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What is Diffuse Intrinsic Pontine Glioma (DIPG)?

  • Diffuse intrinsic pontine gliomas (DIPG) are highly aggressive and difficult to treat brain tumors found at the base of the brain. They are glial tumors, meaning they arise in the brain's glial tissues — tissues made up of cells that help support and protect the brain's neurons. These tumors are found in an area of the brainstem (the lowest, stem-like part of the brain) called the pons, which controls many of the body's most vital functions such as breathing, blood pressure, and heart rate.

    Approximately 300 children are diagnosed with diffuse intrinsic pontine glioma (DIPG) each year, usually between the ages of 5 and 9. Although the prognosis for DIPG remains very poor, new research led by Dana-Farber/Boston Children's may provide the key to improved treatment options.

    DIPG Treatment at Dana-Farber/Boston Children's

    Children and adolescents with diffuse intrinsic pontine gliomas (DIPG) are treated at Dana-Farber/Boston Children's through our Glioma Program, one of the world's largest pediatric glioma treatment programs. Our brain tumor specialists have extensive expertise in treating all types of gliomas, including DIPGs.

    Learn more

    Find more in-depth information on diffuse intrinsic pontine gliomas on the Dana-Farber/Boston Children's website, including answers to:

    • How is diffuse intrinsic pontine glioma diagnosed?
    • What is the best treatment for DIPG?
    • What is the latest research on DIPG?
    • What is the long-term outlook for children with DIPG?