Matthew Freedman, MD

Matthew Freedman, MD

Contact Information

Office Phone Number

617-582-8598

On This Page

Researcher

Physician

Professor of Medicine, Harvard Medical School
David Goldstein Chair, Dana-Farber Cancer Institute

Publications

    • Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription. Res Sq. 2024 Feb 02. View in: Pubmed

    • Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer. bioRxiv. 2024 Jan 12. View in: Pubmed

    • The PENGUIN approach to reconstruct protein interactions at enhancer-promoter regions and its application to prostate cancer. Nat Commun. 2023 Dec 06; 14(1):8084. View in: Pubmed

    • Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping. Nat Med. 2023 Dec 04. View in: Pubmed

    • Liquid biopsy epigenomic profiling for cancer subtyping. Nat Med. 2023 Nov; 29(11):2737-2741. View in: Pubmed

    • Author Correction: A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus. Nat Commun. 2023 Oct 19; 14(1):6623. View in: Pubmed

    • A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus. Nat Commun. 2023 08 23; 14(1):5118. View in: Pubmed

    • Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor-driven Programs. Eur Urol. 2023 11; 84(5):455-460. View in: Pubmed

    • Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development. bioRxiv. 2023 Apr 12. View in: Pubmed

    • Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer. Nat Cancer. 2023 05; 4(5):699-715. View in: Pubmed

    • Analysis of evolutionary dynamics and clonal architecture in prostate cancer. bioRxiv. 2023 Mar 25. View in: Pubmed

    • Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes. Cancer Discov. 2023 03 01; 13(3):632-653. View in: Pubmed

    • Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients. medRxiv. 2023 Feb 24. View in: Pubmed

    • Optimized high-throughput screening of non-coding variants identified from genome-wide association studies. Nucleic Acids Res. 2023 02 22; 51(3):e18. View in: Pubmed

    • Epigenomic charting and functional annotation of risk loci in renal cell carcinoma. Nat Commun. 2023 01 21; 14(1):346. View in: Pubmed

    • IL7 genetic variation and toxicity to immune checkpoint blockade in patients with melanoma. Nat Med. 2022 12; 28(12):2592-2600. View in: Pubmed

    • Germline variants associated with toxicity to immune checkpoint blockade. Nat Med. 2022 12; 28(12):2584-2591. View in: Pubmed

    • Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential. Nat Commun. 2022 11 30; 13(1):7367. View in: Pubmed

    • Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci. J Natl Cancer Inst. 2022 11 14; 114(11):1533-1544. View in: Pubmed

    • A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer. Cancer Res. 2022 10 17; 82(20):3673-3686. View in: Pubmed

    • Patterns of structural variation define prostate cancer across disease states. JCI Insight. 2022 09 08; 7(17). View in: Pubmed

    • Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation. Nat Genet. 2022 09; 54(9):1364-1375. View in: Pubmed

    • Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence. Cancer Discov. 2022 09 02; 12(9):2074-2097. View in: Pubmed

    • The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response. Cancer Res. 2022 08 16; 82(16):2848-2859. View in: Pubmed

    • Addition of Germline Testing to Tumor-Only Sequencing Improves Detection of Pathogenic Germline Variants in Men With Advanced Prostate Cancer. JCO Precis Oncol. 2022 Aug; 6:e2200329. View in: Pubmed

    • Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome. JCI Insight. 2022 05 23; 7(10). View in: Pubmed

    • MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets. Nat Commun. 2022 05 13; 13(1):2559. View in: Pubmed

    • CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies. Elife. 2022 05 12; 11. View in: Pubmed

    • Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer. Clin Epigenetics. 2022 05 04; 14(1):60. View in: Pubmed

    • ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer. Nat Commun. 2022 04 27; 13(1):2282. View in: Pubmed

    • HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer. Nat Genet. 2022 05; 54(5):670-683. View in: Pubmed

    • A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes. Cell Rep Med. 2022 03 15; 3(3):100542. View in: Pubmed

    • Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis. Clin Cancer Res. 2022 Mar 01; 28(5):928-938. View in: Pubmed

    • A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer. Cell Rep. 2022 02 22; 38(8):110417. View in: Pubmed

    • Androgen receptor and MYC equilibration centralizes on developmental super-enhancer. Nat Commun. 2021 12 15; 12(1):7308. View in: Pubmed

    • Predicting master transcription factors from pan-cancer expression data. Sci Adv. 2021 Nov 26; 7(48):eabf6123. View in: Pubmed

    • H3K27ac HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility. Am J Hum Genet. 2021 12 02; 108(12):2284-2300. View in: Pubmed

    • Allele-specific epigenetic activity in prostate cancer and normal prostate tissue implicates prostate cancer risk mechanisms. Am J Hum Genet. 2021 11 04; 108(11):2071-2085. View in: Pubmed

    • Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer. Nat Commun. 2021 10 01; 12(1):5775. View in: Pubmed

    • Exonic variants undergoing allele-specific selection in cancers. BMC Med Genomics. 2021 05 31; 14(1):142. View in: Pubmed

    • Clinical Utility of Cell-free and Circulating Tumor DNA in Kidney and Bladder Cancer: A Critical Review of Current Literature. Eur Urol Oncol. 2021 12; 4(6):893-903. View in: Pubmed

    • A polymorphism in the promoter of FRAS1 is a candidate SNP associated with metastatic prostate cancer. Prostate. 2021 07; 81(10):683-693. View in: Pubmed

    • Impact of Pathogenic Germline DNA Damage Repair alterations on Response to Intense Neoadjuvant Androgen Deprivation Therapy in High-risk Localized Prostate Cancer. Eur Urol. 2021 09; 80(3):295-303. View in: Pubmed

    • Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer. Nat Commun. 2021 03 30; 12(1):1979. View in: Pubmed

    • Trans-ethnic variation in germline variants of patients with renal cell carcinoma. Cell Rep. 2021 03 30; 34(13):108926. View in: Pubmed

    • EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer. Nat Cancer. 2021 04; 2(4):444-456. View in: Pubmed

    • Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases. Mol Oncol. 2021 07; 15(7):1942-1955. View in: Pubmed

    • Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma. Nat Commun. 2021 02 05; 12(1):808. View in: Pubmed

    • CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity. Nat Cancer. 2021 01; 2(1):34-48. View in: Pubmed

    • Author Correction: Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nat Med. 2020 Oct; 26(10):1663. View in: Pubmed

    • Ovarian Cancer Risk Variants Are Enriched in Histotype-Specific Enhancers and Disrupt Transcription Factor Binding Sites. Am J Hum Genet. 2020 10 01; 107(4):622-635. View in: Pubmed

    • Prostate cancer reactivates developmental epigenomic programs during metastatic progression. Nat Genet. 2020 08; 52(8):790-799. View in: Pubmed

    • A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer. Nat Commun. 2020 07 17; 11(1):3598. View in: Pubmed

    • Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nat Med. 2020 07; 26(7):1041-1043. View in: Pubmed

    • Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019. J Clin Oncol. 2020 08 20; 38(24):2798-2811. View in: Pubmed

    • Plasma cell-free DNA variant analysis compared with methylated DNA analysis in renal cell carcinoma. Genet Med. 2020 08; 22(8):1366-1373. View in: Pubmed

    • Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer. Nat Commun. 2020 04 24; 11(1):2020. View in: Pubmed

    • Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors. Cancer Immunol Res. 2020 08; 8(8):1075-1084. View in: Pubmed

    • Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer. Oncotarget. 2020 Apr 14; 11(15):1321-1333. View in: Pubmed

    • Correction: Evaluation of significant genome-wide association studies risk-SNPs in young breast cancer patients. PLoS One. 2020; 15(3):e0230529. View in: Pubmed

    • Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations. Clin Cancer Res. 2020 06 01; 26(11):2673-2680. View in: Pubmed

    • Allele-Specific QTL Fine Mapping with PLASMA. Am J Hum Genet. 2020 02 06; 106(2):170-187. View in: Pubmed

    • A Study of High-Grade Serous Ovarian Cancer Origins Implicates the SOX18 Transcription Factor in Tumor Development. Cell Rep. 2019 12 10; 29(11):3726-3735.e4. View in: Pubmed

    • CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer. Cell Rep. 2019 11 19; 29(8):2355-2370.e6. View in: Pubmed

    • Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness. Cancer Res. 2020 02 01; 80(3):624-638. View in: Pubmed

    • Genome-wide germline correlates of the epigenetic landscape of prostate cancer. Nat Med. 2019 10; 25(10):1615-1626. View in: Pubmed

    • CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation. Cancer Discov. 2019 11; 9(11):1538-1555. View in: Pubmed

    • Sex specific associations in genome wide association analysis of renal cell carcinoma. Eur J Hum Genet. 2019 10; 27(10):1589-1598. View in: Pubmed

    • Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer. iScience. 2019 Jul 26; 17:242-255. View in: Pubmed

    • Evaluation of significant genome-wide association studies risk - SNPs in young breast cancer patients. PLoS One. 2019; 14(5):e0216997. View in: Pubmed

    • Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants. Cancer Res. 2019 07 01; 79(13):3192-3204. View in: Pubmed

    • A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants. Nat Genet. 2019 05; 51(5):815-823. View in: Pubmed

    • A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2). Clin Cancer Res. 2019 07 15; 25(14):4480-4492. View in: Pubmed

    • Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women. Gynecol Oncol. 2019 05; 153(2):343-355. View in: Pubmed

    • Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions. Nat Commun. 2019 01 08; 10(1):171. View in: Pubmed

    • The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study. PLoS Med. 2019 01; 16(1):e1002724. View in: Pubmed

    • Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia. Cancer Cell. 2018 12 10; 34(6):982-995.e7. View in: Pubmed

    • Large-scale transcriptome-wide association study identifies new prostate cancer risk regions. Nat Commun. 2018 10 04; 9(1):4079. View in: Pubmed

    • Precision Prevention and Early Detection of Cancer: Fundamental Principles. Cancer Discov. 2018 07; 8(7):803-811. View in: Pubmed

    • A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer. Cell. 2018 07 12; 174(2):422-432.e13. View in: Pubmed

    • Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants. Nat Commun. 2018 06 11; 9(1):2256. View in: Pubmed

    • Corrigendum re "Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma" [Eur Urol 2017;72:747-54]. Eur Urol. 2018 09; 74(3):e85-e86. View in: Pubmed

    • Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017. J Clin Oncol. 2018 02 01; 36(4):414-424. View in: Pubmed

    • Cross-Cancer Analysis Reveals Novel Pleiotropic Associations-Response. Cancer Res. 2017 11 01; 77(21):6045-6046. View in: Pubmed

    • Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer. Elife. 2017 09 11; 6. View in: Pubmed

    • Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma. Eur Urol. 2017 11; 72(5):747-754. View in: Pubmed

    • The association between germline BRCA2 variants and sensitivity to platinum-based chemotherapy among men with metastatic prostate cancer. Cancer. 2017 Sep 15; 123(18):3532-3539. View in: Pubmed

    • Genome-wide association study identifies multiple risk loci for renal cell carcinoma. Nat Commun. 2017 06 09; 8:15724. View in: Pubmed

    • ASPirin Intervention for the REDuction of colorectal cancer risk (ASPIRED): a study protocol for a randomized controlled trial. Trials. 2017 02 01; 18(1):50. View in: Pubmed

    • Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci. Br J Cancer. 2017 Feb 14; 116(4):524-535. View in: Pubmed

    • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. Nat Commun. 2016 09 07; 7:12675. View in: Pubmed

    • Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors. JCI Insight. 2016 Aug 18; 1(13). View in: Pubmed

    • Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer. Nat Genet. 2016 10; 48(10):1142-50. View in: Pubmed

    • Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. Cancer Discov. 2016 09; 6(9):1052-67. View in: Pubmed

    • Pharmacogenomic Markers of Targeted Therapy Toxicity in Patients with Metastatic Renal Cell Carcinoma. Eur Urol Focus. 2016 Dec 15; 2(6):633-639. View in: Pubmed

    • Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. Cancer Res. 2016 09 01; 76(17):5103-14. View in: Pubmed

    • Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nat Commun. 2016 Apr 07; 7:10979. View in: Pubmed

    • Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia. Blood. 2016 05 26; 127(21):2598-606. View in: Pubmed

    • A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men. EBioMedicine. 2015 Dec; 2(12):1957-64. View in: Pubmed

    • Validation and genomic interrogation of the MET variant rs11762213 as a predictor of adverse outcomes in clear cell renal cell carcinoma. Cancer. 2016 Feb 01; 122(3):402-10. View in: Pubmed

    • The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis. Nat Genet. 2015 Nov; 47(11):1346-51. View in: Pubmed

    • Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer. Carcinogenesis. 2015 Nov; 36(11):1341-53. View in: Pubmed

    • CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants. Nat Med. 2015 Nov; 21(11):1357-63. View in: Pubmed

    • Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer. Nat Commun. 2015 Sep 22; 6:8234. View in: Pubmed

    • Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2015 Oct; 24(10):1574-84. View in: Pubmed

    • Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions. Hum Mol Genet. 2015 Oct 01; 24(19):5603-18. View in: Pubmed

    • Inference of transcriptional regulation in cancers. Proc Natl Acad Sci U S A. 2015 Jun 23; 112(25):7731-6. View in: Pubmed

    • A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. Cancer Discov. 2015 Aug; 5(8):878-91. View in: Pubmed

    • Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci. Hum Mol Genet. 2015 Jul 01; 24(13):3595-607. View in: Pubmed

    • Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases. Hum Genet. 2015 Apr; 134(4):439-50. View in: Pubmed

    • Identification of six new susceptibility loci for invasive epithelial ovarian cancer. Nat Genet. 2015 Feb; 47(2):164-71. View in: Pubmed

    • Association of prostate cancer risk variants with gene expression in normal and tumor tissue. Cancer Epidemiol Biomarkers Prev. 2015 Jan; 24(1):255-60. View in: Pubmed

    • A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nat Genet. 2014 Oct; 46(10):1103-9. View in: Pubmed

    • Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types. Hum Mol Genet. 2014 Oct 01; 23(19):5294-302. View in: Pubmed

    • Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations. J Natl Cancer Inst. 2013 Dec 18; 105(24):1852-61. View in: Pubmed

    • Lessons from postgenome-wide association studies: functional analysis of cancer predisposition loci. J Intern Med. 2013 Nov; 274(5):414-24. View in: Pubmed

    • Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4. Am J Hum Genet. 2013 Nov 07; 93(5):906-14. View in: Pubmed

    • Deconvoluting complex tissues for expression quantitative trait locus-based analyses. Philos Trans R Soc Lond B Biol Sci. 2013; 368(1620):20120363. View in: Pubmed

    • Clinical uncertainty of prostate cancer genetic risk panels. Sci Transl Med. 2013 Apr 24; 5(182):182ed6. View in: Pubmed

    • Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metab. 2013 Mar 05; 17(3):343-52. View in: Pubmed

    • Integrative eQTL-based analyses reveal the biology of breast cancer risk loci. Cell. 2013 Jan 31; 152(3):633-41. View in: Pubmed

    • Single nucleotide polymorphisms and risk of recurrence of renal-cell carcinoma: a cohort study. Lancet Oncol. 2013 Jan; 14(1):81-7. View in: Pubmed

    • Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11252-7. View in: Pubmed

    • Calling amplified haplotypes in next generation tumor sequence data. Genome Res. 2012 Feb; 22(2):362-74. View in: Pubmed

    • The genetics of cancer risk. Cancer J. 2011 Nov-Dec; 17(6):416-22. View in: Pubmed

    • The impact of common genetic variations in genes of the sex hormone metabolic pathways on steroid hormone levels and prostate cancer aggressiveness. Cancer Prev Res (Phila). 2011 Dec; 4(12):2044-50. View in: Pubmed

    • Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14902-7. View in: Pubmed

    • Principles for the post-GWAS functional characterization of cancer risk loci. Nat Genet. 2011 Jun; 43(6):513-8. View in: Pubmed

    • SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer. J Clin Oncol. 2011 Jun 20; 29(18):2565-73. View in: Pubmed

    • Do genetic polymorphisms predict risk of recurrence in patients with localized renal cell carcinoma? Results from a cohort study. J Clin Oncol. 2011 May 20; 29(15_suppl):4506. View in: Pubmed

    • National Cancer Institute Prostate Cancer Genetics Workshop. Cancer Res. 2011 May 15; 71(10):3442-6. View in: Pubmed

    • mRNA expression signature of Gleason grade predicts lethal prostate cancer. J Clin Oncol. 2011 Jun 10; 29(17):2391-6. View in: Pubmed

    • Association of prostate cancer risk Loci with disease aggressiveness and prostate cancer-specific mortality. Cancer Prev Res (Phila). 2011 May; 4(5):719-28. View in: Pubmed

    • Normal-pressure hydrocephalus: is there a genetic predisposition? Can J Neurol Sci. 2011 Mar; 38(2):274-81. View in: Pubmed

    • Inherited variants in the chemokine CCL2 gene and prostate cancer aggressiveness in a Caucasian cohort. Clin Cancer Res. 2011 Mar 15; 17(6):1546-52. View in: Pubmed

    • Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis. PLoS Genet. 2010 Nov 11; 6(11):e1001204. View in: Pubmed

    • Genetics of prostate cancer risk. Mt Sinai J Med. 2010 Nov-Dec; 77(6):643-54. View in: Pubmed

    • Genome-wide association study of prostate cancer mortality. Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11):2869-76. View in: Pubmed

    • Single-nucleotide polymorphisms in p53 pathway and aggressiveness of prostate cancer in a Caucasian population. Clin Cancer Res. 2010 Nov 01; 16(21):5244-51. View in: Pubmed

    • Allelic selection of amplicons in glioblastoma revealed by combining somatic and germline analysis. PLoS Genet. 2010 Sep 02; 6(9):e1001086. View in: Pubmed

    • Prevalence of primitive reflexes and Parkinsonian signs in dementia. Can J Neurol Sci. 2010 Sep; 37(5):601-7. View in: Pubmed

    • Fatty acid synthase polymorphisms, tumor expression, body mass index, prostate cancer risk, and survival. J Clin Oncol. 2010 Sep 01; 28(25):3958-64. View in: Pubmed

    • Inherited variations in AR, ESR1, and ESR2 genes are not associated with prostate cancer aggressiveness or with efficacy of androgen deprivation therapy. Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1871-8. View in: Pubmed

    • A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. J Clin Endocrinol Metab. 2010 Sep; 95(9):E121-7. View in: Pubmed

    • Chromosome 8q24-Associated Cancers and MYC. Genes Cancer. 2010 Jun; 1(6):555-9. View in: Pubmed

    • A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians. Hum Mol Genet. 2010 Aug 01; 19(15):3089-101. View in: Pubmed

    • 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9742-6. View in: Pubmed

    • A systematic approach to understand the functional consequences of non-protein coding risk regions. Cell Cycle. 2010 Jan 15; 9(2):256-9. View in: Pubmed

    • Prostate cancer risk allele specific for African descent associates with pathologic stage at prostatectomy. Cancer Epidemiol Biomarkers Prev. 2010 Jan; 19(1):1-8. View in: Pubmed

    • Power to detect selective allelic amplification in genome-wide scans of tumor data. Bioinformatics. 2010 Feb 15; 26(4):518-28. View in: Pubmed

    • STrengthening the REporting of Genetic Association Studies (STREGA)--an extension of the STROBE statement. Genet Epidemiol. 2009 Nov; 33(7):581-98. View in: Pubmed

    • An admixture scan in 1,484 African American women with breast cancer. Cancer Epidemiol Biomarkers Prev. 2009 Nov; 18(11):3110-7. View in: Pubmed

    • Prevalence and functional analysis of sequence variants in the ATR checkpoint mediator Claspin. Mol Cancer Res. 2009 Sep; 7(9):1510-6. View in: Pubmed

    • Replication of prostate cancer risk loci in a Japanese case-control association study. J Natl Cancer Inst. 2009 Oct 07; 101(19):1330-6. View in: Pubmed

    • Functional enhancers at the gene-poor 8q24 cancer-linked locus. PLoS Genet. 2009 Aug; 5(8):e1000597. View in: Pubmed

    • The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet. 2009 Aug; 41(8):882-4. View in: Pubmed

    • Evaluation of the 8q24 prostate cancer risk locus and MYC expression. Cancer Res. 2009 Jul 01; 69(13):5568-74. View in: Pubmed

    • Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X. PLoS Genet. 2009 May; 5(5):e1000490. View in: Pubmed

    • Nanodelivery of MRI contrast agent enhances sensitivity of detection of lung cancer metastases. Acad Radiol. 2009 May; 16(5):627-37. View in: Pubmed

    • Evaluation of 8q24 and 17q risk loci and prostate cancer mortality. Clin Cancer Res. 2009 May 01; 15(9):3223-30. View in: Pubmed

    • STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement. Eur J Clin Invest. 2009 Apr; 39(4):247-66. View in: Pubmed

    • Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. J Clin Epidemiol. 2009 Jun; 62(6):597-608.e4. View in: Pubmed

    • Prostate cancer disparities in Black men of African descent: a comparative literature review of prostate cancer burden among Black men in the United States, Caribbean, United Kingdom, and West Africa. Infect Agent Cancer. 2009 Feb 10; 4 Suppl 1:S2. View in: Pubmed

    • Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement. Eur J Epidemiol. 2009; 24(1):37-55. View in: Pubmed

    • STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement. PLoS Med. 2009 Feb 03; 6(2):e22. View in: Pubmed

    • STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement. Ann Intern Med. 2009 Feb 03; 150(3):206-15. View in: Pubmed

    • Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement. Hum Genet. 2009 Mar; 125(2):131-51. View in: Pubmed

    • Prostate cancer cognitive-behavioral factors in a West African population. J Immigr Minor Health. 2009 Aug; 11(4):258-67. View in: Pubmed

    • Quantitative gene expression at the 8q24 prostate cancer risk locus. J Clin Oncol. 2008 May 20; 26(15_suppl):5055. View in: Pubmed

    • Inherited variation in the androgen pathway is associated with the efficacy of androgen-deprivation therapy in men with prostate cancer. J Clin Oncol. 2008 Feb 20; 26(6):842-7. View in: Pubmed

    • Circulating colony stimulating factor-1 and breast cancer risk. Cancer Res. 2008 Jan 01; 68(1):18-21. View in: Pubmed

    • Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts. Int J Cancer. 2007 Dec 15; 121(12):2661-7. View in: Pubmed

    • Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations. Hum Mol Genet. 2008 Mar 15; 17(6):825-34. View in: Pubmed

    • Sequence variants of Estrogen receptor (beta) and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Biomarkers Prev. 2007; 10:1973-81. View in: Pubmed

    • Sequence variants of estrogen receptor beta and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):1973-81. View in: Pubmed

    • Genetic determinants of circulating insulin-like growth factor (IGF)-I, IGF binding protein (BP)-1, and IGFBP-3 levels in a multiethnic population. J Clin Endocrinol Metab. 2007 Sep; 92(9):3660-6. View in: Pubmed

    • Genetic determinants of prostate cancer risk. BJU Int. 2007 Aug; 100(2):241-3. View in: Pubmed

    • A common 8q24 variant in prostate and breast cancer from a large nested case-control study. Cancer Res. 2007 Apr 01; 67(7):2951-6. View in: Pubmed

    • Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet. 2007 May; 39(5):638-44. View in: Pubmed

    • Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study. Breast Cancer Res. 2007; 9(1):R18. View in: Pubmed

    • Transferability of tag SNPs in genetic association studies in multiple populations. Nat Genet. 2006 Nov; 38(11):1298-303. View in: Pubmed

    • Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort. Cancer Epidemiol Biomarkers Prev. 2006 Oct; 15(10):1993-7. View in: Pubmed

    • Abnormalities on chest radiograph reported in subjects in a cancer screening trial. Chest. 2006 Sep; 130(3):688-93. View in: Pubmed

    • Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men. Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38):14068-73. View in: Pubmed

    • Reader variability: what we can learn from computer-aided detection experiments. J Am Coll Radiol. 2006 Jun; 3(6):446-55. View in: Pubmed

    • Common genetic variation at PTEN and risk of sporadic breast and prostate cancer. Cancer Epidemiol Biomarkers Prev. 2006 May; 15(5):1021-5. View in: Pubmed

    • Haplotype analysis of the HSD17B1 gene and risk of breast cancer: a comprehensive approach to multicenter analyses of prospective cohort studies. Cancer Res. 2006 Feb 15; 66(4):2468-75. View in: Pubmed

    • Common genetic variation in IGF1 and prostate cancer risk in the Multiethnic Cohort. J Natl Cancer Inst. 2006 Jan 18; 98(2):123-34. View in: Pubmed

    • A tumor-targeted nanodelivery system to improve early MRI detection of cancer. Mol Imaging. 2006 Jan-Mar; 5(1):41-52. View in: Pubmed

    • IGF-1 genetic variation and breast cancer risk: the multi-ethnic cohort. Cancer Epidemiol Biomarkers Prev. 2006; 15:172-4. View in: Pubmed

    • Haplotype-based association studies of IGFBPI and IGFBP3 with prostate and Breast Cancer Risk: The multiethnic cohort. Cancer Epidemiology Biomarkers and Prevention. 2006; 15:1993-07. View in: Pubmed

    • Igf-I genetic variation and breast cancer: the multiethnic cohort. Cancer Epidemiol Biomarkers Prev. 2006 Jan; 15(1):172-4. View in: Pubmed

    • A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3). Breast Cancer Res. 2006; 8(5):R54. View in: Pubmed

    • A candidate gene approach to searching for low-penetrance breast and prostate cancer genes. Nat Rev Cancer. 2005 12; 5(12):977-85. View in: Pubmed

    • Genetic variation in the HSD17B1 gene and risk of prostate cancer. PLoS Genet. 2005 Nov; 1(5):e68. View in: Pubmed

    • Long-term transfusion of polymerized bovine hemoglobin in a Jehovah's Witness following chemotherapy for myeloid leukemia: a case report. Transfusion. 2005 Nov; 45(11):1735-8. View in: Pubmed

    • A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proc Natl Acad Sci U S A. 2005 Sep 13; 102(37):13194-9. View in: Pubmed

    • Reflectance confocal microscopy for characterization of mammary ductal structures and development of neoplasia in genetically engineered mouse models of breast cancer. J Biomed Opt. 2005 Sep-Oct; 10(5):051602. View in: Pubmed

    • A haplotype-based case-control study of BRCA1 and sporadic breast cancer risk. Cancer Res. 2005 Aug 15; 65(16):7516-22. View in: Pubmed

    • Demonstrating stratification in a European American population. Nat Genet. 2005 Aug; 37(8):868-72. View in: Pubmed

    • The behavioural neurology assessment. Can J Neurol Sci. 2005 May; 32(2):167-77. View in: Pubmed

    • Como international conference position statement: lung cancer screening for early diagnosis 5 years after the 1998 Varese conference. Chest. 2005 Apr; 127(4):1146-51. View in: Pubmed

    • Common genetic variation in the sex steroid hormone-binding globulin (SHBG) gene and circulating shbg levels among postmenopausal women: the Multiethnic Cohort. J Clin Endocrinol Metab. 2005 Apr; 90(4):2198-204. View in: Pubmed

    • Final results of the Lung Screening Study, a randomized feasibility study of spiral CT versus chest X-ray screening for lung cancer. Lung Cancer. 2005 Jan; 47(1):9-15. View in: Pubmed

    • Diagnostic procedures after a positive spiral computed tomography lung carcinoma screen. Cancer. 2005 Jan 01; 103(1):157-63. View in: Pubmed

    • A pilot study to establish a clinical model to perform phase II studies of breast cancer chemopreventive agents in women at high risk with biomarkers as surrogate endpoints for activity. Clin Cancer Res. 2004 Dec 15; 10(24):8332-40. View in: Pubmed

    • Systematic evaluation of genetic variation at the androgen receptor locus and risk of prostate cancer in a multiethnic cohort study. Am J Hum Genet. 2005 Jan; 76(1):82-90. View in: Pubmed

    • Common variation in BRCA2 and breast cancer risk: a haplotype-based analysis in the Multiethnic Cohort. Hum Mol Genet. 2004 Oct 15; 13(20):2431-41. View in: Pubmed

    • Computer-aided detection of Severe Acute Respiratory Syndrome (SARS) on chest radiography. Int Congr Ser. 2004 Jun; 1268:908-910. View in: Pubmed

    • Improved small volume lung cancer detection with computer-aided detection: database characteristics and imaging of response to breast cancer risk reduction strategies. Ann N Y Acad Sci. 2004 May; 1020:175-89. View in: Pubmed

    • Assessing the impact of population stratification on genetic association studies. Nat Genet. 2004 Apr; 36(4):388-93. View in: Pubmed

    • Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patients. Breast Cancer Res Treat. 2004 Mar; 84(2):99-105. View in: Pubmed

    • Sensitivity of noncommercial computer-aided detection system for mammographic breast cancer detection: pilot clinical trial. Radiology. 2004 Apr; 231(1):208-14. View in: Pubmed

    • State-of-the-art screening for lung cancer (part 1): the chest radiograph. Thorac Surg Clin. 2004 Feb; 14(1):43-52. View in: Pubmed

    • Acceptability of diagnostic tests for breast cancer. Breast Cancer Res Treat. 2003 May; 79(2):199-206. View in: Pubmed

    • Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals. Hum Hered. 2003; 55(4):179-90. View in: Pubmed

    • Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. Circulation. 2001 Nov 27; 104(22):2641-4. View in: Pubmed

    • Frontal lobe functions. Curr Neurol Neurosci Rep. 2001 Nov; 1(6):547-52. View in: Pubmed

    • Genetic susceptibility to MS: a second stage analysis in Canadian MS families. Neurogenetics. 2001 Jul; 3(3):145-51. View in: Pubmed

    • Popular diets: correlation to health, nutrition, and obesity. J Am Diet Assoc. 2001 Apr; 101(4):411-20. View in: Pubmed

    • Relationship of psychosis to aggression, apathy and function in dementia. Int J Geriatr Psychiatry. 2001 Feb; 16(2):123-30. View in: Pubmed

    • Establishment of a cytokine-producing anaplastic large-cell lymphoma cell line containing the t(2;5) translocation: potential role of cytokines in clinical manifestations. Leuk Lymphoma. 2001 Feb; 40(5-6):599-611. View in: Pubmed

    • Recombinant human granulocyte colony-stimulating factor therapy for patients with neutropenia and/or neutrophil dysfunction secondary to glycogen storage disease type 1b. Blood. 2001 Jan 15; 97(2):376-82. View in: Pubmed

    • Digitized mammography: a clinical trial of postmenopausal women randomly assigned to receive raloxifene, estrogen, or placebo. J Natl Cancer Inst. 2001 Jan 03; 93(1):51-6. View in: Pubmed

    • Vitamin B12 deficiency and incontinence in older people. Can J Urol. 2000 Aug; 7(4):1077-80. View in: Pubmed

    • Matched unrelated bone marrow transplantation for combined immunodeficiency. Bone Marrow Transplant. 2000 Mar; 25(6):613-21. View in: Pubmed

    • Stem cell transplantation in patients with severe congenital neutropenia without evidence of leukemic transformation. Blood. 2000 Feb 15; 95(4):1195-8. View in: Pubmed

    • Final report of the technical requirements for image-guided spine procedures Workshop, April 17-20, 1999, Ellicott City, Maryland, USA. Comput Aided Surg. 2000; 5(3):180-215. View in: Pubmed

    • Shwachman syndrome: phenotypic manifestations of sibling sets and isolated cases in a large patient cohort are similar. J Pediatr. 1999 Jul; 135(1):81-8. View in: Pubmed

    • Telomere shortening in leucocyte subsets of long-term survivors of allogeneic bone marrow transplantation. Br J Haematol. 1999 Jun; 105(4):997-1001. View in: Pubmed

    • Serendipity in diagnostic imaging: magnetic resonance imaging of the breast. J Natl Cancer Inst. 1998 Dec 02; 90(23):1792-800. View in: Pubmed

    • Age-related changes in D2 receptor binding with iodine-123-iodobenzofuran SPECT. J Nucl Med. 1998 Sep; 39(9):1511-8. View in: Pubmed

    • Quantitative neuronal c-fos and c-jun expression in Alzheimer's disease. Neurobiol Aging. 1998 Sep-Oct; 19(5):393-400. View in: Pubmed

    • Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE. Neurosci Lett. 1998 Jul 10; 250(3):189-92. View in: Pubmed

    • L-deprenyl in Alzheimer's disease: cognitive and behavioral effects. Neurology. 1998 Mar; 50(3):660-8. View in: Pubmed

    • Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease. Exp Neurol. 1998 Mar; 150(1):40-4. View in: Pubmed

    • Orbitofrontal function, object alternation and perseveration. Cereb Cortex. 1998 Jan-Feb; 8(1):18-27. View in: Pubmed

    • Building communities that promote successful aging. West J Med. 1997 Oct; 167(4):216-9. View in: Pubmed

    • Decreased brain glucose metabolism in microvessels from patients with Alzheimer's disease. Ann N Y Acad Sci. 1997 Sep 26; 826:248-53. View in: Pubmed

    • Polycythemia secondary to focal nodular hyperplasia. J Pediatr Surg. 1997 Sep; 32(9):1386-7. View in: Pubmed

    • Mutations in the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia. Leukemia. 1997 Jan; 11(1):120-5. View in: Pubmed

    • A full genome search in multiple sclerosis. Nat Genet. 1996 Aug; 13(4):472-6. View in: Pubmed

    • Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis. J Exp Med. 1996 May 01; 183(5):2109-17. View in: Pubmed

    • Normal aging and patterns of hematologic disease. Compr Ther. 1996 May; 22(5):304-10. View in: Pubmed

    • Usefulness of follow-up regional cerebral blood flow measurements by single-photon emission computed tomography in the differential diagnosis of dementia. J Neuroimaging. 1996 Jan; 6(1):23-8. View in: Pubmed

    • Monosomy 7 and activating RAS mutations accompany malignant transformation in patients with congenital neutropenia. Blood. 1995 Dec 15; 86(12):4579-86. View in: Pubmed

    • Failure to detect missense mutations in the S182 gene in a series of late-onset Alzheimer's disease cases. Neurosci Lett. 1995 Dec 08; 201(2):188-90. View in: Pubmed

    • Autocrine feedback death and regulation of mature T lymphocyte antigen responses. Int Rev Immunology. 1995; 13:115-34. View in: Pubmed

    • Autocrine feedback death and the regulation of mature T lymphocyte antigen responses. Int Rev Immunol. 1995; 13(2):115-34. View in: Pubmed

    • Are the associations between Alzheimer's disease and polymorphisms in the apolipoprotein E and the apolipoprotein CII genes due to linkage disequilibrium? Ann Neurol. 1994 Jul; 36(1):97-100. View in: Pubmed

    • DNA sequences in the promoter region of the NF1 gene are highly conserved between human and mouse. Genomics. 1994 Jun; 21(3):649-52. View in: Pubmed

    • SPECT for differential diagnosis of dementia and correlation of rCBF with cognitive impairment. Can J Neurol Sci. 1994 May; 21(2):104-11. View in: Pubmed

    • Alteration of irradiated shuttle vector processing by exposure of human lymphoblast host cells to single or split gamma-ray doses. Int J Radiat Biol. 1994 Feb; 65(2):157-64. View in: Pubmed

    • Immunological tolerance by antigen-induced apoptosis of mature T lymphocytes. Adv Exp Med Biol. 1994; 365:81-9. View in: Pubmed

    • The CA repeat marker D17S791 is located within 40 kb of the WNT3 gene on chromosome 17q. Genomics. 1993 Dec; 18(3):728-9. View in: Pubmed

    • Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia. Science. 1993 Aug 20; 261(5124):1041-4. View in: Pubmed

    • Identification of yeast artificial chromosomes containing the inversion 16 p-arm breakpoint associated with acute myelomonocytic leukemia. Blood. 1993 Aug 01; 82(3):716-21. View in: Pubmed

    • Mutations caused by gamma-radiation-induced double-strand breaks in a shuttle plasmid replicated in human lymphoblasts. Int J Radiat Biol. 1992 Nov; 62(5):555-62. View in: Pubmed

    • Mutation spectrum in gamma-irradiated shuttle vector replicated in ataxia-telangiectasia lymphoblasts. Radiat Res. 1992 Jun; 130(3):331-9. View in: Pubmed

    • Selective delayed alternation deficits in dominantly inherited olivopontocerebellar atrophy. Brain Cogn. 1991 Jul; 16(2):121-9. View in: Pubmed

    • Differential diagnosis and management of chronic cough. Compr Ther. 1990 Oct; 16(10):46-53. View in: Pubmed

    • Hodgkin's disease in children: treatment with MOPP and low-dose, extended field irradiation without laparotomy. Late results and toxicity. Med Pediatr Oncol. 1990; 18(4):265-72. View in: Pubmed

    • Office-based evaluation of renal function in elderly patients receiving nonsteroidal anti-inflammatory drugs. J Am Board Fam Pract. 1988 Apr-Jun; 1(2):77-80. View in: Pubmed

    • Common hematologic problems: diagnosis and treatment. Geriatrics. 1983 Apr; 38(4):119-23, 127-30, 134. View in: Pubmed

    • Pneumococcal bacteremia in adults: age-dependent differences in presentation and in outcome. J Am Geriatr Soc. 1983 Jan; 31(1):19-27. View in: Pubmed

    • Hodgkin's disease in children: treatment with low dose radiation and MOPP without staging laparotomy: a preliminary report. Cancer. 1979 Jul; 44(1):80-6. View in: Pubmed

    • Genetic alterations of Streptococcus mutans' virulence. Adv Exp Med Biol. 1978; 107:661-72. View in: Pubmed

    • Presence of a nonsplenic platelet pool. Blood. 1977 Sep; 50(3):419-25. View in: Pubmed

    • Ribonuclease activity in renal failure: evidence for toxicity. Proc Eur Dial Transplant Assoc. 1977; 14:528-34. View in: Pubmed

    • Benzene and lead inhibition of rabbit reticulocyte heme and protein synthesis: evidence for additive toxicity of these two components of commercial gasoline. Res Commun Chem Pathol Pharmacol. 1976 Mar; 13(3):473-88. View in: Pubmed

    • Hemin reversal of benzene-induced inhibition of reticulocyte protein synthesis. Blood. 1976 Jan; 47(1):145-54. View in: Pubmed

    • Elevated platelet count and megathrombocyte number in sickle cell anemia. Blood. 1975 Oct; 46(4):579-82. View in: Pubmed

    • Invited review. Thalassemia: an abnormality in globin chain synthesis. Am J Med Sci. 1974 May; 267(5):256-65. View in: Pubmed

    • Structure of the large -chain polyribosome of rabbit reticulocytes rendered isoleucine-deficient by O-methylthreonine. Mol Pharmacol. 1971 May; 7(3):317-22. View in: Pubmed

    • Translational control in hemoglobin syntheskis. Cold Spring Harb Symp Quant Biol. 1969; 34:567-78. View in: Pubmed

    • The characterization of separated alpha and beta-chain polyribosomes in rabbit reticulocytes. J Biol Chem. 1968 Dec 25; 243(24):6446-50. View in: Pubmed

    • Response to psychologic stress in persons who are potentially hypertensive. Circulation. 1953 Jun; 7(6):874-9. View in: Pubmed