SAN ANTONIO - Myles Brown, MD today received the 2019 AACR Distinguished Lectureship in Breast Cancer Research award. Brown accepted the award at the 42nd annual San Antonio Breast Cancer Symposium where he delivered a lecture on “Essential genes and cistromes in breast cancer.”
Brown, the Emil Frei III Professor of Medicine at Dana-Farber Cancer Institute and Harvard Medical School, was recognized for his pioneering research involving steroid receptor-coregulators that has put a spotlight on the dynamic ability of these proteins to regulate the genome. Notably, his research has elucidated the epigenetic factors underlying the action of steroid hormones and effectively shaped the current understanding of the role of nuclear hormone receptors in normal physiology and breast cancer.
Celina Kleer, MD was the recipient of the 2019 AACR Outstanding Investigator Award for Breast Cancer Research.
“These researchers have made real progress in understanding mechanisms of breast cancer progression which has informed novel therapies against this disease. They truly deserve these awards for their efforts in helping countless patients with breast cancer,” said SABCS Codirector Carlos Arteaga, MD, ex-officio member of both award selection committees, Past President of the AACR, and director of the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern. “The hard work and dedication of Drs. Brown and Kleer have helped to shape our fundamental understanding of the complex interactions of hormones and proteins in breast cancer. Their lectures are among the many reasons why SABCS continues to be a leading global voice in breast cancer research.”
Brown obtained his undergraduate degree in biology from Yale University and his M.D. from the Johns Hopkins University School of Medicine. He completed training in internal medicine at Brigham and Women's Hospital while doing research with David Livingston, MD, at Dana-Farber. He went on to training in medical oncology at Dana-Farber and postdoctoral research with Phillip Sharp at MIT, and joined the faculty of the Dana-Farber and HMS. From 2002 to 2010, he served as chief of the Division of Molecular and Cellular Oncology at Dana-Farber. In 2010, together with Shirley Liu, PhD, he founded the Center for Functional Cancer Epigenetics at Dana-Farber.