
Nancy U. Lin, MD
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Biography
Nancy U. Lin, MD
Dr. Lin received her bachelors degrees from Stanford University, followed by an MD from Harvard Medical School. She completed her residency in internal medicine at Brigham and Women's Hospital and went on to complete fellowships in medical oncology and hematology at Dana-Farber Cancer Institute. Since 2005, she has been a member of the faculty in the Department of Medical Oncology at Dana-Farber Cancer Institute.
Dr. Lin serves as associate chief of the Division of Breast Oncology at Dana-Farber. She is the founder and director of the Metastatic Breast Cancer Program and the Program for Patients with Breast Cancer Brain Metastases. She is internationally recognized for her expertise in the care of patients with all stages of breast cancer. A Professor of Medicine at Harvard Medical School, Dr. Lin’s research focuses on developing more effective therapies for patients with metastatic breast cancer, including patients with brain metastases or leptomeningeal disease (cancer that has spread to the brain or spinal fluid). She has led multiple clinical trials which have led to new treatment options for patients with metastatic breast cancer. Dr. Lin is also an active translational science researcher, and directs the Breast Oncology Cohorts and Biorepository Program at Dana-Farber. She is a multi-PI of the NCI SPORE grant in Breast Cancer at Dana-Farber/Harvard Cancer Center. Her research has been supported by the National Cancer Institute, Department of Defense, Breast Cancer Research Foundation, Conquer Cancer, Susan G. Komen, and V Foundation.
Dr. Lin is a current Komen scholar, and the recipient of the George Canellos Award for Excellence in Clinical Investigation and Clinical Care, a Team Science Award from Dana-Farber Cancer Institute, and the Distinguished Researcher Award from the Massachusetts Society of Clinical Oncologists.
Researcher
Physician
Centers/Programs
Clinical Interests
Brain and leptomeningeal metastases, HER2+ breast cancer, Metastatic breast cancer
Diseases Treated
Board Certification
- Hematology, 2005
- Internal Medicine, 2002
- Medical Oncology, 2015
Fellowship
- Dana-Farber/Partners CancerCare, Hematology/Oncology
Residency
- Brigham and Women's Hospital, Internal Medicine
Medical School
- Harvard Medical School
Recent Awards
- George Canellos Award for Excellence in Clinical Investigation and Clinical Care, 2011
- University of Padua Award for Advances in Breast Cancer, 2016
- Team Science Award, Dana-Farber Cancer Institute, 2019
- Distinguished Researcher Award, Massachusetts Society of Clinical Oncologists, 2023
Research
In recent years, treatments for people with breast cancer have dramatically improved. This has led to higher cure rates for patients with early-stage breast cancer, and longer survival in patients with metastatic breast cancer. However, there is still much progress left to be made. Dr. Lin’s research focuses on closing the gaps in breast cancer treatments, specifically, 1) Developing new therapies for patients with metastatic breast cancer, 2) Finding effective therapies for patients whose cancer has spread to the brain or spinal fluid, 3) Understanding why cancers become resistant to certain treatments and how to overcome that resistance, 4) Working together with laboratory-based researchers to identify new technologies and new treatments to prioritize for clinical trials. Dr. Lin has led or been integrally involved in clinical trials that have resulted in new treatment options for patients with metastatic breast cancer, including those with brain metastases, such as trastuzumab deruxtecan (TDXd, Enhertu), tucatinib, neratinib, and trastuzumab-emtansine (T-DM1, Kadcyla) based combinations. As a multi-Principal Investigator of the Dana-Farber/Harvard Cancer Center SPORE grant in breast cancer, she works to pull together clinical researchers and lab-based researchers to work collaboratively on high-impact projects to advance our understanding of breast cancer and develop clinical trials that come out of cutting-edge science. Dr. Lin mentors numerous trainees and early career faculty on a range of research projects, from research into blood-based tests such as circulating tumor DNA, to “big data” project involving real world data, to potentially paradigm-changing projects in HER2-positive metastatic breast cancer and ER-positive metastatic breast cancer. Finally, she directs the EMBRACE metastatic breast cancer program, which includes a robust clinical program to support patients in specialized testing, clinical trial matching, and patient education, as well as a research arm, with the goal to learn from our patients and their unique experiences.
Publications
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Analysis of HER2 expression changes from breast primary to brain metastases and the impact of HER2-low expression on overall survival. Neuro Oncol. 2025 Jan 12; 27(1):184-194. View in: Pubmed
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Destructive and protective effects and therapeutic targets of IL-36 family cytokines in dry eye disease. Ocul Surf. 2025 Jan 10; 36:83-93. View in: Pubmed
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Central Nervous System Metastases in Breast Cancer. Curr Treat Options Oncol. 2025 Jan; 26(1):14-35. View in: Pubmed
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Enhancing the Predictive Utility of MHR for Senile Osteoporosis: Unaddressed Considerations and Future Directions [Response to Letter]. Clin Interv Aging. 2024; 19:2165-2166. View in: Pubmed
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Windfarm construction alters soil multinutrient cycling by destabilizing microfauna community in a mountain ecosystem. J Environ Manage. 2025 Jan; 373:123758. View in: Pubmed
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Molecular Genetic and Clinical Characteristics of Fetuses With Chromosome 16 Short-Arm Microdeletions/Microduplications. J Clin Lab Anal. 2024 Dec; 38(24):e25132. View in: Pubmed
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Race and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Positive Breast Cancer in the Randomized RxPONDER Trial. J Natl Cancer Inst. 2024 Dec 05. View in: Pubmed
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Derivation and external validation of prediction model for hypertensive disorders of pregnancy in twin pregnancies: a retrospective cohort study in southeastern China. BMJ Open. 2024 Dec 03; 14(12):e083654. View in: Pubmed
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Cannabidiol for Scan-Related Anxiety in Women With Advanced Breast Cancer: A Randomized Clinical Trial. JAMA Netw Open. 2024 Dec 02; 7(12):e2450391. View in: Pubmed
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Incidence, treatment patterns, and mortality for patients with breast cancer during the first year of the COVID-19 pandemic: a population-based study. Breast Cancer Res Treat. 2024 Dec 02. View in: Pubmed
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Publisher Correction: Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial. Nat Med. 2024 Dec; 30(12):3780. View in: Pubmed
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Correction: Patient-Reported Outcomes 10 Years After Breast-Conserving Surgery for Early-Stage Breast Cancer. Ann Surg Oncol. 2024 Dec; 31(13):8933. View in: Pubmed
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Integrated proteomic and metabolomic analysis reveals the potential therapeutic mechanism of Quanduzhong capsule in rats with spontaneous hypertension and knee osteoarthritis. J Ethnopharmacol. 2025 Jan 31; 340:119176. View in: Pubmed
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Dual impacts of serine/glycine-free diet in enhancing antitumor immunity and promoting evasion via PD-L1 lactylation. Cell Metab. 2024 Dec 03; 36(12):2493-2510.e9. View in: Pubmed
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Role of antibody drug conjugates in the treatment of patients with breast cancer brain metastases. Ther Adv Med Oncol. 2024; 16:17588359241292266. View in: Pubmed
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Prenatal diagnosis of fetal skeletal anomalies via whole-exome sequencing in a tertiary referral center. Sci Rep. 2024 11 09; 14(1):27371. View in: Pubmed
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The Monocyte-to-High-Density Lipoprotein Cholesterol Ratio as a Novel Predictor of the Prevalence of Senile Osteoporosis. Clin Interv Aging. 2024; 19:1773-1788. View in: Pubmed
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A Phase II Study of Atezolizumab, Pertuzumab, and High-Dose Trastuzumab for Central Nervous System Metastases in Patients with HER2-Positive Breast Cancer. Clin Cancer Res. 2024 Nov 01; 30(21):4856-4865. View in: Pubmed
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A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features. Nat Med. 2024 Nov; 30(11):3236-3249. View in: Pubmed
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Osteopontin is a therapeutic target that drives breast cancer recurrence. Nat Commun. 2024 Oct 24; 15(1):9174. View in: Pubmed
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Patient-reported outcomes, and perceptions and knowledge about recurrence in women with hormone receptor-positive breast cancer. Breast Cancer Res Treat. 2025 Feb; 209(3):513-520. View in: Pubmed
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Integrative Multiomic Profiling of Triple-Negative Breast Cancer for Identifying Suitable Therapies. Clin Cancer Res. 2024 Oct 15; 30(20):4768-4779. View in: Pubmed
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Intracranial outcomes following neurosurgical resection in patients with brain metastases secondary to HER2-positive breast cancer versus other subtypes. Breast Cancer Res Treat. 2025 Jan; 209(2):303-314. View in: Pubmed
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Single Nucleotide Polymorphism array analysis for fetuses from balanced translocation carriers at the second trimester. Heliyon. 2024 Oct 30; 10(20):e38387. View in: Pubmed
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Concordance of PD-L1 Expression in Metastatic Triple-negative Breast Cancer Between the 22C3 and E1L3N Antibodies Using Combined Positive Scoring. Appl Immunohistochem Mol Morphol. 2024 Oct 01; 32(9):417-424. View in: Pubmed
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Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial. Nat Med. 2024 Dec; 30(12):3717-3727. View in: Pubmed
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A pathology foundation model for cancer diagnosis and prognosis prediction. Nature. 2024 Oct; 634(8035):970-978. View in: Pubmed
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Patient-Reported Outcomes 10 Years After Breast-Conserving Surgery for Early-Stage Breast Cancer. Ann Surg Oncol. 2024 Oct; 31(10):6831-6840. View in: Pubmed
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A randomized phase III double-blind placebo-controlled trial of first-line chemotherapy and trastuzumab with or without bevacizumab for patients with HER2/neu-positive metastatic breast cancer: a trial of the ECOG-ACRIN Cancer Research Group (E1105). Breast Cancer Res Treat. 2024 Sep; 207(2):275-282. View in: Pubmed
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Large-size PVG-based waveguide simulation and uniformity optimization for AR-HUD. Opt Express. 2024 Jul 01; 32(14):25362-25374. View in: Pubmed
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Pure estrogen receptor antagonists potentiate capecitabine activity in ESR1-mutant breast cancer. NPJ Breast Cancer. 2024 Jun 08; 10(1):42. View in: Pubmed
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Clinicogenomic characterization of inflammatory breast cancer. bioRxiv. 2024 May 10. View in: Pubmed
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Abnormal vascular structure and function within brain metastases is linked to pembrolizumab resistance. Neuro Oncol. 2024 05 03; 26(5):965-974. View in: Pubmed
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HER2/ERBB2 copy number analysis by targeted next-generation sequencing in breast cancer. Am J Clin Pathol. 2024 May 02; 161(5):436-442. View in: Pubmed
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A randomized phase III double-blind placebo-controlled trial of first line chemotherapy and trastuzumab with or without bevacizumab for patients with HER2/neu-positive metastatic breast cancer: a trial of the ECOG-ACRIN Cancer Research Group (E1105). Res Sq. 2024 Apr 29. View in: Pubmed
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Clinicopathological characteristics and eligibility for adjuvant olaparib of germline BRCA1/2 mutation carriers with HER2-negative early breast cancer. NPJ Breast Cancer. 2024 Apr 16; 10(1):28. View in: Pubmed
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Prognosis and treatment outcomes for patients with stage IA triple-negative breast cancer. NPJ Breast Cancer. 2024 Apr 04; 10(1):26. View in: Pubmed
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Mortality Risks Over 20 Years in Men With Stage I to III Hormone Receptor-Positive Breast Cancer. JAMA Oncol. 2024 Apr 01; 10(4):508-515. View in: Pubmed
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From Serendipity to Intention: Development of Brain-Penetrant PARP1-Selective Inhibitors. Clin Cancer Res. 2024 Apr 01; 30(7):1217-1219. View in: Pubmed
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ASO Visual Abstract: Long-Term Patient-Reported Arm Symptoms in Breast Cancer Survivors. Ann Surg Oncol. 2024 Apr; 31(4):2280-2281. View in: Pubmed
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Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial. Nat Commun. 2024 Mar 19; 15(1):2446. View in: Pubmed
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Survival analysis of patients with brain metastases at initial breast cancer diagnosis over the last decade. Breast Cancer Res Treat. 2024 Jun; 205(3):579-587. View in: Pubmed
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Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping. Nat Med. 2024 Mar; 30(3):907. View in: Pubmed
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Evolution of HER2 expression between pre-treatment biopsy and residual disease after neoadjuvant therapy for breast cancer. Eur J Cancer. 2024 Apr; 201:113920. View in: Pubmed
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Ectoine, from a Natural Bacteria Protectant to a New Treatment of Dry Eye Disease. Pharmaceutics. 2024 Feb 05; 16(2). View in: Pubmed
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Identification of key factors affecting neonicotinoid residues in crops and risk of dietary exposure. Environ Pollut. 2024 Mar 15; 345:123489. View in: Pubmed
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Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City. Nature. 2024 Feb; 626(8001):E18. View in: Pubmed
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Exploring the life experiences of school-aged children afflicted by tethered spinal cord syndrome: An interpretative qualitative study. Health Expect. 2024 02; 27(1):e13969. View in: Pubmed
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Impact of personalized diabetes care on distress and treatment satisfaction in people with breast cancer. Diabet Med. 2024 Apr; 41(4):e15292. View in: Pubmed
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Genetic testing for fetal loss of heterozygosity using single nucleotide polymorphism array and whole-exome sequencing. Sci Rep. 2024 01 25; 14(1):2190. View in: Pubmed
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First Report of Filipino ß0-Thalassemia/ß-Thalassemia in a Chinese Family. Hemoglobin. 2024 Jan; 48(1):34-38. View in: Pubmed
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Experience of copy number variation sequencing applied in spontaneous abortion. BMC Med Genomics. 2024 01 08; 17(1):15. View in: Pubmed
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Prevalence, Dynamics, and Prognostic Role of Clonal Hematopoiesis of Indeterminate Potential in Patients With Breast Cancer. J Clin Oncol. 2024 Nov; 42(31):3666-3679. View in: Pubmed
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Intrauterine ultrasound phenotyping, molecular characteristics, and postnatal follow-up of fetuses with the 15q11.2 BP1-BP2 microdeletion syndrome: a single-center, retrospective clinical study. BMC Pregnancy Childbirth. 2024 Jan 03; 24(1):23. View in: Pubmed
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Peripheral blood circular RNA circ-0008102 may serve as a novel clinical biomarker in beta-thalassemia patients. Eur J Pediatr. 2024 Mar; 183(3):1367-1379. View in: Pubmed
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Qualification of a multiplexed tissue imaging assay and detection of novel patterns of HER2 heterogeneity in breast cancer. NPJ Breast Cancer. 2024 Jan 02; 10(1):2. View in: Pubmed
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Feasibility and Clinical Utility of Reporting Hereditary Cancer Predisposition Pathogenic Variants Identified in Research Germline Sequencing: A Prospective Interventional Study. JCO Precis Oncol. 2024 Jan; 8:e2300266. View in: Pubmed
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Impact of post-dilatation on post-procedural physiology, microcirculatory resistance, and target vessel failure in STEMI patients undergoing PPCI: A single-center experience. Int J Cardiol. 2024 Mar 15; 399:131685. View in: Pubmed
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Fetal congenital talipes equinovarus: genomic abnormalities and obstetric follow-up results. J Matern Fetal Neonatal Med. 2024 Dec; 37(1):2299113. View in: Pubmed
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Association between hepatitis B virus replication during pregnancy and perinatal outcomes: a retrospective cohort study. Ann Med. 2023; 55(2):2295396. View in: Pubmed
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Author Correction: Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer. Nat Commun. 2023 Dec 14; 14(1):8321. View in: Pubmed
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Long-Term Patient-Reported Arm Symptoms in Breast Cancer Survivors. Ann Surg Oncol. 2024 Mar; 31(3):1623-1633. View in: Pubmed
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Identification of a novel 91.5?kb-deletion (aa)FJ in the a-globin gene cluster using single-molecule real-time (SMRT) sequencing. J Matern Fetal Neonatal Med. 2023 Dec; 36(2):2254890. View in: Pubmed
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Peripheral blood TCR clonotype diversity as an age-associated marker of breast cancer progression. Proc Natl Acad Sci U S A. 2023 Dec 05; 120(49):e2316763120. View in: Pubmed
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Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer. Nat Commun. 2023 11 18; 14(1):7496. View in: Pubmed
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Development of a new 17-item Asthenopia Survey Questionnaire using Rasch analysis. Int J Ophthalmol. 2023; 16(11):1867-1875. View in: Pubmed
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Pertuzumab plus high-dose trastuzumab for HER2-positive breast cancer with brain metastases: PATRICIA final efficacy data. NPJ Breast Cancer. 2023 Nov 17; 9(1):94. View in: Pubmed
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Genetic evaluation for twin pregnancies using karyotyping and single nucleotide polymorphism array analysis. Gene. 2024 Feb 15; 895:148005. View in: Pubmed
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Prenatal diagnosis of fetal digestive system malformations and pregnancy outcomes at a tertiary referral center in Fujian, China: A retrospective study. Heliyon. 2023 Nov; 9(11):e21546. View in: Pubmed
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[Transcriptional regulation mechanism of differential accumulation of flavonoids in leaves and roots of Sarcandra glabra based on metabonomics and transcriptomics]. Zhongguo Zhong Yao Za Zhi. 2023 Nov; 48(21):5767-5778. View in: Pubmed
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Liquid biopsy epigenomic profiling for cancer subtyping. Nat Med. 2023 Nov; 29(11):2737-2741. View in: Pubmed
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Genetic analysis, ultrasound phenotype, and pregnancy outcomes of fetuses with Xp22.33 or Yp11.32 microdeletions. J Perinat Med. 2024 Jan 29; 52(1):96-101. View in: Pubmed
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Endoscopic ultrasound-guided injection of carbon nanoparticles suspension to label rectal cancer before neoadjuvant chemoradiotherapy: a retrospective cohort study. Gastroenterol Rep (Oxf). 2023; 11:goad062. View in: Pubmed
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Genotyping, sequencing and analysis of 140,000 adults from Mexico City. Nature. 2023 Oct; 622(7984):784-793. View in: Pubmed
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The Comparison of Two Whole-Genome Amplification Approaches for Noninvasive Preimplantation Genetic Testing (ni-PGT) and the Application Scenario of ni-PGT during the Fresh Cycle. J Mol Diagn. 2023 12; 25(12):945-956. View in: Pubmed
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Metrics of Anterior Sclera in Normal Chinese Adults: Anterior Segment Imaging Using the Swept-Source Optical Coherence Tomography. Eye Contact Lens. 2024 Jan 01; 50(1):23-28. View in: Pubmed
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Volatile Organic Compounds in Disposable Diapers and Baby Wipes in the US: A Survey of Products and Health Risks. Environ Sci Technol. 2023 09 19; 57(37):13732-13743. View in: Pubmed
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Structural and functional vascular dysfunction within brain metastases is linked to pembrolizumab inefficacy. bioRxiv. 2023 Aug 28. View in: Pubmed
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Disorders of the central nervous system: Insights from Notch and Nrf2 signaling. Biomed Pharmacother. 2023 Oct; 166:115383. View in: Pubmed
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Keeping It in the Family: HER3 as a Target in Brain Metastases. Clin Cancer Res. 2023 08 15; 29(16):2961-2963. View in: Pubmed
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Association of ambient PM10 and PM2.5 with coronary stenosis measured using selective coronary angiography. Ecotoxicol Environ Saf. 2023 Aug 07; 262:115338. View in: Pubmed
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Analysis of retest reliability for pregnant women undergoing cfDNA testing with a no-call result. Mol Biol Rep. 2023 Sep; 50(9):7649-7657. View in: Pubmed
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Carbendazim residue in plant-based foods in China: Consecutive surveys from 2011 to 2020. Environ Sci Ecotechnol. 2024 Jan; 17:100301. View in: Pubmed
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Adjuvant Olaparib for Germline BRCA Carriers With HER2-Negative Early Breast Cancer: Evidence and Controversies. Oncologist. 2023 07 05; 28(7):565-574. View in: Pubmed
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Pathogenic copy number variations are associated with foetal short femur length in a tertiary referral centre study. J Cell Mol Med. 2023 08; 27(16):2354-2361. View in: Pubmed
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Tucatinib Plus Trastuzumab and Capecitabine for ERBB2 (HER2)-Positive Metastatic Breast Cancer With Brain Metastases-Reply. JAMA Oncol. 2023 07 01; 9(7):1009. View in: Pubmed
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Non-invasive prenatal testing for the diagnosis of congenital abnormalities: Insights from a large multicenter study in southern China. Braz J Med Biol Res. 2023; 56:e12506. View in: Pubmed
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Regioselective stilbene O-methylations in Saccharinae grasses. Nat Commun. 2023 06 12; 14(1):3462. View in: Pubmed
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Pembrolizumab in brain metastases of diverse histologies: phase 2 trial results. Nat Med. 2023 07; 29(7):1728-1737. View in: Pubmed
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Clinical outcomes of de novo metastatic HER2-positive inflammatory breast cancer. NPJ Breast Cancer. 2023 Jun 02; 9(1):50. View in: Pubmed
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Estimating mortality in women with triple-negative breast cancer: The 'ESTIMATE triple-negative' tool. Eur J Cancer. 2023 08; 189:112930. View in: Pubmed
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Prenatal diagnosis of genetic aberrations in fetuses with pulmonary stenosis in southern China: a retrospective analysis. BMC Med Genomics. 2023 05 30; 16(1):119. View in: Pubmed
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Liquid biopsy for brain metastases and leptomeningeal disease in patients with breast cancer. NPJ Breast Cancer. 2023 May 24; 9(1):43. View in: Pubmed
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Classifying and evaluating fetuses with multicystic dysplastic kidney in etiologic studies. Exp Biol Med (Maywood). 2023 05; 248(10):858-865. View in: Pubmed
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Association between Overweight/Obesity and the Safety and Efficacy of COVID-19 Vaccination: A Systematic Review. Vaccines (Basel). 2023 May 17; 11(5). View in: Pubmed
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Identifying Patterns and Barriers in OncotypeDX Recurrence Score Testing in Older Patients With Early-Stage, Estrogen Receptor-Positive Breast Cancer: Implications for Guidance and Reimbursement. JCO Oncol Pract. 2023 08; 19(8):560-570. View in: Pubmed
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Prenatal diagnosis of non-mosaic sex chromosome abnormalities: a 10-year experience from a tertiary referral center. J Perinat Med. 2023 Sep 26; 51(7):904-912. View in: Pubmed
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Using single nucleotide polymorphism array for prenatal diagnosis in a large multicenter study in Southern China. Sci Rep. 2023 05 04; 13(1):7242. View in: Pubmed
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Incidence proportion and prognosis of leptomeningeal disease among patients with breast vs. non-breast primaries. Neuro Oncol. 2023 05 04; 25(5):973-983. View in: Pubmed
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Impact of Prior Authorization on Patient Access to Cancer Care. Am Soc Clin Oncol Educ Book. 2023 May; 43:e100036. View in: Pubmed
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Comprehensive research into prognostic and immune signatures of transcription factor family in breast cancer. BMC Med Genomics. 2023 04 25; 16(1):87. View in: Pubmed
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Understanding the activity of antibody-drug conjugates in primary and secondary brain tumours. Nat Rev Clin Oncol. 2023 06; 20(6):372-389. View in: Pubmed
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Determination of the effective dose of dexmedetomidine to achieve loss of consciousness during anesthesia induction. Front Med (Lausanne). 2023; 10:1158085. View in: Pubmed
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Genetic disorders and pregnancy outcomes of non-immune hydrops fetalis in a tertiary referral center. BMC Med Genomics. 2023 04 20; 16(1):83. View in: Pubmed
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Available Systemic Treatments and Emerging Therapies for Breast Cancer Brain Metastases. Curr Treat Options Oncol. 2023 06; 24(6):611-627. View in: Pubmed
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Survival in male breast cancer over the past 3 decades. J Natl Cancer Inst. 2023 04 11; 115(4):421-428. View in: Pubmed
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Insights into the Electron Transfer Behaviors of a Biocathode Regulated by Cathode Potentials in Microbial Electrosynthesis Cells for Biogas Upgrading. Environ Sci Technol. 2023 04 25; 57(16):6733-6742. View in: Pubmed
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Existential experiences and perceptions of death among children with terminal cancer: An interpretative qualitative study. Palliat Med. 2023 06; 37(6):866-874. View in: Pubmed
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Durable responses in patients with HER2+ breast cancer and leptomeningeal metastases treated with trastuzumab deruxtecan. NPJ Breast Cancer. 2023 Mar 30; 9(1):19. View in: Pubmed
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DISC1 as a prognostic biomarker correlated with immune infiltrates in gastric cancer. Heliyon. 2023 Apr; 9(4):e15058. View in: Pubmed
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Downregulation of Brassica napus MYB69 (BnMYB69) increases biomass growth and disease susceptibility via remodeling phytohormone, chlorophyll, shikimate and lignin levels. Front Plant Sci. 2023; 14:1157836. View in: Pubmed
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A phase I/II study of intrathecal trastuzumab in human epidermal growth factor receptor 2-positive (HER2-positive) cancer with leptomeningeal metastases: Safety, efficacy, and cerebrospinal fluid pharmacokinetics. Neuro Oncol. 2023 03 14; 25(3):557-565. View in: Pubmed
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The value of contrast-enhanced portal vein imaging at the hepatobiliary phase obtained with gadobenate dimeglumine for predicting decompensation and transplant-free survival in chronic liver disease. Eur Radiol. 2023 May; 33(5):3425-3434. View in: Pubmed
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Epidemiology, clinical outcomes, and unmet needs of patients with human epidermal growth factor receptor 2-positive breast cancer and brain metastases: A systematic literature review. Cancer Treat Rev. 2023 Apr; 115:102527. View in: Pubmed
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Time-trends in liver cancer incidence and mortality rates in the U.S. from 1975 to 2017: a study based on the Surveillance, Epidemiology, and End Results database. J Gastrointest Oncol. 2023 Feb 28; 14(1):312-324. View in: Pubmed
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Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial. Clin Cancer Res. 2023 02 16; 29(4):784-790. View in: Pubmed
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Polyphyllin VI screened from Chonglou by cell membrane immobilized chromatography relieves inflammatory pain by inhibiting inflammation and normalizing the expression of P2X3 purinoceptor. Front Pharmacol. 2023; 14:1117762. View in: Pubmed
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Tucatinib vs Placebo, Both in Combination With Trastuzumab and Capecitabine, for Previously Treated ERBB2 (HER2)-Positive Metastatic Breast Cancer in Patients With Brain Metastases: Updated Exploratory Analysis of the HER2CLIMB Randomized Clinical Trial. JAMA Oncol. 2023 02 01; 9(2):197-205. View in: Pubmed
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Multidisciplinary Management of Brain Metastasis from Breast Cancer. Hematol Oncol Clin North Am. 2023 02; 37(1):183-202. View in: Pubmed
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Clinicopathologic and sociodemographic factors associated with late relapse triple negative breast cancer in a multivariable logistic model: A multi-institution cohort study. Breast. 2023 Feb; 67:89-93. View in: Pubmed
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Application of the Single-Molecule Real-Time Technology (SMRT) for Identification of HKaa Thalassemia Allele. Lab Med. 2023 Jan 05; 54(1):65-71. View in: Pubmed
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Preclinical and Clinical Efficacy of Trastuzumab Deruxtecan in Breast Cancer Brain Metastases. Clin Cancer Res. 2023 01 04; 29(1):174-182. View in: Pubmed
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Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis. Nat Cancer. 2023 01; 4(1):128-147. View in: Pubmed
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Clinical findings and genetic analysis of patients with copy number variants involving 17p13.3 using a single nucleotide polymorphism array: a single-center experience. BMC Med Genomics. 2022 12 21; 15(1):268. View in: Pubmed
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Hoarding Disorder: The Current Evidence in Conceptualization, Intervention, and Evaluation. Psychiatr Clin North Am. 2023 03; 46(1):181-196. View in: Pubmed
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Factors Affecting Family Management Among Chinese Parents of Children With Leukemia: A Multisite Study. Cancer Nurs. 2023 Jul-Aug 01; 46(4):284-293. View in: Pubmed
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[Ultrasonographic phenotype and genetic analysis of fetuses with 17q12 microdeletion]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2022 Dec 10; 39(12):1329-1333. View in: Pubmed
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Central-positive complexes in ECT-induced seizures: Possible evidence for thalamocortical mechanisms. Clin Neurophysiol. 2023 Feb; 146:77-86. View in: Pubmed
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16p13.11 microdeletion/microduplication in fetuses: investigation of associated ultrasound phenotypes, genetic anomalies, and pregnancy outcome follow-up. BMC Pregnancy Childbirth. 2022 Dec 07; 22(1):913. View in: Pubmed
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Ultrasound-assisted carbon nanoparticle labeling of neoadjuvant chemotherapy for breast-conserving surgery in breast cancer. Quant Imaging Med Surg. 2023 Mar 01; 13(3):1825-1837. View in: Pubmed
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Retrospective analysis of the sex chromosomal copy number variations in 186 fetuses using single nucleotide polymorphism arrays. Front Genet. 2022; 13:997757. View in: Pubmed
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Subclavian brachial plexus metastasis from breast cancer: A case report. World J Clin Cases. 2022 Nov 26; 10(33):12261-12267. View in: Pubmed
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Retrospective analysis of genetic etiology and obstetric outcome of fetal cystic hygroma: A single-center study. Medicine (Baltimore). 2022 Nov 25; 101(47):e31689. View in: Pubmed
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Impact of COVID-19 pandemic on catheter ablation in China: A spatiotemporal analysis. Front Public Health. 2022; 10:1027926. View in: Pubmed
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PAHs bound to submicron particles in rural Chinese homes burning solid fuels. Ecotoxicol Environ Saf. 2022 Dec 01; 247:114274. View in: Pubmed
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Corrigendum: Chromosomal abnormalities and pregnancy outcomes for fetuses with gastrointestinal tract obstructions. Front Pediatr. 2022; 10:976997. View in: Pubmed
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Aumolertinib effectively reduces clinical symptoms of an EGFR L858R-mutant non-small cell lung cancer case coupled with osimertinib-induced severe thrombocytopenia: a case report. Anticancer Drugs. 2023 03 01; 34(3):455-459. View in: Pubmed
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HSP90 as a platform for the assembly of more effective cancer chemotherapy. Biochim Biophys Acta. 2012 Mar; 1823(3):756-66. View in: Pubmed
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High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer. Proc Natl Acad Sci U S A. 2011 Nov 08; 108(45):18378-83. View in: Pubmed
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Activation of Notch1 signaling by marrow-derived mesenchymal stem cells through cell-cell contact inhibits proliferation of hepatic stellate cells. Life Sci. 2011 Dec 19; 89(25-26):975-81. View in: Pubmed
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Salvage stereotactic radiosurgery for breast cancer brain metastases: outcomes and prognostic factors. Cancer. 2012 Apr 15; 118(8):2014-20. View in: Pubmed
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Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Genetics. 2011 Nov; 189(3):861-70. View in: Pubmed
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Shikani™ Seeing Optical Stylet-aided tracheal intubation in patients with a large epiglottic cyst. Chin Med J (Engl). 2011 Sep; 124(17):2795-8. View in: Pubmed
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Prevention of intraoperative awareness in a high-risk surgical population. N Engl J Med. 2011 Aug 18; 365(7):591-600. View in: Pubmed
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The ethical use of mandatory research biopsies. Nat Rev Clin Oncol. 2011 08 02; 8(10):620-5. View in: Pubmed
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Randomized phase II study of lapatinib plus capecitabine or lapatinib plus topotecan for patients with HER2-positive breast cancer brain metastases. J Neurooncol. 2011 Dec; 105(3):613-20. View in: Pubmed
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A phase II study of sagopilone (ZK 219477; ZK-EPO) in patients with breast cancer and brain metastases. Clin Breast Cancer. 2011 Dec; 11(6):376-83. View in: Pubmed
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Effect of very small tumor size on cancer-specific mortality in node-positive breast cancer. J Clin Oncol. 2011 Jul 01; 29(19):2619-27. View in: Pubmed
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Predictors of survival in patients with HER2+ metastatic breast cancer (MBC) treated with trastuzumab. J Clin Oncol. 2011 May 20; 29(15_suppl):e11100. View in: Pubmed
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TBCRC 018: Phase II study of iniparib plus chemotherapy to treat triple-negative breast cancer (TNBC) brain metastases (BM). J Clin Oncol. 2011 May 20; 29(15_suppl):TPS127. View in: Pubmed
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Efficacy and safety of retaspimycin hydrochloride (IPI-504) in combination with trastuzumab in patients (pts) with pretreated, locally advanced or metastatic HER2-positive breast cancer. J Clin Oncol. 2011 May 20; 29(15_suppl):590. View in: Pubmed
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HER2 suppression with the addition of lapatinib to trastuzumab in HER2-positive metastatic breast cancer (LPT112515). J Clin Oncol. 2011 May 20; 29(15_suppl):TPS113. View in: Pubmed
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Salvage stereotactic radiosurgery (SRS) after previous whole-brain radiation therapy (WBRT) for breast cancer brain metastases: Outcomes and prognostic factors including tumor phenotype. J Clin Oncol. 2011 May 20; 29(15_suppl):581. View in: Pubmed
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TBCRC 019: An open-label, randomized, phase II trial of nanoparticle albumin-bound paclitaxel with or without the anti-death receptor 5 (DR5) monoclonal antibody tigatuzumab in patients with metastatic, triple-negative (ER, PR, and HER2-negative) breast cancer. J Clin Oncol. 2011 May 20; 29(15_suppl):TPS128. View in: Pubmed
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Responses to subsequent anti-HER2 therapy after treatment with trastuzumab-DM1 in women with HER2-positive metastatic breast cancer. Ann Oncol. 2012 Jan; 23(1):93-97. View in: Pubmed
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Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases. Int J Radiat Oncol Biol Phys. 2012 Apr 01; 82(5):2111-7. View in: Pubmed
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Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nat Genet. 2011 Mar 06; 43(4):345-9. View in: Pubmed
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Troponin I and C-reactive protein are commonly detected in patients with breast cancer treated with dose-dense chemotherapy incorporating trastuzumab and lapatinib. Clin Cancer Res. 2011 May 15; 17(10):3490-9. View in: Pubmed
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EMBRACE, eribulin, and new realities of advanced breast cancer. Lancet. 2011 Mar 12; 377(9769):878-80. View in: Pubmed
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Chemotherapy agents in human epidermal growth factor receptor 2-positive breast cancer: time to step out of the limelight. J Clin Oncol. 2011 Jan 20; 29(3):251-3. View in: Pubmed
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[Anti-glioma effect of combination of bFGF-siRNA and Vpr in nude mice]. Zhonghua Zhong Liu Za Zhi. 2010 Oct; 32(10):725-8. View in: Pubmed
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Combined antitumor effect of Ad-bFGF-siRNA and Ad-Vpr on the growth of xenograft glioma in nude mouse model. Pathol Oncol Res. 2011 Jun; 17(2):237-42. View in: Pubmed
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Active immunization with glucose-dependent insulinotropic polypeptide vaccine influences brain function and behaviour in rats. Scand J Immunol. 2010 Jul; 72(1):1-7. View in: Pubmed
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Downregulation of N-cadherin expression inhibits invasiveness, arrests cell cycle and induces cell apoptosis in esophageal squamous cell carcinoma. Cancer Invest. 2010 Jun; 28(5):479-86. View in: Pubmed
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Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila. PLoS Genet. 2010 May 27; 6(5):e1000969. View in: Pubmed
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Dose-dense doxorubicin and cyclophosphamide followed by weekly paclitaxel with trastuzumab and lapatinib in HER2/neu-overexpressed/amplified breast cancer is not feasible because of excessive diarrhea. J Clin Oncol. 2010 Jun 20; 28(18):2982-8. View in: Pubmed
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Evidence for a novel blood RNA diagnostic for pediatric appendicitis: the riboleukogram. Pediatr Emerg Care. 2010 May; 26(5):333-8. View in: Pubmed
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Ethics of mandatory research biopsy for correlative end points within clinical trials in oncology. J Clin Oncol. 2010 May 20; 28(15):2635-40. View in: Pubmed
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Two-photon absorption circular dichroism: a new twist in nonlinear spectroscopy. Chemistry. 2010 Mar 15; 16(11):3504-9. View in: Pubmed
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The current status and the future of JAK2 inhibitors for the treatment of myeloproliferative diseases. Int J Hematol. 2010 Mar; 91(2):189-200. View in: Pubmed
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Adenovirus-mediated transfer of siRNA against basic fibroblast growth factor mRNA enhances the sensitivity of glioblastoma cells to chemotherapy. Med Oncol. 2011 Mar; 28(1):24-30. View in: Pubmed
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Adenovirus-mediated delivery of bFGF small interfering RNA increases levels of connexin 43 in the glioma cell line, U251. J Exp Clin Cancer Res. 2010 Jan 14; 29:3. View in: Pubmed
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Concordance of HER2 in primary tumor and leptomeningeal metastases: now what? Breast Cancer Res Treat. 2010 Aug; 123(1):129-31. View in: Pubmed
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Dose-dense adjuvant Doxorubicin and cyclophosphamide is not associated with frequent short-term changes in left ventricular ejection fraction. J Clin Oncol. 2009 Dec 20; 27(36):6117-23. View in: Pubmed
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[The effects of ginsenosides Rg3 on the expressions of VEGF and KDR in human lung squamous cancer cells]. Zhong Yao Cai. 2009 Nov; 32(11):1708-10. View in: Pubmed
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Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury. Ann Surg. 2009 Oct; 250(4):531-9. View in: Pubmed
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[Evaluation of retropalatal mechanical loads in patients with obstructive sleep apnea]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Oct; 44(10):819-24. View in: Pubmed
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Geographic distribution of lapatinib-induced skin rash: sparing of abdominal skin persists in the transverse rectus abdominis myocutaneous flap. J Clin Oncol. 2009 Dec 01; 27(34):e218-9. View in: Pubmed
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[Ginsenoside Rg3 induces apoptosis of human lung squamous cell carcinoma SK-MES-1 cell line]. Nan Fang Yi Ke Da Xue Xue Bao. 2009 Sep; 29(9):1823-6. View in: Pubmed
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Nonlinear development of shocklike structure in the solar wind. Phys Rev Lett. 2009 Jul 17; 103(3):031101. View in: Pubmed
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Use of BIBW 2992, a novel irreversible EGFR/HER2 tyrosine kinase inhibitor (TKI), to treat patients with HER2-positive metastatic breast cancer after failure of treatment with trastuzumab. J Clin Oncol. 2009 May 20; 27(15_suppl):1023. View in: Pubmed
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Clinicopathological features and sites of recurrence according to breast cancer subtype in the National Comprehensive Cancer Network (NCCN). J Clin Oncol. 2009 May 20; 27(15_suppl):543. View in: Pubmed
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Presentation of breast cancer in young women. J Clin Oncol. 2009 May 20; 27(15_suppl):6608. View in: Pubmed
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Sulforaphane down-regulates COX-2 expression by activating p38 and inhibiting NF-kappaB-DNA-binding activity in human bladder T24 cells. Int J Oncol. 2009 Apr; 34(4):1129-34. View in: Pubmed
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Multicenter phase II study of lapatinib in patients with brain metastases from HER2-positive breast cancer. Clin Cancer Res. 2009 Feb 15; 15(4):1452-9. View in: Pubmed
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N-cadherin knock-down decreases invasiveness of esophageal squamous cell carcinoma in vitro. World J Gastroenterol. 2009 Feb 14; 15(6):697-704. View in: Pubmed
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Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer: high incidence of central nervous system metastases. Cancer. 2008 Nov 15; 113(10):2638-45. View in: Pubmed
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Internal mammary nodes in breast cancer: diagnosis and implications for patient management -- a systematic review. J Clin Oncol. 2008 Oct 20; 26(30):4981-9. View in: Pubmed
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Preliminary safety results of dose-dense (dd) doxorubicin and cyclophosphamide (AC) followed by weekly paclitaxel (P) with trastuzumab (T) and lapatinib (L) in HER2 overexpressed/amplified breast cancer (BCA). J Clin Oncol. 2008 May 20; 26(15_suppl):518. View in: Pubmed
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A physician-reported neurological signs and symptoms worksheet (NSS WS) in EGF105084: A phase II study of lapatinib (lap) for pts with recurrent brain metastases (BM) from HER2+ breast cancer (BC). J Clin Oncol. 2008 May 20; 26(15_suppl):1078. View in: Pubmed
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Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol. 2008 Apr 20; 26(12):1993-9. View in: Pubmed
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Optimizing endocrine therapy for estrogen receptor-positive breast cancer: treating the right patients for the right length of time. J Clin Oncol. 2008 Apr 20; 26(12):1919-21. View in: Pubmed
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Advances in adjuvant endocrine therapy for postmenopausal women. J Clin Oncol. 2008 Feb 10; 26(5):798-805. View in: Pubmed
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Dose-escalation of filgrastim does not improve efficacy: clinical tolerability and long-term follow-up on CALGB study 9141 adjuvant chemotherapy for node-positive breast cancer patients using dose-intensified doxorubicin plus cyclophosphamide followed by paclitaxel. Cancer Treat Rev. 2008 May; 34(3):223-30. View in: Pubmed
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Treatment of HER2-positive breast cancer: new approaches, new opportunities. Breast Dis Quart. 2008; 18(4):336-338. View in: Pubmed
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Heterogeneity of breast cancer and implications of adjuvant chemotherapy. Breast Cancer. 2008; 15(1):31-4. View in: Pubmed
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Lapatinib and capecitabine for the treatment of brain metastases in patients with HER2+ breast cancer--an updated analysis from EGF105084. Breast Cancer Res Treat. 2007; 106(Suppl 1):Abstract 6076. View in: Pubmed
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AZD2171 for refractory breast cancer: a phase 2 trial. Breast Cancer Res Treat. 2007; 106(Suppl 1):Abstract 6080. View in: Pubmed
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Using pedometers to increase physical activity and improve health: a systematic review. JAMA. 2007 Nov 21; 298(19):2296-304. View in: Pubmed
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Blood vessel morphologic changes depicted with MR angiography during treatment of brain metastases: a feasibility study. Radiology. 2007 Dec; 245(3):824-30. View in: Pubmed
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Solitary electromagnetic pulses detected with super-Alfvénic flows in Earth's geomagnetic tail. Phys Rev Lett. 2007 Jun 29; 98(26):265001. View in: Pubmed
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EGF 105084, a phase II study of lapatinib for brain metastases in patients (pts) with HER2+ breast cancer following trastuzumab (T) based systemic therapy and cranial radiotherapy (RT). J Clin Oncol. 2007; 25(18S):abstract 1012. View in: Pubmed
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Optimal use of aromatase inhibitors: to lead or to follow? J Clin Oncol. 2007 Jul 01; 25(19):2639-41. View in: Pubmed
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Current status of thalassemia in minority populations in Guangxi, China. Clin Genet. 2007 May; 71(5):419-26. View in: Pubmed
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Brain metastases: the HER2 paradigm. Clin Cancer Res. 2007 Mar 15; 13(6):1648-55. View in: Pubmed
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Phase II study of CT-2103 as first- or second-line chemotherapy in patients with metastatic breast cancer: unexpected incidence of hypersensitivity reactions. Invest New Drugs. 2007 Aug; 25(4):369-75. View in: Pubmed
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Novel approaches to advanced breast cancer: bevacizumab and lapatinib. J Natl Compr Canc Netw. 2007 Mar; 5(3):314-23. View in: Pubmed
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HER2-positive breast cancer. J Clin Outcomes Management. 2007; 14(7):395-403. View in: Pubmed
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Anatomy versus biology: to what extent should estrogen receptor (ER) status influence the decision to recommend adjuvant chemotherapy?. Breast Dis Quart. 2007; 18(3):232-4. View in: Pubmed
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Phase II trial of lapatinib for brain metastases in patients with HER2+ breast cancer. J Clin Oncol. 2006 Jun 20; 24(18_suppl):503. View in: Pubmed
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Superiority of bi-dimensional measurements compared to RECIST in measuring response of metastatic brain tumors. J Clin Oncol. 2006; 24(18S):68s. View in: Pubmed
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[Effects of different treatment complex on esophageal vascular structures in patients with portal hypertension]. Zhonghua Wai Ke Za Zhi. 2006 Apr 01; 44(7):450-3. View in: Pubmed
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Dendritic plasticity of CA1 pyramidal neurons after transient global ischemia. Neuroscience. 2006 Jun 19; 140(1):191-201. View in: Pubmed
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[Clinical study on crossed disparity and uncrossed disparity in intermittent exotropia before and after surgery]. Zhonghua Yan Ke Za Zhi. 2006 Feb; 42(2):139-44. View in: Pubmed
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Evaluation of response to lapatinib in patients with HER2-positive metastatic breast cancer using FDG-PET. Breast Ca Res Treat. 2006; 100(Suppl 1):S67. View in: Pubmed
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Tumor therapeutic response and vessel tortuosity: preliminary report in metastatic breast cancer. Med Image Comput Comput Assist Interv. 2006; 9(Pt 2):561-8. View in: Pubmed
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Vitamin C inactivates the proteasome inhibitor PS-341 in human cancer cells. Clin Cancer Res. 2006 Jan 01; 12(1):273-80. View in: Pubmed
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Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: results from CALGB 9342. Breast Cancer Res. 2006; 8(6):R66. View in: Pubmed
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Dose density in breast cancer: a simple message? J Natl Cancer Inst. 2005 Dec 07; 97(23):1712-4. View in: Pubmed
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[Research actuality and expectation on embryo toxicity of traditional Chinese medicine]. Zhongguo Zhong Yao Za Zhi. 2005 Sep; 30(17):1317-20. View in: Pubmed
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Large dose ketamine inhibits lipopolysaccharide-induced acute lung injury in rats. Inflamm Res. 2005 Mar; 54(3):133-7. View in: Pubmed
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Adjuvant breast cancer treatment: evolution or revolution?. Breast International Group (BIG) Newsletter. 2005; 7(2):1-4. View in: Pubmed
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HER2 inhibition in the adjuvant breast cancer setting. Am J Oncol Rev. 2005; 4(10):17-20. View in: Pubmed
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CNS metastases in breast cancer. J Clin Oncol. 2004 Sep 01; 22(17):3608-17. View in: Pubmed
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New targets for therapy in breast cancer: small molecule tyrosine kinase inhibitors. Breast Cancer Res. 2004; 6(5):204-10. View in: Pubmed
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The predictive value of HER2 and p53 on outcomes after paclitaxel chemotherapy for metastatic breast cancer: Results from CALGB 9342. J Clin Oncol. 2004 Jul 15; 22(14_suppl):9562. View in: Pubmed
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Computational and experimental studies on human misshapen/NIK-related kinase MINK-1. Curr Med Chem. 2004 Mar; 11(5):569-82. View in: Pubmed
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Fatal hepatic necrosis following imatinib mesylate therapy. Blood. 2003 Nov 01; 102(9):3455-6. View in: Pubmed
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BMS-247550 Bristol-Myers Squibb/GBF. Curr Opin Investig Drugs. 2003 Jun; 4(6):746-56. View in: Pubmed
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BMS-247550. Current Opin Investigational Drugs. 2003; 4:746-56. View in: Pubmed
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Therapy-related myelodysplastic syndrome after autologous stem cell transplantation for breast cancer. Leukemia. 2002 Sep; 16(9):1673-9. View in: Pubmed
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Identification and characterization of an isoform of murine Mpl. Biochim Biophys Acta. 2002 Apr 12; 1574(3):383-6. View in: Pubmed
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The comparative RNA web (CRW) site: an online database of comparative sequence and structure information for ribosomal, intron, and other RNAs. BMC Bioinformatics. 2002; 3:2. View in: Pubmed
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Metabolic oscillations in an E. coli fermentation. Biotechnol Bioeng. 2001 Oct 20; 75(2):212-8. View in: Pubmed
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A kinetic study on the interaction of deprotonated purine radical cations with amino acids and model peptides. Biophys Chem. 2001 Feb 15; 89(2-3):193-9. View in: Pubmed
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The expression of Fas/FasL in peripheral blood lymphocytes and the level of IL-2 in serum of patients with condyloma acuminata. J Tongji Med Univ. 2001; 21(2):171-3. View in: Pubmed
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Reaction of reducing hydroxyl radical adducts of pyrimidine nucleotides with riboflavin and flavin adenine dinucleotide (FAD) via electron transfer: a pulse radiolysis study. Biophys Chem. 2000 May 31; 85(1):17-24. View in: Pubmed
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Immediate post-abortal insertion of the frameless GyneFix IUD: initial experience in China. Br J Fam Plann. 2000 Apr; 26(2):85-8. View in: Pubmed
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Evidence for genetic influences common and specific to symptoms of generalized anxiety and panic. J Affect Disord. 2000 Jan-Mar; 57(1-3):25-35. View in: Pubmed
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Social support and depressed mood: a structural analysis. J Health Soc Behav. 1999 Dec; 40(4):344-59. View in: Pubmed
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Reaction of hydroxyl radical with phenylpropanoid glycoside and its derivatives by pulse radiolysis. Sci China C Life Sci. 1999 Aug; 42(4):420-6. View in: Pubmed
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Translocation (4;15)(p16;q24): a novel reciprocal translocation in a patient with BCR/ABL negative myeloproliferative syndrome progressing to blastic phase. Cancer Genet Cytogenet. 1999 May; 111(1):18-20. View in: Pubmed
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Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities. Arch Gen Psychiatry. 1998 Nov; 55(11):967-72. View in: Pubmed
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Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Mol Cell Biol. 1997 Sep; 17(9):5338-47. View in: Pubmed
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[The microspectra of chromosome]. Guang Pu Xue Yu Guang Pu Fen Xi. 1997 Aug; 17(4):21-4. View in: Pubmed
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Vitamin D receptor polymorphisms, bone mineral density, and bone metabolism in postmenopausal Mexican-American women. J Bone Miner Res. 1997 Feb; 12(2):234-40. View in: Pubmed
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Genetic influences on DSM-III-R drug abuse and dependence: a study of 3,372 twin pairs. Am J Med Genet. 1996 Sep 20; 67(5):473-7. View in: Pubmed
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A novel mutation in the deoxyribonucleic acid-binding domain of the vitamin D receptor causes hereditary 1,25-dihydroxyvitamin D-resistant rickets. J Clin Endocrinol Metab. 1996 Jul; 81(7):2564-9. View in: Pubmed
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Reaction of hydroxyl radical with phenylpropanoid glycosides from Pedicularis species: a pulse radiolysis study. Sci China C Life Sci. 1996 Apr; 39(2):154-8. View in: Pubmed
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Urban stress in China. Soc Sci Med. 1995 Oct; 41(8):1131-45. View in: Pubmed
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Subcapsular intratesticular assay: a preliminary screening method for putative male antifertility drugs. Int J Androl. 1995 Jun; 18 Suppl 1:53-7. View in: Pubmed
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Epigenetic lesions at the H19 locus in Wilms' tumour patients. Nat Genet. 1994 07; 7(3):440-7. View in: Pubmed
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Stem cell factor influences the proliferation and erythroid differentiation of the MB-02 human erythroleukemia cell line by binding to a high-affinity c-kit receptor. Blood. 1993 Jul 15; 82(2):436-44. View in: Pubmed
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Polycythemia vera. Further in vitro studies of hematopoietic regulation. J Clin Invest. 1980 Dec; 66(6):1363-8. View in: Pubmed
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Dana-Farber Cancer Institute
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Dana-Farber Cancer Institute
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