Neuro-Oncology Clinical Research and Trials

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Clinical Trials Questions?

877-338-7425

The Center for Neuro-Oncology is at the forefront of discovery and development of new treatments for brain and central nervous system tumors. Center investigators have made important inroads in basic and clinical research to better understand the biology that underlies these tumors and identify and test new therapies.

Our researchers are also involved in many projects for the Dana-Farber/Harvard Cancer Center Brain Cancer SPORE (Specialized Program of Research Excellence), including those focused on PI3K inhibitors, IDH mutations, Olig2 suppressors and immunotherapy.

Clinical Trials

Our Center offers a number of exciting clinical trials for patients with primary and metastatic brain and spinal cord tumors. These trials explore several innovative approaches to improve outcomes and quality of life for brain tumor patients, including immunotherapy, targeted therapies, and anti-angiogenesis inhibitors.

Learn more about our clinical trials.

Research Areas

Our research team is leading basic, translational and clinical research aimed at advancing the understanding, diagnosis, and treatment of brain tumors. Areas of focus include:

In addition, we are conducting research on CNS and systemic lymphoma, brain metastasis, adaptive designs for brain tumor clinical trials, neurologic complications of cancer, oncolytic viruses, surgical brain mapping, molecular and cellular surgical oncology, CNS drug delivery/mass spectrometry, preclinical animal models, tumor metabolism/IDH mutations, Olig 2 suppression, and advanced neuro-imaging.

Our Physician-Researchers

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Ennio Chiocca, MD, PhD
Focus: Novel experimental therapies for malignant brain tumors
Chiocca Lab
Dr. Chiocca's Publications

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Brian Alexander, MD, MPH
Dr. Alexander's Publications