Childhood Neuroblastoma Program

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Childhood Cancer Clinical Trials

Find answers to common questions about clinical trials for childhood cancer, including whether or not a clinical trial may be the right choice for your child. Contact us and we can help you navigate your options.

Clinical Trials for Pediatric Patients

About the Childhood Neuroblastoma Program

Neuroblastoma is a cancerous tumor that forms in the nerve tissue of infants and young children. It typically begins in the abdomen; however, it can also develop in the neck, chest, and pelvis.

Our doctors utilize the latest therapies for pediatric neuroblastoma treatment, including MIBG therapy at Dana-Farber/Boston Children's Cancer and Blood Disorders Center. Your child's care team will work together to determine the best treatment options for your child's individual needs.

We diagnose and treat children with neuroblastoma, including relapsed and refractory neuroblastoma, at the Childhood Solid Tumor Center.

How We Diagnose and Treat Childhood Neuroblastoma

If your child's doctor suspects neuroblastoma, they will perform several diagnostic tests to confirm an accurate diagnosis. These tests may include sophisticated imaging studies, bone marrow aspiration, biopsies, and blood and urine tests.

After diagnosis, your child's team of cancer specialists will recommend a personalized treatment plan. Neuroblastoma treatment will depend on your child's age; the tumor's location, size, shape, and stage; and whether the cancer has spread.

Treatment may include surgery to remove the tumor, followed by radiation therapy and chemotherapy.

We also use innovative approaches such as targeted therapy, high-dose chemotherapy, and metaiodobenzylguanidine (MIBG) therapy. MIBG therapy is a leading-edge approach that helps deliver targeted radiation therapy with fewer side effects.

After treatment, we continue to monitor and evaluate your child's health with regular check-ups. We also provide emotional health and well-being support through our pediatric survivorship programs.

Childhood Neuroblastoma Clinical Trials and Research

Research is a top priority at Dana-Farber/Boston Children's, and our physicians work continuously to translate laboratory findings into clinical therapies. We offer newly diagnosed patients and children with relapsed neuroblastoma access to clinical trials.

Our Childhood Neuroblastoma Program Specialists

When your child is in the care of our specialists, they will have an expert team on their side.

Our pediatric neuroblastoma care team includes:

  • Oncologists
  • Surgeons
  • Hematology nurses
  • Oncology nurse practitioners
  • Imaging specialists
  • Pathologists
  • Stem cell transplantation specialists
  • Support staff including psychiatrists, psychologists, child life specialists, social workers, nutritionists, and school specialists

See our entire Childhood Solid Tumor Treatment Team.