Research

CPDM has one of the largest collections of hematologic cancer PDX models of diverse subtypes. These PDX models were first published in Cancer Cell 2016 and subsequently appeared in many studies. This model collection was previously distributed under the Public Repository of Xenografts (PRoXe) by David Weinstock, MD, formerly of Dana-Farber.

See our detailed model lists for more information about our hematologic models. RNA-seq data, whole-exome seq data, and low-pass WGS data are available on cBioPortal. HLA data inferred from RNA-seq data is also available here. Industry users, please refer to Column G in the hematologic models list for distribution permissions.

Learn more about ordering and licensing these models, or email us at models@dfci.harvard.edu to submit an inquiry.

See CPDM's SOPs for working with these models for guidance.

Some of these PDX models have been transduced with the mCLP chemiluminescent marker. Please see the table below.