Coronavirus (COVID-19) information for Dana-Farber patients & families Learn more
Please note that some translations using Google Translate may not be accurately represented and downloaded documents cannot be translated. Dana-Farber assumes no liability for inaccuracies that may result from using this third-party tool, which is for website translation and not clinical interactions. You may request a live medical interpreter for a discussion about your care.
Leiomyosarcoma is a very rare, but very treatable cancer. It is a type of soft tissue sarcoma that grows in muscle tissue. In children, it usually grows in the gastrointestinal tract, which includes the stomach, small intestines, colon, appendix, rectum
and anus. It can be difficult to detect because the tumor may be covered by other structures, such as skeletal muscle.
Dana-Farber/Boston Children’s Cancer and Blood Disorders Center provides comprehensive medical and surgical care for children with childhood leiomyosarcoma in our Bone and Soft Tissue Tumors Program.
Types of childhood leiomyosarcoma include:
The exact cause of childhood leiomyosarcoma is not entirely understood, but studies suggest that genetics may play a role in the formation of all soft tissue sarcomas. In addition:
Because soft tissue sarcomas affect tissue that is elastic and easily moved, a tumor may exist for a long time before being discovered, growing large and pushing aside surrounding tissue. Symptoms vary greatly with the size, location, and spread of the
tumor, but may include:
Surgery to remove the tumor is the primary treatment for childhood leiomyosarcoma, sometimes followed by chemotherapy and radiation therapy to destroy any cancer cells that may have spread beyond the tumor, and to prevent a recurrence.
Please refer to childhood soft tissue sarcomas for additional information about diagnosis, treatment, and care that your child will receive from our experienced clinicians.
New Patient Appointments
Find answers to common questions about clinical trials for
childhood cancer, including whether or not a clinical trial may be the right
choice for your child. You can also email your questions to firstname.lastname@example.org