed

      • The American Society of Clinical Oncology Cancer Foundation Grants Program: a 25-year report and a look toward the future. J Clin Oncol. 2010 Mar 20; 28(9):1616-21. View in: Pubmed

      • NCCN clinical practice guidelines in oncology. Colorectal cancer screening. J Natl Compr Canc Netw. 2010 Jan; 8(1):8-61. View in: Pubmed

      • KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803. Clin Cancer Res. 2009 Dec 01; 15(23):7322-9. View in: Pubmed

      • Randomized phase II study of gemcitabine administered at a fixed dose rate or in combination with cisplatin, docetaxel, or irinotecan in patients with metastatic pancreatic cancer: CALGB 89904. J Clin Oncol. 2009 Nov 20; 27(33):5506-12. View in: Pubmed

      • KRAS mutation, cancer recurrence, and patient survival in stage III colon cancer: Findings from CALGB 89803. J Clin Oncol. 2009 May 20; 27(15_suppl):4037. View in: Pubmed

      • Presence of 18q loss of heterozygosity (LOH) and disease-free and overall survival in stage II colon cancer: CALGB Protocol 9581. J Clin Oncol. 2009 May 20; 27(15_suppl):4012. View in: Pubmed

      • By the way, doctor. We have screening tests for other cancers. How about pancreatic cancer? Harv Health Lett. 2009 May; 34(7):1. View in: Pubmed

      • Sexual functioning, catastrophizing, depression, and pain, as predictors of quality of life in women with interstitial cystitis/painful bladder syndrome. Urology. 2009 May; 73(5):987-92. View in: Pubmed

      • A compendium of potential biomarkers of pancreatic cancer. PLoS Med. 2009 Apr 07; 6(4):e1000046. View in: Pubmed

      • p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803. Clin Cancer Res. 2009 Mar 15; 15(6):2116-22. View in: Pubmed

      • Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803. J Clin Oncol. 2009 Apr 10; 27(11):1814-21. View in: Pubmed

      • Targeted therapy for advanced colorectal cancer--more is not always better. N Engl J Med. 2009 Feb 05; 360(6):623-5. View in: Pubmed

      • Weekly docetaxel, cisplatin, and irinotecan (TPC): results of a multicenter phase II trial in patients with metastatic esophagogastric cancer. Ann Oncol. 2009 Mar; 20(3):475-80. View in: Pubmed

      • US intergroup anal carcinoma trial: tumor diameter predicts for colostomy. J Clin Oncol. 2009 Mar 01; 27(7):1116-21. View in: Pubmed

      • Clinical cancer advances 2008: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology. J Clin Oncol. 2009 Feb 10; 27(5):812-26. View in: Pubmed

      • Impact of body mass index and weight change after treatment on cancer recurrence and survival in patients with stage III colon cancer: findings from Cancer and Leukemia Group B 89803. J Clin Oncol. 2008 Sep 01; 26(25):4109-15. View in: Pubmed

      • Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study. J Clin Oncol. 2008 Oct 01; 26(28):4603-9. View in: Pubmed

      • Local excision of distal rectal cancer: an update of cancer and leukemia group B 8984. Dis Colon Rectum. 2008 Aug; 51(8):1185-91; discussion 1191-4. View in: Pubmed

      • Association of family history with cancer recurrence and survival among patients with stage III colon cancer. JAMA. 2008 Jun 04; 299(21):2515-23. View in: Pubmed

      • The impact of smoking on cancer recurrence and survival in patients with stage III colon cancer: Findings from intergroup trial CALGB 89803. J Clin Oncol. 2008 May 20; 26(15_suppl):4039. View in: Pubmed

      • Induction therapy for poor-prognosis anal canal carcinoma: a phase II study of the cancer and Leukemia Group B (CALGB 9281). J Clin Oncol. 2008 Jul 01; 26(19):3229-34. View in: Pubmed

      • Systemic treatment of colorectal cancer. Gastroenterology. 2008 May; 134(5):1296-310. View in: Pubmed

      • By the way, doctor. Cancer of the small intestine. Harv Health Lett. 2008 May; 33(7):7. View in: Pubmed

      • Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial. JAMA. 2008 Apr 23; 299(16):1914-21. View in: Pubmed

      • Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781. J Clin Oncol. 2008 Mar 01; 26(7):1086-92. View in: Pubmed

      • Followup of patients with interstitial cystitis responsive to treatment with intravesical bacillus Calmette-Guerin or placebo. J Urol. 2008 Feb; 179(2):552-5. View in: Pubmed

      • Clinical cancer advances 2007: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology. J Clin Oncol. 2008 Jan 10; 26(2):313-25. View in: Pubmed

      • A phase II prospective multi-institutional trial of adjuvant active specific immunotherapy following curative resection of colorectal cancer hepatic metastases: cancer and leukemia group B study 89903. Ann Surg Oncol. 2008 Jan; 15(1):158-64. View in: Pubmed

      • Should capecitabine replace infusional fluorouracil and leucovorin when combined with oxaliplatin in metastatic colorectal cancer? J Clin Oncol. 2007 Sep 20; 25(27):4165-7. View in: Pubmed

      • Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer. JAMA. 2007 Aug 15; 298(7):754-64. View in: Pubmed

      • Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803. J Clin Oncol. 2007 Aug 10; 25(23):3456-61. View in: Pubmed

      • Did patients with interstitial cystitis who failed to respond to initial treatment with bacillus Calmette-Guerin or placebo in a randomized clinical trial benefit from a second course of open label bacillus Calmette-Guerin? J Urol. 2007 Sep; 178(3 Pt 1):886-90. View in: Pubmed

      • Phase II study of FOLFOX, bevacizumab and erlotinib as first-line therapy for patients with metastatic colorectal cancer. Ann Oncol. 2007 Jul; 18(7):1185-9. View in: Pubmed

      • Sexual function is a determinant of poor quality of life for women with treatment refractory interstitial cystitis. J Urol. 2007 May; 177(5):1832-6. View in: Pubmed

      • Adjuvant treatment of colorectal cancer. CA Cancer J Clin. 2007 May-Jun; 57(3):168-85. View in: Pubmed

      • Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer. Cancer Chemother Pharmacol. 2007 Oct; 60(5):661-70. View in: Pubmed

      • Clinical cancer advances 2006: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology. J Clin Oncol. 2007 Jan 01; 25(1):146-62. View in: Pubmed

      • Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. J Clin Oncol. 2006 Oct 20; 24(30):4914-21. View in: Pubmed

      • The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer. Gastroenterology. 2007 Jan; 132(1):127-38. View in: Pubmed

      • Systemic treatment of patients who have colorectal cancer and inflammatory bowel disease. Gastroenterol Clin North Am. 2006 Sep; 35(3):713-27. View in: Pubmed

      • Development of glomerulations in younger women with interstitial cystitis. Urology. 2006 Aug; 68(2):253-6. View in: Pubmed

      • Phase III trial of fluorouracil-based chemotherapy regimens plus radiotherapy in postoperative adjuvant rectal cancer: GI INT 0144. J Clin Oncol. 2006 Aug 01; 24(22):3542-7. View in: Pubmed

      • Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol. 2006 Aug 01; 24(22):3535-41. View in: Pubmed

      • ECOG E3201: Intergroup randomized phase III study of postoperative irinotecan, 5- fluorouracil (FU), leucovorin (LV) (FOLFIRI) vs oxaliplatin, FU/LV (FOLFOX) vs FU/LV for patients (pts) with stage II/ III rectal cancer receiving either pre or postoperative radiation (RT)/ FU. J Clin Oncol. 2006 Jun 20; 24(18_suppl):3526. View in: Pubmed

      • Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, 5-fluorouracil and leucovorin in stage III colon cancer. J Clin Oncol. 2006 Jun 20; 24(18_suppl):10003. View in: Pubmed

      • Intergroup RTOG 98-11: A phase III randomized study of 5-fluorouracil (5-FU), mitomycin, and radiotherapy versus 5-fluorouracil, cisplatin and radiotherapy in carcinoma of the anal canal. J Clin Oncol. 2006 Jun 20; 24(18_suppl):4009. View in: Pubmed

      • Cancer and leukemia group B gastrointestinal cancer committee. Clin Cancer Res. 2006 Jun 01; 12(11 Pt 2):3589s-95s. View in: Pubmed

      • Fifty years of clinical research by the leukemia committee of the cancer and leukemia group B. Clin Cancer Res. 2006 Jun 01; 12(11 Pt 2):3556s-63s. View in: Pubmed

      • Phase I/II study of preoperative oxaliplatin, fluorouracil, and external-beam radiation therapy in patients with locally advanced rectal cancer: Cancer and Leukemia Group B 89901. J Clin Oncol. 2006 Jun 01; 24(16):2557-62. View in: Pubmed

      • Colorectal Cancer Screening Clinical Practice Guidelines. J Natl Compr Canc Netw. 2006 Apr; 4(4):384-420. View in: Pubmed

      • Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461. Blood. 2006 Jul 01; 108(1):63-73. View in: Pubmed

      • Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481). J Clin Oncol. 2006 Mar 20; 24(9):1395-403. View in: Pubmed

      • Analysis of micrometastatic disease in sentinel lymph nodes from resectable colon cancer: results of Cancer and Leukemia Group B Trial 80001. J Clin Oncol. 2006 Feb 20; 24(6):878-83. View in: Pubmed

      • Clinical Cancer Advances 2005: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology. J Clin Oncol. 2006 Jan 01; 24(1):190-205. View in: Pubmed

      • Phase III study of fluorouracil, leucovorin, and levamisole in high-risk stage II and III colon cancer: final report of Intergroup 0089. J Clin Oncol. 2005 Dec 01; 23(34):8671-8. View in: Pubmed

      • Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol. 2005 Dec 01; 23(34):8706-12. View in: Pubmed

      • A phase II trial of irinotecan in patients with previously untreated advanced esophageal and gastric adenocarcinoma. Dig Dis Sci. 2005 Dec; 50(12):2218-23. View in: Pubmed

      • Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study. J Clin Oncol. 2005 Aug 20; 23(24):5705-17. View in: Pubmed

      • Influence of regular aspirin use on survival for patients with stage III colon cancer: Findings from Intergroup trial CALGB 89803. J Clin Oncol. 2005 Jun; 23(16_suppl):3530. View in: Pubmed

      • The impact of physical activity on patients with stage III colon cancer: Findings from Intergroup trial CALGB 89803. J Clin Oncol. 2005 Jun; 23(16_suppl):3534. View in: Pubmed

      • Factors predicting willingness to participate in cancer genetic epidemiologic research. J Clin Oncol. 2005 Jun; 23(16_suppl):6007. View in: Pubmed

      • Consistent response to treatment with cetuximab monotherapy in patients with metastatic colorectal cancer. J Clin Oncol. 2005 Jun; 23(16_suppl):3536. View in: Pubmed

      • Analysis of EGFR status in metastatic colorectal cancer patients treated with cetuximab monotherapy. J Clin Oncol. 2005 Jun; 23(16_suppl):3595. View in: Pubmed

      • A randomized controlled trial of intravesical bacillus calmette-guerin for treatment refractory interstitial cystitis. J Urol. 2005 Apr; 173(4):1186-91. View in: Pubmed

      • Phase III Southwest Oncology Group 9415/Intergroup 0153 randomized trial of fluorouracil, leucovorin, and levamisole versus fluorouracil continuous infusion and levamisole for adjuvant treatment of stage III and high-risk stage II colon cancer. J Clin Oncol. 2005 Mar 20; 23(9):1819-25. View in: Pubmed

      • Systemic therapy for colorectal cancer. N Engl J Med. 2005 Feb 03; 352(5):476-87. View in: Pubmed

      • Epigenetic inactivation of RUNX3 in microsatellite unstable sporadic colon cancers. Int J Cancer. 2004 Dec 10; 112(5):754-9. View in: Pubmed

      • Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study. J Clin Oncol. 2005 Jan 20; 23(3):482-93. View in: Pubmed

      • APC promoter hypermethylation contributes to the loss of APC expression in colorectal cancers with allelic loss on 5q. Cancer Biol Ther. 2004 Oct; 3(10):960-4. View in: Pubmed

      • Sentinel node staging of resectable colon cancer: results of a multicenter study. Ann Surg. 2004 Oct; 240(4):624-8; discussion 628-30. View in: Pubmed

      • Lack of efficacy of streptozocin and doxorubicin in patients with advanced pancreatic endocrine tumors. Am J Clin Oncol. 2004 Oct; 27(5):485-8. View in: Pubmed

      • Activity of cetuximab in patients with colorectal cancer refractory to both irinotecan and oxaliplatin. J Clin Oncol. 2004 Jul 15; 22(14_suppl):3510. View in: Pubmed

      • A phase I/II study of preoperative oxaliplatin (O), 5-fluorouracil (5-FU), and external beam radiation therapy (XRT) in locally advanced rectal cancer: CALGB 89901. J Clin Oncol. 2004 Jul 15; 22(14_suppl):3560. View in: Pubmed

      • Irinotecan plus fluorouracil/leucovorin (IFL) versus fluorouracil/leucovorin alone (FL) in stage III colon cancer (intergroup trial CALGB C89803). J Clin Oncol. 2004 Jul 15; 22(14_suppl):3500. View in: Pubmed

      • Post-remission therapy with 4 cycles of intermediate (I) or high-dose (HD) cytarabine (AC) or autologous hematopoietic stem cell transplantation (ASCT) for acute myeloid leukemia (AML) patients <60 years with normal cytogenetics: A Cancer and Leukemia Group B (CALGB) Study. J Clin Oncol. 2004 Jul 15; 22(14_suppl):6542. View in: Pubmed

      • A randomized phase II study of gemcitabine/cisplatin, gemcitabine fixed dose rate infusion, gemcitabine/docetaxel, or gemcitabine/irinotecan in patients with metastatic pancreatic cancer (CALGB 89904). J Clin Oncol. 2004 Jul 15; 22(14_suppl):4011. View in: Pubmed

      • Two steps forward in the treatment of colorectal cancer. N Engl J Med. 2004 Jun 03; 350(23):2406-8. View in: Pubmed

      • Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. Cancer Res. 2004 May 01; 64(9):3014-21. View in: Pubmed

      • Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis. J Clin Oncol. 2004 May 15; 22(10):1785-96. View in: Pubmed

      • Gastrointestinal cancer in older patients. Semin Oncol. 2004 Apr; 31(2):206-19. View in: Pubmed

      • Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): results from CALGB 8461. J Clin Oncol. 2004 Mar 15; 22(6):1087-94. View in: Pubmed

      • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol. 2004 Apr 01; 22(7):1201-8. View in: Pubmed

      • Differences in prognostic factors and outcomes in African Americans and whites with acute myeloid leukemia. Blood. 2004 Jun 01; 103(11):4036-42. View in: Pubmed

      • Impact of body mass index on outcomes and treatment-related toxicity in patients with stage II and III rectal cancer: findings from Intergroup Trial 0114. J Clin Oncol. 2004 Feb 15; 22(4):648-57. View in: Pubmed

      • Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer. Cancer Biol Ther. 2004 Jan; 3(1):73-8. View in: Pubmed

      • Core binding factor acute myeloid leukemia. Cancer and Leukemia Group B (CALGB) Study 8461. Ann Hematol. 2004; 83 Suppl 1:S84-5. View in: Pubmed

      • A phase II study of docetaxel in patients with metastatic carcinoid tumors. Cancer Invest. 2004; 22(3):353-9. View in: Pubmed

      • Impact of hospital procedure volume on surgical operation and long-term outcomes in high-risk curatively resected rectal cancer: findings from the Intergroup 0114 Study. J Clin Oncol. 2004 Jan 01; 22(1):166-74. View in: Pubmed

      • Esophageal cancer. N Engl J Med. 2003 Dec 04; 349(23):2241-52. View in: Pubmed

      • Association of hospital procedure volume and outcomes in patients with colon cancer at high risk for recurrence. Ann Intern Med. 2003 Oct 21; 139(8):649-57. View in: Pubmed

      • Analysis of surgical salvage after failure of primary therapy in rectal cancer: results from Intergroup Study 0114. J Clin Oncol. 2003 Oct 01; 21(19):3623-8. View in: Pubmed

      • Influence of body mass index on outcomes and treatment-related toxicity in patients with colon carcinoma. Cancer. 2003 Aug 01; 98(3):484-95. View in: Pubmed

      • Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol. 2003 Aug 01; 21(15):2912-9. View in: Pubmed

      • Follow-up strategies after curative resection of colorectal cancer. Semin Oncol. 2003 Jun; 30(3):349-60. View in: Pubmed

      • Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. Ann Surg Oncol. 2003 Apr; 10(3):213-8. View in: Pubmed

      • Characterization of sporadic colon cancer by patterns of genomic instability. Cancer Res. 2003 Apr 01; 63(7):1608-14. View in: Pubmed

      • Impact of diabetes mellitus on outcomes in patients with colon cancer. J Clin Oncol. 2003 Feb 01; 21(3):433-40. View in: Pubmed

      • Cancer and leukemia group B (CALGB) 89805: phase II chemoradiation trial using gemcitabine in patients with locoregional adenocarcinoma of the pancreas. Int J Gastrointest Cancer. 2003; 34(2-3):107-16. View in: Pubmed

      • A phase II study of modified deGramont 5-fluorouracil, leucovorin, and oxaliplatin in previously treated patients with metastatic colorectal cancer. Cancer Invest. 2003; 21(4):505-11. View in: Pubmed

      • Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461. Int J Oncol. 2002 Nov; 21(5):1041-51. View in: Pubmed

      • Acute diarrhea during adjuvant therapy for rectal cancer: a detailed analysis from a randomized intergroup trial. Int J Radiat Oncol Biol Phys. 2002 Oct 01; 54(2):409-13. View in: Pubmed

      • Impact of T and N substage on survival and disease relapse in adjuvant rectal cancer: a pooled analysis. Int J Radiat Oncol Biol Phys. 2002 Oct 01; 54(2):386-96. View in: Pubmed

      • A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer. Cancer J. 2002 Sep-Oct; 8(5):395-9. View in: Pubmed

      • Outcomes and toxicity in african-american and caucasian patients in a randomized adjuvant chemotherapy trial for colon cancer. J Natl Cancer Inst. 2002 Aug 07; 94(15):1160-7. View in: Pubmed

      • Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood. 2002 Dec 15; 100(13):4325-36. View in: Pubmed

      • A phase II trial of gemcitabine in patients with advanced hepatocellular carcinoma. Cancer. 2002 Jun 15; 94(12):3186-91. View in: Pubmed

      • Adjuvant therapy in rectal cancer: analysis of stage, sex, and local control--final report of intergroup 0114. J Clin Oncol. 2002 Apr 01; 20(7):1744-50. View in: Pubmed

      • Surveillance for second primary colorectal cancer after adjuvant chemotherapy: an analysis of Intergroup 0089. Ann Intern Med. 2002 Feb 19; 136(4):261-9. View in: Pubmed

      • Merkel cell carcinoma. J Clin Oncol. 2002 Jan 15; 20(2):588-98. View in: Pubmed

      • A Phase II study of gemcitabine and docetaxel in patients with metastatic pancreatic carcinoma. Cancer. 2002 Jan 01; 94(1):97-103. View in: Pubmed

      • Oral versus intravenous fluoropyrimidines for advanced colorectal cancer: by either route, it's all the same. J Clin Oncol. 2001 Nov 01; 19(21):4093-6. View in: Pubmed

      • Fluorouracil modulation in colorectal cancer: lack of improvement with N -phosphonoacetyl- l -aspartic acid or oral leucovorin or interferon, but enhanced therapeutic index with weekly 24-hour infusion schedule--an Eastern Cooperative Oncology Group/Cancer and Leukemia Group B Study. J Clin Oncol. 2001 May 01; 19(9):2413-21. View in: Pubmed

      • CALGB 9380: a prospective trial of the feasibility of thoracoscopy/laparoscopy in staging esophageal cancer. Ann Thorac Surg. 2001 Apr; 71(4):1073-9. View in: Pubmed

      • Phase II study of oral eniluracil, 5-fluorouracil, and leucovorin in patients with advanced colorectal carcinoma. Cancer. 2001 Apr 01; 91(7):1256-63. View in: Pubmed

      • Oxaliplatin-induced Evan's syndrome. Br J Cancer. 2001 Feb 02; 84(3):441. View in: Pubmed

      • Efficacy of neo- and adjuvant treatment modalities in gastrointestinal cancer patients. Swiss Surg. 2001; 7(6):239-42. View in: Pubmed

      • Attitudes and practices among pediatric oncologists regarding end-of-life care: results of the 1998 American Society of Clinical Oncology survey. J Clin Oncol. 2001 Jan 01; 19(1):205-12. View in: Pubmed

      • Impact of number of nodes retrieved on outcome in patients with rectal cancer. J Clin Oncol. 2001 Jan 01; 19(1):157-63. View in: Pubmed

      • Attitudes and practices of U.S. oncologists regarding euthanasia and physician-assisted suicide. Ann Intern Med. 2000 Oct 03; 133(7):527-32. View in: Pubmed

      • Moving beyond fluorouracil for colorectal cancer. N Engl J Med. 2000 Sep 28; 343(13):963-4. View in: Pubmed

      • Diagnostic dilemmas in oncology. Case 3. Metastatic ovarian cancer simulating colon cancer. J Clin Oncol. 2000 Sep; 18(17):3189-92. View in: Pubmed

      • Anal carcinoma: histology, staging, epidemiology, treatment. Curr Opin Oncol. 2000 Jul; 12(4):345-52. View in: Pubmed

      • Chemoprevention of colorectal cancer. N Engl J Med. 2000 Jun 29; 342(26):1960-8. View in: Pubmed

      • Carcinoma of the anal canal. N Engl J Med. 2000 Mar 16; 342(11):792-800. View in: Pubmed

      • A phase I study of gemcitabine and docetaxel in patients with metastatic solid tumors. Cancer. 2000 Jan 01; 88(1):180-5. View in: Pubmed

      • Patients with t(8;21)(q22;q22) and acute myeloid leukemia have superior failure-free and overall survival when repetitive cycles of high-dose cytarabine are administered. J Clin Oncol. 1999 Dec; 17(12):3767-75. View in: Pubmed

      • Sphincter-sparing treatment for distal rectal adenocarcinoma. Ann Surg Oncol. 1999 Jul-Aug; 6(5):433-41. View in: Pubmed

      • Carcinoid tumors. N Engl J Med. 1999 Mar 18; 340(11):858-68. View in: Pubmed

      • Third International Conference on Biology, Prevention and Treatment of Gastrointestinal Malignancies. Cologne, 23-26 September 1998. Ann Oncol. 1999 Mar; 10(3):281-7. View in: Pubmed

      • Multidisciplinary gastrointestinal cancer clinic: abdominal radiologist as active participant. Acad Radiol. 1998 Oct; 5(10):694-7. View in: Pubmed

      • Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype. Cancer Res. 1998 Sep 15; 58(18):4173-9. View in: Pubmed

      • The state of the society: a year of continued growth. J Clin Oncol. 1998 Sep; 16(9):3192-8. View in: Pubmed

      • Comparison of psychosocial adaptation of advanced stage Hodgkin's disease and acute leukemia survivors. Cancer and Leukemia Group B. Ann Oncol. 1998 Mar; 9(3):297-306. View in: Pubmed

      • Cancer care during the last phase of life. J Clin Oncol. 1998; 5:1986-1996. View in: Pubmed

      • Adult patients with de novo acute myeloid leukemia and t(9; 11)(p22; q23) have a superior outcome to patients with other translocations involving band 11q23: a cancer and leukemia group B study. Blood. 1997 Dec 01; 90(11):4532-8. View in: Pubmed

      • Quality of life for adult leukemia survivors treated on clinical trials of Cancer and Leukemia Group B during the period 1971-1988: predictors for later psychologic distress. Cancer. 1997 Nov 15; 80(10):1936-44. View in: Pubmed

      • Winning the war on cancer. N Engl J Med. 1997 Sep 25; 337(13):935; author reply 937-8. View in: Pubmed

      • Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study. J Clin Oncol. 1997 May; 15(5):1786-95. View in: Pubmed

      • Extramedullary leukemia adversely affects hematologic complete remission rate and overall survival in patients with t(8;21)(q22;q22): results from Cancer and Leukemia Group B 8461. J Clin Oncol. 1997 Feb; 15(2):466-75. View in: Pubmed

      • Colorectal cancer screening: clinical guidelines and rationale. Gastroenterology. 1997 Feb; 112(2):594-642. View in: Pubmed

      • Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer. J Clin Oncol. 1997 Jan; 15(1):246-50. View in: Pubmed

      • Acute myeloid leukemia-type chemotherapy for newly diagnosed patients without antecedent cytopenias having myelodysplastic syndrome as defined by French-American-British criteria: a Cancer and Leukemia Group B Study. J Clin Oncol. 1996 Sep; 14(9):2486-94. View in: Pubmed

      • The status of the medical oncology workforce a report from the ad hoc committee of the American Society of Clinical Oncology. J Clin Oncol. 1996; 14:2612-2621. View in: Pubmed

      • Adjuvant chemotherapy for colon and rectal cancer. Semin Oncol. 1995 Oct; 22(5):472-87. View in: Pubmed

      • Summary of the Second International Conference on Biology, Prevention and Treatment of Gastrointestinal Malignancies. Ann Oncol. 1995 Sep; 6(7):645-9. View in: Pubmed

      • Gastric carcinoma. N Engl J Med. 1995 Jul 06; 333(1):32-41. View in: Pubmed

      • Morphologic characteristics of erythroleukemia (acute myeloid leukemia; FAB-M6): a CALGB study. Am J Hematol. 1995 May; 49(1):29-38. View in: Pubmed

      • Clinical pharmacology of cytarabine in patietns with acute myeloid leukemia: a Cancer and Leukemia Group B study. Cancer Chemother and Pharmacol. 1995; 36:425-430. View in: Pubmed

      • Clinical pharmacology of cytarabine in patients with acute myeloid leukemia: a Cancer and Leukemia Group B study. Cancer Chemother and Pharmacol. 1995; 36:425-430. View in: Pubmed

      • A prospective evaluation of hepatic resection for colorectal carcinoma metastases to the liver: follow-up report. J Hepatic Biliary Pancreatic Surg. 1995; 2:122-125. View in: Pubmed

      • Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B. N Engl J Med. 1994 Oct 06; 331(14):896-903. View in: Pubmed

      • Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med. 1994 Aug 25; 331(8):502-7. View in: Pubmed

      • The use of serologic tumor markers in gastrointestinal malignancies. Hematol Oncol Clin North Am. 1994 Jun; 8(3):533-53. View in: Pubmed

      • Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia. Blood. 1994 Mar 15; 83(6):1603-11. View in: Pubmed

      • Cigarette smoking and risk of acute leukemia: associations with morphology and cytogenetic abnormalities in bone marrow. J Natl Cancer Inst. 1993 Dec 15; 85(24):1994-2003. View in: Pubmed

      • Primary central nervous system lymphoma. Ann Intern Med. 1993 Dec 01; 119(11):1093-104. View in: Pubmed

      • Preoperative and postoperative combination chemotherapy for potentially resectable gastric carcinoma. J Natl Cancer Inst. 1993 Nov 17; 85(22):1839-44. View in: Pubmed

      • Neoadjuvant therapy for unresectable pancreatic adenocarcinoma. Arch Surg. 1993 May; 128(5):559-64. View in: Pubmed

      • Recombinant human gamma interferon administered by continuous intravenous infusion in acute myelogenous leukemia and myelodysplastic syndromes. Am J Clin Oncol. 1993 Apr; 16(2):159-63. View in: Pubmed

      • Overview: the changing nature of esophageal cancer. Chest. 1993 Apr; 103(4 Suppl):404S-405S. View in: Pubmed

      • Treatment of the newly diagnosed adult with de novo acute myeloid leukemia. Hematol Oncol Clin North Am. 1993 Feb; 7(1):47-64. View in: Pubmed

      • The approach to the elderly patient with acute myeloid leukemia. Hematol Oncol Clin North Am. 1993 Feb; 7(1):65-79. View in: Pubmed

      • Adjuvant Chemotherapy for Colon and Rectal Cancer. Semin Radiat Oncol. 1993 Jan; 3(1):29-41. View in: Pubmed

      • Some considerations concerning the dose and schedule of 5FU and leucovorin: toxicities of two dose schedules from the intergroup colon adjuvant trial (INT-0089). Adv Exp Med Biol. 1993; 339:51-4; discussion 55-6. View in: Pubmed

      • Chemotherapy for metastatic colorectal cancer. Cancer. 1992 Sep 01; 70(5 Suppl):1414-24. View in: Pubmed

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      • Etoposide, doxorubicin, and cisplatin chemotherapy for advanced gastric adenocarcinoma: results of a phase II trial. J Clin Oncol. 1992 Apr; 10(4):536-40. View in: Pubmed

      • Intensive post-remission therapy with Ara-C in adults with acute myeloid leukemia: initial results of a CALGB phase III trial. The Cancer and Leukemia Group B. Leukemia. 1992; 6 Suppl 2:66-7. View in: Pubmed

      • Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. J Clin Oncol. 1992; 10:549-557. View in: Pubmed

      • Preservation of sphincter function in rectal carcinoma by a multimodality treatment approach. Surg Clin N Am. 1992; 1:137-145. View in: Pubmed

      • Fluorouracil and high-dose leucovorin in previously untreated patients with advanced adenocarcinoma of the pancreas: results of a phase II trial. J Clin Oncol. 1991 Dec; 9(12):2128-33. View in: Pubmed

      • Systemic therapy for colorectal cancer: an overview. Semin Oncol. 1991 Oct; 18(5 Suppl 7):62-6. View in: Pubmed

      • A prospective evaluation of hepatic resection for colorectal carcinoma metastases to the liver: Gastrointestinal Tumor Study Group Protocol 6584. J Clin Oncol. 1991 Jul; 9(7):1105-12. View in: Pubmed

      • Training in medical oncology: regaining the luster. J Natl Cancer Inst. 1991 Jun 19; 83(12):806-7. View in: Pubmed

      • A pilot study of sphincter-sparing management of adenocarcinoma of the rectum. Arch Surg. 1991 Jun; 126(6):696-701; discussion 701-2. View in: Pubmed

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      • Phase III trial of brief intensive treatment of adult acute lymphocytic leukemia comparing daunorubicin and mitoxantrone: a CALGB Study. Leukemia. 1991 May; 5(5):425-31. View in: Pubmed

      • Prophylaxis of bacterial infections with ciprofloxacin in patients undergoing bone marrow transplantation. Transplantation. 1991 Mar; 51(3):630-6. View in: Pubmed

      • Simultaneous administration of granulocyte-macrophage colony-stimulating factor and cytosine arabinoside for the treatment of relapsed acute myeloid leukemia. Leukemia. 1991 Mar; 5(3):230-8. View in: Pubmed

      • A phase I study of intermittent continuous infusion high dose cytosine arabinoside for acute leukemia. Leukemia. 1990 Dec; 4(12):843-7. View in: Pubmed

      • The unique aspects of acute promyelocytic leukemia. J Clin Oncol. 1990 Nov; 8(11):1913-21. View in: Pubmed

      • Treatment of relapsed and refractory acute myeloid leukemia with diaziquone and mitoxantrone: a CALGB phase I study. Am J Hematol. 1990 Oct; 35(2):80-3. View in: Pubmed

      • Intensive chemotherapy versus allogeneic bone marrow transplantation in first-remission acute myeloid leukemia. Bone Marrow Transplant. 1990 Jul; 6 Suppl 1:48-51. View in: Pubmed

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      • Pregnancy and leukemia. Semin Oncol. 1989 Oct; 16(5):388-96. View in: Pubmed

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      • The medical course of cancer patients with fever and neutropenia. Clinical identification of a low-risk subgroup at presentation. Arch Intern Med. 1988 Dec; 148(12):2561-8. View in: Pubmed

      • Value of a routine follow-up endoscopy program for the detection of recurrent colorectal carcinoma. Am J Gastroenterol. 1988 Dec; 83(12):1355-60. View in: Pubmed

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      • Adjuvant therapy in rectal cancer: a protocol proposal. Semin Oncol. 1985 Sep; 12(3 Suppl 4):116-20. View in: Pubmed

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      • Acute lymphoblastic leukemia in adults. Ann Intern Med. 1984 Oct; 101(4):552-4. View in: Pubmed

      • B cell origin of non-T cell acute lymphoblastic leukemia. A model for discrete stages of neoplastic and normal pre-B cell differentiation. J Clin Invest. 1984 Aug; 74(2):332-40. View in: Pubmed

      • Patterns of failure after surgical cure of large liver tumors. A change in the proximate cause of death and a need for effective systemic adjuvant therapy. Am J Surg. 1984 Apr; 147(4):554-9. View in: Pubmed

      • Adjuvant therapy for colon cancer: Results of a prospectively randomized trial. N Engl J Med. 1984; 310:737-743. View in: Pubmed

      • Phase II study of methyl-CCNU, vincristine, 5-fluorouracil and streptozotocin in advanced colorectal cancer. J Clin Oncol. 1984; 2:770-773. View in: Pubmed

      • Immunological and cytogenetic studies in two cases of B-cell acute lymphoblastic leukemia (Burkitt's type). Cancer Genet Cytogenet. 1983 Oct; 10(2):167-75. View in: Pubmed

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      • Chemotherapy for acute myelogenous leukemia in children and adults: VAPA update. Blood. 1983 Aug; 62(2):315-9. View in: Pubmed

      • Long-term hepatic arterial infusion of 5-fluorodeoxyuridine for liver metastases using an implantable infusion pump. J Clin Oncol. 1983 May; 1(5):337-44. View in: Pubmed

      • Acute leukemia after radiotherapy in a patient with Turcot's syndrome. Impaired colony formation in skin fibroblast cultures after irradiation. Am J Med. 1983 Feb; 74(2):343-8. View in: Pubmed

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      Dana-Farber Cancer Institute

      450 Brookline Avenue Dana 1602 Boston, MA 02215
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      Dana-Farber Cancer Institute

      Location Avtar

      Dana-Farber Cancer Institute

      450 Brookline Avenue Dana 1602 Boston, MA 02215
      Get Direction
      42.3374, -71.1082

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      Robert J. Mayer, MD

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