Young-Onset Colorectal Cancer Center

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Our Center is among the first in the country dedicated solely to colon and rectal cancer in young adults diagnosed before age 50. Here, we understand the unique set of needs and emotions an early-onset colorectal cancer diagnosis can bring.

Are you over age 50? Patients diagnosed over the age of 50 are encouraged to visit Dana-Farber’s Colon and Rectal Cancer Center.

What is Young-Onset Colorectal Cancer?

Colorectal cancer (CRC) originates in the large intestine – which includes the colon and the rectum – and occurs when cells mutate. The colon is the first six feet of the large intestine, while the remaining several inches form the rectum. You may hear these cancers referred to individually as colon cancer or rectal cancer, depending on where the cancer starts. Colorectal cancer is a name that encompasses both diseases.

Colorectal cancer patients are considered young- or early-onset if they are diagnosed before they turn 50 years old. By the year 2030, colon cancer incidence is expected to double, and rectal cancer incidence is expected to quadruple in this age group.

Risk factors for young-onset colorectal cancer include: a family history of colorectal cancer, a history of inflammatory bowel disease (IBD) such as ulcerative colitis or Crohn's disease, and environmental and lifestyle-related factors such as lack of exercise, obesity, smoking, and alcohol consumption.

Young-Onset Colorectal Cancer: Patrick's Story

One patient shares his story and Dana-Farber's Dr. Kimmie Ng explains how the Center aims to serve the unique needs of younger colon and rectal cancer patients.

Why Choose Dana-Farber for Your Care

Our Unique Focus on Young Adults

As one of the first centers in the country dedicated to treating colorectal cancer in young adults, we deeply understand the unique needs of individuals diagnosed in their 20's, 30's, and 40's. To best serve our patients, we take a multidisciplinary approach to care. Each patient is supported and seen by a team that includes a medical oncologist, surgeon, and radiologist with specific expertise in colorectal cancer. Every patient who is treated at Dana-Farber and diagnosed with colon or rectal cancer before the age of 50 is automatically part of the Young-Onset Colorectal Cancer Center and can benefit from the personalized services we provide.

Learn more about our approach to early-onset colorectal cancer care, including additional details on clinical and supportive care services and patient resources.

Psychosocial Support for Young Colorectal Patients

Our Center is among the only in the country with dedicated psychosocial support for young patients with colorectal cancer and offers programs tailored to their unique needs.

Leading the Way in Research

As a Center that is treating a disease notably on the rise in young people, our top priorities are advancing research to understand this rise and developing new ways to prevent, detect, and treat CRC. This is practiced through both national and Dana-Farber-led studies and clinical trials, all of which are available to our Center’s patients. Your medical oncologist can help you decide whether or not to participate in these research efforts.

Learn more about how we study colorectal cancer and how you can get involved in our Clinical Trials and Research.

Colorectal Cancer Screening: 45 Is the New 50

The colorectal cancer screening age recommendation is now 45. Kimmie Ng, MD explains how the move is prompted by an alarming rise in cases in people younger than 50.

Raising Awareness and Education 

With our team of knowledgeable experts and our Center’s high visibility, we feel a responsibility to continue raising awareness of this disease. We’re passionate about providing educational resources on its symptoms, risk factors, and screening recommendations. In addition, we’re concerned about the alarming upward trend of colorectal cancer in young adults – formerly seen as "an old person's disease" – as well as its disproportionate effect on communities of color – particularly Black Americans.

You can find just some of our awareness-raising work in our media highlights below.

For additional resources offered by our Center, including upcoming educational events, please visit our Events and Resources page.

Colorectal Cancer Screening: Diagnosed at 49

Colorectal Cancer Screening is now recommended for anyone 45 or older. Hear from Katie whose cancer was diagnosed at 49.

Support the Young-Onset Colorectal Cancer Center

Your support will help advance cutting-edge research and specialized care provided to patients under the age of 50 diagnosed with colon or rectal cancer. Your philanthropy can contribute towards:

  • Supporting our groundbreaking research to understand why colorectal cancer rates are rising in young people, and developing new and innovative strategies for prevention, early detection, and treatment
  • Recruiting and mentoring post-doctoral research fellows dedicated to the Center’s research studies
  • Hiring dedicated staff for the Center to help patients and their caregivers navigate their care: a Social Worker to address the specific psychosocial needs of younger adults and their caregivers, a Program and Research Coordinator, and other clinical and support staff
  • Developing new educational materials and programming, such as web and application-based support groups, and other educational opportunities aimed at connecting and empowering young patients
  • Hosting the annual Beyond CRC Forum, a one-day educational conference for individuals with young-onset colorectal cancer and their supporters. In addition to hearing about the latest research and treatment advances, participants are invited to join small interactive sessions with experts on relevant topics such as nutrition and sexual health.

For more information about ways you can become involved with and support the Center, please contact Hillary Repucci at hillaryd_repucci@dfci.harvard.edu or 617-632-6481.

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The Young-Onset Colorectal Cancer Center distributes an e-Newsletter filled with research updates, news from the Center, and patient stories and resources. All are welcome to subscribe.

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