The Claudia Adams Barr Program in Innovative Basic Cancer Research at Dana-Farber Cancer Institute is widely recognized as one of the largest and most successful programs of its kind. Based on a rigorous and highly selective process, the program selects the brightest, most creative scientists and funds their most innovative ideas to propel basic research discoveries that transform cancer treatment. Claudia Adams Barr Program investigators have made tremendous advances and spearheaded breakthroughs that are improving care, quality of life, and survival for patients everywhere.