About the Center for Personal Cancer Vaccines (CPCV)
Welcome to Dana-Farber Cancer Institute's Center for Personal Cancer Vaccines (CPCV). Our interdisciplinary team of physicians, scientists, and staff is dedicated to the development of therapeutic vaccines tailored specifically to each patient's individual cancer through clinical trials and correlative research.
In recent years, members of our Center, directed by Patrick Ott, MD, PhD, have conducted collaborative, investigator-initiated studies in patients with solid tumors that have demonstrated proof of concept data supporting the potential of personalized cancer vaccines (Ott and Hu Nature 2017; Keskin and Anandappa Nature 2019).
A key feature of our Center is strong clinical trial design, along with expertise in fundamental cancer immunology and developing cutting edge technologies (see our Dana-Farber/Harvard Medical School collaborators at the Translational Immunogenomics Lab (TIGL)). Our interdisciplinary team is well positioned to remain at the forefront of personalized cancer immunotherapy.